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Volumn 69, Issue 14, 2009, Pages 5893-5900

Acetyl-11-keto-β-boswellic acid inhibits prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL 11 KETA BETA BOSWELLIC ACID; ANTINEOPLASTIC AGENT; BOSWELLIA SERRATA EXTRACT; FOCAL ADHESION KINASE; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; S6 KINASE; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

EID: 67651005688     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-0755     Document Type: Article
Times cited : (193)

References (42)
  • 1
    • 0034129118 scopus 로고    scopus 로고
    • Recent advances in research on multistage tumorigenesis
    • Compagni A, Christofori G. Recent advances in research on multistage tumorigenesis. Br J Cancer 2000;83:1-5.
    • (2000) Br J Cancer , vol.83 , pp. 1-5
    • Compagni, A.1    Christofori, G.2
  • 2
    • 30744449235 scopus 로고    scopus 로고
    • Angiogenesis as a therapeutic target
    • Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005;438:967-74.
    • (2005) Nature , vol.438 , pp. 967-974
    • Ferrara, N.1    Kerbel, R.S.2
  • 3
    • 33745305095 scopus 로고    scopus 로고
    • Anti-angiogenic drugs: From bench to clinical trials
    • Quesada AR, Munoz-Chapuli R, Medina MA. Anti-angiogenic drugs: from bench to clinical trials. Med Res Rev 2006;26:483-530.
    • (2006) Med Res Rev , vol.26 , pp. 483-530
    • Quesada, A.R.1    Munoz-Chapuli, R.2    Medina, M.A.3
  • 4
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 34548850080 scopus 로고    scopus 로고
    • Molecular design and clinical development of VEGFR kinase inhibitors
    • Zhong H, Bowen JP. Molecular design and clinical development of VEGFR kinase inhibitors. Curr Top Med Chem 2007;7:1379-93.
    • (2007) Curr Top Med Chem , vol.7 , pp. 1379-1393
    • Zhong, H.1    Bowen, J.P.2
  • 6
    • 54549084611 scopus 로고    scopus 로고
    • Basic science of angiogenesis and its progress in clinical application
    • Takakura N. Basic science of angiogenesis and its progress in clinical application. Rinsho Ketsueki 2008;49:1451-59.
    • (2008) Rinsho Ketsueki , vol.49 , pp. 1451-1459
    • Takakura, N.1
  • 7
    • 30744479430 scopus 로고    scopus 로고
    • Angiogenesis in life, disease and medicine
    • Carmeliet P. Angiogenesis in life, disease and medicine. Nature 2005;438:932-6.
    • (2005) Nature , vol.438 , pp. 932-936
    • Carmeliet, P.1
  • 8
    • 33749028188 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signaling pathways: Therapeutic perspective
    • Kowanetz M, Ferrara N. Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin Cancer Res 2006;12:5018-22.
    • (2006) Clin Cancer Res , vol.12 , pp. 5018-5022
    • Kowanetz, M.1    Ferrara, N.2
  • 9
    • 0034603197 scopus 로고    scopus 로고
    • New roles for Src kinases in control of cell survival and angiogenesis
    • Schlessinger J. New roles for Src kinases in control of cell survival and angiogenesis. Cell 2000;100:293-6.
    • (2000) Cell , vol.100 , pp. 293-296
    • Schlessinger, J.1
  • 10
    • 54249141519 scopus 로고    scopus 로고
    • Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis
    • Liu LZ, Zheng JZ, Wang XR, Jiang BH. Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis. Cancer Res 2008;68:8183-8.
    • (2008) Cancer Res , vol.68 , pp. 8183-8188
    • Liu, L.Z.1    Zheng, J.Z.2    Wang, X.R.3    Jiang, B.H.4
  • 11
    • 25844484590 scopus 로고    scopus 로고
    • Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor
    • Wong C, Jin ZG. Protein kinase C-dependent protein kinase D activation modulates ERK signal pathway and endothelial cell proliferation by vascular endothelial growth factor. J Biol Chem 2005;280:33262-9.
