-
1
-
-
0035196734
-
Regulation of transforming growth factor-β signaling
-
Zhu, H. J., and Burgess, A. W. (2001) Regulation of transforming growth factor-β signaling. Mol. Cell Biol. Res. Commun. 4, 321-330.
-
(2001)
Mol. Cell Biol. Res. Commun.
, vol.4
, pp. 321-330
-
-
Zhu, H.J.1
Burgess, A.W.2
-
2
-
-
55449107515
-
Regulation of TGF-β family signaling by E3 ubiquitin ligases
-
Inoue, Y., and Imamura, T. (2008) Regulation of TGF-β family signaling by E3 ubiquitin ligases. Cancer Sci. 99, 2107-2112.
-
(2008)
Cancer Sci.
, vol.99
, pp. 2107-2112
-
-
Inoue, Y.1
Imamura, T.2
-
3
-
-
70350231912
-
Gain or loss of TGF-β signaling in mammary carcinoma cells can promote metastasis
-
Bierie, B., and Moses, H. L. (2009) Gain or loss of TGF-β signaling in mammary carcinoma cells can promote metastasis. Cell Cycle 8, 3319-3327.
-
(2009)
Cell Cycle
, vol.8
, pp. 3319-3327
-
-
Bierie, B.1
Moses, H.L.2
-
4
-
-
70450187617
-
The regulation of TGF-βsignal transduction
-
Moustakas, A., and Heldin, C. H. (2009) The regulation of TGF-βsignal transduction. Development 136, 3699-3714.
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.H.2
-
5
-
-
84880176268
-
Transforming growth factor- βsignalling: Role and consequences of Smad linker region phosphorylation
-
Kamato, D., Burch, M. L., Piva, T. J., Rezaei, H. B., Rostam, M. A., Xu, S., Zheng, W., Little, P. J., and Osman, N. (2013) Transforming growth factor- βsignalling: role and consequences of Smad linker region phosphorylation. Cell. Signal. 25, 2017-2024.
-
(2013)
Cell. Signal.
, vol.25
, pp. 2017-2024
-
-
Kamato, D.1
Burch, M.L.2
Piva, T.J.3
Rezaei, H.B.4
Rostam, M.A.5
Xu, S.6
Zheng, W.7
Little, P.J.8
Osman, N.9
-
6
-
-
0030069171
-
Gastric lesions in transforming growth factor β-1 heterozygous mice
-
Boivin, G. P., Molina, J. R., Ormsby, I., Stemmermann, G., and Doetschman, T. (1996) Gastric lesions in transforming growth factor β-1 heterozygous mice. Lab. Invest. 74, 513-518.
-
(1996)
Lab. Invest.
, vol.74
, pp. 513-518
-
-
Boivin, G.P.1
Molina, J.R.2
Ormsby, I.3
Stemmermann, G.4
Doetschman, T.5
-
7
-
-
0034611611
-
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
-
Xu, X., Brodie, S. G., Yang, X., Im, Y. H., Parks, W. T., Chen, L., Zhou, Y. X., Weinstein, M., Kim, S. J., and Deng, C. X. (2000) Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. Oncogene 19, 1868-1874.
-
(2000)
Oncogene
, vol.19
, pp. 1868-1874
-
-
Xu, X.1
Brodie, S.G.2
Yang, X.3
Im, Y.H.4
Parks, W.T.5
Chen, L.6
Zhou, Y.X.7
Weinstein, M.8
Kim, S.J.9
Deng, C.X.10
-
8
-
-
0031441041
-
Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor- receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7, 12-dimethylbenz-[a]-anthracene
-
Böttinger, E. P., Jakubczak, J. L., Haines, D. C., Bagnall, K., and Wakefield, L. M. (1997) Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor- receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7, 12-dimethylbenz-[a]-anthracene. Cancer Res. 57, 5564-5570.
-
(1997)
Cancer Res.
, vol.57
, pp. 5564-5570
-
-
Böttinger, E.P.1
Jakubczak, J.L.2
Haines, D.C.3
Bagnall, K.4
Wakefield, L.M.5
-
9
-
-
32444432368
-
In vivo disruption of TGF-β signaling by Smad7 leads to premalignant ductal lesions in the pancreas
-
Kuang, C., Xiao, Y., Liu, X., Stringfield, T. M., Zhang, S., Wang, Z., and Chen, Y. (2006) In vivo disruption of TGF-β signaling by Smad7 leads to premalignant ductal lesions in the pancreas. Proc. Natl. Acad. Sci. U.S.A. 103, 1858-1863.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 1858-1863
-
-
Kuang, C.1
Xiao, Y.2
Liu, X.3
Stringfield, T.M.4
Zhang, S.5
Wang, Z.6
Chen, Y.7
-
10
-
-
23844445451
-
Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
-
Jenkins, B. J., Grail, D., Nheu, T., Najdovska, M., Wang, B., Waring, P., Inglese, M., McLoughlin, R. M., Jones, S. A., Topley, N., Baumann, H., Judd, L. M., Giraud, A. S., Boussioutas, A., Zhu, H. J., and Ernst, M. (2005) Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling. Nat. Med. 11, 845-852.
-
(2005)
Nat. Med.
, vol.11
, pp. 845-852
-
-
Jenkins, B.J.1
Grail, D.2
Nheu, T.3
Najdovska, M.4
Wang, B.5
Waring, P.6
Inglese, M.7
McLoughlin, R.M.8
Jones, S.A.9
Topley, N.10
Baumann, H.11
Judd, L.M.12
Giraud, A.S.13
Boussioutas, A.14
Zhu, H.J.15
Ernst, M.16
-
11
-
-
0037979081
-
Heart and liver defects and reduced transforming growth factor -2 sensitivity in transforming growth factor β type III receptordeficient embryos
-
Stenvers, K. L., Tursky, M. L., Harder, K. W., Kountouri, N., Amatayakul- Chantler, S., Grail, D., Small, C., Weinberg, R. A., Sizeland, A. M., and Zhu, H. J. (2003) Heart and liver defects and reduced transforming growth factor -2 sensitivity in transforming growth factor β type III receptordeficient embryos. Mol. Cell. Biol. 23, 4371-4385.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 4371-4385
-
-
Stenvers, K.L.1
Tursky, M.L.2
Harder, K.W.3
Kountouri, N.4
Amatayakul- Chantler, S.5
Grail, D.6
Small, C.7
Weinberg, R.A.8
Sizeland, A.M.9
Zhu, H.J.10
-
12
-
-
0034654497
-
Controlling TGF-β signaling
-
Massagué, J., and Chen, Y. G. (2000) Controlling TGF-β signaling. Genes Dev. 14, 627-644.
