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Volumn 36, Issue 4, 2015, Pages 1563-1576

Stimulation of Wnt/β-Catenin Signaling to Improve Bone Development by Naringin via Interacting with AMPK and Akt

Author keywords

AMP activated protein kinase (AMPK); Lymphoid enhancer factor (LEF) T cell factor (TCF); Naringin; Protein kinase B (Akt); catenin

Indexed keywords

ADENYLATE KINASE; ALKALINE PHOSPHATASE; AURANTIIN; BETA CATENIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; WNT PROTEIN; FLAVANONE DERIVATIVE; MESSENGER RNA; T CELL FACTOR PROTEIN;

EID: 84936935142     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000430319     Document Type: Article
Times cited : (61)

References (56)
  • 1
    • 0022625922 scopus 로고
    • Involutional osteoporosis
    • Riggs BL, Melton LJ, 3rd: Involutional osteoporosis. N Engl J Med 1986;314:1676-1686.
    • (1986) N Engl J Med , vol.314 , pp. 1676-1686
    • Riggs, B.L.1    Melton, L.J.2
  • 2
    • 0028799124 scopus 로고
    • The worldwide problem of osteoporosis: Insights afforded by epidemiology
    • Riggs BL, Melton LJ, 3rd: The worldwide problem of osteoporosis: Insights afforded by epidemiology. Bone 1995;17:505S-511S.
    • (1995) Bone , vol.17 , pp. 505S-511S
    • Riggs, B.L.1    Melton, L.J.2
  • 3
    • 0028188829 scopus 로고
    • Assessment of fracture risk and its application to screening for postmenopausal osteoporosis,Report of a who study group
    • Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a who study group. World Health Organ Tech Rep Ser 1994;843:1-129.
    • (1994) World Health Organ Tech Rep ser , vol.843 , pp. 1-129
  • 6
    • 0036606093 scopus 로고    scopus 로고
    • Diagnosis of osteoporosis and assessment of fracture risk
    • Kanis JA: Diagnosis of osteoporosis and assessment of fracture risk. Lancet 2002;359:1929-1936.
    • (2002) Lancet , vol.359 , pp. 1929-1936
    • Kanis, J.A.1
  • 7
    • 0037474465 scopus 로고    scopus 로고
    • Activated beta-catenin induces osteoblast differentiation of c3h10t1/2 cells and participates in bmp2 mediated signal transduction
    • Bain G, Muller T, Wang X, Papkoff J: Activated beta-catenin induces osteoblast differentiation of c3h10t1/2 cells and participates in bmp2 mediated signal transduction. Biochem Biophys Res Commun 2003;301:84-91.
    • (2003) Biochem Biophys Res Commun , vol.301 , pp. 84-91
    • Bain, G.1    Muller, T.2    Wang, X.3    Papkoff, J.4
  • 8
    • 0142241118 scopus 로고    scopus 로고
    • Bmp-2 controls alkaline phosphatase expression and osteoblast mineralization by a wnt autocrine loop
    • Rawadi G, Vayssiere B, Dunn F, Baron R, Roman-Roman S: Bmp-2 controls alkaline phosphatase expression and osteoblast mineralization by a wnt autocrine loop. J Bone Miner Res 2003;18:1842-1853.
    • (2003) J Bone Miner Res , vol.18 , pp. 1842-1853
    • Rawadi, G.1    Vayssiere, B.2    Dunn, F.3    Baron, R.4    Roman-Roman, S.5
  • 9
    • 0033864484 scopus 로고    scopus 로고
    • Dual roles of wnt signaling during chondrogenesis in the chicken limb
    • Hartmann C, Tabin CJ: Dual roles of wnt signaling during chondrogenesis in the chicken limb. Development 2000;127:3141-3159.
