Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndrome

Journal of Neuroscience

Volumn 30, Issue 29, 2010, Pages 9929-9938

  Olmos Serrano, Jose Luis ^a   Paluszkiewicz, Scott M ^a,b   Martin, Brandon S ^a,b   Kaufmann, Walter E ^c   Corbin, Joshua G ^a   Huntsman, Molly M ^a  

^a CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN; GABOXADOL;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FRAGILE X SYNDROME; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; INTRACELLULAR SIGNALING; KNOCKOUT MOUSE; MALE; MOUSE; NERVE CELL EXCITABILITY; NERVE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC INHIBITION;

AMYGDALA; ANIMALS; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; INTERNEURONS; ISOXAZOLES; MALE; MICE; MICE, KNOCKOUT; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; SYNAPTIC TRANSMISSION;

EID: 77954851827     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1714-10.2010     Document Type: Article

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