-
1
-
-
3242866272
-
Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication
-
M. Albring, J. Griffith, and G. Attardi Association of a protein structure of probable membrane derivation with HeLa cell mitochondrial DNA near its origin of replication Proc. Natl. Acad. Sci. USA 74 1977 1348 1352
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 1348-1352
-
-
Albring, M.1
Griffith, J.2
Attardi, G.3
-
2
-
-
65549121567
-
Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA
-
L.J. Bailey, T.J. Cluett, A. Reyes, T.A. Prolla, J. Poulton, C. Leeuwenburgh, and I.J. Holt Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA Nucleic Acids Res. 37 2009 2327 2335
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 2327-2335
-
-
Bailey, L.J.1
Cluett, T.J.2
Reyes, A.3
Prolla, T.A.4
Poulton, J.5
Leeuwenburgh, C.6
Holt, I.J.7
-
3
-
-
55549089660
-
Accurate whole human genome sequencing using reversible terminator chemistry
-
D.R. Bentley, S. Balasubramanian, H.P. Swerdlow, G.P. Smith, J. Milton, C.G. Brown, K.P. Hall, D.J. Evers, C.L. Barnes, and H.R. Bignell Accurate whole human genome sequencing using reversible terminator chemistry Nature 456 2008 53 59
-
(2008)
Nature
, vol.456
, pp. 53-59
-
-
Bentley, D.R.1
Balasubramanian, S.2
Swerdlow, H.P.3
Smith, G.P.4
Milton, J.5
Brown, C.G.6
Hall, K.P.7
Evers, D.J.8
Barnes, C.L.9
Bignell, H.R.10
-
4
-
-
0027230737
-
A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies
-
M. Brockington, M.G. Sweeney, S.R. Hammans, J.A. Morgan-Hughes, and A.E. Harding A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies Nat. Genet. 4 1993 67 71
-
(1993)
Nat. Genet.
, vol.4
, pp. 67-71
-
-
Brockington, M.1
Sweeney, M.G.2
Hammans, S.R.3
Morgan-Hughes, J.A.4
Harding, A.E.5
-
5
-
-
26944500840
-
Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism
-
T.A. Brown, C. Cecconi, A.N. Tkachuk, C. Bustamante, and D.A. Clayton Replication of mitochondrial DNA occurs by strand displacement with alternative light-strand origins, not via a strand-coupled mechanism Genes Dev. 19 2005 2466 2476
-
(2005)
Genes Dev.
, vol.19
, pp. 2466-2476
-
-
Brown, T.A.1
Cecconi, C.2
Tkachuk, A.N.3
Bustamante, C.4
Clayton, D.A.5
-
6
-
-
68049115765
-
Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice
-
D. Edgar, I. Shabalina, Y. Camara, A. Wredenberg, M.A. Calvaruso, L. Nijtmans, J. Nedergaard, B. Cannon, N.G. Larsson, and A. Trifunovic Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice Cell Metab. 10 2009 131 138
-
(2009)
Cell Metab.
, vol.10
, pp. 131-138
-
-
Edgar, D.1
Shabalina, I.2
Camara, Y.3
Wredenberg, A.4
Calvaruso, M.A.5
Nijtmans, L.6
Nedergaard, J.7
Cannon, B.8
Larsson, N.G.9
Trifunovic, A.10
-
7
-
-
72649099157
-
Response: Point Mutations Are Causing Progeroid Phenotypes in the mtDNA Mutator Mouse
-
D. Edgar, N.G. Larsson, and A. Trifunovic Response: Point Mutations Are Causing Progeroid Phenotypes in the mtDNA Mutator Mouse Cell Metab. 11 2010 93
-
(2010)
Cell Metab.