-
(2000)
Genes Dev.
, vol.14
, pp. 627-644
-
-
Massagué, J.1
Chen, Y.G.2
-
13
-
-
0034695511
-
Regulation of Smad activity
-
Wrana, J. L. (2000) Regulation of Smad activity. Cell 100, 189-192.
-
(2000)
Cell
, vol.100
, pp. 189-192
-
-
Wrana, J.L.1
-
14
-
-
0023940794
-
Latent high molecular weight complex of transforming growth factor β 1. Purification from human platelets and structural characterization
-
Miyazono, K., Hellman, U., Wernstedt, C., and Heldin, C. H. (1988) Latent high molecular weight complex of transforming growth factor β 1. Purification from human platelets and structural characterization. J. Biol. Chem. 263, 6407-6415.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 6407-6415
-
-
Miyazono, K.1
Hellman, U.2
Wernstedt, C.3
Heldin, C.H.4
-
15
-
-
0024372267
-
Recombinant TGF- β 1 is synthesized as a two-component latent complex that shares some structural features with the native platelet latent TGF-, β1 complex
-
Wakefield, L. M., Smith, D. M., Broz, S., Jackson, M., Levinson, A. D., and Sporn, M. B. (1989) Recombinant TGF- β 1 is synthesized as a two-component latent complex that shares some structural features with the native platelet latent TGF- β1 complex. Growth Factors 1, 203-218.
-
(1989)
Growth Factors
, vol.1
, pp. 203-218
-
-
Wakefield, L.M.1
Smith, D.M.2
Broz, S.3
Jackson, M.4
Levinson, A.D.5
Sporn, M.B.6
-
16
-
-
0025353729
-
Negative regulationof transforming growth factor-, β by the proteoglycan decorin
-
Yamaguchi, Y., Mann, D. M., and Ruoslahti, E. (1990) Negative regulationof transforming growth factor- β by the proteoglycan decorin. Nature 346, 281-284.
-
(1990)
Nature
, vol.346
, pp. 281-284
-
-
Yamaguchi, Y.1
Mann, D.M.2
Ruoslahti, E.3
-
17
-
-
0026676859
-
Natural inhibitor of transforming growth factor- β protects against scarring in experimental kidney disease
-
Border, W. A., Noble, N. A., Yamamoto, T., Harper, J. R., Yamaguchi, Y., Pierschbacher, M. D., and Ruoslahti, E. (1992) Natural inhibitor of transforming growth factor- β protects against scarring in experimental kidney disease. Nature 360, 361-364.
-
(1992)
Nature
, vol.360
, pp. 361-364
-
-
Border, W.A.1
Noble, N.A.2
Yamamoto, T.3
Harper, J.R.4
Yamaguchi, Y.5
Pierschbacher, M.D.6
Ruoslahti, E.7
-
18
-
-
0033619255
-
Silencing of TGF- β signalling by the pseudoreceptor BAMBI
-
Onichtchouk, D., Chen, Y. G., Dosch, R., Gawantka, V., Delius, H., Massague, J., and Niehrs, C. (1999) Silencing of TGF- β signalling by the pseudoreceptor BAMBI. Nature 401, 480-485.
-
(1999)
Nature
, vol.401
, pp. 480-485
-
-
Onichtchouk, D.1
Chen, Y.G.2
Dosch, R.3
Gawantka, V.4
Delius, H.5
Massagué, J.6
Niehrs, C.7
-
19
-
-
33847379496
-
The evolutionally conserved activity of Dapper2 in antagonizing TGF-, β signaling
-
Su, Y., Zhang, L., Gao, X., Meng, F., Wen, J., Zhou, H., Meng, A., and Chen, Y. G. (2007) The evolutionally conserved activity of Dapper2 in antagonizing TGF- β signaling. FASEB J. 21, 682-690.
-
(2007)
FASEB J
, vol.21
, pp. 682-690
-
-
Su, Y.1
Zhang, L.2
Gao, X.3
Meng, F.4
Wen, J.5
Zhou, H.6
Meng, A.7
Chen, Y.G.8
-
20
-
-
0033524943
-
Crystal structure of the cytoplasmic domain of the type I TGF β receptor in complex with FKBP12
-
Huse, M., Chen, Y. G., Massagué, J., and Kuriyan, J. (1999) Crystal structure of the cytoplasmic domain of the type I TGF β receptor in complex with FKBP12. Cell 96, 425-436.
-
(1999)
Cell
, vol.96
, pp. 425-436
-
-
Huse, M.1
Chen, Y.G.2
Massagué, J.3
Kuriyan, J.4
-
21
-
-
73649085521
-
TMEPAI, a transmembrane TGF- β -inducible protein, sequesters Smad proteins from active participation in TGF- β signaling
-
Watanabe, Y., Itoh, S., Goto, T., Ohnishi, E., Inamitsu, M., Itoh, F., Satoh, K., Wiercinska, E., Yang, W., Shi, L., Tanaka, A., Nakano, N., Mommaas, A. M., Shibuya, H., Ten Dijke, P., and Kato, M. (2010) TMEPAI, a transmembrane TGF- β -inducible protein, sequesters Smad proteins from active participation in TGF- β signaling. Mol. Cell 37, 123-134.
