메뉴 건너뛰기




Volumn 3, Issue 8, 2009, Pages 947-967

Proteomics reveals acute pro-inflammatory and protective responses in rat Kupffer cells and hepatocytes after chemical initiation of liver cancer and after LPS and IL-6

Author keywords

Hepatocarcinogenesis; Hepatocytes; Inflammation; Kupffer cells; N nitrosomorpholine

Indexed keywords

ACUTE PHASE PROTEIN; CHEMOKINE; CYTOKINE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITROSOMORPHOLINE; PROTEINASE;

EID: 70350221826     PISSN: 18628346     EISSN: None     Source Type: Journal    
DOI: 10.1002/prca.200800173     Document Type: Article
Times cited : (10)

References (91)
  • 3
    • 33745499905 scopus 로고    scopus 로고
    • Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress
    • Seitz, H. K., Stickel, F., Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress. Biol. Chem. 2006, 387, 349-360.
    • (2006) Biol. Chem , vol.387 , pp. 349-360
    • Seitz, H.K.1    Stickel, F.2
  • 4
    • 4644335311 scopus 로고    scopus 로고
    • Cancer: An inflammatory link
    • Balkwill, F., Coussens, L. M., Cancer: an inflammatory link. Nature 2004, 431, 405-406.
    • (2004) Nature , vol.431 , pp. 405-406
    • Balkwill, F.1    Coussens, L.M.2
  • 5
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L. M., Werb, Z., Inflammation and cancer. Nature 2002, 420, 860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 6
    • 33746040164 scopus 로고    scopus 로고
    • The inflammatory tumor microenvironment and its impact on cancer development
    • de Visser, K. E., Coussens, L. M., The inflammatory tumor microenvironment and its impact on cancer development. Contrib. Microbiol. 2006, 13, 118-137.
    • (2006) Contrib. Microbiol , vol.13 , pp. 118-137
    • de Visser, K.E.1    Coussens, L.M.2
  • 7
    • 34047210411 scopus 로고    scopus 로고
    • TP53 mutations and hepatocellular carcinoma: Insights into the etiology and pathogenesis of liver cancer
    • Hussain, S. P., Schwank, J., Staib, F., Wang, X. W., Harris, C. C., TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer. Oncogene 2007, 26, 2166-2176.
    • (2007) Oncogene , vol.26 , pp. 2166-2176
    • Hussain, S.P.1    Schwank, J.2    Staib, F.3    Wang, X.W.4    Harris, C.C.5
  • 8
    • 0141526160 scopus 로고    scopus 로고
    • Hepatitis B virus and hepatocellular carcinoma
    • Bruix, J., Llovet, J. M., Hepatitis B virus and hepatocellular carcinoma. J. Hepatol. 2003, 39, S59-S63.
    • (2003) J. Hepatol , vol.39
    • Bruix, J.1    Llovet, J.M.2
  • 9
    • 33847363203 scopus 로고    scopus 로고
    • Models of liver fibrosis: Exploring the dynamic nature of inflammation and repair in a solid organ
    • Iredale, J. P., Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J. Clin. Invest. 2007, 117, 539-548.
    • (2007) J. Clin. Invest , vol.117 , pp. 539-548
    • Iredale, J.P.1
  • 10
    • 33745527481 scopus 로고    scopus 로고
    • Viral hepatitis and liver cancer: The case of hepatitis C
    • Levrero, M., Viral hepatitis and liver cancer: the case of hepatitis C. Oncogene 2006, 25, 3834-3847.
    • (2006) Oncogene , vol.25 , pp. 3834-3847
    • Levrero, M.1
  • 11
    • 0022560283 scopus 로고
    • Hepatocarcinogenesis in the rat: The effect of promoters and carcinogens in vivo and in vitro
    • Moore, M. A., Kitagawa, T., Hepatocarcinogenesis in the rat: the effect of promoters and carcinogens in vivo and in vitro. Int. Rev. Cytol. 1986, 101, 125-173.
    • (1986) Int. Rev. Cytol , vol.101 , pp. 125-173
    • Moore, M.A.1    Kitagawa, T.2
  • 12
    • 25844461787 scopus 로고    scopus 로고
    • Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling
    • Nam, S. W., Park, J. Y., Ramasamy, A., Shevade, S. et al., Molecular changes from dysplastic nodule to hepatocellular carcinoma through gene expression profiling. Hepatology 2005, 42, 809-818.
    • (2005) Hepatology , vol.42 , pp. 809-818
    • Nam, S.W.1    Park, J.Y.2    Ramasamy, A.3    Shevade, S.4
  • 14
    • 0037097756 scopus 로고    scopus 로고
    • Phagocytosis of apoptotic cells by liver: A morphological study
    • Dini, L., Pagliara, P., Carla, E. C., Phagocytosis of apoptotic cells by liver: a morphological study. Microsc. Res. Tech. 2002, 57, 530-540.
