-
1
-
-
14944385553
-
Global cancer statistics 2002
-
Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
2
-
-
24944542337
-
Major causes of death among men and women in China
-
He J, Gu D, Wu X, Reynolds K, Duan X, Yao C, Wang J, ChenCS, Chen J, Wildman RP, Klag MJ and Whelton PK: Major causes of death among men and women in China. N Engl J Med 353: 1124-1134, 2005.
-
(2005)
N Engl J Med.
, vol.353
, pp. 1124-1134
-
-
He, J.1
Gu, D.2
Wu, X.3
Reynolds, K.4
Duan, X.5
Yao, C.6
Wang, J.7
Chen, C.S.8
Chen, J.9
Wildman, R.P.10
Klag, M.J.11
Whelton, P.K.12
-
3
-
-
31844436517
-
Early and late recurrence after liver resection for hepatocellular carcinoma: Prognostic and therapeutic implications
-
Portolani N, Coniglio A, Ghidoni S, Giovanelli M, Benetti A, Tiberio GA and Giulini SM: Early and late recurrence after liver resection for hepatocellular carcinoma: prognostic and therapeutic implications. Ann Surg 243: 229-235, 2006.
-
(2006)
Ann Surg.
, vol.243
, pp. 229-235
-
-
Portolani, N.1
Coniglio, A.2
Ghidoni, S.3
Giovanelli, M.4
Benetti, A.5
Tiberio, G.A.6
Giulini, S.M.7
-
4
-
-
45349095764
-
Survivin, the promising target in hepatocellular carcinoma gene therapy
-
Liu J, Du W and Fan D: Survivin, the promising target in hepatocellular carcinoma gene therapy. Cancer Biol Ther 7: 555-556, 2008.
-
(2008)
Cancer Biol Ther.
, vol.7
, pp. 555-556
-
-
Liu, J.1
Du, W.2
Fan, D.3
-
5
-
-
33745515023
-
Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer
-
Bierie B and Moses HL: Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer 6: 506-520, 2006.
-
(2006)
Nat Rev Cancer.
, vol.6
, pp. 506-520
-
-
Bierie, B.1
Moses, H.L.2
-
6
-
-
33845334175
-
Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer
-
Pardali K and Moustakas A: Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer. Biochim Biophys Acta 1775: 21-62, 2007.
-
(2007)
Biochim Biophys Acta.
, vol.1775
, pp. 21-62
-
-
Pardali, K.1
Moustakas, A.2
-
7
-
-
47549090432
-
TGFbeta in cancer
-
Massague J: TGFbeta in Cancer. Cell 134: 215-230, 2008.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
8
-
-
0032547895
-
TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis
-
Oft M, Heider KH and Beug H: TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol 8: 1243-1252, 1998.
-
(1998)
Curr Biol.
, vol.8
, pp. 1243-1252
-
-
Oft, M.1
Heider, K.H.2
Beug, H.3
-
10
-
-
58149236744
-
Roles of TGFbeta in metastasis
-
Padua D and Massague J: Roles of TGFbeta in metastasis. Cell Res 19: 89-102, 2009.
-
(2009)
Cell Res.
, vol.19
, pp. 89-102
-
-
Padua, D.1
Massague, J.2
-
11
-
-
0032442852
-
Smads: Transcriptional activators of TGF-beta responses
-
Derynck R, Zhang Y and Feng XH: Smads: transcriptional activators of TGF-beta responses. Cell 95: 737-740, 1998.
-
(1998)
Cell
, vol.95
, pp. 737-740
-
-
Derynck, R.1
Zhang, Y.2
Feng, X.H.3
-
12
-
-
68249090042
-
Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
-
Yamaguchi H, Shimizu M, Ban S, et al: Intraductal tubulopapillary neoplasms of the pancreas distinct from pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol 33: 1164-1172, 2009.
-
(2009)
Am J Surg Pathol
, vol.33
, pp. 1164-1172
-
-
Yamaguchi, H.1
Shimizu, M.2
Ban, S.3
-
13
-
-
67349145240
-
Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells
-
Deng H, Ravikumar TS and Yang WL: Overexpression of bone morphogenetic protein 4 enhances the invasiveness of Smad4-deficient human colorectal cancer cells. Cancer Lett 281: 220-231, 2009.
-
(2009)
Cancer Lett
, vol.281
, pp. 220-231
-
-
Deng, H.1
Ravikumar, T.S.2
Yang, W.L.3
-
15
-
-
33644884968
-
Role of transforming growth factor-beta1-smad signal transduction pathway in patients with hepatocellular carcinoma
-
Ji G, Wang X, Miao L, Liu Z, Zhang P, Zhang F and Yang J: Role of transforming growth factor-beta1-smad signal transduction pathway in patients with hepatocellular carcinoma. World J Gastroenterol 12: 644-648, 2006.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 644-648
-
-
Ji, G.1
Wang, X.2
Miao, L.3
Liu, Z.4
Zhang, P.5
Zhang, F.6
Yang, J.7
-
16
-
-
58149346113
-
Lentiviral-mediated Smad4 RNA i induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells
-
Huang S, Zhang F, Miao L, Zhang H, Fan Z, Wang X and Ji G: Lentiviral-mediated Smad4 RNA i induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells. Oncol Rep 20: 1053-1059, 2008.
