-
1
-
-
33745763425
-
Regulation of mitotic entry by microcephalin and its overlap with ATR signalling
-
Alderton GK, Galbiati L, Griffith E, Surinya KH, Neitzel H, Jackson AP et al. (2006). Regulation of mitotic entry by microcephalin and its overlap with ATR signalling. Nat Cell Biol 8: 725-733.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 725-733
-
-
Alderton, G.K.1
Galbiati, L.2
Griffith, E.3
Surinya, K.H.4
Neitzel, H.5
Jackson, A.P.6
-
2
-
-
14844314790
-
The BRCA1 RING and BRCT domains cooperate in targeting BRCA1 to ionizing radiation-induced nuclear foci
-
Au WW, Henderson BR. (2005). The BRCA1 RING and BRCT domains cooperate in targeting BRCA1 to ionizing radiation-induced nuclear foci. J Biol Chem 280: 6993-7001.
-
(2005)
J Biol Chem
, vol.280
, pp. 6993-7001
-
-
Au, W.W.1
Henderson, B.R.2
-
3
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek J, Lukas J. (2003). Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3: 421-429.
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
4
-
-
20144386602
-
A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size
-
Bond J, Roberts E, Springell K, Lizarraga SB, Scott S, Higgins J et al. (2005). A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nat Genet 37: 353-355.
-
(2005)
Nat Genet
, vol.37
, pp. 353-355
-
-
Bond, J.1
Roberts, E.2
Springell, K.3
Lizarraga, S.B.4
Scott, S.5
Higgins, J.6
-
5
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A et al. (2003). Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 5: 675-679.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
-
6
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, Sedelnikova OA et al. (2002). Genomic instability in mice lacking histone H2AX. Science 296: 922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
-
7
-
-
6344285329
-
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM
-
Dodson H, Bourke E, Jeffers LJ, Vagnarelli P, Sonoda E, Takeda S et al. (2004). Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J 23: 3864-3873.
-
(2004)
EMBO J
, vol.23
, pp. 3864-3873
-
-
Dodson, H.1
Bourke, E.2
Jeffers, L.J.3
Vagnarelli, P.4
Sonoda, E.5
Takeda, S.6
-
8
-
-
6344287454
-
Interactions between BRCT repeats and phosphoproteins: Tangled up in two
-
Glover JN, Williams RS, Lee MS. (2004). Interactions between BRCT repeats and phosphoproteins: tangled up in two. Trends Biochem Sci 29: 579-585.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 579-585
-
-
Glover, J.N.1
Williams, R.S.2
Lee, M.S.3
-
9
-
-
32644447023
-
NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
-
Haren L, Remy MH, Bazin I, Callebaut I, Wright M, Merdes A. (2006). NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J Cell Biol 172: 505-515.
-
(2006)
J Cell Biol
, vol.172
, pp. 505-515
-
-
Haren, L.1
Remy, M.H.2
Bazin, I.3
Callebaut, I.4
Wright, M.5
Merdes, A.6
-
10
-
-
0036302105
-
Identification of microcephalin, a protein implicated in determining the size of the human brain
-
Jackson AP, Eastwood H, Bell SM, Adu J, Toomes C, Carr IM et al. (2002). Identification of microcephalin, a protein implicated in determining the size of the human brain. Am J Hum Genet 71: 136-142.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 136-142
-
-
Jackson, A.P.1
Eastwood, H.2
Bell, S.M.3
Adu, J.4
Toomes, C.5
Carr, I.M.6
-
11
-
-
0037821661
-
Multiple tumor suppressor pathways negatively regulate telomerase
-
Lin SY, Elledge SJ. (2003). Multiple tumor suppressor pathways negatively regulate telomerase. Cell 113: 881-889.
-
(2003)
Cell
, vol.113
, pp. 881-889
-
-
Lin, S.Y.1
Elledge, S.J.2
-
12
-
-
27244445051
-
BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly
-
Lin SY, Rai R, Li K, Xu ZX, Elledge SJ. (2005). BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly. Proc Natl Acad Sci USA 102: 15105-15109.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15105-15109
-
-
Lin, S.Y.1
Rai, R.2
Li, K.3
Xu, Z.X.4
Elledge, S.J.5
-
13
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
Manke IA, Lowery DM, Nguyen A, Yaffe MB. (2003). BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 302: 636-639.
