Impact of a synthetic cannabinoid (CP-47,497-C8) on protein expression in human cells: evidence for induction of inflammation and DNA damage

Archives of Toxicology

Volumn 90, Issue 6, 2016, Pages 1369-1382

  Bileck, Andrea ^a   Ferk, Franziska ^b   Al Serori, Halh ^b   Koller, Verena J ^b   Muqaku, Besnik ^a   Haslberger, Alexander ^a   Auwärter, Volker ^c   Gerner, Christopher ^a   Knasmüller, Siegfried ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF VIENNA   (Austria)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Comet assay; Lymphocytes; Proteomics; Synthetic cannabinoid

Indexed keywords

CANNABICYCLOHEXANOL; CANNABINOID; CANNABINOID RECEPTOR; DNA; INTERLEUKIN 12P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PHENOL DERIVATIVE; PROTEOME; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-(2-HYDROXY-4-(2-METHYLNONAN-2-YL)PHENYL)CYCLOHEXAN-1-OL; CYCLOHEXANOL DERIVATIVE; CYTOKINE; NUCLEAR PROTEIN;

ADULT; ARTICLE; CELL FRACTIONATION; CHROMOSOME ABERRATION; COMET ASSAY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINESIS; CYTOSOL; DNA DAMAGE; DNA REPAIR; DOWN REGULATION; GENOMIC INSTABILITY; GENOTOXICITY; HUMAN; HUMAN CELL; INFLAMMATION; LIPID METABOLISM; LYMPHOCYTE; MALE; MICRONUCLEUS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECTS; IMMUNOLOGY; LIQUID CHROMATOGRAPHY; LYMPHOCYTE ACTIVATION; MASS SPECTROMETRY; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; PROTEIN MICROARRAY; PROTEIN SYNTHESIS;

ADULT; CANNABINOIDS; CELLS, CULTURED; CHROMATOGRAPHY, LIQUID; COMET ASSAY; CYCLOHEXANOLS; CYTOKINES; DNA DAMAGE; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MASS SPECTROMETRY; NUCLEAR PROTEINS; PHENOLS; PROTEIN ARRAY ANALYSIS; PROTEIN BIOSYNTHESIS; SUBCELLULAR FRACTIONS;

EID: 84937622342     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-015-1569-7     Document Type: Article

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