    • (2002) Microsc. Res. Tech , vol.57 , pp. 530-540
    • Dini, L.1    Pagliara, P.2    Carla, E.C.3
  • 15
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi, P., Misteli, T., Bianchi, M. E., Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002, 418, 191-195.
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 16
    • 33845396978 scopus 로고    scopus 로고
    • New insights into the regulation of liver inflammation and oxidative stress
    • Ferre, N., Claria, J., New insights into the regulation of liver inflammation and oxidative stress. Mini Rev. Med. Chem. 2006, 6, 1321-1330.
    • (2006) Mini Rev. Med. Chem , vol.6 , pp. 1321-1330
    • Ferre, N.1    Claria, J.2
  • 17
    • 0036698294 scopus 로고    scopus 로고
    • Neutrophil-Kupffer cell interaction: A critical component of host defenses to systemic bacterial infections
    • Gregory, S. H., Wing, E. J., Neutrophil-Kupffer cell interaction: a critical component of host defenses to systemic bacterial infections. J. Leukoc. Biol. 2002, 72, 239-248.
    • (2002) J. Leukoc. Biol , vol.72 , pp. 239-248
    • Gregory, S.H.1    Wing, E.J.2
  • 18
    • 33845899370 scopus 로고    scopus 로고
    • Role of Kupffer cells in the pathogenesis of liver disease
    • Kolios, G., Valatas, V., Kouroumalis, E., Role of Kupffer cells in the pathogenesis of liver disease. World J. Gastroenterol. 2006, 12, 7413-7420.
    • (2006) World J. Gastroenterol , vol.12 , pp. 7413-7420
    • Kolios, G.1    Valatas, V.2    Kouroumalis, E.3
  • 20
    • 13844297437 scopus 로고    scopus 로고
    • Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: Studies on NADPH oxidase knockout mice
    • Teufelhofer, O., Parzefall, W., Kainzbauer, E., Ferk, F. et al., Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice. Carcinogenesis 2005, 26, 319-329.
    • (2005) Carcinogenesis , vol.26 , pp. 319-329
    • Teufelhofer, O.1    Parzefall, W.2    Kainzbauer, E.3    Ferk, F.4
  • 21
    • 0033939534 scopus 로고    scopus 로고
    • Grasl-Kraupp, B., Luebeck, G., Wagner, A., Low-Baselli, A. et al., Quantitative analysis of tumor initiation in rat liver: role of cell replication and cell death (apoptosis). Carcinogenesis 2000, 21, 1411-1421.
    • Grasl-Kraupp, B., Luebeck, G., Wagner, A., Low-Baselli, A. et al., Quantitative analysis of tumor initiation in rat liver: role of cell replication and cell death (apoptosis). Carcinogenesis 2000, 21, 1411-1421.
  • 22
    • 29744455074 scopus 로고    scopus 로고
    • Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis
    • Drucker, C., Parzefall, W., Teufelhofer, O., Grusch, M. et al., Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis. Carcinogenesis 2006, 27, 152-161.
    • (2006) Carcinogenesis , vol.27 , pp. 152-161
    • Drucker, C.1    Parzefall, W.2    Teufelhofer, O.3    Grusch, M.4
  • 23
    • 0028303879 scopus 로고
    • Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine
    • Weber, E., Bannasch, P., Dose and time dependence of the cellular phenotype in rat hepatic preneoplasia and neoplasia induced by single oral exposures to N-nitrosomorpholine. Carcinogenesis 1994, 15, 1219-1226.
    • (1994) Carcinogenesis , vol.15 , pp. 1219-1226
    • Weber, E.1    Bannasch, P.2
  • 24
    • 0037261429 scopus 로고    scopus 로고
    • Relevance of hepatic preneoplasia for human hepatocarcinogenesis
    • Su, Q., Bannasch, P., Relevance of hepatic preneoplasia for human hepatocarcinogenesis. Toxicol. Pathol. 2003, 31, 126-133.
    • (2003) Toxicol. Pathol , vol.31 , pp. 126-133
    • Su, Q.1    Bannasch, P.2
  • 25
    • 0035883904 scopus 로고    scopus 로고
    • Pathways of progression in hepatocarcinogenesis
    • Pitot, H. C., Pathways of progression in hepatocarcinogenesis. Lancet 2001, 358, 859-860.
    • (2001) Lancet , vol.358 , pp. 859-860
    • Pitot, H.C.1
  • 26
    • 0036653675 scopus 로고    scopus 로고
    • Concomitant determination of absolute values of cellular protein amounts, synthesis rates, and turnover rates by quantitative proteome profiling
    • Gerner, C., Vejda, S., Gelbmann, D., Bayer, E. et al., Concomitant determination of absolute values of cellular protein amounts, synthesis rates, and turnover rates by quantitative proteome profiling. Mol. Cell. Proteomics 2002, 1, 528-537.