    • (2000) Development , vol.127 , pp. 3141-3159
    • Hartmann, C.1    Tabin, C.J.2
  • 10
    • 84885004730 scopus 로고    scopus 로고
    • Reciprocal interferences of TNF-alpha and wnt1/ beta-catenin signaling axes shift bone marrow-derived stem cells towards osteoblast lineage after ethanol exposure
    • Chen Y, Chen L, Yin Q, Gao H, Dong P, Zhang X, Kang J: Reciprocal interferences of tnf-alpha and wnt1/ beta-catenin signaling axes shift bone marrow-derived stem cells towards osteoblast lineage after ethanol exposure. Cell Physiol Biochem 2013;32:755-765.
    • (2013) Cell Physiol Biochem , vol.32 , pp. 755-765
    • Chen, Y.1    Chen, L.2    Yin, Q.3    Gao, H.4    Dong, P.5    Zhang, X.6    Kang, J.7
  • 11
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of wnt signaling through beta-catenin
    • Moon RT, Bowerman B, Boutros M, Perrimon N: The promise and perils of wnt signaling through beta-catenin. Science 2002;296:1644-1646.
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 12
    • 0033618382 scopus 로고    scopus 로고
    • Regulation of the protein kinase activity of shaggy(zeste-white3) by components of the wingless pathway in drosophila cells and embryos
    • Ruel L, Stambolic V, Ali A, Manoukian AS, Woodgett JR: Regulation of the protein kinase activity of shaggy(zeste-white3) by components of the wingless pathway in drosophila cells and embryos. J Biol Chem 1999;274:21790-21796.
    • (1999) J Biol Chem , vol.274 , pp. 21790-21796
    • Ruel, L.1    Stambolic, V.2    Ali, A.3    Manoukian, A.S.4    Woodgett, J.R.5
  • 14
    • 0037338999 scopus 로고    scopus 로고
    • Armadillo/beta-catenin signals in the nucleus-proof beyond a reasonable doubt
    • Bienz M, Clevers H: Armadillo/beta-catenin signals in the nucleus-proof beyond a reasonable doubt Nat Cell Biol 2003;5:179-182.
    • (2003) Nat Cell Biol , vol.5 , pp. 179-182
    • Bienz, M.1    Clevers, H.2
  • 15
    • 0038485600 scopus 로고    scopus 로고
    • Lymphoid enhancer factor-1 and beta-catenin inhibit runx2-dependent transcriptional activation of the osteocalcin promoter
    • Kahler RA, Westendorf JJ: Lymphoid enhancer factor-1 and beta-catenin inhibit runx2-dependent transcriptional activation of the osteocalcin promoter. J Biol Chem 2003;278:11937-11944.
    • (2003) J Biol Chem , vol.278 , pp. 11937-11944
    • Kahler, R.A.1    Westendorf, J.J.2
  • 16
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle WJ, Simonet WS, Lacey DL: Osteoclast differentiation and activation. Nature 2003;423:337-342.
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 20
    • 33746253640 scopus 로고    scopus 로고
    • Citrus flavonoids in fruit and traditional Chinese medicinal food ingredients in China
    • Lu Y, Zhang C, Bucheli P, Wei D: Citrus flavonoids in fruit and traditional chinese medicinal food ingredients in China. Plant Foods Hum Nutr 2006;61:57-65.
    • (2006) Plant Foods Hum Nutr , vol.61 , pp. 57-65
    • Lu, Y.1    Zhang, C.2    Bucheli, P.3    Wei, D.4
  • 21
  • 22
    • 62549095435 scopus 로고    scopus 로고
    • Effects of naringin on the proliferation and osteogenic differentiation of human bone mesenchymal stem cell
    • Zhang P, Dai KR, Yan SG, Yan WQ, Zhang C, Chen DQ, Xu B, Xu ZW: Effects of naringin on the proliferation and osteogenic differentiation of human bone mesenchymal stem cell. Eur J Pharmacol 2009;607:1-5.
    • (2009) Eur J Pharmacol , vol.607 , pp. 1-5
    • Zhang, P.1    Dai, K.R.2    Yan, S.G.3    Yan, W.Q.4    Zhang, C.5    Chen, D.Q.6    Xu, B.7    Xu, Z.W.8
  • 23
    • 84878542061 scopus 로고    scopus 로고
    • Naringin promotes osteoblast differentiation and effectively reverses ovariectomy-associated osteoporosis
    • Li N, Jiang Y, Wooley PH, Xu Z, Yang SY: Naringin promotes osteoblast differentiation and effectively reverses ovariectomy-associated osteoporosis. J Orthop Sci 2013;18:478-485.