-
(2010)
Mol. Cell
, vol.37
, pp. 123-134
-
-
Watanabe, Y.1
Itoh, S.2
Goto, T.3
Ohnishi, E.4
Inamitsu, M.5
Itoh, F.6
Satoh, K.7
Wiercinska, E.8
Yang, W.9
Shi, L.10
Tanaka, A.11
Nakano, N.12
Mommaas, A.M.13
Shibuya, H.14
Ten Dijke, P.15
Kato, M.16
-
22
-
-
0033549789
-
A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
-
Zhu, H., Kavsak, P., Abdollah, S., Wrana, J. L., and Thomsen, G. H. (1999) A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400, 687-693.
-
(1999)
Nature
, vol.400
, pp. 687-693
-
-
Zhu, H.1
Kavsak, P.2
Abdollah, S.3
Wrana, J.L.4
Thomsen, G.H.5
-
23
-
-
0035918274
-
Smurf1 interacts with transforming growth factor- β type I receptor through Smad7 and induces receptor degradation
-
Ebisawa, T., Fukuchi, M., Murakami, G., Chiba, T., Tanaka, K., Imamura, T., and Miyazono, K. (2001) Smurf1 interacts with transforming growth factor- β type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem. 276, 12477-12480.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
Miyazono, K.7
-
24
-
-
0030611757
-
Identification of Smad7, a TGF β -inducible antagonist of TGF- β signalling
-
Nakao, A., Afrakhte, M., Morén, A., Nakayama, T., Christian, J. L., Heuchel, R., Itoh, S., Kawabata, M., Heldin, N. E., Heldin, C. H., and ten Dijke, P. (1997) Identification of Smad7, a TGF β -inducible antagonist of TGF- β signalling. Nature 389, 631-635.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Morén, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.E.9
Heldin, C.H.10
Ten Dijke, P.11
-
25
-
-
33646132747
-
Axin is a scaffold protein in TGF- β signaling that promotes degradation of Smad7 by Arkadia
-
Liu, W., Rui, H., Wang, J., Lin, S., He, Y., Chen, M., Li, Q., Ye, Z., Zhang, S., Chan, S. C., Chen, Y. G., Han, J., and Lin, S. C. (2006) Axin is a scaffold protein in TGF- β signaling that promotes degradation of Smad7 by Arkadia. EMBO J. 25, 1646-1658.
-
(2006)
EMBO J
, vol.25
, pp. 1646-1658
-
-
Liu, W.1
Rui, H.2
Wang, J.3
Lin, S.4
He, Y.5
Chen, M.6
Li, Q.7
Ye, Z.8
Zhang, S.9
Chan, S.C.10
Chen, Y.G.11
Han, J.12
Lin, S.C.13
-
26
-
-
13144258732
-
Twenty proteins containing a C-terminal SOCS box form five structural classes
-
Hilton, D. J., Richardson, R. T., Alexander, W. S., Viney, E. M., Willson, T. A., Sprigg, N. S., Starr, R., Nicholson, S. E., Metcalf, D., and Nicola, N. A. (1998) Twenty proteins containing a C-terminal SOCS box form five structural classes. Proc. Natl. Acad. Sci. U.S.A. 95, 114-119.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 114-119
-
-
Hilton, D.J.1
Richardson, R.T.2
Alexander, W.S.3
Viney, E.M.4
Willson, T.A.5
Sprigg, N.S.6
Starr, R.7
Nicholson, S.E.8
Metcalf, D.9
Nicola, N.A.10
-
27
-
-
18144383511
-
The SPRY domaincontaining SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway
-
Wang, D., Li, Z., Messing, E. M., and Wu, G. (2005) The SPRY domaincontaining SOCS box protein 1 (SSB-1) interacts with MET and enhances the hepatocyte growth factor-induced Erk-Elk-1-serum response element pathway. J. Biol. Chem. 280, 16393-16401.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16393-16401
-
-
Wang, D.1
Li, Z.2
Messing, E.M.3
Wu, G.4
-
28
-
-
30044451756
-
The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues
-
Masters, S. L., Yao, S., Willson, T. A., Zhang, J. G., Palmer, K. R., Smith, B. J., Babon, J. J., Nicola, N. A., Norton, R. S., and Nicholson, S. E. (2006) The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues. Nat. Struct. Mol. Biol. 13, 77-84.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 77-84
-
-
Masters, S.L.1
Yao, S.2
Willson, T.A.3
Zhang, J.G.4
Palmer, K.R.5
Smith, B.J.6
Babon, J.J.7
Nicola, N.A.8
Norton, R.S.9
Nicholson, S.E.10
-
29
-
-
0030974256
-
SPRY domains in ryanodine receptors (Ca2+-release channels)
-
Ponting, C., Schultz, J., and Bork, P. (1997) SPRY domains in ryanodine receptors (Ca2+-release channels). Trends Biochem. Sci. 22, 193-194.
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 193-194
-
-
Ponting, C.1
Schultz, J.2
Bork, P.3
-
30
-
-
28244438788
-
Relationship between SPRY and B30.2 protein domains: Evolution of a component of immune defence?
-
Rhodes, D. A., de Bono, B., and Trowsdale, J. (2005) Relationship between SPRY and B30.2 protein domains: evolution of a component of immune defence? Immunology 116, 411-417.
-
(2005)
Immunology
, vol.116
, pp. 411-417
-
-
Rhodes, D.A.1
De Bono, B.2
Trowsdale, J.3
-
31
-
-
61849184395
-
Divergence of the vertebrate sp1A/ryanodine receptor domain and SOCS box-containing (Spsb) gene family and its expression and regulation within the mouse brain
-
Kleiber, M. L., and Singh, S. M. (2009) Divergence of the vertebrate sp1A/ryanodine receptor domain and SOCS box-containing (Spsb) gene family and its expression and regulation within the mouse brain. Genomics 93, 358-366.
