Development of Acid-Resistant Alginate/Trimethyl Chitosan Nanoparticles Containing Cationic β-Cyclodextrin Polymers for Insulin Oral Delivery

AAPS PharmSciTech

Volumn 16, Issue 4, 2015, Pages 952-962

  Mansourpour, Maryam ^a   Mahjub, Reza ^a,b   Amini, Mohsen ^a,c   Ostad, Seyed Naser ^a   Shamsa, Elnaz Sadat ^a   Rafiee Tehrani, Morteza ^a   Dorkoosh, Farid Abedin ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b HAMADAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

alginate; cationic cyclodextrin; insulin nanoparticle; oral delivery; trimethyl chitosan

Indexed keywords

ALGINIC ACID; BETA CYCLODEXTRIN DERIVATIVE; CALCIUM CHLORIDE; CHITOSAN NANOPARTICLE; CHOLINE; INSULIN; METHYL IODIDE; POLYMER; TRIMETHYLCHITOSAN; UNCLASSIFIED DRUG; ACID; BETA CYCLODEXTRIN; CHITOSAN; GLUCURONIC ACID; HEXURONIC ACID;

ARTICLE; CACO 2 CELL LINE; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SYNTHESIS; DRUG UPTAKE; EXPERIMENTAL DESIGN; IN VITRO STUDY; INSULIN RELEASE; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; CACO-2 CELL LINE; CHEMISTRY; HUMAN; ORAL DRUG ADMINISTRATION; PROTON NUCLEAR MAGNETIC RESONANCE;

ACIDS; ADMINISTRATION, ORAL; ALGINATES; BETA-CYCLODEXTRINS; CACO-2 CELLS; CHITOSAN; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; IN VITRO TECHNIQUES; INSULIN; MICROSCOPY, ELECTRON, SCANNING; POLYMERS; PROTON MAGNETIC RESONANCE SPECTROSCOPY;

EID: 84937817815     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-014-0282-9     Document Type: Article

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