    • (2002) Mol. Cell. Proteomics , vol.1 , pp. 528-537
    • Gerner, C.1    Vejda, S.2    Gelbmann, D.3    Bayer, E.4
  • 27
    • 33750576189 scopus 로고    scopus 로고
    • Divide and conquer: Rat liver tissue proteomics based on the analysis of purified constituents
    • Teufelhofer, O., Parzefall, W., Elbling, L., Kainzbauer, E. et al., Divide and conquer: rat liver tissue proteomics based on the analysis of purified constituents. Electrophoresis 2006, 27, 4112-4120.
    • (2006) Electrophoresis , vol.27 , pp. 4112-4120
    • Teufelhofer, O.1    Parzefall, W.2    Elbling, L.3    Kainzbauer, E.4
  • 28
    • 2442553728 scopus 로고    scopus 로고
    • Towards a standardized human proteome database: Quantitative proteome profiling of living cells
    • Traxler, E., Bayer, E., Stockl, J., Mohr, T. et al., Towards a standardized human proteome database: quantitative proteome profiling of living cells. Proteomics 2004, 4, 1314-1323.
    • (2004) Proteomics , vol.4 , pp. 1314-1323
    • Traxler, E.1    Bayer, E.2    Stockl, J.3    Mohr, T.4
  • 29
    • 0023113248 scopus 로고
    • Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan
    • Friedman, S. L., Roll, F. J., Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan. Anal. Biochem. 1987, 161, 207-218.
    • (1987) Anal. Biochem , vol.161 , pp. 207-218
    • Friedman, S.L.1    Roll, F.J.2
  • 30
    • 0022261834 scopus 로고
    • Functional and morphological characterization of cultures of Kupffer cells and liver endothelial cells prepared by means of density separation in Percoll, and selective substrate adherence
    • Smedsrod, B., Pertoft, H., Eggertsen, G., Sundstrom, C., Functional and morphological characterization of cultures of Kupffer cells and liver endothelial cells prepared by means of density separation in Percoll, and selective substrate adherence. Cell Tissue Res. 1985, 241, 639-649.
    • (1985) Cell Tissue Res , vol.241 , pp. 639-649
    • Smedsrod, B.1    Pertoft, H.2    Eggertsen, G.3    Sundstrom, C.4
  • 31
    • 0035093678 scopus 로고    scopus 로고
    • Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes
    • Parzefall, W., Berger, W., Kainzbauer, E., Teufelhofer, O. et al., Peroxisome proliferators do not increase DNA synthesis in purified rat hepatocytes. Carcinogenesis 2001, 22, 519-523.
    • (2001) Carcinogenesis , vol.22 , pp. 519-523
    • Parzefall, W.1    Berger, W.2    Kainzbauer, E.3    Teufelhofer, O.4
  • 32
    • 33745968529 scopus 로고    scopus 로고
    • Knowledge-based proteome profiling: Considering identified proteins to evaluate separation efficiency by 2-D PAGE
    • Gundacker, N., Bayer, E., Traxler, E., Zwickl, H. et al., Knowledge-based proteome profiling: considering identified proteins to evaluate separation efficiency by 2-D PAGE. Electrophoresis 2006, 27, 2712-2721.
    • (2006) Electrophoresis , vol.27 , pp. 2712-2721
    • Gundacker, N.1    Bayer, E.2    Traxler, E.3    Zwickl, H.4
  • 33
    • 0035346790 scopus 로고    scopus 로고
    • A comparison between Sypro Ruby and ruthenium II tris (bathophenanthroline disulfonate) as fluorescent stains for protein detection in gels
    • Rabilloud, T., Strub, J. M., Luche, S., van Dorsselaer, A., Lunardi, J., A comparison between Sypro Ruby and ruthenium II tris (bathophenanthroline disulfonate) as fluorescent stains for protein detection in gels. Proteomics 2001, 1, 699-704.
    • (2001) Proteomics , vol.1 , pp. 699-704
    • Rabilloud, T.1    Strub, J.M.2    Luche, S.3    van Dorsselaer, A.4    Lunardi, J.5
  • 34
    • 23144465869 scopus 로고    scopus 로고
    • A novel technique to specifically analyze the secretome of cells and tissues
    • Zwickl, H., Traxler, E., Staettner, S., Parzefall, W. et al., A novel technique to specifically analyze the secretome of cells and tissues. Electrophoresis 2005, 26, 2779-2785.