    • (2013) J Orthop Sci , vol.18 , pp. 478-485
    • Li, N.1    Jiang, Y.2    Wooley, P.H.3    Xu, Z.4    Yang, S.Y.5
  • 24
    • 80052266836 scopus 로고    scopus 로고
    • Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of rankl-induced nf-kappab and erk activation
    • Ang ES, Yang X, Chen H, Liu Q, Zheng MH, Xu J: Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of rankl-induced nf-kappab and erk activation. FEBS Lett 2011;585:2755-2762.
    • (2011) FEBS Lett , vol.585 , pp. 2755-2762
    • Ang, E.S.1    Yang, X.2    Chen, H.3    Liu, Q.4    Zheng, M.H.5    Xu, J.6
  • 25
    • 84917739726 scopus 로고    scopus 로고
    • The inactivation of jak2/stat3 signaling and desensitization of m1 machr in minimal hepatic encephalopathy (mhe) and the protection of naringin against mhe
    • Ding S, Hu J, Yang J, Liu L, Huang W, Gu X, Ye Y, Huang L, Liang Y, Chen B, Zhuge Q: The inactivation of jak2/stat3 signaling and desensitization of m1 machr in minimal hepatic encephalopathy (mhe) and the protection of naringin against mhe. Cell Physiol Biochem 2014;34:1933-1950.
    • (2014) Cell Physiol Biochem , vol.34 , pp. 1933-1950
    • Ding, S.1    Hu, J.2    Yang, J.3    Liu, L.4    Huang, W.5    Gu, X.6    Ye, Y.7    Huang, L.8    Liang, Y.9    Chen, B.10    Zhuge, Q.11
  • 26
    • 77950204604 scopus 로고    scopus 로고
    • Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (umr-106) cells
    • Pang WY, Wang XL, Mok SK, Lai WP, Chow HK, Leung PC, Yao XS, Wong MS: Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (umr-106) cells. Br J Pharmacol 2010;159:1693-1703.
    • (2010) Br J Pharmacol , vol.159 , pp. 1693-1703
    • Pang, W.Y.1    Wang, X.L.2    Mok, S.K.3    Lai, W.P.4    Chow, H.K.5    Leung, P.C.6    Yao, X.S.7    Wong, M.S.8
  • 27
    • 33750872026 scopus 로고    scopus 로고
    • Effect of naringin on bone cells
    • Wong RW, Rabie AB: Effect of naringin on bone cells. J Orthop Res 2006;24:2045-2050.
    • (2006) J Orthop Res , vol.24 , pp. 2045-2050
    • Wong, R.W.1    Rabie, A.B.2
  • 28
    • 44649083061 scopus 로고    scopus 로고
    • Naringin-induced bone morphogenetic protein-2 expression via pi3k, akt, c-fos/c-jun and ap-1 pathway in osteoblasts
    • Wu JB, Fong YC, Tsai HY, Chen YF, Tsuzuki M, Tang CH: Naringin-induced bone morphogenetic protein-2 expression via pi3k, akt, c-fos/c-jun and ap-1 pathway in osteoblasts. Eur J Pharmacol 2008;588:333-341.
    • (2008) Eur J Pharmacol , vol.588 , pp. 333-341
    • Wu, J.B.1    Fong, Y.C.2    Tsai, H.Y.3    Chen, Y.F.4    Tsuzuki, M.5    Tang, C.H.6
  • 33
    • 84555189535 scopus 로고    scopus 로고
    • Bone measurements by peripheral quantitative computed tomography in rodents
    • Gasser JA, Willnecker J: Bone measurements by peripheral quantitative computed tomography in rodents. Methods Mol Biol 2012;816:477-498.