, vol.11
, pp. 93
-
-
Edgar, D.1
Larsson, N.G.2
Trifunovic, A.3
-
8
-
-
61849118621
-
Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons
-
H. Fukui, and C.T. Moraes Mechanisms of formation and accumulation of mitochondrial DNA deletions in aging neurons Hum. Mol. Genet. 18 2009 1028 1036
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 1028-1036
-
-
Fukui, H.1
Moraes, C.T.2
-
9
-
-
77950083955
-
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
-
Y. He, J. Wu, D.C. Dressman, C. Iacobuzio-Donahue, S.D. Markowitz, V.E. Velculescu, L.A. Diaz Jr., K.W. Kinzler, B. Vogelstein, and N. Papadopoulos Heteroplasmic mitochondrial DNA mutations in normal and tumour cells Nature 464 2010 610 614
-
(2010)
Nature
, vol.464
, pp. 610-614
-
-
He, Y.1
Wu, J.2
Dressman, D.C.3
Iacobuzio-Donahue, C.4
Markowitz, S.D.5
Velculescu, V.E.6
Diaz Jr., L.A.7
Kinzler, K.W.8
Vogelstein, B.9
Papadopoulos, N.10
-
10
-
-
0035942104
-
The 3′ - >5′ exonuclease of DNA polymerase delta can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability
-
Y.H. Jin, R. Obert, P.M. Burgers, T.A. Kunkel, M.A. Resnick, and D.A. Gordenin The 3′ - >5′ exonuclease of DNA polymerase delta can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability Proc. Natl. Acad. Sci. USA 98 2001 5122 5127
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5122-5127
-
-
Jin, Y.H.1
Obert, R.2
Burgers, P.M.3
Kunkel, T.A.4
Resnick, M.A.5
Gordenin, D.A.6
-
11
-
-
0035851098
-
Exonuclease proofreading by human mitochondrial DNA polymerase
-
A.A. Johnson, and K.A. Johnson Exonuclease proofreading by human mitochondrial DNA polymerase J. Biol. Chem. 276 2001 38097 38107
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38097-38107
-
-
Johnson, A.A.1
Johnson, K.A.2
-
12
-
-
33745712834
-
Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes
-
T. Kasahara, M. Kubota, T. Miyauchi, Y. Noda, A. Mouri, T. Nabeshima, and T. Kato Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes Mol. Psychiatry 11 2006 577 593
-
(2006)
Mol. Psychiatry
, vol.11
, pp. 577-593
-
-
Kasahara, T.1
Kubota, M.2
Miyauchi, T.3
Noda, Y.4
Mouri, A.5
Nabeshima, T.6
Kato, T.7
-
13
-
-
1542677230
-
TWINKLE Has 5′ -> 3′ DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein
-
J.A. Korhonen, M. Gaspari, and M. Falkenberg TWINKLE Has 5′ -> 3′ DNA helicase activity and is specifically stimulated by mitochondrial single-stranded DNA-binding protein J. Biol. Chem. 278 2003 48627 48632
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48627-48632
-
-
Korhonen, J.A.1
Gaspari, M.2
Falkenberg, M.3
-
14
-
-
67651177611
-
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
-
Y. Kraytsberg, D.K. Simon, D.M. Turnbull, and K. Khrapko Do mtDNA deletions drive premature aging in mtDNA mutator mice? Aging Cell 8 2009 502 506
-
(2009)
Aging Cell
, vol.8
, pp. 502-506
-
-
Kraytsberg, Y.1
Simon, D.K.2
Turnbull, D.M.3
Khrapko, K.4
-
15
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
G.C. Kujoth, A. Hiona, T.D. Pugh, S. Someya, K. Panzer, S.E. Wohlgemuth, T. Hofer, A.Y. Seo, R. Sullivan, and W.A. Jobling Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging Science 309 2005 481 484
-
(2005)
Science
, vol.309
, pp. 481-484
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
-
16
-
-
0028948888
-
High levels of mitochondrial DNA with an unstable 260-bp duplication in a patient with a mitochondrial myopathy
-
G. Manfredi, S. Servidei, E. Bonilla, S. Shanske, E.A. Schon, S. DiMauro, and C.T. Moraes High levels of mitochondrial DNA with an unstable 260-bp duplication in a patient with a mitochondrial myopathy Neurology 45 1995 762 768
-
(1995)
Neurology
, vol.45
, pp. 762-768
-
-
Manfredi, G.1
Servidei, S.2
Bonilla, E.3
Shanske, S.4
Schon, E.A.5
Dimauro, S.6
Moraes, C.T.7
-
17
-
-
67651205866
-
Pathological replication in cells lacking RecG DNA translocase
-
C.J. Rudolph, A.L. Upton, L. Harris, and R.G. Lloyd Pathological replication in cells lacking RecG DNA translocase Mol. Microbiol. 73 2009 352 366
-
(2009)
Mol. Microbiol.
