The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors

Molecular Cancer

Volumn 14, Issue 1, 2015, Pages

  Pathania, Anup S ^a,b   Wani, Zahoor A ^a   Guru, Santosh K ^a   Kumar, Suresh ^a,b   Bhushan, Shashi ^a   Korkaya, Hasan ^c   Seals, Darren F ^e   Kumar, Ajay ^a   Mondhe, Dilip M ^a   Ahmed, Zabeer ^d   Chandan, Bal K ^d   Malik, Fayaz ^a,b  

^a Natural Product Chemistry Division CSIR Indian Institute of Integrative Medicine   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d Department of Inflammation Pharmacology Indian Institute of Integrative Medicine   (India)

^e APPALACHIAN STATE UNIVERSITY   (United States)

Author keywords

Angiogenesis; Autophagy; BA145; Chloroquinone (CQ); Hypoxia; Light chain protein 3 (LC3); Vascular endothelial growth factor receptor 2 (VEGFR 2)

Indexed keywords

ANTIMALARIAL AGENT; ANTINEOPLASTIC AGENT; BA 145; BOSWELLIC ACID; CHLOROQUINONE; FLUTAMIDE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; ANGIOGENESIS INHIBITOR; INDOLE DERIVATIVE; PYRROLE DERIVATIVE; TRITERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BINDING AFFINITY; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; COLONY FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG EFFICACY; DRUG POTENTIATION; DRUG SAFETY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROSTATE CANCER; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; APOPTOSIS; CELL LINE; CHEMISTRY; DRUG EFFECTS;

ANGIOGENESIS INHIBITORS; ANIMALS; APOPTOSIS; AUTOPHAGY; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INDOLES; PYRROLES; TRITERPENES;

EID: 84937721870     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-14-6     Document Type: Article

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