Huntingtin N-Terminal Monomeric and Multimeric Structures Destabilized by Covalent Modification of Heteroatomic Residues

Biochemistry

Volumn 54, Issue 28, 2015, Pages 4285-4296

  Arndt, James R ^a   Kondalaji, Samaneh Ghassabi ^a   Maurer, Megan M ^a   Parker, Arlo ^a   Legleiter, Justin ^a   Valentine, Stephen J ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSOCIATION REACTIONS; IONS; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MONOMERS; OLIGOMERS; PROTEINS; SPECTROMETRY;

COVALENT MODIFICATIONS; DIETHYLPYROCARBONATE; HUNTINGTON'S DISEASE; ION MOBILITY SPECTROMETRY; MOLECULAR DYNAMICS SIMULATIONS; OLIGOMER FORMATIONS; OLIGOMERIC STRUCTURE; STRUCTURAL CHARACTERIZATION;

DIMERS;

DIETHYL PYROCARBONATE; HUNTINGTIN; MONOMER; POLYMER; HTT PROTEIN, HUMAN; LYSINE; NERVE PROTEIN; PEPTIDE; THREONINE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; ION MOBILITY SPECTROMETRY; MASS SPECTROMETRY; MOLECULAR DYNAMICS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; CHEMISTRY; HUMAN; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY;

DIETHYL PYROCARBONATE; HUMANS; LYSINE; MASS SPECTROMETRY; MOLECULAR DYNAMICS SIMULATION; NERVE TISSUE PROTEINS; PEPTIDES; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; THREONINE;

EID: 84937576786     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00478     Document Type: Article

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