    • (2005) Electrophoresis , vol.26 , pp. 2779-2785
    • Zwickl, H.1    Traxler, E.2    Staettner, S.3    Parzefall, W.4
  • 35
    • 18844458022 scopus 로고    scopus 로고
    • Use of two-dimensional gel electrophoresis in predictive toxicology: Identification of potential early protein biomarkers in chemically induced hepatocarcinogenesis
    • Fella, K., Gluckmann, M., Hellmann, J., Karas, M. et al., Use of two-dimensional gel electrophoresis in predictive toxicology: identification of potential early protein biomarkers in chemically induced hepatocarcinogenesis. Proteomics 2005, 5, 1914-1927.
    • (2005) Proteomics , vol.5 , pp. 1914-1927
    • Fella, K.1    Gluckmann, M.2    Hellmann, J.3    Karas, M.4
  • 36
    • 33644864832 scopus 로고    scopus 로고
    • Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: Toxicity differentiation in hepatotoxicants
    • Yamamoto, T., Kikkawa, R., Yamada, H., Horii, I., Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: toxicity differentiation in hepatotoxicants. J. Toxicol. Sci. 2006, 31, 49-60.
    • (2006) J. Toxicol. Sci , vol.31 , pp. 49-60
    • Yamamoto, T.1    Kikkawa, R.2    Yamada, H.3    Horii, I.4
  • 37
    • 33645753484 scopus 로고    scopus 로고
    • Secretory protein enrichment and analysis: An optimized approach applied on cancer cell lines using 2D LC-MS/MS
    • Mbeunkui, F., Fodstad, O., Pannell, L. K., Secretory protein enrichment and analysis: an optimized approach applied on cancer cell lines using 2D LC-MS/MS. J. Proteome Res. 2006, 5, 899-906.
    • (2006) J. Proteome Res , vol.5 , pp. 899-906
    • Mbeunkui, F.1    Fodstad, O.2    Pannell, L.K.3
  • 39
    • 32444433202 scopus 로고    scopus 로고
    • Free radicals, metals and antioxidants in oxidative stress-induced cancer
    • Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., Mazur, M., Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 2006, 160, 1-40.
    • (2006) Chem. Biol. Interact , vol.160 , pp. 1-40
    • Valko, M.1    Rhodes, C.J.2    Moncol, J.3    Izakovic, M.4    Mazur, M.5
  • 40
    • 19444375216 scopus 로고    scopus 로고
    • Peroxiredoxins: A historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling
    • Rhee, S. G., Chae, H. Z., Kim, K., Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic. Biol. Med. 2005, 38, 1543-1552.
    • (2005) Free Radic. Biol. Med , vol.38 , pp. 1543-1552
    • Rhee, S.G.1    Chae, H.Z.2    Kim, K.3
  • 41
    • 17644395645 scopus 로고    scopus 로고
    • Thioredoxin and its related molecules: Update 2005
    • Nakamura, H., Thioredoxin and its related molecules: update 2005. Antioxid. Redox Signal. 2005, 7, 823-828.
    • (2005) Antioxid. Redox Signal , vol.7 , pp. 823-828
    • Nakamura, H.1
  • 42
    • 0035584857 scopus 로고    scopus 로고
    • Reactive oxygen species, antioxidants, and the mammalian thioredoxin system
    • Nordberg, J., Arner, E. S., Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol. Med. 2001, 31, 1287-1312.
    • (2001) Free Radic. Biol. Med , vol.31 , pp. 1287-1312
    • Nordberg, J.1    Arner, E.S.2
  • 43
    • 0042090407 scopus 로고    scopus 로고
    • The differential expression of cytosolic carbonic anhydrase in human hepatocellular carcinoma
    • Kuo, W. H., Chiang, W. L., Yang, S. F., Yeh, K. T. et al., The differential expression of cytosolic carbonic anhydrase in human hepatocellular carcinoma. Life Sci. 2003, 73, 2211-2223.
    • (2003) Life Sci , vol.73 , pp. 2211-2223
    • Kuo, W.H.1    Chiang, W.L.2    Yang, S.F.3    Yeh, K.T.4
  • 44
    • 0345003848 scopus 로고    scopus 로고
    • R.ais.anen, S. R., Lehenkari, P., Tasanen, M., Rahkila, P. et al., Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis. FASEB J. 1999, 13, 513-522.
    • R.ais.anen, S. R., Lehenkari, P., Tasanen, M., Rahkila, P. et al., Carbonic anhydrase III protects cells from hydrogen peroxide-induced apoptosis. FASEB J. 1999, 13, 513-522.
  • 45
    • 0032538130 scopus 로고    scopus 로고
    • Hydroxyl radical formation via ironmediated Fenton chemistry is inhibited by methylated catechols
    • Nappi, A. J., Vass, E., Hydroxyl radical formation via ironmediated Fenton chemistry is inhibited by methylated catechols. Biochim. Biophys. Acta 1998, 1425, 159-167.
