Automated three-chambered social approach task for mice

Current Protocols in Neuroscience

Volumn , Issue SUPPL. 56, 2011, Pages

  Yang, Mu ^a   Silverman, Jill L ^a   Crawley, Jacqueline N ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Autism; Automated behavioral test; Mouse models; Sociability; Social approach; Social behaviors; Three chambered task

Indexed keywords

ACCLIMATIZATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSOCIATION; AUDITORY STIMULATION; AUTISM; CLINICAL PROTOCOL; CONTROLLED STUDY; EQUIPMENT; EXPERIMENTAL STUDY; HABITUATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMELLING; SOCIAL BEHAVIOR; SOCIAL INTERACTION; SOCIAL PARTICIPATION; VISUAL STIMULATION;

EID: 84255209293     PISSN: 19348584     EISSN: 19348576     Source Type: Journal    
DOI: 10.1002/0471142301.ns0826s56     Document Type: Article

References (63)

1. Ahern, T.H., Modi, M.E., Burkett, J.P., and Young, L.J. 2009. Evaluation of two automated metrics for analyzing partner preference tests. J. Neurosci. Methods 182:180-188.
2. American Psychiatric Association. 1994. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). Washington, D.C.
3. Arakawa, H., Arakawa, K., Blanchard, D.C., and Blanchard, R.J. 2008. A new test paradigm for social recognition evidenced by urinary scent marking behavior in C57BL/6J mice. Behav. Brain Res. 190:97-104.
4. Ayadi, A., Ferrand, G., Goncalves da Cruz, I., and Xavier Warot, X. 2011. Mouse breeding and colony management. Curr. Protoc. Mouse Biol. 1:239-264.
5. Bolivar, V.J., Walters, S.R., and Phoenix, J.L. 2007. Assessing autism-like behavior in mice: variations in social interactions among inbred strains. Behav. Brain Res. 176:21-26.
6. Bouet, V., Lecrux, B., Tran, G., and Freret, T. 2011. Effect of pre- versus post-weaning environmental disturbances on social behaviour in mice. Neurosci. Lett. 488:221-224.
7. Branchi, I., Santucci, D., and Alleva, E. 2001. Ultrasonic vocalisation emitted by infant rodents: A tool for assessment of neurobehavioural development. Behav. Brain Res. 125:49-56.
8. Brodkin, E.S., Hagemann, A., Nemetski, S.M., and Silver, L.M. 2004. Social approach-avoidance behavior of inbred mouse strains towardsDBA/2 mice. Brain Res. 1002:151-157.
9. Chadman, K.K. 2011. Fluoxetine but not risperidone increases sociability in the BTBR mouse model of autism. Pharmacol. Biochem. Behav. 97:586-594.
10. Chadman, K.K., Gong, S., Scattoni, M.L., Boltuck, S.E., Gandhy, S.U., Heintz, N., and Crawley, J.N. 2008. Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Res. 1:147-158.
11. Crawley, J.N. 2004. Designing mouse behavioral tasks relevant to autistic-like behaviors. Ment. Retard. Dev. Disabil. Res. Rev. 10:248-258.
12. Crawley, J. 2007a.What'sWrongWith My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice, Second Ed. JohnWiley&Sons, Hoboken, New Jersey.
13. Crawley, J.N. 2007b. Mouse behavioral assays relevant to the symptoms of autism. Brain Pathol. 17:448-459.
14. Crawley, J.N. 2008. Behavioral phenotyping strategies for mutant mice. Neuron 57:809-818.
15. Crawley, J.N., Chen, T., Puri, A., Washburn, R., Sullivan, T.L., Hill, J.M., Young, N.B., Nadler, J.J., Moy, S.S., Young, L.J., Caldwell, H.K., and Young, W.S. 2007. Social approach behaviors in oxytocin knockout mice: Comparison of two independent lines tested in different laboratory environments. Neuropeptides 41:145-163.