    • (2005) J Biol Chem , vol.280 , pp. 33262-33269
    • Wong, C.1    Jin, Z.G.2
  • 12
    • 33746565515 scopus 로고    scopus 로고
    • Role of Raf kinase in cancer: Therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway
    • Gollob JA, Wilhelm S, Carter C, Kelley SL. Role of Raf kinase in cancer: therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway. Semin Oncol 2006;33:392-406.
    • (2006) Semin Oncol , vol.33 , pp. 392-406
    • Gollob, J.A.1    Wilhelm, S.2    Carter, C.3    Kelley, S.L.4
  • 13
    • 10844262511 scopus 로고    scopus 로고
    • Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-α induction in monocytes by direct interaction with IκB kinases
    • Syrovets T, Buchele B, Krauss C, Laumonnier Y, Simmet T. Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-α induction in monocytes by direct interaction with IκB kinases. J Immunol 2005;174:498-506.
    • (2005) J Immunol , vol.174 , pp. 498-506
    • Syrovets, T.1    Buchele, B.2    Krauss, C.3    Laumonnier, Y.4    Simmet, T.5
  • 14
    • 33644536397 scopus 로고    scopus 로고
    • Acetyl-11-keto-β- boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-κB and NF-κB-regulated gene expression
    • Takada Y, Ichikawa H, Badmaev V, Aggarwal BB. Acetyl-11-keto-β- boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-κB and NF-κB-regulated gene expression. J Immunol 2006;176:3127-40.
    • (2006) J Immunol , vol.176 , pp. 3127-3140
    • Takada, Y.1    Ichikawa, H.2    Badmaev, V.3    Aggarwal, B.B.4
  • 16
    • 0029035973 scopus 로고
    • Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-β-boswellic acid
    • Safayhi H, Sailer ER, Ammon HP. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-β-boswellic acid. Mol Pharmacol 1995;47:1212-6.
    • (1995) Mol Pharmacol , vol.47 , pp. 1212-1216
    • Safayhi, H.1    Sailer, E.R.2    Ammon, H.P.3
  • 17
    • 32344443550 scopus 로고    scopus 로고
    • Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-β boswellic acid
    • Bishnoi M, Patil CS, Kumar A, Kulkarni SK. Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-β boswellic acid. Indian J ExpBiol 2006;44:128-32.
    • (2006) Indian J ExpBiol , vol.44 , pp. 128-132
    • Bishnoi, M.1    Patil, C.S.2    Kumar, A.3    Kulkarni, S.K.4
  • 18
    • 33845321884 scopus 로고    scopus 로고
    • Boswellic acids: Biological actions and molecular targets
    • Poeckel D, Werz O. Boswellic acids: biological actions and molecular targets. Curr Med Chem 2006; 13:3359-69.
    • (2006) Curr Med Chem , vol.13 , pp. 3359-3369
    • Poeckel, D.1    Werz, O.2
  • 20
    • 0036949876 scopus 로고    scopus 로고
    • Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells
    • Liu JJ, Nilsson A, Oredsson S, Badmaev V, Zhao WZ, Duan RD. Boswellic acids trigger apoptosis via a pathway dependent on caspase-8 activation but independent on Fas/Fas ligand interaction in colon cancer HT-29 cells. Carcinogenesis 2002;23:2087-93.
    • (2002) Carcinogenesis , vol.23 , pp. 2087-2093
    • Liu, J.J.1    Nilsson, A.2    Oredsson, S.3    Badmaev, V.4    Zhao, W.Z.5    Duan, R.D.6
  • 21
    • 39449093377 scopus 로고    scopus 로고
    • Acetyl-keto-β-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells
    • Lu M, Xia L, Hua H, Jing Y. Acetyl-keto-β-boswellic acid induces apoptosis through a death receptor 5-mediated pathway in prostate cancer cells. Cancer Res 2008;68:1180-6.
    • (2008) Cancer Res , vol.68 , pp. 1180-1186
    • Lu, M.1    Xia, L.2    Hua, H.3    Jing, Y.4
  • 22
    • 0242500941 scopus 로고    scopus 로고
    • Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells
    • Zhao W, Entschladen F, Liu H, et al. Boswellic acid acetate induces differentiation and apoptosis in highly metastatic melanoma and fibrosarcoma cells. Cancer Detect Prev 2003;27:67-75.
