Assessing autism-like behavior in mice: Variations in social interactions among inbred strains

Behavioural Brain Research

Volumn 176, Issue 1, 2007, Pages 21-26

  Bolivar, Valerie J ^a,b   Walters, Samantha R ^a   Phoenix, Jennifer L ^a  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Autism; Huddling; Inbred strain; Mouse; Mouse model; Sniffing; Social behavior; Wrestling

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTISM; BEHAVIOR; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENETIC LINKAGE; HUNTINGTON CHOREA; INBRED STRAIN; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOCIAL BEHAVIOR; SOCIAL INTERACTION;

ANIMALS; AUTISTIC DISORDER; BEHAVIOR, ANIMAL; DISEASE MODELS, ANIMAL; FEMALE; GENETICS, BEHAVIORAL; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, INBRED STRAINS; SOCIAL BEHAVIOR; SPECIES SPECIFICITY;

EID: 33845336461     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2006.09.007     Document Type: Article

References (56)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). 4th ed. (1994), American Psychiatric Association, Washington, DC
2. Andres C. Molecular genetics and animal models in autistic disorders. Brain Res Bull 57 (2002) 109-119
3. Asperger H. Autistic psychopathology in childhood. Translated and annotated by U. Frith. In: Frith U. (Ed). Autism and Asperger syndrome (1944/1991), Cambridge University Press, Cambridge 37-92
4. Baron-Cohen S., Ring H.A., Bullmore E.T., Wheelwright S., Ashwin C., and Williams S.C.R. The amygdala theory of autism. Neurosci Biobehav Rev 24 (2000) 355-364
5. Blanchard D.C., and Blanchard R.J. Ethoexperimental approaches to the biology of emotion. Ann Rev Psychol 39 (1988) 43-68
6. Bolivar V.J., Caldarone B.J., Reilly A.A., and Flaherty L. Habituation of activity in an open field: a survey of inbred strains and F1 hybrids. Behav Genet 30 (2000) 285-293
7. Bolivar V.J., and Flaherty L. Assessing autism-like behaviors in inbred strains of mice. Society For Neuroscience Abstract 318 (2003) 13
8. Bolivar V.J., and Flaherty L. Genetic control of novel food preference in mice. Mamm Genome 15 (2004) 193-198
9. Bolivar V.J., Ganus J.S., and Messer A. The development of behavioral abnormalities in the motor neuron degeneration (mnd) mouse. Brain Res 937 (2002) 74-82
10. Bolivar V.J., Pooler O., and Flaherty L. Inbred strain variation in contextual and cued fear conditioning behavior. Mamm Genome 12 (2001) 651-656
11. Brambilla P., Hardan A., Ucelli di Nemi S., Perez J., Soares J.C., and Barale F. Brain anatomy and development in autism: review of structural MRI studies. Brain Res Bull 61 (2003) 557-569
12. Brodkin E.S., Hagemann A., Nemetski S.M., and Silver L.M. Social approach-avoidance behavior of inbred mouse strains towards DBA/2 mice. Brain Res 1002 (2004) 151-157
13. Bucan M., and Abel T. The mouse: genetics meets behaviour. Nat Rev Genet 3 (2002) 114-123
14. Carlsson M.I. Hypothesis: is infantile autism a hypoglutamatergic disorder? Relevance of glutamate-serotonin interactions for pharmacotherapy. J Neural Transm 105 (1998) 525-535
15. Cody H., Pelphrey K., and Piven J. Structural and functional magnetic resonance imaging of autism. Int J Dev Neurosci 20 (2002) 421-438
16. Cook E.H., and Leventhal B.L. The serotonin system in autism. Curr Opin Pediatr 8 (1996) 348-354
17. Cook M.N., Bolivar V.J., McFadyen M.P., and Flaherty L. Behavioral differences among 129 substrains: implications for knockout and transgenic mice. Behav Neurosci 116 (2002) 600-611
18. Cook M.N., Williams R.W., and Flaherty L. Anxiety-related behaviors in the elevated zero-maze are affected by genetic factors and retinal degeneration. Behav Neurosci 115 (2001) 468-476
19. Crawley J.N. What's wrong with my mouse? (2000), John Wiley & Sons Inc., New York p. 329
20. Crawley J.N. Designing mouse behavioral tasks relevant to autistic-like behaviors. Ment Retard Dev Disabil Res Rev 10 (2004) 248-258
21. Crawley J.N., Belknap J.K., Collins A., Crabbe J.C., Frankel W., Henderson N., et al. Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies. Psychopharmacology 132 (1997) 107-124
22. DCicco-Bloom E., Lord C., Zwaigenbaum L., Courchesne E., Dager S.R., Schmitz C., et al. The developmental neurobiology of autism spectrum disorder. J Neurosci 26 (2006) 6897-6906
23. Ferguson J.N., Young L.J., Hearn E.F., Matzuk M.M., Insel T.R., and Winslow J.T. Social amnesia in mice lacking the oxytocin gene. Nat Genet 25 (2000) 284-288
24. Folstein S., and Rutter M. Genetic influences and infantile autism. Nature 265 (1977) 726-728
25. Folstein S.E., and Rosen-Sheidley B. Genetics of autism: complex aetiology for a heterogeneous disorder. Nat Rev Genet 2 (2001) 943-955
26. Fombonne E. Epidemiological surveys of autism and other pervasive developmental disorders: an update. J Autism Dev Disord 33 (2003) 365-382
