Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis

Journal of Experimental Medicine

Volumn 200, Issue 5, 2004, Pages 569-580

  Tong, Wei ^a   Lodish, Harvey F ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cell proliferation; Cytokine receptors; Endomitosis; Hematopoiesis; Megakaryocytes

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; STAT3 PROTEIN; STAT5 PROTEIN; THROMBOPOIETIN;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL COUNT; CELL CULTURE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HEMATOPOIETIC CELL; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MITOSIS; MOUSE; NONHUMAN; PLOIDY; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; SPLEEN CELL; SRC HOMOLOGY DOMAIN; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOTTING, WESTERN; BONE MARROW CELLS; CELL DIVISION; CYTOKINES; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENETIC VECTORS; GENOTYPE; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MEGAKARYOCYTES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MILK PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MITOSIS; MODELS, STATISTICAL; NEOPLASM PROTEINS; PLATELET MEMBRANE GLYCOPROTEIN IIB; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CYTOKINE; RECEPTORS, THROMBOPOIETIN; RETROVIRIDAE; SIGNAL TRANSDUCTION; SPLEEN; SRC HOMOLOGY DOMAINS; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR; THROMBOPOIETIN; TIME FACTORS; TRANS-ACTIVATORS;

EID: 4544277651     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20040762     Document Type: Article

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