    • (2012) Methods Mol Biol , vol.816 , pp. 477-498
    • Gasser, J.A.1    Willnecker, J.2
  • 34
    • 38949148608 scopus 로고    scopus 로고
    • Improvement of bone properties and enhancement of mineralization by ethanol extract of fructus ligustri lucidi
    • Zhang Y, Leung PC, Che CT, Chow HK, Wu CF, Wong MS: Improvement of bone properties and enhancement of mineralization by ethanol extract of fructus ligustri lucidi. Br J Nutr 2008;99:494-502.
    • (2008) Br J Nutr , vol.99 , pp. 494-502
    • Zhang, Y.1    Leung, P.C.2    Che, C.T.3    Chow, H.K.4    Wu, C.F.5    Wong, M.S.6
  • 36
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical wnt pathway by promoting gsk-3-independent beta-catenin degradation
    • Topol L, Jiang X, Choi H, Garrett-Beal L, Carolan PJ, Yang Y: Wnt-5a inhibits the canonical wnt pathway by promoting gsk-3-independent beta-catenin degradation. J Cell Biol 2003;162:899-908.
    • (2003) J Cell Biol , vol.162 , pp. 899-908
    • Topol, L.1    Jiang, X.2    Choi, H.3    Garrett-Beal, L.4    Carolan, P.J.5    Yang, Y.6
  • 38
    • 0034933057 scopus 로고    scopus 로고
    • Novel mechanism of wnt signalling inhibition mediated by dickkopf-1 interaction with lrp6/arrow
    • Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA: Novel mechanism of wnt signalling inhibition mediated by dickkopf-1 interaction with lrp6/arrow. Nat Cell Biol 2001;3:683-686.
    • (2001) Nat Cell Biol , vol.3 , pp. 683-686
    • Bafico, A.1    Liu, G.2    Yaniv, A.3    Gazit, A.4    Aaronson, S.A.5
  • 40
    • 0036166297 scopus 로고    scopus 로고
    • Wnt signals are transmitted through n-terminally dephosphorylated beta-catenin
    • Staal FJ, Noort Mv M, Strous GJ, Clevers HC: Wnt signals are transmitted through n-terminally dephosphorylated beta-catenin. EMBO Rep 2002;3:63-68.
    • (2002) EMBO Rep , vol.3 , pp. 63-68
    • Staal, F.J.1    Noort Mv, M.2    Strous, G.J.3    Clevers, H.C.4
  • 42
    • 0034710915 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin
    • Playford MP, Bicknell D, Bodmer WF, Macaulay VM: Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin. Proc Natl Acad Sci U S A 2000;97:12103-12108.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12103-12108
    • Playford, M.P.1    Bicknell, D.2    Bodmer, W.F.3    Macaulay, V.M.4
  • 43
    • 0037155691 scopus 로고    scopus 로고
    • Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
    • Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, Zhang Z, Lin X, He X: Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 2002;108:837-847.
    • (2002) Cell , vol.108 , pp. 837-847
    • Liu, C.1    Li, Y.2    Semenov, M.3    Han, C.4    Baeg, G.H.5    Tan, Y.6    Zhang, Z.7    Lin, X.8    He, X.9
  • 44
    • 0035967967 scopus 로고    scopus 로고
    • Signal transduction: Signaling specificity - A complex affair
    • Weston CR, Davis RJ: Signal transduction: Signaling specificity - A complex affair. Science 2001;292:2439-2440.
    • (2001) Science , vol.292 , pp. 2439-2440
    • Weston, C.R.1    Davis, R.J.2
  • 45
    • 0035967897 scopus 로고    scopus 로고
    • Regulation of gsk-3: A cellular multiprocessor
    • Harwood AJ: Regulation of gsk-3: A cellular multiprocessor. Cell 2001;105:821-824.
    • (2001) Cell , vol.105 , pp. 821-824
    • Harwood, A.J.1
  • 46
    • 0034969088 scopus 로고    scopus 로고
    • A common phosphate binding site explains the unique substrate specificity of gsk3 and its inactivation by phosphorylation
    • Frame S, Cohen P, Biondi RM: A common phosphate binding site explains the unique substrate specificity of gsk3 and its inactivation by phosphorylation. Mol Cell 2001;7:1321-1327.