-
(2009)
Genomics
, vol.93
, pp. 358-366
-
-
Kleiber, M.L.1
Singh, S.M.2
-
32
-
-
0037183982
-
Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM
-
Wang, D., Li, Z., Messing, E. M., and Wu, G. (2002) Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM. J. Biol. Chem. 277, 36216-36222.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36216-36222
-
-
Wang, D.1
Li, Z.2
Messing, E.M.3
Wu, G.4
-
33
-
-
0347627145
-
A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling
-
Wang, D., Li, Z., Schoen, S. R., Messing, E. M., and Wu, G. (2004) A novel MET-interacting protein shares high sequence similarity with RanBPM, but fails to stimulate MET-induced Ras/Erk signaling. Biochem. Biophys. Res. Commun. 313, 320-326.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.313
, pp. 320-326
-
-
Wang, D.1
Li, Z.2
Schoen, S.R.3
Messing, E.M.4
Wu, G.5
-
34
-
-
34247341367
-
TRIM25 RINGfinger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
-
Gack, M. U., Shin, Y. C., Joo, C. H., Urano, T., Liang, C., Sun, L., Takeuchi, O., Akira, S., Chen, Z., Inoue, S., and Jung, J. U. (2007) TRIM25 RINGfinger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 446, 916-920.
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
Shin, Y.C.2
Joo, C.H.3
Urano, T.4
Liang, C.5
Sun, L.6
Takeuchi, O.7
Akira, S.8
Chen, Z.9
Inoue, S.10
Jung, J.U.11
-
35
-
-
0036558025
-
The SOCS box: A tale of destruction and degradation
-
Kile, B. T., Schulman, B. A., Alexander, W. S., Nicola, N. A., Martin, H. M., and Hilton, D. J. (2002) The SOCS box: A tale of destruction and degradation. Trends Biochem. Sci. 27, 235-241.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 235-241
-
-
Kile, B.T.1
Schulman, B.A.2
Alexander, W.S.3
Nicola, N.A.4
Martin, H.M.5
Hilton, D.J.6
-
36
-
-
20744436628
-
Genetic deletion of murine SPRY domain-containing SOCS box protein 2 (SSB-2) results in very mild thrombocytopenia
-
Masters, S. L., Palmer, K. R., Stevenson, W. S., Metcalf, D., Viney, E. M., Sprigg, N. S., Alexander, W. S., Nicola, N. A., and Nicholson, S. E. (2005) Genetic deletion of murine SPRY domain-containing SOCS box protein 2 (SSB-2) results in very mild thrombocytopenia. Mol. Cell. Biol. 25, 5639-5647.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5639-5647
-
-
Masters, S.L.1
Palmer, K.R.2
Stevenson, W.S.3
Metcalf, D.4
Viney, E.M.5
Sprigg, N.S.6
Alexander, W.S.7
Nicola, N.A.8
Nicholson, S.E.9
-
37
-
-
77954709822
-
The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation
-
Kuang, Z., Lewis, R. S., Curtis, J. M., Zhan, Y., Saunders, B. M., Babon, J. J., Kolesnik, T. B., Low, A., Masters, S. L., Willson, T. A., Kedzierski, L., Yao, S., Handman, E., Norton, R. S., and Nicholson, S. E. (2010) The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation. J. Cell Biol. 190, 129-141.
-
(2010)
J. Cell Biol.
, vol.190
, pp. 129-141
-
-
Kuang, Z.1
Lewis, R.S.2
Curtis, J.M.3
Zhan, Y.4
Saunders, B.M.5
Babon, J.J.6
Kolesnik, T.B.7
Low, A.8
Masters, S.L.9
Willson, T.A.10
Kedzierski, L.11
Yao, S.12
Handman, E.13
Norton, R.S.14
Nicholson, S.E.15
-
38
-
-
80053491919
-
TLR regulation of SPSB1 controls inducible nitric oxide synthase induction
-
Lewis, R. S., Kolesnik, T. B., Kuang, Z., D'Cruz, A. A., Blewitt, M. E., Masters, S. L., Low, A., Willson, T., Norton, R. S., and Nicholson, S. E. (2011) TLR regulation of SPSB1 controls inducible nitric oxide synthase induction. J. Immunol. 187, 3798-3805.
-
(2011)
J. Immunol.
, vol.187
, pp. 3798-3805
-
-
Lewis, R.S.1
Kolesnik, T.B.2
Kuang, Z.3
D'Cruz, A.A.4
Blewitt, M.E.5
Masters, S.L.6
Low, A.7
Willson, T.8
Norton, R.S.9
Nicholson, S.E.10
-
39
-
-
79953192137
-
Regulation of inducible nitric-oxide synthase by the SPRY domain- And SOCS boxcontaining proteins
-
Nishiya, T., Matsumoto, K., Maekawa, S., Kajita, E., Horinouchi, T., Fujimuro, M., Ogasawara, K., Uehara, T., and Miwa, S. (2011) Regulation of inducible nitric-oxide synthase by the SPRY domain- And SOCS boxcontaining proteins. J. Biol. Chem. 286, 9009-9019.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 9009-9019
-
-
Nishiya, T.1
Matsumoto, K.2
Maekawa, S.3
Kajita, E.4
Horinouchi, T.5
Fujimuro, M.6
Ogasawara, K.7
Uehara, T.8
Miwa, S.9
-
40
-
-
16344378397
-
TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition
-
Valcourt, U., Kowanetz, M., Niimi, H., Heldin, C. H., and Moustakas, A. (2005) TGF-beta and the Smad signaling pathway support transcriptomic reprogramming during epithelial-mesenchymal cell transition. Mol. Biol. Cell 16, 1987-2002.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 1987-2002
-
-
Valcourt, U.1
Kowanetz, M.2
Niimi, H.3
Heldin, C.H.4
Moustakas, A.5
-
41
-
-
0033597206
-
Apivotal role for the transmembrane domain in transforming growth factor-beta receptor activation
-
Zhu, H. J., and Sizeland, A. M. (1999)Apivotal role for the transmembrane domain in transforming growth factor-beta receptor activation. J. Biol. Chem. 274, 11773-11781.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 11773-11781
-
-
Zhu, H.J.1
Sizeland, A.M.2
-
42
-
-
59649089239
-
SPRY domain-containing SOCS box protein 2: Crystal structure and residues critical for protein binding
-
Kuang, Z., Yao, S., Xu, Y., Lewis, R. S., Low, A., Masters, S. L., Willson, T. A., Kolesnik, T. B., Nicholson, S. E., Garrett, T. J., and Norton, R. S. (2009) SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding. J. Mol. Biol. 386, 662-674.
