Metabolic radiolabeling: Experimental tool or Trojan horse? 35S-methionine induces DNA fragmentation and p53-dependent ROS production

FASEB Journal

Volumn 15, Issue 9, 2001, Pages 1562-1568

  Hu, Valerie W ^a   Heikka, Daniel S ^a   Dieffenbach, Paul B ^a   Ha, Linan ^a  

^a GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

DNA fragmentation; Metabolic labeling; p53; Radioisotopes; Reactive oxygen species

Indexed keywords

DNA FRAGMENT; METHIONINE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SULFUR 35;

ANIMAL CELL; APOPTOSIS; ARTICLE; BETA RADIATION; CELL CYCLE; CELL FUNCTION; CELL METABOLISM; CELL PROLIFERATION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DOSE RESPONSE; HYPOXIA; ISOTOPE LABELING; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE FIBER;

ANIMALS; CELL HYPOXIA; CELLS, CULTURED; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; METHIONINE; RABBITS; REACTIVE OXYGEN SPECIES; SULFUR RADIOISOTOPES; THYMIDINE; TIME FACTORS; TRITIUM; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034925484     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.01-0102com     Document Type: Article

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