27. Gerlai J., and Gerlai R. Autism: a large unmet medical need and a complex research problem. Physiol Behav 79 (2003) 461-470
28. Hardan A.Y., Minshew N.J., and Keshavan M.S. Corpus callosum size in autism. Neurology 55 (2000) 1033-1036
29. Insel T.R. Mouse models for autism: report from a meeting. Mamm Genome 12 (2001) 755-757
30. Kanner L. Autistic disturbance of affective contact. Nerv Child 2 (1943) 217-250
31. Korvatska E., Van de Water J., Anders T.F., and Gershwin M.E. Genetic and immunologic considerations in autism. Neurobiol Dis 9 (2002) 107-125
32. Kusek G K, Wahlsten D, Herron B J, Bolivar V J, Flaherty L,. Localization of two new X-linked quantitative trait loci controlling corpus callosum size in the mouse, Genes Brain Behav. (in press).
33. Lamb J.A., Moore J., Bailey A., and Monaco A.P. Autism: recent molecular genetic advances. Hum Mol Genet 9 (2000) 861-868
34. Lijam N., Paylor R., McDonald M.P., Crawley J.N., Deng C.X., Herrup K., et al. Social interaction and sensorimotor gating abnormalities in mice lacking Dvl1. Cell 90 (1997) 895-905
35. Long J.M., LaPorte P., Paylor R., and Wynshaw-Boris A. Expanded characterization of the social interaction abnormalities in mice lacking Dvl1. Genes Brain Behav 3 (2004) 51-62
36. Maestrini E., Paul A., Monaco A.P., and Bailey A. Identifying autism susceptibility genes. Neuron 28 (2000) 19-24
37. McFadyen M.P., Kusek G., Bolivar V.J., and Flaherty L. Differences among eight inbred strains of mice in motor ability and motor learning on a rotorod. Genes Brain Behav 2 (2003) 214-219
38. McFarlane HG, Kusek GK, Yang M, Phoenix JL, Bolivar VJ, Crawley JN, Autism-like behaviors in BTBR T + tf/J mice, (in preparation).
39. Mineur Y.S., Huynh L.X., and Crusio W.E. Social behavior deficits in the Fmr1 mutant mouse. Behav Brain Res 168 (2006) 172-175
40. Moy S.S., Nadler J.J., Magnuson T.R., and Crawley J.N. Mouse models of autism spectrum disorders: the challenge for behavior genetics. Am J Med Genet 142C (2006) 40-51
41. Moy S.S., Nadler J.J., Perez A., Barbaro R.P., Johns J.M., Magnuson T.R., et al. Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice. Genes Brain Behav 3 (2004) 287-302
42. Moy SS, Nadler JJ, Young NB, Perez A, Hollowoy LP, Barbaro RP, et al. Mouse behavioral tasks relevant to autism: phenotypes of ten inbred strains, Behav Brain Res, this volume (2006).
43. Nadler J.J., Moy S.S., Dold G., Trang D., Simmons N., Perez A., et al. Automated apparatus for quantitation of social approach behaviors in mice. Genes Brain Behav 3 (2004) 303-314
44. Nicolson R., and Szatmari P. Genetic and neurodevelopmental influences in autistic disorder. Can J Psychiatr 48 (2003) 526-537
45. Parmigiani S., Brain P.F., and Palanza P. Ethoexperimental analysis of different forms of intraspecific aggression in the house mouse (Mus musculus). In: Blanchard R.J., Brain P.F., Blanchard D.C., and Parmigiani S. (Eds). Ethoexperimental approaches to the study of behavior (1989), Kluwer Academic Publishers, Dordrechi 418-431
46. Powers M.D. Children with autism: a parents' guide (2000), Woodbine House, Bethesda
47. Roubertoux P.L., LeRoy I., Mortaud S., Perez-Diaz F., and Tordjman S. Measuring aggression in the mouse. In: Crusio W.E., and Gerlai R.T. (Eds). Handbook of molecular-genetic techniques for brain and behavior research (1999), Elsevier, Amsterdam 696-709
48. Rustay N.R., Wahlsten D., and Crabbe J.C. Assessment of genetic susceptibility to ethanol intoxication in mice. Proc Natl Acad Sci 100 (2003) 2917-2922
49. Salinger W.L., Ladrow P., and Wheeler C. Behavioral phenotype of the reeler mutant mouse: effects of Reln gene dosage and social isolation. Behav Neurosci 117 (2003) 1257-1275
50. Sankoorikal G.M.V., Kaercher K.A., Boon C.J., Lee J.K., and Brodkin E.S. A mouse model system for genetic analysis of sociability: C57BL/6J versus BALB/cJ inbred mouse strains. Biol Psychiatry 59 (2006) 415-423
51. Seong E., Seasholtz A.F., and Burmeister M. Mouse models for psychiatric disorders. Trends Genet 18 (2002) 643-650
52. Shedlovsky A., McDonald J.D., Symula D., and Dove W.F. Mouse models of human phenylketonuria. Genetics 134 (1993) 1205-1210
53. Sweeten T.L., Posey D.J., Shekhar A., and McDougle C.J. The amygdala and related structures in the pathophysiology of autism. Pharmacol Biochem Behav 71 (2002) 449-455
54. Vidal C.N., Nicolson R., DeVito T.J., Hayashi K.M., Geaga J.A., Drosts D.J., et al. Mapping corpus callosum deficits in autism: an index of aberrant cortical connectivity. Biol Psychiatry 60 (2006) 218-225
55. Wahlsten D., Metten P., and Crabbe J.C. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res 971 (2003) 47-54
56. Wing L., and Potter D. The epidemiology of autistic spectrum disorders: is the prevalence rising?. Ment Retard Dev Disabil Res Rev 8 (2002) 151-161