-
1
-
-
0034129118
-
Recent advances in research on multistage tumorigenesis
-
Compagni A, Christofori G. Recent advances in research on multistage tumorigenesis. Br J Cancer 2000;83:1-5.
-
(2000)
Br J Cancer
, vol.83
, pp. 1-5
-
-
Compagni, A.1
Christofori, G.2
-
2
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005;438:967-74.
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
4
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
5
-
-
34548850080
-
Molecular design and clinical development of VEGFR kinase inhibitors
-
Zhong H, Bowen JP. Molecular design and clinical development of VEGFR kinase inhibitors. Curr Top Med Chem 2007;7:1379-93.
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 1379-1393
-
-
Zhong, H.1
Bowen, J.P.2
-
6
-
-
54549084611
-
Basic science of angiogenesis and its progress in clinical application
-
Takakura N. Basic science of angiogenesis and its progress in clinical application. Rinsho Ketsueki 2008;49:1451-59.
-
(2008)
Rinsho Ketsueki
, vol.49
, pp. 1451-1459
-
-
Takakura, N.1
-
7
-
-
30744479430
-
Angiogenesis in life, disease and medicine
-
Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005;438:932-6.
-
(2005)
Nature
, vol.438
, pp. 932-936
-
-
Carmeliet, P.1
-
8
-
-
33749028188
-
Vascular endothelial growth factor signaling pathways: Therapeutic perspective
-
Kowanetz M, Ferrara N. Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res 2006;12:5018-22.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5018-5022
-
-
Kowanetz, M.1
Ferrara, N.2
-
9
-
-
0034603197
-
New roles for Src kinases in control of cell survival and angiogenesis
-
Schlessinger J. New roles for Src kinases in control of cell survival and angiogenesis. Cell 2000;100:293-6.
-
(2000)
Cell
, vol.100
, pp. 293-296
-
-
Schlessinger, J.1
-
10
-
-
54249141519
-
Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis
-
Liu LZ, Zheng JZ, Wang XR, Jiang BH. Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis. Cancer Res 2008;68:8183-8.
-
(2008)
Cancer Res
, vol.68
, pp. 8183-8188
-
-
Liu, L.Z.1
Zheng, J.Z.2
Wang, X.R.3
Jiang, B.H.4
-
11
-
-
25844484590
-
Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor
-
Wong C, Jin ZG. Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor. J Biol Chem 2005;280:33262-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 33262-33269
-
-
Wong, C.1
Jin, Z.G.2
-
12
-
-
33746565515
-
Role of Raf kinase in cancer: Therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway
-
Gollob JA, Wilhelm S, Carter C, Kelley SL. Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway. Semin Oncol 2006;33:392-406.
-
(2006)
Semin Oncol
, vol.33
, pp. 392-406
-
-
Gollob, J.A.1
Wilhelm, S.2
Carter, C.3
Kelley, S.L.4
-
13
-
-
10844262511
-
Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-α induction in monocytes by direct interaction with IκB kinases
-
Syrovets T, Buchele B, Krauss C, Laumonnier Y, Simmet T. Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-α induction in monocytes by direct interaction with IκB kinases. J Immunol 2005;174:498-506.
-
(2005)
J Immunol
, vol.174
, pp. 498-506
-
-
Syrovets, T.1
Buchele, B.2
Krauss, C.3
Laumonnier, Y.4
Simmet, T.5
-
14
-
-
33644536397
-
Acetyl-11-keto-β- boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-κB and NF-κB-regulated gene expression
-
Takada Y, Ichikawa H, Badmaev V, Aggarwal BB. Acetyl-11-keto-β- boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-κB and NF-κB-regulated gene expression. J Immunol 2006;176:3127-40.
-
(2006)
J Immunol
, vol.176
, pp. 3127-3140
-
-
Takada, Y.1
Ichikawa, H.2
Badmaev, V.3
Aggarwal, B.B.4
-
15
-
-
0026624938
-
Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase
-
Safayhi H, Mack T, Sabieraj J, Anazodo MI, Subramanian LR, Ammon HP. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharmacol ExpTher 1992;261:1143-6.
-
(1992)
J Pharmacol ExpTher
, vol.261
, pp. 1143-1146
-
-
Safayhi, H.1
Mack, T.2
Sabieraj, J.3
Anazodo, M.I.4
Subramanian, L.R.5
Ammon, H.P.6
-
16
-
-
0029035973
-
Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-β-boswellic acid
-
Safayhi H, Sailer ER, Ammon HP. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-β-boswellic acid. Mol Pharmacol 1995;47:1212-6.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 1212-1216
-
-
Safayhi, H.1
Sailer, E.R.2
Ammon, H.P.3
-
17
-
-
32344443550
-
Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-β boswellic acid
-
Bishnoi M, Patil CS, Kumar A, Kulkarni SK. Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-β boswellic acid. Indian J ExpBiol 2006;44:128-32.
