The Predicted Structure of the Headpiece of the Huntingtin Protein and Its Implications on Huntingtin Aggregation

Journal of Molecular Biology

Volumn 388, Issue 5, 2009, Pages 919-927

  Kelley, Nicholas W ^a   Huang, Xuhui ^b   Tam, Stephen ^a   Spiess, Christoph ^a   Frydman, Judith ^a   Pande, Vijay S ^a  

^a STANFORD UNIVERSITY   (United States)

^b Stanford University   (United States)

Author keywords

Folding@Home; Huntington's Disease; Molecular Dynamics; N17Htt; Simulated Tempering

Indexed keywords

HUNTINGTIN; HUNTINGTIN N17; POLYGLUTAMINE; RNA; SINGLE STRANDED DNA BINDING PROTEIN; SOLVENT; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; COMPUTER SIMULATION; DIMERIZATION; EXPERIMENTAL STUDY; HYDROPHOBICITY; MOLECULAR DYNAMICS; PREDICTION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RNA TRANSLATION; SAMPLING; STRUCTURAL PROTEOMICS; STRUCTURE ANALYSIS; THERMODYNAMICS;

EID: 67349278762     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.01.032     Document Type: Article

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