Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12

Journal of Biological Chemistry

Volumn 273, Issue 4, 1998, Pages 1872-1879

  Nishimura, Riko ^a,b   Kato, Yoichi ^a   Chen, Di ^a   Harris, Stephen E ^a   Mundy, Gregory R ^a   Yoneda, Toshiyuki ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; OSTEOCALCIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MESENCHYME; MOLECULAR CLONING; OSTEOBLAST; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELL;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE I; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL LINE; DNA-BINDING PROTEINS; GENES, TUMOR SUPPRESSOR; HUMANS; MICE; MOLECULAR SEQUENCE DATA; OSTEOBLASTS; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CELL SURFACE; RECEPTORS, GROWTH FACTOR; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; SMAD5 PROTEIN; TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031939744     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.4.1872     Document Type: Article

References (32)

1. Kingsley, D. M. (1994) Trends Genet. 10, 16-21
2. Hogan, B. L. M. (1996) Genes Dev. 10, 1580-1594
3. Reddi, A. H. (1994) Curr. Opin. Genet. Dev. 4, 737-744
4. Yamaguchi, A., Katagiri, T., Ikeda, T., Wozney, J. M., Rosen, V., Wang, E. A., Kahn, A. J., Suda, T., and Yoshiki, S. (1991) J. Cell Biol. 113, 681-687
5. Harris, S., Sabatini, M., Harris, M. A., Feng, J. Q., Wozney, J., and Mundy, G. R. (1994) J. Bone. Miner. Res. 9, 389-400
6. Massagué, J., Attisano, L., and Wrana, J. L. (1994) Trends Cell Biol. 4, 172-178
7. Massagué, J. (1996) Cell 85, 947-950
8. Derynck, R., and Zhang, Y. (1996) Curr. Biol. 6, 1226-1229
9. Graff, J. M., Bansal, A., and Melton, D. A. (1996) Cell 85, 479-487
10. Hoodless, P. A., Haerry, T., Abdollah, S., Stapleton, M., O'Connor M. B., Attisano, L., and Wrana, J. L. (1996) Cell 85, 489-500
11. Liu, F., Hata, A., Baker, J. C., Doody, J., Carcamo, J., Harland, R. M., and Massagué, J. (1996) Nature 381, 620-623
12. Lechleider, R. J., de Caestecker, M. P., Dehejia, A., Polymeropoulos, M. H., and Robert, A. (1996) J. Biol. Chem. 271, 17617-17620
13. Eppert, K., Scherer, S. W., Ozcelik, H., Pirone, R., Hoodless, P., Kim H., Tsui, L., Bapat, B., Gallinger, S., Andrulis, I. L., Thomsen, G. H., Attisano, L., and Wrana, J. L. (1996) Cell 86, 543-552
14. Macias-Silva, M., Abdollah, S., Hoodless, P., Pirone, R., Attisano, L., and Wrana, J. L. (1996) Cell 87, 1215-1224
15. Zhang, Y., Feng, X., Wu, R., and Derynck, R. (1996) Nature 383, 168-171
16. Chen, Y., Lebrun, J., and Vale, W. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 12992-12997
17. Hahn, S. A., Schutte, M., Hoque, A. T. M. S., Moskaluk, C. A., da Costa, L. T., Rozenblum, E., Weinstein, C. L., Fisher, A., Yeo, C. J., Hruban, R. H., and Kern, S. (1996) Science 271, 350-353
18. Lagma, G., Hata, A., Hemmati-Brivanlou, A., and Massague, J. (1996) Nature 383, 832-836
19. Wu, R., Zhang, Y., Feng, X., and Derynck, R. (1996) Mol. Cell. Biol. 17, 2521-2528
20. Topper, J. N., Cai, J., Qiu, Y., Anderson, K. R., Xu, Y.-Y., Deeds, J. D., Feeley, R., Gimeno, C. J., Woolf, E. A., Tayber, O., Mays, G. G., Sampson, B. A., Schoen, F. J., Gimbrone, M. A., and Falb, D. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 9314-9319
21. Hayashi, H., Abdollah, S., Qiu, Y., Cai, J., Xu, Y.-Y., Grinnell, B., Richardson, M. A., Topper, J. N., Gimbrone, M. A., Wrana, J. L., and Falb, D. (1997) Cell 89, 1165-1173
22. Raftery, L. A., Twombly, V., Wharton, K., and Gelbart, W. M. (1995) Genetics 139, 241-254
23. Sekelsky, J. J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H., and Gelbart, W. M. (1995) Genetics 139, 1347-1358
24. Savage, C., Das, P., Finelli, A., Townsend, S., Sun, C., Baird, S., and Padgett, R. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 790-794
25. Nishimura, R., Li, W., Kashishian, A., Mondino, A., Zhou, M., Cooper, J., and Schlessinger, J. (1993) Mol. Cell. Biol. 13, 6889-6896
26. Kretzschmar, M., Liu, F., Hata, A., Doody, J., and Massagué, J. (1997) Genes Dev. 11, 984-995
27. Katagiri, T., Yamaguchi, A., Komaki, M., Abe, E., Takahashi, N., Ikeda, T., Rosen, V., Wozney, J. M., Fujisawa, A., and Suda, T. (1994) J. Cell Biol. 127, 1755-1766
28. Yingling, J. M., Das, P., Savage, C., Zhang, M., Padgett, R. W., and Wang, X. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8940-8944
29. Riggin, G. J., Thiagalingam, S., Rosenblum, E., Weinstein, C. L., Kern, S. E., Hamilton, S. R., Willson, J. K. V., Markowitz, S. D., Kinzler, K. W., and Vogelstein, B. (1996) Nat. Genet. 13, 347-349
30. Derynck, R., Gelbart, W. M., Harland, R. M., Heldin, C.-H., Kern, S. E., Massagué, J., Melton, D. A., Mlodzik, M., Padgett, R. W., Roberts, A. B., Smith, J., Thomsen, G. H., Vogelstein, B., and Wang, X.-F. (1996) Cell 87, 173
31. Chen, X., Rubock, M. J., and Whitman, M. (1996) Nature 383, 691-696
32. Wozney, J. M., Rosen, V., Celeste, A. J., Mitsock, L. M., Whitters, M. J., Kriz, R. W., Hewick, R. M., and Wang, E. A. (1988) Science 242, 1528-1534