-
(2006)
Indian J ExpBiol
, vol.44
, pp. 128-132
-
-
Bishnoi, M.1
Patil, C.S.2
Kumar, A.3
Kulkarni, S.K.4
-
18
-
-
33845321884
-
Boswellic acids: Biological actions and molecular targets
-
Poeckel D, Werz O. Boswellic acids: biological actions and molecular targets. Curr Med Chem 2006; 13:3359-69.
-
(2006)
Curr Med Chem
, vol.13
, pp. 3359-3369
-
-
Poeckel, D.1
Werz, O.2
-
20
-
-
0036949876
-
Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells
-
Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93.
-
(2002)
Carcinogenesis
, vol.23
, pp. 2087-2093
-
-
Liu, J.J.1
Nilsson, A.2
Oredsson, S.3
Badmaev, V.4
Zhao, W.Z.5
Duan, R.D.6
-
21
-
-
39449093377
-
Acetyl-keto-β-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells
-
Lu M, Xia L, Hua H, Jing Y. Acetyl-keto-β-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells. Cancer Res 2008;68:1180-6.
-
(2008)
Cancer Res
, vol.68
, pp. 1180-1186
-
-
Lu, M.1
Xia, L.2
Hua, H.3
Jing, Y.4
-
22
-
-
0242500941
-
Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells
-
Zhao W, Entschladen F, Liu H, et al. Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. Cancer Detect Prev 2003;27:67-75.
-
(2003)
Cancer Detect Prev
, vol.27
, pp. 67-75
-
-
Zhao, W.1
Entschladen, F.2
Liu, H.3
-
23
-
-
0036780654
-
Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway
-
Liu JJ, Nilsson A, Oredsson S, Badmaev V, Duan RD. Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway. Int J Mol Med 2002;10:501-5.
-
(2002)
Int J Mol Med
, vol.10
, pp. 501-505
-
-
Liu, J.J.1
Nilsson, A.2
Oredsson, S.3
Badmaev, V.4
Duan, R.D.5
-
24
-
-
0032895637
-
Boswellic acids and malignant glioma: Induction of apoptosis but no modulation of drug sensitivity
-
Glaser T, Winter S, Groscurth P, et al. Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. Br J Cancer 1999;80:756-65.
-
(1999)
Br J Cancer
, vol.80
, pp. 756-765
-
-
Glaser, T.1
Winter, S.2
Groscurth, P.3
-
25
-
-
0036765655
-
Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro
-
Hostanska K, Daum G, Saller R. Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. Anticancer Res 2002;22:2853-62.
-
(2002)
Anticancer Res
, vol.22
, pp. 2853-2862
-
-
Hostanska, K.1
Daum, G.2
Saller, R.3
-
26
-
-
58349092759
-
Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways
-
Pang X, Yi T, Yi Z, et al. Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways. Cancer Res 2009;69:518-25.
-
(2009)
Cancer Res
, vol.69
, pp. 518-525
-
-
Pang, X.1
Yi, T.2
Yi, Z.3
-
27
-
-
40949101023
-
Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
-
Yi T, Yi Z, Cho SG, et al. Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Res 2008;68:1843-50.
-
(2008)
Cancer Res
, vol.68
, pp. 1843-1850
-
-
Yi, T.1
Yi, Z.2
Cho, S.G.3
-
28
-
-
39149100314
-
Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity
-
Pyun BJ, Choi S, Lee Y, et al. Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity. Cancer Res 2008;68:227-35.
-
(2008)
Cancer Res
, vol.68
, pp. 227-235
-
-
Pyun, B.J.1
Choi, S.2
Lee, Y.3
-
29
-
-
2342430184
-
Vasculogenesis and angiogenesis
-
Patan S. Vasculogenesis and angiogenesis. Cancer Treat Res 2004;117:3-32.
-
(2004)
Cancer Treat Res
, vol.117
, pp. 3-32
-
-
Patan, S.1
-
31
-
-
33750842076
-
Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis
-
Shibuya M. Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. J Biochem Mol Biol 2006;39:469-78.