-
(2009)
J. Mol. Biol.
, vol.386
, pp. 662-674
-
-
Kuang, Z.1
Yao, S.2
Xu, Y.3
Lewis, R.S.4
Low, A.5
Masters, S.L.6
Willson, T.A.7
Kolesnik, T.B.8
Nicholson, S.E.9
Garrett, T.J.10
Norton, R.S.11
-
43
-
-
14444288522
-
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
-
Huang, H. S., Nagane, M., Klingbeil, C. K., Lin, H., Nishikawa, R., Ji, X. D., Huang, C. M., Gill, G. N., Wiley, H. S., and Cavenee, W. K. (1997) The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J. Biol. Chem. 272, 2927-2935.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2927-2935
-
-
Huang, H.S.1
Nagane, M.2
Klingbeil, C.K.3
Lin, H.4
Nishikawa, R.5
Ji, X.D.6
Huang, C.M.7
Gill, G.N.8
Wiley, H.S.9
Cavenee, W.K.10
-
44
-
-
0035878671
-
Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR
-
Luwor, R. B., Johns, T. G., Murone, C., Huang, H. J., Cavenee, W. K., Ritter, G., Old, L. J., Burgess, A. W., and Scott, A. M. (2001) Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR. Cancer Res. 61, 5355-5361.
-
(2001)
Cancer Res.
, vol.61
, pp. 5355-5361
-
-
Luwor, R.B.1
Johns, T.G.2
Murone, C.3
Huang, H.J.4
Cavenee, W.K.5
Ritter, G.6
Old, L.J.7
Burgess, A.W.8
Scott, A.M.9
-
45
-
-
4444263448
-
The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR
-
Luwor, R. B., Zhu, H. J., Walker, F., Vitali, A. A., Perera, R. M., Burgess, A. W., Scott, A. M., and Johns, T. G. (2004) The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. Oncogene 23, 6095-6104.
-
(2004)
Oncogene
, vol.23
, pp. 6095-6104
-
-
Luwor, R.B.1
Zhu, H.J.2
Walker, F.3
Vitali, A.A.4
Perera, R.M.5
Burgess, A.W.6
Scott, A.M.7
Johns, T.G.8
-
46
-
-
33644849337
-
Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels
-
Wild, R., Fager, K., Flefleh, C., Kan, D., Inigo, I., Castaneda, S., Luo, F. R., Camuso, A., McGlinchey, K., and Rose, W. C. (2006) Cetuximab preclinical antitumor activity (monotherapy and combination based) is not predicted by relative total or activated epidermal growth factor receptor tumor expression levels. Mol. Cancer Ther. 5, 104-113.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 104-113
-
-
Wild, R.1
Fager, K.2
Flefleh, C.3
Kan, D.4
Inigo, I.5
Castaneda, S.6
Luo, F.R.7
Camuso, A.8
McGlinchey, K.9
Rose, W.C.10
-
47
-
-
0037744670
-
Epidermal growth factor receptor: Association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand
-
Zhu, H. J., Iaria, J., Orchard, S., Walker, F., and Burgess, A. W. (2003) Epidermal growth factor receptor: Association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand. Growth Factors 21, 15-30.
-
(2003)
Growth Factors
, vol.21
, pp. 15-30
-
-
Zhu, H.J.1
Iaria, J.2
Orchard, S.3
Walker, F.4
Burgess, A.W.5
-
48
-
-
0033527741
-
Smad7 differentially regulates transforming growth factor β-mediated signaling pathways
-
Zhu, H. J., Iaria, J., and Sizeland, A. M. (1999) Smad7 differentially regulates transforming growth factor β-mediated signaling pathways. J. Biol. Chem. 274, 32258-32264.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32258-32264
-
-
Zhu, H.J.1
Iaria, J.2
Sizeland, A.M.3
-
49
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S., and Gauthier, J. M. (1998) Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17, 3091-3100.
-
(1998)
EMBO J.
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
50
-
-
80052872201
-
New reagents for improved in vitro and in vivo examination of TGF-β signalling
-
Luwor, R. B., Wang, B., Nheu, T. V., Iaria, J., Tsantikos, E., Hibbs, M. L., Sieber, O. M., and Zhu, H. J. (2011) New reagents for improved in vitro and in vivo examination of TGF-β signalling. Growth Factors 29, 211-218.
-
(2011)
Growth Factors
, vol.29
, pp. 211-218
-
-
Luwor, R.B.1
Wang, B.2
Nheu, T.V.3
Iaria, J.4
Tsantikos, E.5
Hibbs, M.L.6
Sieber, O.M.7
Zhu, H.J.8
-
51
-
-
0033595704
-
Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein
-
Stroschein, S. L., Wang, W., Zhou, S., Zhou, Q., and Luo, K. (1999) Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein. Science 286, 771-774.
