Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: Implications for autism spectrum disorders

Experimental Neurology

Volumn 247, Issue , 2013, Pages 496-505

  Sgadò, Paola ^a   Genovesi, Sacha ^a   Kalinovsky, Anna ^b   Zunino, Giulia ^a   Macchi, Francesca ^c,d   Allegra, Manuela ^c   Murenu, Elisa ^a,e   Provenzano, Giovanni ^a   Tripathi, Prem Prakash ^c,f   Casarosa, Simona ^a,c   Joyner, Alexandra L ^b   Bozzi, Yuri ^a,c  

^a UNIVERSITY OF TRENTO   (Italy)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c CNR   (Italy)

^d UNIVERSITY OF LEUVEN   (Belgium)

^e UNIVERSITY OF MUNICH   (Germany)

^f EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

Author keywords

Homeobox transcription factor; Inhibition; Interneuron; Neurodevelopmental disorder; Parvalbumin

Indexed keywords

BIOLOGICAL MARKER; ENGRAILED 2 PROTEIN; MESSENGER RNA; NEUROPEPTIDE Y; PARVALBUMIN; SOMATOSTATIN; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; BRAIN NERVE CELL; BRAIN REGION; CELL LOSS; CELL POPULATION; CONTROLLED STUDY; ENGRAILED 2 GENE; FEMALE; GABAERGIC SYSTEM; GENE EXPRESSION; GENE INACTIVATION; GENE TARGETING; GENOTYPE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; INTERNEURON; MALE; MARKER GENE; MOLECULAR PATHOLOGY; MOUSE; NEUROANATOMY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATOSENSORY CORTEX;

Γ-AMINOBUTYRIC ACID; ASD; AUTISM SPECTRUM DISORDERS; CALB; CALBINDIN 28KD; CCK; CHOLECYSTOKIN; DENTATE GYRUS; DG; EN2; ENGRAILED-2; GABA; GAD; GLUTAMIC ACID DECARBOXYLASE; HOMEOBOX TRANSCRIPTION FACTOR; INHIBITION; INTERNEURON; NEURODEVELOPMENTAL DISORDER; NEUROPEPTIDE Y; NPY; PARVALBUMIN; PV; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RT-PCR; SINGLE-NUCLEOTIDE POLYMORPHISM; SNP; SOM; SOMATOSTATIN; VASOINTESTINAL PEPTIDE; VESICULAR GABA TRANSPORTER; VESICULAR GLUTAMATE TRANSPORTER; VGAT; VGLUT; VIP;

ANIMALS; AUTISTIC DISORDER; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GABAERGIC NEURONS; HIPPOCAMPUS; HOMEODOMAIN PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEUROPEPTIDE Y; PARVALBUMINS; SOMATOSTATIN;

EID: 84881378088     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.01.021     Document Type: Article

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