    • (1998) Biochim. Biophys. Acta , vol.1425 , pp. 159-167
    • Nappi, A.J.1    Vass, E.2
  • 46
    • 27844486110 scopus 로고    scopus 로고
    • Modulation of xenobiotic metabolising enzymes by anticarcinogens - focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis
    • Pool-Zobel, B., Veeriah, S., Bohmer, F. D., Modulation of xenobiotic metabolising enzymes by anticarcinogens - focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis. Mutat. Res. 2005, 591, 74-92.
    • (2005) Mutat. Res , vol.591 , pp. 74-92
    • Pool-Zobel, B.1    Veeriah, S.2    Bohmer, F.D.3
  • 47
    • 0032955185 scopus 로고    scopus 로고
    • Glutathione S-transferases - a review
    • Salinas, A. E., Wong, M. G., Glutathione S-transferases - a review. Curr. Med. Chem. 1999, 6, 279-309.
    • (1999) Curr. Med. Chem , vol.6 , pp. 279-309
    • Salinas, A.E.1    Wong, M.G.2
  • 48
    • 3042802690 scopus 로고    scopus 로고
    • Glutathione: An overview of biosynthesis and modulation
    • Anderson, M. E., Glutathione: an overview of biosynthesis and modulation. Chem. Biol. Interact. 1998, 111- 112, 1-14.
    • (1998) Chem. Biol. Interact , vol.111-112 , pp. 1-14
    • Anderson, M.E.1
  • 49
    • 14844313300 scopus 로고    scopus 로고
    • Physiological and pathological aspects of GSH metabolism
    • Njalsson, R., Norgren, S., Physiological and pathological aspects of GSH metabolism. Acta Paediatr. 2005, 94, 132-137.
    • (2005) Acta Paediatr , vol.94 , pp. 132-137
    • Njalsson, R.1    Norgren, S.2
  • 50
    • 33751203833 scopus 로고    scopus 로고
    • Heat shock proteins 27 and 70: Anti-apoptotic proteins with tumorigenic properties
    • Garrido, C., Brunet, M., Didelot, C., Zermati, Y. et al., Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties. Cell Cycle 2006, 5, 2592-2601.
    • (2006) Cell Cycle , vol.5 , pp. 2592-2601
    • Garrido, C.1    Brunet, M.2    Didelot, C.3    Zermati, Y.4
  • 51
  • 52
    • 0037082108 scopus 로고    scopus 로고
    • Proteasome-dependent turnover of protein disulfide isomerase in oxidatively stressed cells
    • Grune, T., Reinheckel, T., Li, R., North, J. A., Davies, K. J., Proteasome-dependent turnover of protein disulfide isomerase in oxidatively stressed cells. Arch. Biochem. Biophys. 2002, 397, 407-413.
    • (2002) Arch. Biochem. Biophys , vol.397 , pp. 407-413
    • Grune, T.1    Reinheckel, T.2    Li, R.3    North, J.A.4    Davies, K.J.5
  • 53
    • 33746275653 scopus 로고    scopus 로고
    • Proteomic analysis of ischemia-reperfusion injury upon human liver transplantation reveals the protective role of IQGAP1
    • Emadali, A., Muscatelli-Groux, B., Delom, F., Jenna, S. et al., Proteomic analysis of ischemia-reperfusion injury upon human liver transplantation reveals the protective role of IQGAP1. Mol. Cell. Proteomics 2006, 5, 1300-1313.
    • (2006) Mol. Cell. Proteomics , vol.5 , pp. 1300-1313
    • Emadali, A.1    Muscatelli-Groux, B.2    Delom, F.3    Jenna, S.4
  • 54
    • 0037648896 scopus 로고    scopus 로고
    • Molecular targeting therapy of cancer: Drug resistance, apoptosis and survival signal
    • Tsuruo, T., Naito, M., Tomida, A., Fujita, N. et al., Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal. Cancer Sci. 2003, 94, 15-21.
    • (2003) Cancer Sci , vol.94 , pp. 15-21
    • Tsuruo, T.1    Naito, M.2    Tomida, A.3    Fujita, N.4
  • 55
    • 29644440061 scopus 로고    scopus 로고
    • ERp29 is an essential endoplasmic reticulum factor regulating secretion of thyroglobulin
    • Baryshev, M., Sargsyan, E., Mkrtchian, S., ERp29 is an essential endoplasmic reticulum factor regulating secretion of thyroglobulin. Biochem. Biophys. Res. Commun. 2006, 340, 617-624.