    • (2003) Cancer Detect Prev , vol.27 , pp. 67-75
    • Zhao, W.1    Entschladen, F.2    Liu, H.3
  • 23
    • 0036780654 scopus 로고    scopus 로고
    • Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway
    • Liu JJ, Nilsson A, Oredsson S, Badmaev V, Duan RD. Keto- and acetyl-keto-boswellic acids inhibit proliferation and induce apoptosis in Hep G2 cells via a caspase-8 dependent pathway. Int J Mol Med 2002;10:501-5.
    • (2002) Int J Mol Med , vol.10 , pp. 501-505
    • Liu, J.J.1    Nilsson, A.2    Oredsson, S.3    Badmaev, V.4    Duan, R.D.5
  • 24
    • 0032895637 scopus 로고    scopus 로고
    • Boswellic acids and malignant glioma: Induction of apoptosis but no modulation of drug sensitivity
    • Glaser T, Winter S, Groscurth P, et al. Boswellic acids and malignant glioma: induction of apoptosis but no modulation of drug sensitivity. Br J Cancer 1999;80:756-65.
    • (1999) Br J Cancer , vol.80 , pp. 756-765
    • Glaser, T.1    Winter, S.2    Groscurth, P.3
  • 25
    • 0036765655 scopus 로고    scopus 로고
    • Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro
    • Hostanska K, Daum G, Saller R. Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro. Anticancer Res 2002;22:2853-62.
    • (2002) Anticancer Res , vol.22 , pp. 2853-2862
    • Hostanska, K.1    Daum, G.2    Saller, R.3
  • 26
    • 58349092759 scopus 로고    scopus 로고
    • Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways
    • Pang X, Yi T, Yi Z, et al. Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and extracellular signal-regulated kinase signaling pathways. Cancer Res 2009;69:518-25.
    • (2009) Cancer Res , vol.69 , pp. 518-525
    • Pang, X.1    Yi, T.2    Yi, Z.3
  • 27
    • 40949101023 scopus 로고    scopus 로고
    • Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
    • Yi T, Yi Z, Cho SG, et al. Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. Cancer Res 2008;68:1843-50.
    • (2008) Cancer Res , vol.68 , pp. 1843-1850
    • Yi, T.1    Yi, Z.2    Cho, S.G.3
  • 28
    • 39149100314 scopus 로고    scopus 로고
    • Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity
    • Pyun BJ, Choi S, Lee Y, et al. Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity. Cancer Res 2008;68:227-35.
    • (2008) Cancer Res , vol.68 , pp. 227-235
    • Pyun, B.J.1    Choi, S.2    Lee, Y.3
  • 29
    • 2342430184 scopus 로고    scopus 로고
    • Vasculogenesis and angiogenesis
    • Patan S. Vasculogenesis and angiogenesis. Cancer Treat Res 2004;117:3-32.
    • (2004) Cancer Treat Res , vol.117 , pp. 3-32
    • Patan, S.1
  • 31
    • 33750842076 scopus 로고    scopus 로고
    • Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis
    • Shibuya M. Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. J Biochem Mol Biol 2006;39:469-78.
    • (2006) J Biochem Mol Biol , vol.39 , pp. 469-478
    • Shibuya, M.1
  • 32
    • 33847698964 scopus 로고    scopus 로고
    • Effect of acetyl 11-keto β-boswellic acid on metastatic growth factor responsible for angiogenesis
    • Singh SK, Bhusari S, Singh R, Saxena A, Mondhe D, Qazi GN. Effect of acetyl 11-keto β-boswellic acid on metastatic growth factor responsible for angiogenesis. Vascul Pharmacol 2007;46:333-7.
    • (2007) Vascul Pharmacol , vol.46 , pp. 333-337
    • Singh, S.K.1    Bhusari, S.2    Singh, R.3    Saxena, A.4    Mondhe, D.5    Qazi, G.N.6
  • 33
    • 52049106205 scopus 로고    scopus 로고
    • The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway
    • Roodhart JM, Langenberg MH, Witteveen E, Voest EE. The molecular basis of class side effects due to treatment with inhibitors of the VEGF/VEGFR pathway. Curr Clin Pharmacol 2008;3:132-43.