, vol.73
, pp. 352-366
-
-
Rudolph, C.J.1
Upton, A.L.2
Harris, L.3
Lloyd, R.G.4
-
18
-
-
70449560624
-
Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase
-
C.J. Rudolph, A.L. Upton, and R.G. Lloyd Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase Mol. Microbiol. 74 2009 940 955
-
(2009)
Mol. Microbiol.
, vol.74
, pp. 940-955
-
-
Rudolph, C.J.1
Upton, A.L.2
Lloyd, R.G.3
-
19
-
-
54949116516
-
Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse
-
P. Sachadyn, X.M. Zhang, L.D. Clark, R.K. Naviaux, and E. Heber-Katz Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse Mitochondrion 8 2008 358 366
-
(2008)
Mitochondrion
, vol.8
, pp. 358-366
-
-
Sachadyn, P.1
Zhang, X.M.2
Clark, L.D.3
Naviaux, R.K.4
Heber-Katz, E.5
-
20
-
-
18344385508
-
Protein - Protein interactions in the eubacterial replisome
-
P.M. Schaeffer, M.J. Headlam, and N.E. Dixon Protein - protein interactions in the eubacterial replisome IUBMB Life 57 2005 5 12
-
(2005)
IUBMB Life
, vol.57
, pp. 5-12
-
-
Schaeffer, P.M.1
Headlam, M.J.2
Dixon, N.E.3
-
21
-
-
38949091096
-
Strong purifying selection in transmission of mammalian mitochondrial DNA
-
J.B. Stewart, C. Freyer, J.L. Elson, A. Wredenberg, Z. Cansu, A. Trifunovic, and N.G. Larsson Strong purifying selection in transmission of mammalian mitochondrial DNA PLoS Biol. 6 2008 e10
-
(2008)
PLoS Biol.
, vol.6
, pp. 10
-
-
Stewart, J.B.1
Freyer, C.2
Elson, J.L.3
Wredenberg, A.4
Cansu, Z.5
Trifunovic, A.6
Larsson, N.G.7
-
22
-
-
0028095263
-
MtDNA and the origin of Caucasians: Identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region
-
A. Torroni, M.T. Lott, M.F. Cabell, Y.S. Chen, L. Lavergne, and D.C. Wallace mtDNA and the origin of Caucasians: identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region Am. J. Hum. Genet. 55 1994 760 776
-
(1994)
Am. J. Hum. Genet.
