Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of RANKL-induced NF-κB and ERK activation

FEBS Letters

Volumn 585, Issue 17, 2011, Pages 2755-2762

  Ang, Estabelle S M ^a   Yang, Xiaohong ^b   Chen, Honghui ^b   Liu, Qian ^a   Zheng, Ming H ^a   Xu, Jiake ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b JINAN UNIVERSITY   (China)

Author keywords

Bone resorption; Naringin; NF B; Osteoclastogenesis; RANKL

Indexed keywords

AURANTIIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCLAST DIFFERENTIATION FACTOR;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC MARKER; HUMAN; HUMAN TISSUE; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BONE RESORPTION; CELL LINE; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVANONES; MICE; MICROSCOPY, CONFOCAL; NF-KAPPA B; OSTEOCLASTS; OSTEOGENESIS; RANK LIGAND; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

RATTUS;

EID: 80052266836     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.07.046     Document Type: Article

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