    • (2006) Biochem. Biophys. Res. Commun , vol.340 , pp. 617-624
    • Baryshev, M.1    Sargsyan, E.2    Mkrtchian, S.3
  • 56
    • 33749451013 scopus 로고    scopus 로고
    • Expression of ERp29, an endoplasmic reticulum secretion factor in basal-cell carcinoma
    • Cheretis, C., Dietrich, F., Chatzistamou, I., Politi, K. et al., Expression of ERp29, an endoplasmic reticulum secretion factor in basal-cell carcinoma. Am. J. Dermatopathol. 2006, 28, 410-412.
    • (2006) Am. J. Dermatopathol , vol.28 , pp. 410-412
    • Cheretis, C.1    Dietrich, F.2    Chatzistamou, I.3    Politi, K.4
  • 57
    • 0025228036 scopus 로고
    • Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6
    • Castell, J. V., Gomez-Lechon, M. J., David, M., Fabra, R. et al., Acute-phase response of human hepatocytes: regulation of acute-phase protein synthesis by interleukin-6. Hepatology 1990, 12, 1179-1186.
    • (1990) Hepatology , vol.12 , pp. 1179-1186
    • Castell, J.V.1    Gomez-Lechon, M.J.2    David, M.3    Fabra, R.4
  • 59
    • 0030823183 scopus 로고    scopus 로고
    • IL-6 and APPs: Antiinflammatory and immunosuppressive mediators
    • Tilg, H., Dinarello, C. A., Mier, J. W., IL-6 and APPs: antiinflammatory and immunosuppressive mediators. Immunol. Today 1997, 18, 428-432.
    • (1997) Immunol. Today , vol.18 , pp. 428-432
    • Tilg, H.1    Dinarello, C.A.2    Mier, J.W.3
  • 61
    • 20644465187 scopus 로고    scopus 로고
    • Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent
    • Camargo, C. A., Jr., Madden, J. F., Gao, W., Selvan, R. S., Clavien, P. A., Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. Hepatology 1997, 26, 1513-1520.
    • (1997) Hepatology , vol.26 , pp. 1513-1520
    • Camargo Jr., C.A.1    Madden, J.F.2    Gao, W.3    Selvan, R.S.4    Clavien, P.A.5
  • 62
    • 5044232017 scopus 로고    scopus 로고
    • Liver regeneration: From myth to mechanism
    • Taub, R., Liver regeneration: from myth to mechanism. Nat. Rev. Mol. Cell Biol. 2004, 5, 836-847.
    • (2004) Nat. Rev. Mol. Cell Biol , vol.5 , pp. 836-847
    • Taub, R.1
  • 63
    • 15444374348 scopus 로고    scopus 로고
    • The anti-inflammatory effect of exercise
    • Petersen, A. M., Pedersen, B. K., The anti-inflammatory effect of exercise. J. Appl. Physiol. 2005, 98, 1154-1162.
    • (2005) J. Appl. Physiol , vol.98 , pp. 1154-1162
    • Petersen, A.M.1    Pedersen, B.K.2
  • 64
    • 33746543666 scopus 로고    scopus 로고
    • Involvement of the innate immune system in liver regeneration and injury
    • Fausto, N., Involvement of the innate immune system in liver regeneration and injury. J. Hepatol. 2006, 45, 347-349.
    • (2006) J. Hepatol , vol.45 , pp. 347-349
    • Fausto, N.1
  • 66
    • 19844373824 scopus 로고    scopus 로고
    • Soluble mediators of inflammation during tumor development
    • Robinson, S. C., Coussens, L. M., Soluble mediators of inflammation during tumor development. Adv. Cancer Res. 2005, 93, 159-187.
    • (2005) Adv. Cancer Res , vol.93 , pp. 159-187
    • Robinson, S.C.1    Coussens, L.M.2
  • 67
    • 33751543926 scopus 로고    scopus 로고
    • Modeling regulatory mechanisms in IL-6 signal transduction in hepatocytes
    • Singh, A., Jayaraman, A., Hahn, J., Modeling regulatory mechanisms in IL-6 signal transduction in hepatocytes. Biotechnol. Bioeng. 2006, 95, 850-862.
    • (2006) Biotechnol. Bioeng , vol.95 , pp. 850-862
    • Singh, A.1    Jayaraman, A.2    Hahn, J.3
  • 68
    • 0037408080 scopus 로고    scopus 로고
    • Factors that affect albumin concentration in dialysis patients and their relationship to vascular disease
    • Kaysen, G. A., Don, B. R., Factors that affect albumin concentration in dialysis patients and their relationship to vascular disease. Kidney Int. Suppl. 2003, S94-S97.
    • (2003) Kidney Int. Suppl
    • Kaysen, G.A.1    Don, B.R.2
  • 69
    • 33750984761 scopus 로고    scopus 로고
    • The role of cystatins in cells of the immune system
    • Kopitar-Jerala, N., The role of cystatins in cells of the immune system. FEBS Lett. 2006, 580, 6295-6301.