, vol.55
, pp. 760-776
-
-
Torroni, A.1
Lott, M.T.2
Cabell, M.F.3
Chen, Y.S.4
Lavergne, L.5
Wallace, D.C.6
-
23
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
A. Trifunovic, A. Wredenberg, M. Falkenberg, J.N. Spelbrink, A.T. Rovio, C.E. Bruder, M. Bohlooly-Y, S. Gidlöf, A. Oldfors, and R. Wibom Premature ageing in mice expressing defective mitochondrial DNA polymerase Nature 429 2004 417 423
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly-Y, M.7
Gidlöf, S.8
Oldfors, A.9
Wibom, R.10
-
24
-
-
29144486726
-
Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice
-
H. Tyynismaa, K.P. Mjosund, S. Wanrooij, I. Lappalainen, E. Ylikallio, A. Jalanko, J.N. Spelbrink, A. Paetau, and A. Suomalainen Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice Proc. Natl. Acad. Sci. USA 102 2005 17687 17692
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17687-17692
-
-
Tyynismaa, H.1
Mjosund, K.P.2
Wanrooij, S.3
Lappalainen, I.4
Ylikallio, E.5
Jalanko, A.6
Spelbrink, J.N.7
Paetau, A.8
Suomalainen, A.9
-
25
-
-
76249100243
-
Next generation sequence analysis for mitochondrial disorders
-
V. Vasta, S.B. Ng, E.H. Turner, J. Shendure, and S.H. Hahn Next generation sequence analysis for mitochondrial disorders Genome Med. 1 2009 100
-
(2009)
Genome Med.
, vol.1
, pp. 100
-
-
Vasta, V.1
Ng, S.B.2
Turner, E.H.3
Shendure, J.4
Hahn, S.H.5
-
26
-
-
41349087783
-
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice
-
M. Vermulst, J. Wanagat, G.C. Kujoth, J.H. Bielas, P.S. Rabinovitch, T.A. Prolla, and L.A. Loeb DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice Nat. Genet. 40 2008 392 394
-
(2008)
Nat. Genet.
, vol.40
, pp. 392-394
-
-
Vermulst, M.1
Wanagat, J.2
Kujoth, G.C.3
Bielas, J.H.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
27
-
-
70450121949
-
On mitochondria, mutations, and methodology
-
M. Vermulst, J. Wanagat, and L.A. Loeb On mitochondria, mutations, and methodology Cell Metab. 10 2009 437
-
(2009)
Cell Metab.
, vol.10
, pp. 437
-
-
Vermulst, M.1
Wanagat, J.2
Loeb, L.A.3
-
28
-
-
56749180593
-
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes
-
T. Wai, D. Teoli, and E.A. Shoubridge The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes Nat. Genet. 40 2008 1484 1488
-
(2008)
Nat. Genet.
, vol.40
, pp. 1484-1488
-
-
Wai, T.1
Teoli, D.2
Shoubridge, E.A.3
-
29
-
-
0029741620
-
Tandem duplications and large-scale deletions of mitochondrial DNA are early molecular events of human aging process
-
Y.H. Wei, C.Y. Pang, B.J. You, and H.C. Lee Tandem duplications and large-scale deletions of mitochondrial DNA are early molecular events of human aging process Ann. N Y Acad. Sci. 786 1996 82 101
-
(1996)
Ann. N y Acad. Sci.
, vol.786
, pp. 82-101
-
-
Wei, Y.H.1
Pang, C.Y.2
You, B.J.3
Lee, H.C.4
-
30
-
-
0036073133
-
Pattern of organization of human mitochondrial pseudogenes in the nuclear genome
-
M. Woischnik, and C.T. Moraes Pattern of organization of human mitochondrial pseudogenes in the nuclear genome Genome Res. 12 2002 885 893
-
(2002)
Genome Res.
, vol.12
, pp. 885-893
-
-
Woischnik, M.1
Moraes, C.T.2
-
31
-
-
33751088000
-
Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand
-
T. Yasukawa, A. Reyes, T.J. Cluett, M.Y. Yang, M. Bowmaker, H.T. Jacobs, and I.J. Holt Replication of vertebrate mitochondrial DNA entails transient ribonucleotide incorporation throughout the lagging strand EMBO J. 25 2006 5358 5371
-
(2006)
EMBO J.
, vol.25
, pp. 5358-5371
-
-
Yasukawa, T.1
Reyes, A.2
Cluett, T.J.3
Yang, M.Y.4
Bowmaker, M.5
Jacobs, H.T.6
Holt, I.J.7
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