-
3
-
-
84881583186
-
Programmed cell death with a necrotic-like phenotype
-
Morgan M and Liu Z (2013) Programmed cell death with a necrotic-like phenotype. Biomol Concepts 4, 259-275
-
(2013)
Biomol Concepts
, vol.4
, pp. 259-275
-
-
Morgan, M.1
Liu, Z.2
-
4
-
-
22544432640
-
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
-
Kroemer G, El-Deiry WS, Golstein P et al (2005) Classification of cell death: recommendations of the Nomenclature Committee on Cell Death. Cell Death Differ 12 Suppl 2, 1463-1467
-
(2005)
Cell Death Differ 12 Suppl
, vol.2
, pp. 1463-1467
-
-
Kroemer, G.1
El-Deiry, W.S.2
Golstein, P.3
-
5
-
-
0033576675
-
More than one way to die: apoptosis, necrosis and reactive oxygen damage
-
Fiers W, Beyaert R, Declercq W and Vandenabeele P (1999) More than one way to die: apoptosis, necrosis and reactive oxygen damage. Oncogene 18, 7719-7730
-
(1999)
Oncogene
, vol.18
, pp. 7719-7730
-
-
Fiers, W.1
Beyaert, R.2
Declercq, W.3
Vandenabeele, P.4
-
6
-
-
84881075820
-
RIP3: a molecular switch for necrosis and inflammation
-
Moriwaki K and Chan FKM (2013) RIP3: a molecular switch for necrosis and inflammation. Genes Dev 27, 1640-1649
-
(2013)
Genes Dev
, vol.27
, pp. 1640-1649
-
-
Moriwaki, K.1
Chan, F.K.M.2
-
7
-
-
84880357849
-
Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury
-
Linkermann A, Brasen JH, Darding M et al (2013) Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury. Proc Nat Acad Sci U S A 110, 12024-12029
-
(2013)
Proc Nat Acad Sci U S A
, vol.110
, pp. 12024-12029
-
-
Linkermann, A.1
Brasen, J.H.2
Darding, M.3
-
9
-
-
84925677956
-
Activation of Necroptosis in Multiple Sclerosis
-
Ofengeim D, Ito Y, Najafov A et al (2015) Activation of Necroptosis in Multiple Sclerosis. Cell Rep 10, 1836-1849
-
(2015)
Cell Rep
, vol.10
, pp. 1836-1849
-
-
Ofengeim, D.1
Ito, Y.2
Najafov, A.3
-
10
-
-
1642299768
-
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation
-
Lin Y, Choksi S, Shen HM et al (2004) Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. J Biol Chem 279, 10822-10828
-
(2004)
J Biol Chem
, vol.279
, pp. 10822-10828
-
-
Lin, Y.1
Choksi, S.2
Shen, H.M.3
-
11
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
Holler N, Zaru R, Micheau O et al (2000) Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 1, 489-495
-
(2000)
Nat Immunol
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
-
12
-
-
77955035878
-
Reactive oxygen species in TNFalpha-induced signaling and cell death
-
Morgan MJ and Liu ZG (2010) Reactive oxygen species in TNFalpha-induced signaling and cell death. Mol Cells 30, 1-12
-
(2010)
Mol Cells
, vol.30
, pp. 1-12
-
-
Morgan, M.J.1
Liu, Z.G.2
-
13
-
-
0042090891
-
The role of the deathdomain kinase RIP in tumour-necrosis-factor-induced activation of mitogen-activated protein kinases
-
Devin A, Lin Y and Liu ZG (2003) The role of the deathdomain kinase RIP in tumour-necrosis-factor-induced activation of mitogen-activated protein kinases. EMBO Rep 4, 623-627
-
(2003)
EMBO Rep
, vol.4
, pp. 623-627
-
-
Devin, A.1
Lin, Y.2
Liu, Z.G.3
-
14
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A, Hitomi J, Germscheid M et al (2008) Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol 4, 313-321
-
(2008)
Nat Chem Biol
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
-
15
-
-
0347065342
-
A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
-
Chan FK, Shisler J, Bixby JG et al (2003) A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J Biol Chem 278, 51613-51621
-
(2003)
J Biol Chem
, vol.278
, pp. 51613-51621
-
-
Chan, F.K.1
Shisler, J.2
Bixby, J.G.3
-
16
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev A, Huang Z, Boyce M et al (2005) Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat Chem Biol 1, 112-119
-
(2005)
Nat Chem Biol
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
-
17
-
-
66449133280
-
Phosphorylationdriven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho YS, Challa S, Moquin D et al (2009) Phosphorylationdriven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137, 1112-1123
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
-
18
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S, Wang L, Miao L et al (2009) Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 137, 1100-1111
