MERIT40 deficiency expands hematopoietic stem cell pools by regulating thrombopoietin receptor signaling

Blood

Volumn 125, Issue 11, 2015, Pages 1730-1738

  Rozenova, Krasimira ^a,b   Jiang, Jing ^a,b   Donaghy, Ryan ^a   Aressy, Bernadette ^b   Greenberg, Roger A ^b   Tong, Wei ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; MEDIATOR OF RAP80 INTERACTIONS AND TARGETING 40 KDA; PROTEIN; THROMBOPOIETIN RECEPTOR; UNCLASSIFIED DRUG; DEUBIQUITINASE; MERIT40 PROTEIN, MOUSE; MPL PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; THROMBOPOIETIN;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL DIVISION; CELL EXPANSION; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL SELF-RENEWAL; THROMBOCYTE COUNT; UBIQUITINATION; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CFU COUNTING; CYTOLOGY; DEFICIENCY; DRUG EFFECTS; FEMALE; GENETICS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; KNOCKOUT MOUSE; MALE; METABOLISM; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL CYCLE; CELL PROLIFERATION; COLONY-FORMING UNITS ASSAY; FEMALE; FLUOROURACIL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, THROMBOPOIETIN; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; THROMBOPOIETIN; UBIQUITIN-SPECIFIC PROTEASES;

EID: 84937454590     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-07-588145     Document Type: Article

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