    • (2006) FEBS Lett , vol.580 , pp. 6295-6301
    • Kopitar-Jerala, N.1
  • 70
    • 0035914268 scopus 로고    scopus 로고
    • Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: Relation to prognosis
    • Kos, J., Sekirnik, A., Kopitar, G., Cimerman, N. et al., Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis. Br. J. Cancer 2001, 85, 1193-1200.
    • (2001) Br. J. Cancer , vol.85 , pp. 1193-1200
    • Kos, J.1    Sekirnik, A.2    Kopitar, G.3    Cimerman, N.4
  • 72
    • 0036067659 scopus 로고    scopus 로고
    • Toll receptors, CD14, and macrophage activation and deactivation by LPS
    • Dobrovolskaia, M. A., Vogel, S. N., Toll receptors, CD14, and macrophage activation and deactivation by LPS. Microbes Infect. 2002, 4, 903-914.
    • (2002) Microbes Infect , vol.4 , pp. 903-914
    • Dobrovolskaia, M.A.1    Vogel, S.N.2
  • 73
    • 0037763721 scopus 로고    scopus 로고
    • Regulatory mechanisms controlling gene expression mediated by the antioxidant response element
    • Nguyen, T., Sherratt, P. J., Pickett, C. B., Regulatory mechanisms controlling gene expression mediated by the antioxidant response element. Annu. Rev. Pharmacol. Toxicol. 2003, 43, 233-260.
    • (2003) Annu. Rev. Pharmacol. Toxicol , vol.43 , pp. 233-260
    • Nguyen, T.1    Sherratt, P.J.2    Pickett, C.B.3
  • 74
    • 33748480423 scopus 로고    scopus 로고
    • Carbon monoxide: The bad and the good side of the coin, from neuronal death to anti-inflammatory activity
    • Mannaioni, P. F., Vannacci, A., Masini, E., Carbon monoxide: the bad and the good side of the coin, from neuronal death to anti-inflammatory activity. Inflamm. Res. 2006, 55, 261-273.
    • (2006) Inflamm. Res , vol.55 , pp. 261-273
    • Mannaioni, P.F.1    Vannacci, A.2    Masini, E.3
  • 75
    • 33745600548 scopus 로고    scopus 로고
    • Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats
    • Hirsch, J., Hansen, K. C., Choi, S., Noh, J. et al., Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats. Mol. Cell. Proteomics 2006, 5, 979-986.
    • (2006) Mol. Cell. Proteomics , vol.5 , pp. 979-986
    • Hirsch, J.1    Hansen, K.C.2    Choi, S.3    Noh, J.4
  • 76
    • 29144501207 scopus 로고    scopus 로고
    • The interferon response circuit: Induction and suppression by pathogenic viruses
    • Haller, O., Kochs, G., Weber, F., The interferon response circuit: induction and suppression by pathogenic viruses. Virology 2006, 344, 119-130.
    • (2006) Virology , vol.344 , pp. 119-130
    • Haller, O.1    Kochs, G.2    Weber, F.3
  • 77
    • 0034652810 scopus 로고    scopus 로고
    • TNFalpha and MIP-2: Role in particle-induced inflammation and regulation by oxidative stress
    • Driscoll, K. E., TNFalpha and MIP-2: role in particle-induced inflammation and regulation by oxidative stress. Toxicol. Lett. 2000, 112-113, 177-183.
    • (2000) Toxicol. Lett , vol.112-113 , pp. 177-183
    • Driscoll, K.E.1
  • 79
    • 0024848284 scopus 로고
    • Macrophage inflammatory proteins 1 and 2: Members of a novel superfamily of cytokines
    • Wolpe, S. D., Cerami, A., Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines. FASEB J. 1989, 3, 2565-2573.
    • (1989) FASEB J , vol.3 , pp. 2565-2573
    • Wolpe, S.D.1    Cerami, A.2
  • 80
  • 81
    • 0035431354 scopus 로고    scopus 로고
    • Protease-induced leukocyte chemotaxis and activation: Roles in host defense and inflammation
    • Tani, K., Ogushi, F., Shimizu, T., Sone, S., Protease-induced leukocyte chemotaxis and activation: roles in host defense and inflammation. J. Med. Invest. 2001, 48, 133-141.
    • (2001) J. Med. Invest , vol.48 , pp. 133-141
    • Tani, K.1    Ogushi, F.2    Shimizu, T.3    Sone, S.4
  • 82
    • 33745310690 scopus 로고    scopus 로고
    • a structural perspective on human disease
    • Intracellular TLR signaling
    • Lasker, M. V., Nair, S. K., Intracellular TLR signaling: a structural perspective on human disease. J. Immunol. 2006, 177, 11-16.