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
-
19
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang DW, Shao J, Lin J et al (2009) RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325, 332-336
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
-
20
-
-
0037088632
-
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
-
Sun X, Yin J, Starovasnik MA, Fairbrother WJ and Dixit VM (2002) Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J Biol Chem 277, 9505-9511
-
(2002)
J Biol Chem
, vol.277
, pp. 9505-9511
-
-
Sun, X.1
Yin, J.2
Starovasnik, M.A.3
Fairbrother, W.J.4
Dixit, V.M.5
-
21
-
-
84864240409
-
The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis
-
Li J, McQuade T, Siemer AB et al (2012) The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis. Cell 150, 339-350
-
(2012)
Cell
, vol.150
, pp. 339-350
-
-
Li, J.1
McQuade, T.2
Siemer, A.B.3
-
22
-
-
84901422731
-
RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis
-
Rickard JA, O'Donnell JA, Evans JM et al (2014) RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis. Cell 157, 1175-1188
-
(2014)
Cell
, vol.157
, pp. 1175-1188
-
-
Rickard, J.A.1
O'Donnell, J.A.2
Evans, J.M.3
-
23
-
-
84901386193
-
RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3
-
Dillon CP, Weinlich R, Rodriguez DA et al (2014) RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3. Cell 157, 1189-1202
-
(2014)
Cell
, vol.157
, pp. 1189-1202
-
-
Dillon, C.P.1
Weinlich, R.2
Rodriguez, D.A.3
-
24
-
-
84961291582
-
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
-
Orozco S, Yatim N, Werner MR et al (2014) RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis. Cell Death Differ 21, 1511-1521
-
(2014)
Cell Death Differ
, vol.21
, pp. 1511-1521
-
-
Orozco, S.1
Yatim, N.2
Werner, M.R.3
-
25
-
-
84907210946
-
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
-
Dannappel M, Vlantis K, Kumari S et al (2014) RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature 513, 90-94
-
(2014)
Nature
, vol.513
, pp. 90-94
-
-
Dannappel, M.1
Vlantis, K.2
Kumari, S.3
-
26
-
-
84859467770
-
Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
-
Zhao J, Jitkaew S, Cai Z et al (2012) Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci U S A 109, 5322-5327
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 5322-5327
-
-
Zhao, J.1
Jitkaew, S.2
Cai, Z.3
-
27
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
Sun L, Wang H, Wang Z et al (2012) Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 148, 213-227
-
(2012)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
-
28
-
-
84881184694
-
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
-
Wu JF, Huang Z, Ren JM et al (2013) Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis. Cell Res 23, 994-1006
-
(2013)
Cell Res
, vol.23
, pp. 994-1006
-
-
Wu, J.F.1
Huang, Z.2
Ren, J.M.3
-
29
-
-
84884308522
-
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
-
Murphy JM, Czabotar PE, Hildebrand JM et al (2013) The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism. Immunity 39, 443-453
-
(2013)
Immunity
, vol.39
, pp. 443-453
-
-
Murphy, J.M.1
Czabotar, P.E.2
Hildebrand, J.M.3
-
30
-
-
84898027331
-
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
-
Wang HY, Sun LM, Su LJ et al (2014) Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3. Mol Cell 54, 133-146
-
(2014)
Mol Cell
, vol.54
, pp. 133-146
-
-
Wang, H.Y.1
Sun, L.M.2
Su, L.J.3
-
31
-
-
84891343566
-
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
-
Cai ZY, Jitkaew S, Zhao J et al (2014) Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol 16, 55-56
-
(2014)
Nat Cell Biol
, vol.16
, pp. 55-56
-
-
Cai, Z.Y.1
Jitkaew, S.2
Zhao, J.3
-
32
-
-
84891739370
-
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
-
Chen X, Li WJ, Ren JM et al (2014) Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death. Cell Res 24, 105-121
-
(2014)
Cell Res
, vol.24
, pp. 105-121
-
-
Chen, X.1
Li, W.J.2
Ren, J.M.3
-
33
-
-
84901280344
-
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
-
Dondelinger Y, Declercq W, Montessuit S et al (2014) MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates. Cell Rep 7, 971-981
-
(2014)
Cell Rep
, vol.7
, pp. 971-981
-
-
Dondelinger, Y.1