-
(1999)
Science
, vol.286
, pp. 771-774
-
-
Stroschein, S.L.1
Wang, W.2
Zhou, S.3
Zhou, Q.4
Luo, K.5
-
52
-
-
0035818573
-
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
-
Zhang, J. G., Metcalf, D., Rakar, S., Asimakis, M., Greenhalgh, C. J., Willson, T. A., Starr, R., Nicholson, S. E., Carter, W., Alexander, W. S., Hilton, D. J., and Nicola, N. A. (2001) The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo. Proc. Natl. Acad. Sci. U. S. A. 98, 13261-13265.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 13261-13265
-
-
Zhang, J.G.1
Metcalf, D.2
Rakar, S.3
Asimakis, M.4
Greenhalgh, C.J.5
Willson, T.A.6
Starr, R.7
Nicholson, S.E.8
Carter, W.9
Alexander, W.S.10
Hilton, D.J.11
Nicola, N.A.12
-
53
-
-
0036986179
-
Suppressors of cytokine signalling: SOCS
-
Larsen, L., and Röpke, C. (2002) Suppressors of cytokine signalling: SOCS. APMIS 110, 833-844.
-
(2002)
APMIS
, vol.110
, pp. 833-844
-
-
Larsen, L.1
Röpke, C.2
-
54
-
-
20144380439
-
SOCS2 negatively regulates growth hormone action in vitro and in vivo
-
Greenhalgh, C. J., Rico-Bautista, E., Lorentzon, M., Thaus, A. L., Morgan, P. O., Willson, T. A., Zervoudakis, P., Metcalf, D., Street, I., Nicola, N. A., Nash, A. D., Fabri, L. J., Norstedt, G., Ohlsson, C., Flores-Morales, A., Alexander, W. S., and Hilton, D. J. (2005) SOCS2 negatively regulates growth hormone action in vitro and in vivo. J. Clin. Invest. 115, 397-406.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 397-406
-
-
Greenhalgh, C.J.1
Rico-Bautista, E.2
Lorentzon, M.3
Thaus, A.L.4
Morgan, P.O.5
Willson, T.A.6
Zervoudakis, P.7
Metcalf, D.8
Street, I.9
Nicola, N.A.10
Nash, A.D.11
Fabri, L.J.12
Norstedt, G.13
Ohlsson, C.14
Flores-Morales, A.15
Alexander, W.S.16
Hilton, D.J.17
-
55
-
-
20244384804
-
Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling
-
Nicholson, S. E., Metcalf, D., Sprigg, N. S., Columbus, R., Walker, F., Silva, A., Cary, D., Willson, T. A., Zhang, J. G., Hilton, D. J., Alexander, W. S., and Nicola, N. A. (2005) Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling. Proc. Natl. Acad. Sci. U.S.A. 102, 2328-2333.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 2328-2333
-
-
Nicholson, S.E.1
Metcalf, D.2
Sprigg, N.S.3
Columbus, R.4
Walker, F.5
Silva, A.6
Cary, D.7
Willson, T.A.8
Zhang, J.G.9
Hilton, D.J.10
Alexander, W.S.11
Nicola, N.A.12
-
56
-
-
34548834429
-
The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo
-
Boyle, K., Egan, P., Rakar, S., Willson, T. A., Wicks, I. P., Metcalf, D., Hilton, D. J., Nicola, N. A., Alexander, W. S., Roberts, A. W., and Robb, L. (2007) The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo. Blood 110, 1466-1474.
-
(2007)
Blood
, vol.110
, pp. 1466-1474
-
-
Boyle, K.1
Egan, P.2
Rakar, S.3
Willson, T.A.4
Wicks, I.P.5
Metcalf, D.6
Hilton, D.J.7
Nicola, N.A.8
Alexander, W.S.9
Roberts, A.W.10
Robb, L.11
-
57
-
-
33845663050
-
Structural basis for protein recognition by B30.2/SPRY domains
-
Woo, J. S., Suh, H. Y., Park, S. Y., and Oh, B. H. (2006) Structural basis for protein recognition by B30.2/SPRY domains. Mol. Cell 24, 967-976.
-
(2006)
Mol. Cell
, vol.24
, pp. 967-976
-
-
Woo, J.S.1
Suh, H.Y.2
Park, S.Y.3
Oh, B.H.4
-
58
-
-
77955269719
-
Structural basis for Par-4 recognition by the SPRY domainand SOCS box-containing proteins SPSB1, SPSB2, and SPSB4
-
Filippakopoulos, P., Low, A., Sharpe, T. D., Uppenberg, J., Yao, S., Kuang, Z., Savitsky, P., Lewis, R. S., Nicholson, S. E., Norton, R. S., and Bullock, A. N. (2010) Structural basis for Par-4 recognition by the SPRY domainand SOCS box-containing proteins SPSB1, SPSB2, and SPSB4. J. Mol. Biol. 401, 389-402.
-
(2010)
J. Mol. Biol.
, vol.401
, pp. 389-402
-
-
Filippakopoulos, P.1
Low, A.2
Sharpe, T.D.3
Uppenberg, J.4
Yao, S.5
Kuang, Z.6
Savitsky, P.7
Lewis, R.S.8
Nicholson, S.E.9
Norton, R.S.10
Bullock, A.N.11
-
59
-
-
0035918239
-
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2
-
Kamizono, S., Hanada, T., Yasukawa, H., Minoguchi, S., Kato, R., Minoguchi, M., Hattori, K., Hatakeyama, S., Yada, M., Morita, S., Kitamura, T., Kato, H., Nakayama, K., and Yoshimura, A. (2001) The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. J. Biol. Chem. 276, 12530-12538.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12530-12538
-
-
Kamizono, S.1
Hanada, T.2
Yasukawa, H.3
Minoguchi, S.4
Kato, R.5
Minoguchi, M.6
Hattori, K.7
Hatakeyama, S.8
Yada, M.9
Morita, S.10
Kitamura, T.11
Kato, H.12
Nakayama, K.13
Yoshimura, A.14
-
60
-
-
33845524970
-
Transforming growth factorβ in cancer and metastasis
-
Jakowlew, S. B. (2006) Transforming growth factorβ in cancer and metastasis. Cancer Metastasis Rev. 25, 435-457.
-
(2006)
Cancer Metastasis Rev.