-
(2006)
J Biochem Mol Biol
, vol.39
, pp. 469-478
-
-
Shibuya, M.1
-
32
-
-
33847698964
-
Effect of acetyl 11-keto β-boswellic acid on metastatic growth factor responsible for angiogenesis
-
Singh SK, Bhusari S, Singh R, Saxena A, Mondhe D, Qazi GN. Effect of acetyl 11-keto β-boswellic acid on metastatic growth factor responsible for angiogenesis. Vascul Pharmacol 2007;46:333-7.
-
(2007)
Vascul Pharmacol
, vol.46
, pp. 333-337
-
-
Singh, S.K.1
Bhusari, S.2
Singh, R.3
Saxena, A.4
Mondhe, D.5
Qazi, G.N.6
-
33
-
-
52049106205
-
The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway
-
Roodhart JM, Langenberg MH, Witteveen E, Voest EE. The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway. Curr Clin Pharmacol 2008;3:132-43.
-
(2008)
Curr Clin Pharmacol
, vol.3
, pp. 132-143
-
-
Roodhart, J.M.1
Langenberg, M.H.2
Witteveen, E.3
Voest, E.E.4
-
34
-
-
34548065791
-
Non-receptor protein-tyrosine kinases as molecular targets for antiangiogenic therapy
-
Kanda S, Miyata Y, Kanetake H, Smithgall TE. Non-receptor protein-tyrosine kinases as molecular targets for antiangiogenic therapy. Int J Mol Med 2007;20:113-21.
-
(2007)
Int J Mol Med
, vol.20
, pp. 113-121
-
-
Kanda, S.1
Miyata, Y.2
Kanetake, H.3
Smithgall, T.E.4
-
35
-
-
34248397608
-
Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells
-
Chou MT, Wang J, Fujita DJ. Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells. BMC Biochem 2002;3:32.
-
(2002)
BMC Biochem
, vol.3
, pp. 32
-
-
Chou, M.T.1
Wang, J.2
Fujita, D.J.3
-
36
-
-
21744435561
-
A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration
-
Ali N, Yoshizumi M, Fujita Y, et al. A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration. J Pharmacol Sci 2005;98:130-41.
-
(2005)
J Pharmacol Sci
, vol.98
, pp. 130-141
-
-
Ali, N.1
Yoshizumi, M.2
Fujita, Y.3
-
37
-
-
33748286819
-
Integrin-regulated FAK-Src signaling in normal and cancer cells
-
Mitra SK, Schlaepfer DD. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 2006;18:516-23.
-
(2006)
Curr Opin Cell Biol
, vol.18
, pp. 516-523
-
-
Mitra, S.K.1
Schlaepfer, D.D.2
-
38
-
-
34447257690
-
Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells
-
Matsuo M, Yamada S, Koizumi K, Sakurai H, Saiki I. Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells. Eur J Cancer 2007;43:1748-54.
-
(2007)
Eur J Cancer
, vol.43
, pp. 1748-1754
-
-
Matsuo, M.1
Yamada, S.2
Koizumi, K.3
Sakurai, H.4
Saiki, I.5
-
39
-
-
54949110530
-
Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma
-
Li W, Tan D, Zhang Z, Liang JJ, Brown RE. Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma. Oncol Rep 2008;20:713-9.
-
(2008)
Oncol Rep
, vol.20
, pp. 713-719
-
-
Li, W.1
Tan, D.2
Zhang, Z.3
Liang, J.J.4
Brown, R.E.5
-
40
-
-
50349091316
-
Combination strategy targeting the hypoxia inducible factor-1a with mammalian target of rapamycin and histone deacetylase inhibitors
-
Verheul HM, Salumbides B, Van ErpK, et al. Combination strategy targeting the hypoxia inducible factor-1a with mammalian target of rapamycin and histone deacetylase inhibitors. Clin Cancer Res 2008;14:3589-97.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3589-3597
-
-
Verheul, H.M.1
Salumbides, B.2
ErpK, V.3
-
41
-
-
59549107896
-
Silibinin inhibits hypoxiainducible factor-1a and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: Implications for anticancer therapy
-
Garcia-Maceira P, Mateo J. Silibinin inhibits hypoxiainducible factor-1a and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy. Oncogene 2009;28:313-24.
-
(2009)
Oncogene
, vol.28
, pp. 313-324
-
-
Garcia-Maceira, P.1
Mateo, J.2
-
42
-
-
54549089738
-
Hypoxia signalling through mTOR and the unfolded protein response in cancer
-
Wouters BG, Koritzinsky M. Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 2008;8:851-64.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 851-864
-
-
Wouters, B.G.1
Koritzinsky, M.2
|