Declercq, W.2
Montessuit, S.3
-
34
-
-
84908072785
-
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
-
Hildebrand JM, Tanzer MC, Lucet IS et al (2014) Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death. Proc Natl Acad Sci U S A 111, 15072-15077
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 15072-15077
-
-
Hildebrand, J.M.1
Tanzer, M.C.2
Lucet, I.S.3
-
35
-
-
84930519244
-
RIPK1-and RIPK3-induced cell death mode is determined by target availability
-
Cook WD, Moujalled DM, Ralph TJ et al (2014) RIPK1-and RIPK3-induced cell death mode is determined by target availability. Cell Death Differ 21, 1600-1612
-
(2014)
Cell Death Differ
, vol.21
, pp. 1600-1612
-
-
Cook, W.D.1
Moujalled, D.M.2
Ralph, T.J.3
-
36
-
-
80755132824
-
The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation
-
Bonnet MC, Preukschat D, Welz PS et al (2011) The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation. Immunity 35, 572-582
-
(2011)
Immunity
, vol.35
, pp. 572-582
-
-
Bonnet, M.C.1
Preukschat, D.2
Welz, P.S.3
-
37
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en IL, Tsau JS, Molkentin JD, Komatsu M and Hedrick SM (2011) Mechanisms of necroptosis in T cells. J Exp Med 208, 633-641
-
(2011)
J Exp Med
, vol.208
, pp. 633-641
-
-
Ch'en, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
38
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
Dillon CP, Oberst A, Weinlich R et al (2012) Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 1, 401-407
-
(2012)
Cell Rep
, vol.1
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
-
39
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser WJ, Upton JW, Long AB et al (2011) RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368-372
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
-
40
-
-
80053087284
-
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
-
Lu JV, Weist BM, van Raam BJ et al (2011) Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Natl Acad Sci U S A 108, 15312-15317
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 15312-15317
-
-
Lu, J.V.1
Weist, B.M.2
van Raam, B.J.3
-
41
-
-
84859424337
-
IAPs limit activation of RIP kinases by TNF receptor 1 during development
-
Moulin M, Anderton H, Voss AK et al (2012) IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J 31, 1679-1691
-
(2012)
EMBO J
, vol.31
, pp. 1679-1691
-
-
Moulin, M.1
Anderton, H.2
Voss, A.K.3
-
42
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A, Dillon CP, Weinlich R et al (2011) Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 471, 363-367
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
-
43
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang HB, Zhou XH, McQuade T, Li JH, Chan FKM and Zhang JK (2011) Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 471, 373-376
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.B.1
Zhou, X.H.2
McQuade, T.3
Li, J.H.4
Chan, F.K.M.5
Zhang, J.K.6
-
44
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D, Beyaert R, Denecker G et al (1998) Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J Exp Med 187, 1477-1485
-
(1998)
J Exp Med
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
-
45
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin Y, Devin A, Rodriguez Y and Liu ZG (1999) Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev 13, 2514-2526
-
(1999)
Genes Dev
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
46
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
Feng S, Yang Y, Mei Y et al (2007) Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signal 19, 2056-2067
-
(2007)
Cell Signal
, vol.19
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
-
47
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
O'Donnell MA, Perez-Jimenez E, Oberst A et al (2011) Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol 13, 1437-1442
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1437-1442
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
-
48
-
-
80053087284
-
Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity
-
Lu JV, Weist BM, van Raam BJ et al (2011) Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity. Proc Nat Acad Sci U S A 108, 15312-15317
-
(2011)
Proc Nat Acad Sci U S A
, vol.108
, pp. 15312-15317
-
-
Lu, J.V.1