    • (2001) Mol Cell , vol.7 , pp. 1321-1327
    • Frame, S.1    Cohen, P.2    Biondi, R.M.3
  • 49
    • 77951881189 scopus 로고    scopus 로고
    • Amp-activated protein kinase (ampk) cross-talks with canonical wnt signaling via phosphorylation of -catenin at ser 552
    • Zhao J, Yue W, Zhu MJ, Sreejayan N, Du M: Amp-activated protein kinase (ampk) cross-talks with canonical wnt signaling via phosphorylation of -catenin at ser 552. Biochem Biophys Res Comm 2010;395:146-151.
    • (2010) Biochem Biophys Res Comm , vol.395 , pp. 146-151
    • Zhao, J.1    Yue, W.2    Zhu, M.J.3    Sreejayan, N.4    Du, M.5
  • 50
    • 51449094922 scopus 로고    scopus 로고
    • Effects of an amp-activated protein kinase inhibitor, compound c, on adipogenic differentiation of 3t3-l1 cells
    • Gao Y, Zhou Y, Xu A, Wu D: Effects of an amp-activated protein kinase inhibitor, compound c, on adipogenic differentiation of 3t3-l1 cells. Biol Pharm Bull 2008;31:1716-1722.
    • (2008) Biol Pharm Bull , vol.31 , pp. 1716-1722
    • Gao, Y.1    Zhou, Y.2    Xu, A.3    Wu, D.4
  • 51
    • 78149464882 scopus 로고    scopus 로고
    • Akti-1/2, an allosteric inhibitor of akt 1 and 2, efficiently inhibits camkialpha activity and aryl hydrocarbon receptor pathway
    • Gilot D, Giudicelli F, Lagadic-Gossmann D, Fardel O: Akti-1/2, an allosteric inhibitor of akt 1 and 2, efficiently inhibits camkialpha activity and aryl hydrocarbon receptor pathway. Chem Biol Interact 2010;188:546-552.
    • (2010) Chem Biol Interact , vol.188 , pp. 546-552
    • Gilot, D.1    Giudicelli, F.2    Lagadic-Gossmann, D.3    Fardel, O.4
  • 52
    • 37249079346 scopus 로고    scopus 로고
    • Small-molecule dissection of bmp signaling
    • Anderson GJ, Darshan D: Small-molecule dissection of bmp signaling. Nat Chem Biol 2008;4:15-16.
    • (2008) Nat Chem Biol , vol.4 , pp. 15-16
    • Anderson, G.J.1    Darshan, D.2
  • 53
    • 0035206443 scopus 로고    scopus 로고
    • Minireview: The opg/rankl/rank system
    • Khosla S: Minireview: The opg/rankl/rank system. Endocrinology 2001;142:5050-5055.
    • (2001) Endocrinology , vol.142 , pp. 5050-5055
    • Khosla, S.1
  • 54
    • 58249096196 scopus 로고    scopus 로고
    • Activation of amp kinase and inhibition of rho kinase induce the mineralization of osteoblastic mc3t3-e1 cells through endothelial nos and bmp-2 expression
    • Kanazawa I, Yamaguchi T, Yano S, Yamauchi M, Sugimoto T: Activation of amp kinase and inhibition of rho kinase induce the mineralization of osteoblastic mc3t3-e1 cells through endothelial nos and bmp-2 expression. Am J Physiol Endocrinol Metab 2009;296:E139-146.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. E139-146
    • Kanazawa, I.1    Yamaguchi, T.2    Yano, S.3    Yamauchi, M.4    Sugimoto, T.5
  • 56
    • 84920924822 scopus 로고    scopus 로고
    • Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the wnt/-catenin pathway
    • Rong S, Zhao X, Jin X, Zhang Z, Chen L, Zhu Y, Yuan W: Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the wnt/-catenin pathway. Cell Physiol Biochem 2014;34:2049-2060.
    • (2014) Cell Physiol Biochem , vol.34 , pp. 2049-2060
    • Rong, S.1    Zhao, X.2    Jin, X.3    Zhang, Z.4    Chen, L.5    Zhu, Y.6    Yuan, W.7


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