High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 28, 2015, Pages 8714-8719

  Wall, Christopher E ^a,b   Whyte, Jamie ^a   Suh, Jae M ^a   Fan, Weiwei ^a   Collins, Brett ^a   Liddle, Christopher ^c   Yu, Ruth T ^a   Atkins, Annette R ^a   Naviaux, Jane C ^d   Li, Kefeng ^d   Bright, Andrew Taylor ^d   Alaynick, William A ^d   Downes, Michael ^a   Naviaux, Robert K ^d,e   Evans, Ronald M ^a,f  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WESTMEAD HOSPITAL   (Australia)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Brown fat; FGF21; Mitochondria; Polymerase gamma; Thermogenesis

Indexed keywords

FIBROBLAST GROWTH FACTOR 21; MITOCHONDRIAL DNA; FIBROBLAST GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DIET INDUCED OBESITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE MUTATION; LIPID DIET; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; STARVATION; THERMOGENESIS; AEROBIC METABOLISM; ANIMAL; GENETICS; METABOLISM; MUTANT MOUSE STRAIN; PHYSIOLOGY;

MUS;

ADIPOSE TISSUE, BROWN; AEROBIOSIS; ANIMALS; DIET, HIGH-FAT; FIBROBLAST GROWTH FACTORS; MALE; MICE; MICE, MUTANT STRAINS; MITOCHONDRIA; THERMOGENESIS;

EID: 84937137980     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1509930112     Document Type: Article

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