16. D'Amato, F.R. and Populin, R. 1987. Motheroffspring interaction and pup development in genetically deaf mice. Behav. Genet. 17:465-475.
17. +tf/J mice. Behav. Brain Res. 217:302-308.
18. DeLorey, T.M., Sahbaie, P., Hashemi, E., Homanics, G.E., and Clark, J.D. 2008. Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: A potential model of autism spectrum disorder. Behav. Brain Res. 187:207-220.
19. Duncan, G.E., Moy, S.S., Perez, A., Eddy, D.M., Zinzow, W.M., Lieberman, J.A., Snouwaert, J.N., and Koller, B.H. 2004. Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function. Behav. Brain Res. 153:507-519.
20. Ehninger, D., Sano, Y., de Vries, P.J., Dies, K., Franz, D., Geschwind, D.H., Kaur, M., Lee, Y.S., Li, W., Lowe, J.K., Nakagawa, J.A., Sahin, M., Smith, K., Whittemore, V., and Silva, A.J. 2010. Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice. Mol. Psychiatry [Epub ahead of print].
21. Hamilton, S.M., Spencer, C.M., Harrison, W.R., Yuva-Paylor, L.A., Graham, D.F., Daza, R.A., Hevner, R.F., Overbeek, P.A., and Paylor, R. 2011. Multiple autism-like behaviors in a novel transgenic mouse model. Behav. Brain Res. 218:29-41.
22. Holmes, A., Lit, Q., Murphy, D.L., Gold, E., and Crawley, J.N. 2003. Abnormal anxiety-related behavior in serotonin transporter null mutant mice: The influence of genetic background. Genes Brain Behav. 2:365-380.
23. Hurst, J.L., Payne, C.E., Nevison, C.M., Marie, A.D., Humphries, R.E., Robertson, D.H., Cavaggioni, A., and Beynon, R.J. 2001. Individual recognition in mice mediated by major urinary proteins. Nature 414:631-634.
24. Jamain, S., Radyushkin, K., Hammerschmidt, K., Granon, S., Boretius, S., Varoqueaux, F., Ramanantsoa, N., Gallego, J., Ronnenberg, A., Winter, D., Frahm, J., Fischer, J., Bourgeron, T., Ehrenreich, H., and Brose, N. 2008. Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proc. Natl. Acad. Sci. U.S.A. 105:1710-1715.
25. Kaidanovich-Beilin, O., Lipina, T., Vukobradovic, I., Roder, J., and Woodgett, J.R. 2011. Assessment of social interaction behaviors. J. Vis. Exp. 25:48.
26. Kavaliers, M., Choleris, E., Agmo, A., Braun, W.J., Colwell, D.D., Muglia, L.J., Ogawa, S., and Pfaff, D.W. 2006. Inadvertent social information and the avoidance of parasitized male mice: Arole for oxytocin. Proc. Natl. Acad. Sci.U.S.A. 103:4293-4298.
27. Kercmar, J., Budefeld, T., Grgurevic, N., Tobet, S.A., and Majdic, G. 2011. Adolescent social isolation changes social recognition in adult mice. Behav. Brain Res. 216:647-651.
28. Koike, H., Ibi, D., Mizoguchi, H., Nagai, T., Nitta, A., Takuma, K., Nabeshima, T., Yoneda, Y., and Yamada, K. 2009. Behavioral abnormality and pharmacologic response in social isolationreared mice. Behav. Brain Res. 202:114-121.
29. Laviola, G. and Terranova, M.L. 1998. The developmental psychobiology of behavioural plasticity in mice: The role of social experiences in the family unit. Neurosci. Biobehav. Rev. 23:197-213.
30. Lord, C. and Bishop, S.L. 2009. The autism spectrum: Definitions, assessment and diagnoses. Br. J. Hosp. Med. (London) 70:132-135.