, vol.25
, pp. 435-457
-
-
Jakowlew, S.B.1
-
61
-
-
33646562542
-
The logic of TGF β signaling
-
Massagué, J., and Gomis, R. R. (2006) The logic of TGF β signaling. FEBS Lett. 580, 2811-2820.
-
(2006)
FEBS Lett.
, vol.580
, pp. 2811-2820
-
-
Massagué, J.1
Gomis, R.R.2
-
62
-
-
30944436222
-
Smad3 phosphorylation by cyclin-dependent kinases
-
Liu, F. (2006) Smad3 phosphorylation by cyclin-dependent kinases. Cytokine Growth Factor Rev. 17, 9-17.
-
(2006)
Cytokine Growth Factor Rev.
, vol.17
, pp. 9-17
-
-
Liu, F.1
-
63
-
-
0033106484
-
A mechanism of repression of TGF β/Smad signaling by oncogenic Ras
-
Kretzschmar, M., Doody, J., Timokhina, I., and Massagué, J. (1999) A mechanism of repression of TGF β/Smad signaling by oncogenic Ras. Genes Dev. 13, 804-816.
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massagué, J.4
-
64
-
-
27644494876
-
Smad transcription factors
-
Massagué, J., Seoane, J., and Wotton, D. (2005) Smad transcription factors. Genes Dev. 19, 2783-2810.
-
(2005)
Genes Dev.
, vol.19
, pp. 2783-2810
-
-
Massagué, J.1
Seoane, J.2
Wotton, D.3
-
65
-
-
71049139747
-
Human BAMBI cooperates with Smad7 to inhibit transforming growth factorβ signaling
-
Yan, X., Lin, Z., Chen, F., Zhao, X., Chen, H., Ning, Y., and Chen, Y. G. (2009) Human BAMBI cooperates with Smad7 to inhibit transforming growth factorβ signaling. J. Biol. Chem. 284, 30097-30104.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 30097-30104
-
-
Yan, X.1
Lin, Z.2
Chen, F.3
Zhao, X.4
Chen, H.5
Ning, Y.6
Chen, Y.G.7
-
66
-
-
3042801616
-
Transcriptional regulation of the TGFβ pseudoreceptor BAMBI by TGFβ signaling
-
Sekiya, T., Oda, T., Matsuura, K., and Akiyama, T. (2004) Transcriptional regulation of the TGFβ pseudoreceptor BAMBI by TGFβ signaling. Biochem. Biophys. Res. Commun. 320, 680-684.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 680-684
-
-
Sekiya, T.1
Oda, T.2
Matsuura, K.3
Akiyama, T.4
-
67
-
-
28044451534
-
The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGFβ signaling by inactivating the TGFβ type II receptor
-
Jin, W., Kim, B. C., Tognon, C., Lee, H. J., Patel, S., Lannon, C. L., Maris, J. M., Triche, T. J., Sorensen, P. H., and Kim, S. J. (2005) The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGFβ signaling by inactivating the TGFβ type II receptor. Proc. Natl. Acad. Sci. U.S.A. 102, 16239-16244.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 16239-16244
-
-
Jin, W.1
Kim, B.C.2
Tognon, C.3
Lee, H.J.4
Patel, S.5
Lannon, C.L.6
Maris, J.M.7
Triche, T.J.8
Sorensen, P.H.9
Kim, S.J.10
-
68
-
-
36849008767
-
TrkC binds to the type II TGFβ receptor to suppress TGFβ signaling
-
Jin, W., Yun, C., Kwak, M. K., Kim, T. A., and Kim, S. J. (2007) TrkC binds to the type II TGFβ receptor to suppress TGFβ signaling. Oncogene 26, 7684-7691.
-
(2007)
Oncogene
, vol.26
, pp. 7684-7691
-
-
Jin, W.1
Yun, C.2
Kwak, M.K.3
Kim, T.A.4
Kim, S.J.5
-
69
-
-
0035794218
-
Caveolin-1 regulates transforming growth factor (TGF)β/SMAD signaling through an interaction with the TGFβ type I receptor
-
Razani, B., Zhang, X. L., Bitzer, M., von Gersdorff, G., Böttinger, E. P., and Lisanti, M. P. (2001) Caveolin-1 regulates transforming growth factor (TGF)β/SMAD signaling through an interaction with the TGFβ type I receptor. J. Biol. Chem. 276, 6727-6738.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6727-6738
-
-
Razani, B.1
Zhang, X.L.2
Bitzer, M.3
Von Gersdorff, G.4
Böttinger, E.P.5
Lisanti, M.P.6
-
70
-
-
2942614808
-
Hyaluronan regulates transforming growth factorβ1 receptor compartmentalization
-
Ito, T., Williams, J. D., Fraser, D. J., and Phillips, A. O. (2004) Hyaluronan regulates transforming growth factorβ1 receptor compartmentalization. J. Biol. Chem. 279, 25326-25332.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25326-25332
-
-
Ito, T.1
Williams, J.D.2
Fraser, D.J.3
Phillips, A.O.4
-
71
-
-
0037131283
-
Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane
-
Suzuki, C., Murakami, G., Fukuchi, M., Shimanuki, T., Shikauchi, Y., Imamura, T., and Miyazono, K. (2002) Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane. J. Biol. Chem. 277, 39919-39925.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39919-39925
-
-
Suzuki, C.1
Murakami, G.2
Fukuchi, M.3
Shimanuki, T.4
Shikauchi, Y.5
Imamura, T.6
Miyazono, K.7
-
72
-
-
14844364701
-
Regulation of the polarity protein Part by TGFβreceptors controls epithelial cell plasticity
-
Ozdamar, B., Bose, R., Barrios-Rodiles, M., Wang, H. R., Zhang, Y., and Wrana, J. L. (2005) Regulation of the polarity protein Par6 by TGFβreceptors controls epithelial cell plasticity. Science 307, 1603-1609.