-
(2008)
Oncol Rep.
, vol.20
, pp. 1053-1059
-
-
Huang, S.1
Zhang, F.2
Miao, L.3
Zhang, H.4
Fan, Z.5
Wang, X.6
Ji, G.7
-
17
-
-
19944434193
-
Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta
-
Jazag A, Ijichi H, Kanai F, et al: Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta. Oncogene 24: 662-671, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 662-671
-
-
Jazag, A.1
Ijichi, H.2
Kanai, F.3
-
18
-
-
63049091114
-
Construction and identification of lentiviral vector of RNA interference of Smad4 gene
-
Ji G, Zhang F, Zhai H, Fan Z, Fan D and Wang X: Construction and identification of lentiviral vector of RNA interference of Smad4 gene. J Fourth Mil Med Univ 27: 600-602, 2006.
-
(2006)
J Fourth Mil Med Univ.
, vol.27
, pp. 600-602
-
-
Ji, G.1
Zhang, F.2
Zhai, H.3
Fan, Z.4
Fan, D.5
Wang, X.6
-
19
-
-
58149279461
-
Identification of TRAK1 (Trafficking protein, kinesin-binding 1) as MGb2-Ag: A novel cancer biomarker
-
Zhang F, Ren G, Lu Y, et al: Identification of TRAK1 (Trafficking protein, kinesin-binding 1) as MGb2-Ag: a novel cancer biomarker. Cancer Lett 274: 250-258, 2009.
-
(2009)
Cancer Lett
, vol.274
, pp. 250-258
-
-
Zhang, F.1
Ren, G.2
Lu, Y.3
-
20
-
-
33745856213
-
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice
-
Xu X, Kobayashi S, Qiao W, et al: Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice. J Clin Invest 116: 1843-1852, 2006.
-
(2006)
J Clin Invest
, vol.116
, pp. 1843-1852
-
-
Xu, X.1
Kobayashi, S.2
Qiao, W.3
-
21
-
-
51649101150
-
Transforming growth factor-beta-mediated tumor necrosis factor-related apoptosis-inducing ligand expression and apoptosis in hepatoma cells requires functional cooperation between Smad proteins and activator protein-1
-
Herzer K, Grosse-Wilde A, Krammer PH, Galle PR and Kanzler S: Transforming growth factor-beta-mediated tumor necrosis factor-related apoptosis-inducing ligand expression and apoptosis in hepatoma cells requires functional cooperation between Smad proteins and activator protein-1. Mol Cancer Res 6: 1169-1177, 2008.
-
(2008)
Mol Cancer Res.
, vol.6
, pp. 1169-1177
-
-
Herzer, K.1
Grosse-Wilde, A.2
Krammer, P.H.3
Galle, P.R.4
Kanzler, S.5
-
23
-
-
59449090107
-
TGF-beta-induced epithelial to mesenchymal transition
-
Xu J, Lamouille S and Derynck R: TGF-beta-induced epithelial to mesenchymal transition. Cell Res 19: 156-172, 2009.
-
(2009)
Cell Res.
, vol.19
, pp. 156-172
-
-
Xu, J.1
Lamouille, S.2
Derynck, R.3
-
24
-
-
42549163274
-
Biological activity and clinical implications of the matrix metalloproteinases
-
Rydlova M, Holubec L Jr, Ludvikova M Jr, Kalfert D, Franekova J, Povysil C and Ludvikova M: Biological activity and clinical implications of the matrix metalloproteinases. Anticancer Res 28: 1389-1397, 2008.
-
(2008)
Anticancer Res.
, vol.28
, pp. 1389-1397
-
-
Rydlova, M.1
Holubec Jr., L.2
Ludvikova Jr., M.3
Kalfert, D.4
Franekova, J.5
Povysil, C.6
Ludvikova, M.7
-
25
-
-
47549116029
-
Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer
-
Oshima T, Kunisaki C, Yoshihara K, et al: Clinicopathological significance of the gene expression of matrix metalloproteinases and reversion-inducing cysteine-rich protein with Kazal motifs in patients with colorectal cancer: MMP-2 gene expression is a useful predictor of liver metastasis from colorectal cancer. Oncol Rep 19: 1285-1291, 2008.
-
(2008)
Oncol Rep.
, vol.19
, pp. 1285-1291
-
-
Oshima, T.1
Kunisaki, C.2
Yoshihara, K.3
-
26
-
-
33751523611
-
Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity
-
Taras D, Blanc JF, Rullier A, Dugot-Senant N, Laurendeau I, Vidaud M and Rosenbaum J: Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity. J Hepatol 46: 69-76, 2007.
-
(2007)
J Hepatol
, vol.46
, pp. 69-76
-
-
Taras, D.1
Blanc, J.F.2
Rullier, A.3
Dugot-Senant, N.4
Laurendeau, I.5
Vidaud, M.6
Rosenbaum, J.7
-
27
-
-
0037331713
-
Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells
-
Hirakawa S, Hong YK, Harvey N, Schacht V, Matsuda K, Libermann T and Detmar M: Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol 162: 575-586, 2003.
