Pathophysiologically relevant in vitro tumor models for drug screening

Drug Discovery Today

Volumn 20, Issue 7, 2015, Pages 848-855

  Das, Viswanath ^a,c   Bruzzese, Francesca ^b,c   Konečný, Petr ^a,c   Iannelli, Federica ^b,c   Budillon, Alfredo ^b,c   Hajdúch, Marián ^a,c  

^a PALACKÝ UNIVERSITY   (Czech Republic)

^b NATIONAL CANCER INSTITUTE   (Italy)

^c European Advanced Translational Research Infrastructure in Medicine European Research Infrastructure Consortium   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; DRUG SCREENING; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MICROFLUIDICS; PATHOPHYSIOLOGY; PRIMARY CELL CULTURE; PRIMARY TUMOR; TUMOR MICROENVIRONMENT; TUMOR MODEL; ANIMAL; ANIMAL TESTING ALTERNATIVE; CELL COMMUNICATION; CULTURE TECHNIQUE; DOSE RESPONSE; DRUG DEVELOPMENT; DRUG EFFECTS; HIGH THROUGHPUT SCREENING; METABOLISM; NEOPLASMS; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMAL TESTING ALTERNATIVES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL COMMUNICATION; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; DRUG SCREENING ASSAYS, ANTITUMOR; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; NEOPLASMS; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

EID: 84936846646     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2015.04.004     Document Type: Review

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