-
(2005)
Science
, vol.307
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.R.4
Zhang, Y.5
Wrana, J.L.6
-
73
-
-
34447508438
-
The disintegrin and metalloproteinase ADAM12 contributes to TGFβ signaling through interaction with the type II receptor
-
Atfi, A., Dumont, E., Colland, F., Bonnier, D., L'Helgoualc'h, A., Prunier, C., Ferrand, N., Clément, B., Wewer, U. M., and Théret, N. (2007) The disintegrin and metalloproteinase ADAM12 contributes to TGFβ signaling through interaction with the type II receptor. J. Cell Biol. 178, 201-208.
-
(2007)
J. Cell Biol.
, vol.178
, pp. 201-208
-
-
Atfi, A.1
Dumont, E.2
Colland, F.3
Bonnier, D.4
L'Helgoualc'h, A.5
Prunier, C.6
Ferrand, N.7
Clément, B.8
Wewer, U.M.9
Théret, N.10
-
74
-
-
77949346488
-
Regulation of Drosophila vasa in vivo through paralogous cullin-RING E3 ligase specificity receptors
-
Kugler, J. M., Woo, J. S., Oh, B. H., and Lasko, P. (2010) Regulation of Drosophila vasa in vivo through paralogous cullin-RING E3 ligase specificity receptors. Mol. Cell. Biol. 30, 1769-1782.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 1769-1782
-
-
Kugler, J.M.1
Woo, J.S.2
Oh, B.H.3
Lasko, P.4
-
75
-
-
0029033910
-
Independent changes in type I and type II receptors for transforming growth factor - induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype
-
Centrella, M., Casinghino, S., Kim, J., Pham, T., Rosen, V., Wozney, J., and McCarthy, T. L. (1995) Independent changes in type I and type II receptors for transforming growth factor - induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype. Mol. Cell. Biol. 15, 3273-3281.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3273-3281
-
-
Centrella, M.1
Casinghino, S.2
Kim, J.3
Pham, T.4
Rosen, V.5
Wozney, J.6
McCarthy, T.L.7
-
76
-
-
0029763520
-
Rapid flux in transforming growth factorβ receptors on bone cells
-
Centrella, M., Ji, C., Casinghino, S., and McCarthy, T. L. (1996) Rapid flux in transforming growth factorβ receptors on bone cells. J. Biol. Chem. 271, 18616-18622.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18616-18622
-
-
Centrella, M.1
Ji, C.2
Casinghino, S.3
McCarthy, T.L.4
-
77
-
-
0030970688
-
Expression and functions of EGF, FGF and TGF-growth-factor family members and their receptors in invasive human transitional-cell-carcinoma cells
-
De Boer, W. I., Houtsmuller, A. B., Izadifar, V., Muscatelli-Groux, B., Van der Kwast, T. H., and Chopin, D. K. (1997) Expression and functions of EGF, FGF and TGF-growth-factor family members and their receptors in invasive human transitional-cell-carcinoma cells. Int. J. Cancer 71, 284-291.
-
(1997)
Int. J. Cancer
, vol.71
, pp. 284-291
-
-
De Boer, W.I.1
Houtsmuller, A.B.2
Izadifar, V.3
Muscatelli-Groux, B.4
Van Der Kwast, T.H.5
Chopin, D.K.6
-
78
-
-
0030965611
-
Processing of the transforming growth factor - type I and II receptors: Biosynthesis and ligand-induced regulation
-
Koli, K. M., and Arteaga, C. L. (1997) Processing of the transforming growth factor - type I and II receptors: biosynthesis and ligand-induced regulation. J. Biol. Chem. 272, 6423-6427.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6423-6427
-
-
Koli, K.M.1
Arteaga, C.L.2
-
79
-
-
0032483418
-
Differential requirement for type I and type II transforming growth factor βreceptor kinase activity in ligand-mediated receptor endocytosis
-
Anders, R. A., Doré, J. J. Jr., Arline, S. L., Garamszegi, N., and Leof, E. B. (1998) Differential requirement for type I and type II transforming growth factor βreceptor kinase activity in ligand-mediated receptor endocytosis. J. Biol. Chem. 273, 23118-23125.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23118-23125
-
-
Anders, R.A.1
Doré, J.J.2
Arline, S.L.3
Garamszegi, N.4
Leof, E.B.5
-
80
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation
-
Kavsak, P., Rasmussen, R. K., Causing, C. G., Bonni, S., Zhu, H., Thomsen, G. H., and Wrana, J. L. (2000) Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF β receptor for degradation. Mol. Cell 6, 1365-1375.
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
81
-
-
3142546336
-
Cyclin-dependent kinases regulate the antiproliferative function of Smads
-
Matsuura, I., Denissova, N. G., Wang, G., He, D., Long, J., and Liu, F. (2004) Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 430, 226-231.
-
(2004)
Nature
, vol.430
, pp. 226-231
-
-
Matsuura, I.1
Denissova, N.G.2
Wang, G.3
He, D.4
Long, J.5
Liu, F.6
-
82
-
-
0035501062
-
TGFβ signaling in cancer: A doubleedged sword
-
Akhurst, R. J., and Derynck, R. (2001) TGFβ signaling in cancer: A doubleedged sword. Trends Cell Biol. 11, S44-S51.
-
(2001)
Trends Cell Biol
, vol.11
, pp. S44-S51
-
-
Akhurst, R.J.1
Derynck, R.2
-
83
-
-
35048875855
-
TGFβ signaling: A tale of two responses
-
Rahimi, R. A., and Leof, E. B. (2007) TGFβ signaling: A tale of two responses. J. Cell. Biochem. 102, 593-608.
-
(2007)
J. Cell. Biochem.
, vol.102
, pp. 593-608
-
-
Rahimi, R.A.1
Leof, E.B.2
-
84
-
-
0242499448
-
Cytostatic and apoptotic actions of TGFβ in homeostasis and cancer
-
Siegel, P. M., and Massagué, J. (2003) Cytostatic and apoptotic actions of TGFβ in homeostasis and cancer. Nat. Rev. Cancer 3, 807-821.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massagué, J.2
|