Weist, B.M.2
van Raam, B.J.3
-
49
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
335-U108
-
Gunther C, Martini E, Wittkopf N et al (2011) Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 477, 335-U108
-
(2011)
Nature
, vol.477
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
-
50
-
-
80052850704
-
FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation
-
330-U102
-
Welz PS, Wullaert A, Vlantis K et al (2011) FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature 477, 330-U102
-
(2011)
Nature
, vol.477
-
-
Welz, P.S.1
Wullaert, A.2
Vlantis, K.3
-
51
-
-
0027858222
-
Cell membrane permeabilization and cellular collapse, followed by loss of dehydrogenase activity: early events in tumour necrosis factor-induced cytotoxicity
-
Grooten J, Goossens V, Vanhaesebroeck B and Fiers W (1993) Cell membrane permeabilization and cellular collapse, followed by loss of dehydrogenase activity: early events in tumour necrosis factor-induced cytotoxicity. Cytokine 5, 546-555
-
(1993)
Cytokine
, vol.5
, pp. 546-555
-
-
Grooten, J.1
Goossens, V.2
Vanhaesebroeck, B.3
Fiers, W.4
-
52
-
-
0023697978
-
Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
-
Laster SM, Wood JG and Gooding LR (1988) Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J Immunol 141, 2629-2634
-
(1988)
J Immunol
, vol.141
, pp. 2629-2634
-
-
Laster, S.M.1
Wood, J.G.2
Gooding, L.R.3
-
53
-
-
0034910509
-
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria
-
Denecker G, Vercammen D, Steemans M et al (2001) Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria. Cell Death Differ 8, 829-840
-
(2001)
Cell Death Differ
, vol.8
, pp. 829-840
-
-
Denecker, G.1
Vercammen, D.2
Steemans, M.3
-
54
-
-
0042525938
-
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
Sakon S, Xue X, Takekawa M et al (2003) NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J 22, 3898-3909
-
(2003)
EMBO J
, vol.22
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
-
55
-
-
0033587070
-
Identification of RIP3, a RIP-like kinase that activates apoptosis and NF kappa B
-
Yu PW, Huang BCB, Shen M et al (1999) Identification of RIP3, a RIP-like kinase that activates apoptosis and NF kappa B. Curr Biol 9, 539-542
-
(1999)
Curr Biol
, vol.9
, pp. 539-542
-
-
Yu, P.W.1
Huang, B.C.B.2
Shen, M.3
-
56
-
-
0033546276
-
RIP3, a novel apoptosis-inducing kinase
-
Sun XQ, Lee J, Navas T, Baldwin DT, Stewart TA and Dixit VM (1999) RIP3, a novel apoptosis-inducing kinase. J Biol Chem 274, 16871-16875
-
(1999)
J Biol Chem
, vol.274
, pp. 16871-16875
-
-
Sun, X.Q.1
Lee, J.2
Navas, T.3
Baldwin, D.T.4
Stewart, T.A.5
Dixit, V.M.6
-
57
-
-
0034685982
-
The RIP-like kinase, RIP3, induces apoptosis and NF-kappa B nuclear translocation and localizes to mitochondria
-
Kasof GM, Prosser JC, Liu DR, Lorenzi MV and Gomes BC (2000) The RIP-like kinase, RIP3, induces apoptosis and NF-kappa B nuclear translocation and localizes to mitochondria. FEBS Lett 473, 285-291
-
(2000)
FEBS Lett
, vol.473
, pp. 285-291
-
-
Kasof, G.M.1
Prosser, J.C.2
Liu, D.R.3
Lorenzi, M.V.4
Gomes, B.C.5
-
58
-
-
84930374188
-
Methylation-Dependent Loss of RIP3 Expression in Cancer Represses Programmed Necrosis in Response to Chemotherapeutics
-
Koo G-B, Morgan MJ, Lee D-G et al (2015) Methylation-Dependent Loss of RIP3 Expression in Cancer Represses Programmed Necrosis in Response to Chemotherapeutics. Cell Res 25, 707-725
-
(2015)
Cell Res
, vol.25
, pp. 707-725
-
-
Koo, G.-B.1
Morgan, M.J.2
Lee, D.-G.3
-
59
-
-
19344374275
-
RIP3 beta and RIP3 gamma, two novel splice variants of receptor-interacting protein 3 (RIP3), downregulate RIP3-induced apoptosis
-
Yang Y, Hu W, Feng S, Ma J and Wu M (2005) RIP3 beta and RIP3 gamma, two novel splice variants of receptor-interacting protein 3 (RIP3), downregulate RIP3-induced apoptosis. Biochem Biophys Res Commun 332, 181-187
-
(2005)
Biochem Biophys Res Commun
, vol.332
, pp. 181-187
-
-
Yang, Y.1
Hu, W.2
Feng, S.3
Ma, J.4
Wu, M.5
-
60
-
-
0842304221
-
Kinase RIP3 is dispensable for normal NF-KBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and toll-like receptors 2 and 4
-
Newton K, Sun XQ and Dixit VM (2004) Kinase RIP3 is dispensable for normal NF-KBs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and toll-like receptors 2 and 4. Mol Cell Biol 24, 1464-1469
