αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression

Biochemical Journal

Volumn 466, Issue 3, 2015, Pages 525-536

  Dutta, Anindita ^a,b,e   Li, Jing ^a   Fedele, Carmine ^a,b   Sayeed, Aejaz ^a,b   Singh, Amrita ^a,b   Violette, Shelia M ^c   Manes, Thomas D ^d   Languino, Lucia R ^a,b  

^a Prostate Cancer Discovery and Development Program   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c BIOGEN   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Tata Medical Centre   (India)

Author keywords

Integrins; Matrix metalloproteinase 2 (mmp2); Prostate cancer (prca); SMAD3; Transforming growth factor (tgf) 1 receptor

Indexed keywords

ALPHAVBETA5 INTEGRIN; ALPHAVBETA6 INTEGRIN; GELATINASE A; LATENCY ASSOCIATED PEPTIDE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; VITRONECTIN RECEPTOR; INTEGRIN; MMP2 PROTEIN, HUMAN; TGFB1 PROTEIN, HUMAN; TUMOR ANTIGEN;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; UPREGULATION; BIOSYNTHESIS; CELL MOTION; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ANTIGENS, NEOPLASM; CELL LINE, TUMOR; CELL MOVEMENT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTEGRINS; MALE; MATRIX METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84935036672     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20140698     Document Type: Article

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