-
(2003)
Am J Pathol.
, vol.162
, pp. 575-586
-
-
Hirakawa, S.1
Hong, Y.K.2
Harvey, N.3
Schacht, V.4
Matsuda, K.5
Libermann, T.6
Detmar, M.7
-
28
-
-
51049113192
-
Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors
-
Qu Z, van Ginkel S, Roy AM, Westbrook L, Nasrin M, Maxuitenko Y, Frost AR , Carey D, Wang W, Li R, Grizzle WE, Thottassery JV and Kern FG: Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors. Cancer Res 68: 6232-6240, 2008.
-
(2008)
Cancer Res.
, vol.68
, pp. 6232-6240
-
-
Qu, Z.1
Van Ginkel, S.2
Roy, A.M.3
Westbrook, L.4
Nasrin, M.5
Maxuitenko, Y.6
Frost, A.R.7
Carey, D.8
Wang, W.9
Li, R.10
Grizzle, W.E.11
Thottassery, J.V.12
Kern, F.G.13
-
29
-
-
40249103622
-
Hypoxia-induced epithelial VEGF-C/VEGFR-3 up-regulation in carcinoma cell lines
-
Simiantonaki N, Jayasinghe C, Michel-Schmidt R, Peters K, Hermanns MI and Kirkpatrick CJ: Hypoxia-induced epithelial VEGF-C/VEGFR-3 up-regulation in carcinoma cell lines. Int J Oncol 32: 585-592, 2008.
-
(2008)
Int J Oncol.
, vol.32
, pp. 585-592
-
-
Simiantonaki, N.1
Jayasinghe, C.2
Michel-Schmidt, R.3
Peters, K.4
Hermanns, M.I.5
Kirkpatrick, C.J.6
-
30
-
-
66149158167
-
Post-transcriptional and post-translational regulation of PTEN by transforming growth factor-beta1
-
Yang Y, Zhou F, Fang Z, Wang L, Li Z, Sun L, Wang C, Yao W, Cai X, Jin J and Zha X: Post-transcriptional and post-translational regulation of PTEN by transforming growth factor-beta1. J Cell Biochem 106: 1102-1112, 2009.
-
(2009)
J Cell Biochem.
, vol.106
, pp. 1102-1112
-
-
Yang, Y.1
Zhou, F.2
Fang, Z.3
Wang, L.4
Li, Z.5
Sun, L.6
Wang, C.7
Yao, W.8
Cai, X.9
Jin, J.10
Zha, X.11
-
31
-
-
54049113056
-
Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2)
-
Deng J, Qian Y, Geng L, Chen J, Wang X, Xie H, Yan S, Jiang G, Zhou L and Zheng S: Involvement of p38 mitogen-activated protein kinase pathway in honokiol-induced apoptosis in a human hepatoma cell line (hepG2). Liver Int 28: 1458-1464, 2008.
-
(2008)
Liver Int.
, vol.28
, pp. 1458-1464
-
-
Deng, J.1
Qian, Y.2
Geng, L.3
Chen, J.4
Wang, X.5
Xie, H.6
Yan, S.7
Jiang, G.8
Zhou, L.9
Zheng, S.10
-
32
-
-
0030715557
-
Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma
-
McKillop IH, Schmidt CM, Cahill PA and Sitzmann JV: Altered expression of mitogen-activated protein kinases in a rat model of experimental hepatocellular carcinoma. Hepatology 26: 1484-1491, 1997.
-
(1997)
Hepatology
, vol.26
, pp. 1484-1491
-
-
McKillop, I.H.1
Schmidt, C.M.2
Cahill, P.A.3
Sitzmann, J.V.4
-
33
-
-
33646398593
-
The effects of a novel MEK inhibitor PD184161 on MEK-ER K signaling and growth in human liver cancer
-
Klein PJ, Schmidt CM, Wiesenauer CA , Choi JN, Gage EA , Yip-Schneider MT, Wiebke EA , Wang Y, Omer C and Sebolt-Leopold JS: The effects of a novel MEK inhibitor PD184161 on MEK-ER K signaling and growth in human liver cancer. Neoplasia 8: 1-8, 2006.
-
(2006)
Neoplasia
, vol.8
, pp. 1-8
-
-
Klein, P.J.1
Schmidt, C.M.2
Wiesenauer, C.A.3
Choi, J.N.4
Gage, E.A.5
Yip-Schneider, M.T.6
Wiebke, E.A.7
Wang, Y.8
Omer, C.9
Sebolt-Leopold, J.S.10
-
34
-
-
33846781365
-
Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma
-
Huynh H, Soo KC, Chow PK and Tran E: Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma. Mol Cancer Ther 6: 138-146, 2007.
-
(2007)
Mol Cancer Ther.
, vol.6
, pp. 138-146
-
-
Huynh, H.1
Soo, K.C.2
Chow, P.K.3
Tran, E.4
|