Comprehensive assessment of proteins regulated by dexamethasone reveals novel effects in primary human peripheral blood mononuclear cells

Journal of Proteome Research

Volumn 13, Issue 12, 2014, Pages 5989-6000

  Bileck, Andrea ^a   Kreutz, Dominique ^a   Muqaku, Besnik ^a   Slany, Astrid ^a   Gerner, Christopher ^a  

^a Institute of Analytical Chemistry   (Austria)

Author keywords

Adverse drug effects; cell biology; drug effects; inflammatory response; mass spectrometry; PBMCs; proteomics; secretome

Indexed keywords

CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; DEXAMETHASONE; INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 6; PENTRAXIN 3; PLASMA PROTEIN; PROTEIN; PROTEOME; TSG 6 PROTEIN; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; C REACTIVE PROTEIN; CELL ADHESION MOLECULE; CXCL2 PROTEIN, HUMAN; SERUM AMYLOID P; TNFAIP6 PROTEIN, HUMAN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INFLAMMATION; MASS SPECTROMETRY; MULTIPLE REACTION MONITORING; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN ANALYSIS; PROTEIN TARGETING; PROTEOMICS; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; CELL CULTURE; DOWN REGULATION; DRUG EFFECTS; LIQUID CHROMATOGRAPHY; METABOLISM; MONONUCLEAR CELL; PROCEDURES; UPREGULATION;

ANTI-INFLAMMATORY AGENTS; C-REACTIVE PROTEIN; CELL ADHESION MOLECULES; CELLS, CULTURED; CHEMOKINE CXCL1; CHEMOKINE CXCL2; CHROMATOGRAPHY, LIQUID; DEXAMETHASONE; DOWN-REGULATION; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; MASS SPECTROMETRY; PROTEOME; PROTEOMICS; SERUM AMYLOID P-COMPONENT; UP-REGULATION;

EID: 84915747785     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr5008625     Document Type: Article

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