31. Lord, C., Risi, S., DiLavore, P.S., Shulman, C., Thurm, A., and Pickles, A. 2006. Autism from 2 to 9 years of age. Arch. Gen. Psychiatry 63:694-701.
32. Matsuo, N., Tanda, K., Nakanishi, K., Yamasaki, N., Toyama, K., Takao, K., Takeshima, H., and Miyakawa, T. 2009. Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice: Decreased social contact duration in two social interaction tests. Front. Behav. Neurosci. 3:3.
33. +tf/J mice. Genes Brain Behav. 7:152-163.
34. Miczek, K.A., Maxson, S.C., Fish, E.W., and Faccidomo, S. 2001. Aggressive behavioral phenotypes in mice. Behav. Brain Res. 125:167-181.
35. Moles, A. and D'Amato, F.R. 2000. Ultrasonic vocalization by female mice in the presence of a conspecific carrying food cues. Animal Behav. 60:689-694.
36. Molina, J., Carmona-Mora, P., Chrast, J., Krall, P.M., Canales, C.P., Lupski, J.R., Reymond, A., and Walz, K. 2008. Abnormal social behaviors and altered gene expression rates in a mouse model for Potocki-Lupski syndrome. Hum. Mol. Genet. 17:2486-2495.
37. Moy, S.S., Nadler, J.J., Perez, A., Barbaro, R.P., Johns, J.M., Magnuson, T.R., Piven, J., and Crawley, J.N. 2004. Sociability and preference for social novelty in five inbred strains: An approach to assess autistic-like behavior in mice. Genes Brain Behav. 3:287-302.
38. Moy, S.S., Nadler, J.J., Young, N.B., Perez, A., Holloway, L.P., Barbaro, R.P., Barbaro, J.R., Wilson, L.M., Threadgill, D.W., Lauder, J.M., Magnuson, T.R., and Crawley, J.N. 2007. Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains. Behav. Brain Res. 176:4-20.
39. Moy, S.S., Nadler, J.J., Poe, M.D., Nonneman, R.J., Young, N.B., Koller, B.H., Crawley, J.N., Duncan, G.E., and Bodfish, J.W. 2008a. Development of a mouse test for repetitive, restricted behaviors: Relevance to autism. Behav. Brain Res. 188:178-194.
40. Moy, S.S., Nadler, J.J., Young, N.B., Nonneman, R.J., Segall, S.K., Andrade, G.M., Crawley, J.N., and Magnuson, T.R. 2008b. Social approach and repetitive behavior in eleven inbred mouse strains. Behav. Brain Res. 191:118-129.
41. Moy, S.S., Nadler, J.J., Young, N.B., Nonneman, R.J., Grossman, A.W., Murphy, D.L., D'Ercole, A.J., Crawley, J.N., Magnuson, T.R., and Lauder, J.M. 2009. Social approach in genetically engineered mouse lines relevant to autism. Genes Brain Behav. 8:129-142.
42. Nadler, J.J., Moy, S.S., Dold, G., Trang, D., Simmons, N., Perez, A., Young, N.B., Barbaro, R.P., Piven, J., Magnuson, T.R., and Crawley, J.N. 2004. Automated apparatus for quantitation of social approach behaviors in mice. Genes Brain Behav. 3:303-314.
43. Nakatani, J., Tamada, K., Hatanaka, F., Ise, S., Ohta, H., Inoue, K., Tomonaga, S., Watanabe, Y., Chung, Y.J., Banerjee, R., Iwamoto, K., Kato, T., Okazawa, M., Yamauchi, K., Tanda, K., Takao, K., Miyakawa, T., Bradley, A., and Takumi, T. 2009. Abnormal behavior in a chromosomeengineered mouse model for human 15q11-13 duplication seen in autism. Cell 137:1235-1246.
44. Page, D.T., Kuti, O.J., Prestia, C., and Sur, M. 2009. Haploinsufficiency for Pten and serotonin transporter cooperatively influences brain size and social behavior. Proc. Natl. Acad. Sci. U.S.A. 106:1989-1994.
45. Panksepp, J.B. and Lahvis, G.P. 2007. Social reward among juvenile mice. Genes Brain Behav. 6:661-671.
