GABA B Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

Neuropsychopharmacology

Volumn 40, Issue 9, 2015, Pages 2228-2239

  Silverman, J L ^a   Pride, M C ^a   Hayes, J E ^a   Puhger, K R ^a   Butler Struben, H M ^a   Baker, S ^a   Crawley, J N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACLOFEN; 4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; COMPULSION; CONTROLLED STUDY; DRUG EFFECT; ENANTIOMER; GROOMING; MOUSE; MOUSE MODEL; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL; SOCIAL DISABILITY; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; COMPLICATION; CUMULATIVE TRAUMA DISORDERS; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; EXPLORATORY BEHAVIOR; GENETICS; LOCOMOTION; MOUSE MUTANT; SOCIAL BEHAVIOR DISORDERS;

ANALYSIS OF VARIANCE; ANIMALS; AUTISTIC DISORDER; BACLOFEN; CUMULATIVE TRAUMA DISORDERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; GABA-B RECEPTOR AGONISTS; GROOMING; LOCOMOTION; MICE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; SOCIAL BEHAVIOR DISORDERS;

EID: 84937164423     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.66     Document Type: Article

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