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1464-1469
-
-
Newton, K.1
Sun, X.Q.2
Dixit, V.M.3
-
61
-
-
79952284127
-
Hallmarks of Cancer: The Next Generation
-
Hanahan D and Weinberg RA (2011) Hallmarks of Cancer: The Next Generation. Cell 144, 646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
62
-
-
84906877361
-
RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage
-
Nugues AL, El Bouazzati H, Hetuin D et al (2014) RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavage. Cell Death Dis 5, e1384
-
(2014)
Cell Death Dis
, vol.5
-
-
Nugues, A.L.1
El Bouazzati, H.2
Hetuin, D.3
-
63
-
-
84936133277
-
RIP1 Kinase Is an Oncogenic Driver in Melanoma
-
Liu XY, Lai F, Yan XG et al (2015) RIP1 Kinase Is an Oncogenic Driver in Melanoma. Cancer Res 75, 1736-1748
-
(2015)
Cancer Res
, vol.75
, pp. 1736-1748
-
-
Liu, X.Y.1
Lai, F.2
Yan, X.G.3
-
64
-
-
33646456046
-
Microarray analysis of promoter methylation in lung cancers
-
Fukasawa M, Kimura M, Morita S et al (2006) Microarray analysis of promoter methylation in lung cancers. J Hum Genet 51, 368-374
-
(2006)
J Hum Genet
, vol.51
, pp. 368-374
-
-
Fukasawa, M.1
Kimura, M.2
Morita, S.3
-
65
-
-
2642536197
-
Alkylating DNA damage stimulates a regulated form of necrotic cell death
-
Zong WX, Ditsworth D, Bauer DE, Wang ZQ and Thompson CB (2004) Alkylating DNA damage stimulates a regulated form of necrotic cell death. Genes Dev 18, 1272-1282
-
(2004)
Genes Dev
, vol.18
, pp. 1272-1282
-
-
Zong, W.X.1
Ditsworth, D.2
Bauer, D.E.3
Wang, Z.Q.4
Thompson, C.B.5
-
66
-
-
63849115360
-
Parthanatos, a messenger of death
-
David KK, Andrabi SA, Dawson TM and Dawson VL (2009) Parthanatos, a messenger of death. Front Biosci 14, 1116-1128
-
(2009)
Front Biosci
, vol.14
, pp. 1116-1128
-
-
David, K.K.1
Andrabi, S.A.2
Dawson, T.M.3
Dawson, V.L.4
-
67
-
-
84892809449
-
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death
-
Sosna J, Voigt S, Mathieu S et al (2014) TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. Cell Mol Life Sci 71, 331-348
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 331-348
-
-
Sosna, J.1
Voigt, S.2
Mathieu, S.3
-
68
-
-
79960921946
-
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
-
Tenev T, Bianchi K, Darding M et al (2011) The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs. Mol Cell 43, 432-448
-
(2011)
Mol Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
-
69
-
-
79960922705
-
cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
-
Feoktistova M, Geserick P, Kellert B et al (2011) cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms. Mol Cell 43, 449-463
-
(2011)
Mol Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
-
70
-
-
79953282304
-
NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling
-
Biton S and Ashkenazi A (2011) NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling. Cell 145, 92-103
-
(2011)
Cell
, vol.145
, pp. 92-103
-
-
Biton, S.1
Ashkenazi, A.2
-
71
-
-
84903791583
-
The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury
-
Li JX, Feng JM, Wang Y et al (2014) The B-Raf(V600E) inhibitor dabrafenib selectively inhibits RIP3 and alleviates acetaminophen-induced liver injury. Cell Death Dis 5, e1278
-
(2014)
Cell Death Dis
, vol.5
-
-
Li, J.X.1
Feng, J.M.2
Wang, Y.3
-
72
-
-
84937635416
-
Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis
-
[Epub ahead of print]
-
Kim SK, Kim WJ, Yoon JH et al (2015) Upregulated RIP3 Expression Potentiates MLKL Phosphorylation-Mediated Programmed Necrosis in Toxic Epidermal Necrolysis. J Invest Dermatol [Epub ahead of print]
-
(2015)
J Invest Dermatol
-
-
Kim, S.K.1
Kim, W.J.2
Yoon, J.H.3
-
73
-
-
80053216174
-
Caspase-1 Protein Induces Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain (ASC)mediated Necrosis Independently of Its Catalytic Activity
-
Motani K, Kushiyama H, Imamura R, Kinoshita T, Nishiuchi T and Suda T (2011) Caspase-1 Protein Induces Apoptosis-associated Speck-like Protein Containing a Caspase Recruitment Domain (ASC)mediated Necrosis Independently of Its Catalytic Activity. J Biol Chem 286, 33963-33972
-
(2011)
J Biol Chem
, vol.286
, pp. 33963-33972
-
-
Motani, K.1
Kushiyama, H.2
Imamura, R.3
Kinoshita, T.4
Nishiuchi, T.5
Suda, T.6
|