46. Panksepp, J.B., Jochman, K.A., Kim, J.U., Koy, J.J., Wilson, E.D., Chen, Q., Wilson, C.R., and Lahvis, G.P. 2007. Affiliative behavior, ultrasonic communication and social reward are influenced by genetic variation in adolescentmice. PLoS ONE 2:e351.
47. Radyushkin, K., Hammerschmidt, K., Boretius, S., Varoqueaux, F., El-Kordi, A., Ronnenberg, A., Winter, D., Frahm, J., Fischer, J., Brose, N., and Ehrenreich, H. 2009. Neuroligin-3-deficient mice: Model of a monogenic heritable form of autism with an olfactory deficit. Genes Brain Behav. 8:416-425.
48. Rawleigh, J.M., Kemble, E.D., and Ostrem, J. 1993. Differential effects of prior dominance or subordination experience on conspecific odor preferences in mice. Physiol. Behav. 54:35-39.
49. Rodgers, R.J., Boullier, E., Chatzimichalaki, P., Cooper, G.D., and Shorten, A. 2002. Contrasting phenotypes of C57BL/6JOlaHsd, 129S2/SvHsd and 129/SvEv mice in two exploration-based tests of anxiety-related behaviour. Physiol. Behav. 77:301-310.
50. Ryan, B.C., Young, N.B., Moy, S.S., and Crawley, J.N. 2008. Olfactory cues are sufficient to elicit social approach behaviors but not social transmission of food preference in C57BL/6J mice. Behav. Brain Res. 193:235-242.
51. Silverman, J.L., Tolu, S.S., Barkan, C.L., and Crawley, J.N. 2010a. Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. Neuropsychopharmacology 35:976-989.
52. Silverman, J.L., Yang, M., Lord, C., and Crawley, J.N. 2010b. Behavioural phenotyping assays for mouse models of autism. Nat. Rev. Neurosci. 11:490-502.
53. +)tf/J mouse model of autism. Neuroscience 171:1197-1208.
54. Silverman, J.L., Turner, S.M., Barkan, C.L., Tolu, S.S., Saxena, R., Hung, A.Y., Sheng, M., and Crawley, J.N. 2011. Sociability and motor functions in Shank1 mutant mice. Brain Res. 1380:120-137.
55. Winslow, J.T. 2003. Mouse social recognition and preference. Curr. Protoc. Neurosci. 22:8.16.1-8.16.16.
56. +tf/J, C57BL/6J, and vasopressin receptor 1B mutant mice. Front. Behav. Neurosci. 1:1.
57. +tf/J mice are unchanged by cross-fostering with C57BL/6J mothers. Int. J. Dev. Neurosci. 25:515-521.
58. Yang, M., Weber, M.D., and Crawley, J.N. 2008. Light phase testing of social behaviors: Not a problem. Front. Neurosci. 2:186-191.
59. Yang, M., Clarke, A.M., and Crawley, J.N. 2009. Postnatal lesion evidence against a primary role for the corpus callosum in mouse sociability. Eur. J. Neurosci. 29:1663-1677.
60. Yang, M., Perry, K., Weber, M.D., Katz, A.M., and Crawley, J.N. 2011a. Social peers rescue autismrelevant sociability deficits in adolescent mice. Autism Res. 4:17-27.
61. Yang, M., Scattoni, M.L., Chadman, C.C., Silverman, J.L., and Crawley, J.N. 2011b. Behavioral evaluation of genetic mouse models of autism. In Autism Spectrum Disorders (D. Amaral, D. Geschwind, and G. Dawson, eds.) pp. 904-932. Oxford University Press, New York.
62. Zhao, Y., Fung, C., Shin, D., Shin, B.C., Thamotharan, S., Sankar, R., Ehninger, D., Silva, A., and Devaskar, S.U. 2010. Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders. Mol. Psychiatry 15:286-299.
63. Zhou, J., Blundell, J., Ogawa, S., Kwon, C.H., Zhang, W., Sinton, C., Powell, C.M., and Parada, L.F. 2009. Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. J. Neurosci. 29:1773-1783.