CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination

Nature Communications

Volumn 6, Issue , 2015, Pages

  Marjanović, Marko ^a,b   Sánchez Huertas, Carlos ^a   Terré, Berta ^a   Gómez, Rocío ^c   Scheel, Jan Frederik ^d,h   Pacheco, Sarai ^e   Knobel, Philip A ^a   Martínez Marchal, Ana ^e   Aivio, Suvi ^a   Palenzuela, Lluís ^a   Wolfrum, Uwe ^d   McKinnon, Peter J ^f   Suja, José A ^c   Roig, Ignasi ^e   Costanzo, Vincenzo ^g   Lüders, Jens ^a   Stracker, Travis H ^a  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b RUDER BO KOVI INSTITUTE   (Croatia)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^f ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^g FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^h MAX PLANCK INSTITUTE FOR CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN CEP63; PROTEIN DERIVATIVE; PROTEIN P53; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; CEP63 PROTEIN, MOUSE;

ABNORMALITY; BRAIN; CELLS AND CELL COMPONENTS; CHROMOSOME; DNA; INFERTILITY; INJURY; MALE; MUTATION; PATHOLOGY; PROTEIN; RECOMBINATION; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN SIZE; CELL DEATH; CENTROSOME; CHROMOSOME STRUCTURE; CONTROLLED STUDY; DNA DAMAGE; MALE; MALE INFERTILITY; MEIOTIC RECOMBINATION; MICROCEPHALY; MOUSE; NEURAL STEM CELL; NONHUMAN; PROTEIN DEFICIENCY; SECKEL SYNDROME; SPERMATOCYTE; TELOMERE; ANIMAL; DWARFISM; FACIES; GENETIC RECOMBINATION; GENETICS; HOMOLOGOUS RECOMBINATION; IMMUNOHISTOCHEMISTRY; MEIOSIS; METABOLISM; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SPERMATOZOON COUNT;

MUS;

ANIMALS; CELL CYCLE PROTEINS; CENTROSOME; DNA DAMAGE; DWARFISM; FACIES; HOMOLOGOUS RECOMBINATION; IMMUNOHISTOCHEMISTRY; MALE; MEIOSIS; MICE; MICROCEPHALY; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; SPERM COUNT; SPERMATOCYTES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84937000714     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8676     Document Type: Article

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