    • (2008) Curr Clin Pharmacol , vol.3 , pp. 132-143
    • Roodhart, J.M.1    Langenberg, M.H.2    Witteveen, E.3    Voest, E.E.4
  • 34
    • 34548065791 scopus 로고    scopus 로고
    • Non-receptor protein-tyrosine kinases as molecular targets for antiangiogenic therapy
    • Kanda S, Miyata Y, Kanetake H, Smithgall TE. Non-receptor protein-tyrosine kinases as molecular targets for antiangiogenic therapy. Int J Mol Med 2007;20:113-21.
    • (2007) Int J Mol Med , vol.20 , pp. 113-121
    • Kanda, S.1    Miyata, Y.2    Kanetake, H.3    Smithgall, T.E.4
  • 35
    • 34248397608 scopus 로고    scopus 로고
    • Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells
    • Chou MT, Wang J, Fujita DJ. Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells. BMC Biochem 2002;3:32.
    • (2002) BMC Biochem , vol.3 , pp. 32
    • Chou, M.T.1    Wang, J.2    Fujita, D.J.3
  • 36
    • 21744435561 scopus 로고    scopus 로고
    • A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration
    • Ali N, Yoshizumi M, Fujita Y, et al. A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration. J Pharmacol Sci 2005;98:130-41.
    • (2005) J Pharmacol Sci , vol.98 , pp. 130-141
    • Ali, N.1    Yoshizumi, M.2    Fujita, Y.3
  • 37
    • 33748286819 scopus 로고    scopus 로고
    • Integrin-regulated FAK-Src signaling in normal and cancer cells
    • Mitra SK, Schlaepfer DD. Integrin-regulated FAK-Src signaling in normal and cancer cells. Curr Opin Cell Biol 2006;18:516-23.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 516-523
    • Mitra, S.K.1    Schlaepfer, D.D.2
  • 38
    • 34447257690 scopus 로고    scopus 로고
    • Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells
    • Matsuo M, Yamada S, Koizumi K, Sakurai H, Saiki I. Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells. Eur J Cancer 2007;43:1748-54.
    • (2007) Eur J Cancer , vol.43 , pp. 1748-1754
    • Matsuo, M.1    Yamada, S.2    Koizumi, K.3    Sakurai, H.4    Saiki, I.5
  • 39
    • 54949110530 scopus 로고    scopus 로고
    • Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma
    • Li W, Tan D, Zhang Z, Liang JJ, Brown RE. Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma. Oncol Rep 2008;20:713-9.
    • (2008) Oncol Rep , vol.20 , pp. 713-719
    • Li, W.1    Tan, D.2    Zhang, Z.3    Liang, J.J.4    Brown, R.E.5
  • 40
    • 50349091316 scopus 로고    scopus 로고
    • Combination strategy targeting the hypoxia inducible factor-1a with mammalian target of rapamycin and histone deacetylase inhibitors
    • Verheul HM, Salumbides B, Van ErpK, et al. Combination strategy targeting the hypoxia inducible factor-1a with mammalian target of rapamycin and histone deacetylase inhibitors. Clin Cancer Res 2008;14:3589-97.
    • (2008) Clin Cancer Res , vol.14 , pp. 3589-3597
    • Verheul, H.M.1    Salumbides, B.2    ErpK, V.3
  • 41
    • 59549107896 scopus 로고    scopus 로고
    • Silibinin inhibits hypoxiainducible factor-1a and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: Implications for anticancer therapy
    • Garcia-Maceira P, Mateo J. Silibinin inhibits hypoxiainducible factor-1a and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy. Oncogene 2009;28:313-24.
    • (2009) Oncogene , vol.28 , pp. 313-324
    • Garcia-Maceira, P.1    Mateo, J.2
  • 42
    • 54549089738 scopus 로고    scopus 로고
    • Hypoxia signalling through mTOR and the unfolded protein response in cancer
    • Wouters BG, Koritzinsky M. Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer 2008;8:851-64.
    • (2008) Nat Rev Cancer , vol.8 , pp. 851-864
    • Wouters, B.G.1    Koritzinsky, M.2


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