-
(2003)
Science
, vol.302
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
14
-
-
0036210178
-
Premature chromosome condensation in humans associated with microcephaly and mental retardation: A novel autosomal recessive condition
-
Neitzel H, Neumann LM, Schindler D, Wirges A, Tonnies H, Trimborn M et al. (2002). Premature chromosome condensation in humans associated with microcephaly and mental retardation: a novel autosomal recessive condition. Am J Hum Genet 70: 1015-1022.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1015-1022
-
-
Neitzel, H.1
Neumann, L.M.2
Schindler, D.3
Wirges, A.4
Tonnies, H.5
Trimborn, M.6
-
15
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM. (2000). A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr Biol 10: 886-895.
-
(2000)
Curr Biol
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
16
-
-
33746857684
-
BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer
-
Rai R, Dai H, Multani AS, Li K, Chin K, Gray J et al. (2006). BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer. Cancer Cell 10: 1-13.
-
(2006)
Cancer Cell
, vol.10
, pp. 1-13
-
-
Rai, R.1
Dai, H.2
Multani, A.S.3
Li, K.4
Chin, K.5
Gray, J.6
-
17
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou EP, Boon C, Redon C, Bonner WM. (1999). Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol 146: 905-916.
-
(1999)
J Cell Biol
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
18
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. (2003). ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 3: 155-168.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
19
-
-
33847340207
-
Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair
-
Sonoda E, Zhao GY, Kohzaki M, Dhar PK, Kikuchi K, Redon C et al. (2007). Collaborative roles of gammaH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair. DNA Repair (Amst) 6: 280-292.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 280-292
-
-
Sonoda, E.1
Zhao, G.Y.2
Kohzaki, M.3
Dhar, P.K.4
Kikuchi, K.5
Redon, C.6
-
20
-
-
0037684805
-
The multiple nuclear functions of BRCA1: Transcription, ubiquitination and DNA repair
-
Starita LM, Parvin JD. (2003). The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr Opin Cell Biol 15: 345-350.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 345-350
-
-
Starita, L.M.1
Parvin, J.D.2
-
21
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, Jackson SP. (2005). MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123: 1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
22
-
-
3242657086
-
Mutations in microcephalin cause aberrant regulation of chromosome condensation
-
Trimborn M, Bell SM, Felix C, Rashid Y, Jafri H, Griffiths PD et al. (2004). Mutations in microcephalin cause aberrant regulation of chromosome condensation. Am J Hum Genet 75: 261-266.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 261-266
-
-
Trimborn, M.1
Bell, S.M.2
Felix, C.3
Rashid, Y.4
Jafri, H.5
Griffiths, P.D.6
-
23
-
-
0042671242
-
BRCA1-independent ubiquitination of FANCD2
-
Vandenberg CJ, Gergely F, Ong CY, Pace P, Mallery DL, Hiom K et al. (2003). BRCA1-independent ubiquitination of FANCD2. Mol Cell 12: 247-254.
-
(2003)
Mol Cell
, vol.12
, pp. 247-254
-
-
Vandenberg, C.J.1
Gergely, F.2
Ong, C.Y.3
Pace, P.4
Mallery, D.L.5
Hiom, K.6
-
24
-
-
4544269236
-
Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1
-
Xu X, Lee J, Stern DF. (2004). Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1. J Biol Chem 279: 34091-34094.
-
(2004)
J Biol Chem
, vol.279
, pp. 34091-34094
-
-
Xu, X.1
Lee, J.2
Stern, D.F.3
-
25
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu X, Chini CC, He M, Mer G, Chen J. (2003). The BRCT domain is a phospho-protein binding domain. Science 302: 639-642.
-
(2003)
Science
, vol.302
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
26
-
-
0037415735
-
Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects
-
Zachos G, Rainey MD, Gillespie DA. (2003). Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J 22: 713-723.
-
(2003)
EMBO J
, vol.22
, pp. 713-723
-
-
Zachos, G.1
Rainey, M.D.2
Gillespie, D.A.3
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