Vascular calcification in chronic kidney disease is induced by bone morphogenetic protein-2 via a mechanism involving the Wnt/β-catenin pathway

Cellular Physiology and Biochemistry

Volumn 34, Issue 6, 2014, Pages 2049-2060

  Rong, Shu ^a   Zhao, Xuezhi ^b   Jin, Xiucai ^c   Zhang, Zheng ^a   Chen, Lei ^a   Zhu, Yuxian ^b   Yuan, Weijie ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Bone morphogenetic protein 2; Chronic kidney disease; Vascular calcification; Wnt catenin signaling pathway

Indexed keywords

ALKALINE PHOSPHATASE; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 2; CALCIUM; OSTEOCALCIN; PHOSPHATE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR MSX2; TRANSCRIPTION FACTOR PIT 1; TRANSCRIPTION FACTOR RUNX2; BMP2 PROTEIN, HUMAN; NEUTRALIZING ANTIBODY;

ADULT; AGED; APOPTOSIS; ARTICLE; BLOOD VESSEL CALCIFICATION; BONE DEVELOPMENT; CELL DIFFERENTIATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; SMOOTH MUSCLE FIBER; UPREGULATION; WNT SIGNALING PATHWAY; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CALCINOSIS; CHRONIC KIDNEY FAILURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MIDDLE AGED; OSTEOBLAST; PATHOLOGY; RAT; VASCULAR SMOOTH MUSCLE; VERY ELDERLY;

RATTUS;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIBODIES, NEUTRALIZING; APOPTOSIS; BETA CATENIN; BONE MORPHOGENETIC PROTEIN 2; CALCINOSIS; CELL DIFFERENTIATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MALE; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; OSTEOBLASTS; RATS; RENAL INSUFFICIENCY, CHRONIC; WNT SIGNALING PATHWAY;

EID: 84920924822     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000366400     Document Type: Article

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