    • (2006) J. Immunol , vol.177 , pp. 11-16
    • Lasker, M.V.1    Nair, S.K.2
  • 83
    • 33646347356 scopus 로고    scopus 로고
    • Toll-like receptor signaling in the liver
    • Schwabe, R. F., Seki, E., Brenner, D. A., Toll-like receptor signaling in the liver. Gastroenterology 2006, 130, 1886-1900.
    • (2006) Gastroenterology , vol.130 , pp. 1886-1900
    • Schwabe, R.F.1    Seki, E.2    Brenner, D.A.3
  • 84
    • 0036074141 scopus 로고    scopus 로고
    • Lipopolysaccharides in liver injury: Molecular mechanisms of Kupffer cell activation
    • Su, G. L., Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation. Am. J. Physiol. Gastrointest. Liver Physiol. 2002, 283, G256-G265.
    • (2002) Am. J. Physiol. Gastrointest. Liver Physiol , vol.283
    • Su, G.L.1
  • 85
    • 0035038751 scopus 로고    scopus 로고
    • RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays
    • Bulera, S. J., Eddy, S. M., Ferguson, E., Jatkoe, T. A. et al., RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. Hepatology 2001, 33, 1239-1258.
    • (2001) Hepatology , vol.33 , pp. 1239-1258
    • Bulera, S.J.1    Eddy, S.M.2    Ferguson, E.3    Jatkoe, T.A.4
  • 86
    • 31144440448 scopus 로고    scopus 로고
    • Molecular basis for adaptive responses during chemically induced hepatotoxicity
    • Burcham, P. C., Molecular basis for adaptive responses during chemically induced hepatotoxicity. Toxicol. Sci. 2006, 89, 349-351.
    • (2006) Toxicol. Sci , vol.89 , pp. 349-351
    • Burcham, P.C.1
  • 87
    • 33745065775 scopus 로고    scopus 로고
    • Proteomic analysis of liver tissues subjected to early ischemia/ reperfusion injury during human orthotopic liver transplantation
    • Vascotto, C., Cesaratto, L., D'Ambrosio, C., Scaloni, A. et al., Proteomic analysis of liver tissues subjected to early ischemia/ reperfusion injury during human orthotopic liver transplantation. Proteomics 2006, 6, 3455-3465.
    • (2006) Proteomics , vol.6 , pp. 3455-3465
    • Vascotto, C.1    Cesaratto, L.2    D'Ambrosio, C.3    Scaloni, A.4
  • 88
    • 0032425945 scopus 로고    scopus 로고
    • Probing the mechanism of the carcinogenic activation of N-nitrosodiethanolamine with deuterium isotope effects: In vivo induction of DNA single-strand breaks and related in vitro assays
    • Loeppky, R. N., Fuchs, A., Janzowski, C., Humberd, C. et al., Probing the mechanism of the carcinogenic activation of N-nitrosodiethanolamine with deuterium isotope effects: in vivo induction of DNA single-strand breaks and related in vitro assays. Chem. Res. Toxicol. 1998, 11, 1556-1566.
    • (1998) Chem. Res. Toxicol , vol.11 , pp. 1556-1566
    • Loeppky, R.N.1    Fuchs, A.2    Janzowski, C.3    Humberd, C.4
  • 89
    • 33745489431 scopus 로고    scopus 로고
    • Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis
    • Kawanishi, S., Hiraku, Y., Pinlaor, S., Ma, N., Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol. Chem. 2006, 387, 365-372.
    • (2006) Biol. Chem , vol.387 , pp. 365-372
    • Kawanishi, S.1    Hiraku, Y.2    Pinlaor, S.3    Ma, N.4
  • 90
    • 0028051314 scopus 로고
    • Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver
    • Grasl-Kraupp, B., Bursch, W., Ruttkay-Nedecky, B., Wagner, A. et al., Food restriction eliminates preneoplastic cells through apoptosis and antagonizes carcinogenesis in rat liver. Proc. Natl. Acad. Sci. USA 1994, 91, 9995-9999.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9995-9999
    • Grasl-Kraupp, B.1    Bursch, W.2    Ruttkay-Nedecky, B.3    Wagner, A.4
  • 91
    • 0030915471 scopus 로고    scopus 로고
    • Inherent increase of apoptosis in liver tumors: Implications for carcinogenesis and tumor regression
    • Grasl-Kraupp, B., Ruttkay-Nedecky, B., M. ullauer, L., Taper, H. et al., Inherent increase of apoptosis in liver tumors: implications for carcinogenesis and tumor regression. Hepatology 1997, 25, 906-912.
    • (1997) Hepatology , vol.25 , pp. 906-912
    • Grasl-Kraupp, B.1    Ruttkay-Nedecky, B.M.2    ullauer, L.3    Taper, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.