Single-Cell Analysis: Visualizing Pharmaceutical and Metabolite Uptake in Cells with Label-Free 3D Mass Spectrometry Imaging

Analytical Chemistry

Volumn 87, Issue 13, 2015, Pages 6696-6702

  Passarelli, Melissa K ^a   Newman, Carla F ^b   Marshall, Peter S ^b   West, Andrew ^b   Gilmore, Ian S ^a,c   Bunch, Josephine ^a,c   Alexander, Morgan R ^c   Dollery, Colin T ^b  

^a NATIONAL PHYSICAL LABORATORY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; CELL CULTURE; CYTOLOGY; DRUG DOSAGE; KETONES; MACROPHAGES; MASS SPECTROMETRY; METABOLITES; MOBILE SECURITY; SECONDARY ION MASS SPECTROMETRY; THREE DIMENSIONAL COMPUTER GRAPHICS;

CHEMICAL INFORMATION; HIGH-LATERAL RESOLUTION; MASS SPECTROMETRIC DETECTION; MASS-SPECTROMETRY IMAGING; MORPHOLOGICAL FEATURES; PHARMACEUTICAL COMPOUNDS; PHARMACEUTICAL DEVELOPMENT; SINGLECELL ANALYSIS;

CELLS;

ANIMAL; MASS SPECTROMETRY; PHARMACOKINETICS; PROCEDURES; RAT; SINGLE CELL ANALYSIS; SPRAGUE DAWLEY RAT; TRANSFORMED CELL LINE;

ANIMALS; CELL LINE, TRANSFORMED; MASS SPECTROMETRY; PHARMACOKINETICS; RATS; RATS, SPRAGUE-DAWLEY; SINGLE-CELL ANALYSIS;

EID: 84936879616     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/acs.analchem.5b00842     Document Type: Article

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