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Volumn 10, Issue 7, 2009, Pages 645-652

Defining the role of integrin αvβ6 in cancer

Author keywords

Cancer; EMT; Integrin v 6; MMPs; TGF 1

Indexed keywords

ALPHAVBETA6 INTEGRIN; FIBRONECTIN; GELATINASE B; LATENCY ASSOCIATED PEPTIDE; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; SCLEROPROTEIN; STROMELYSIN; TENASCIN; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; UROKINASE RECEPTOR; INTEGRIN; TUMOR ANTIGEN;

EID: 70249086983     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945009788680374     Document Type: Review
Times cited : (182)

References (52)
  • 1
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002; 110: 673-687
    • (2002) Cell , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 2
    • 0033551899 scopus 로고    scopus 로고
    • Integrin signaling
    • New York, NY
    • Giancotti FG, Ruoslahti E. Integrin signaling. Science (New York, NY 1999; 285: 1028-1032
    • (1999) Science , vol.285 , pp. 1028-1032
    • Giancotti, F.G.1    Ruoslahti, E.2
  • 4
    • 5044238876 scopus 로고    scopus 로고
    • Integrin signalling during tumour progression
    • Guo W, Giancotti FG. Integrin signalling during tumour progression. Nat Rev 2004; 5: 816-826
    • (2004) Nat Rev , vol.5 , pp. 816-826
    • Guo, W.1    Giancotti, F.G.2
  • 5
    • 0028978232 scopus 로고
    • Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling
    • Breuss JM, Gallo J, DeLisser HM, Klimanskaya IV, Folkesson HG, Pittet JF, et al. Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling. J Cell Sci 1995; 108 ( Pt 6): 2241-2251
    • (1995) J Cell Sci , vol.108 , Issue.PART 6 , pp. 2241-2251
    • Breuss, J.M.1    Gallo, J.2    DeLisser, H.M.3    Klimanskaya, I.V.4    Folkesson, H.G.5    Pittet, J.F.6
  • 7
    • 15844376477 scopus 로고    scopus 로고
    • Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lungs and skin
    • DOI 10.1083/jcb.133.4.921
    • Huang XZ, Wu JF, Cass D, Erle DJ, Corry D, Young SG, et al. Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin. J Cell Biol 1996; 133: 921-928 (Pubitemid 26160991)
    • (1996) Journal of Cell Biology , vol.133 , Issue.4 , pp. 921-928
    • Huang, X.-Z.1    Wu, J.F.2    Cass, D.3    Erie, D.J.4    Corry, D.5    Young, S.G.6    Farese Jr., R.V.7    Sheppard, D.8
  • 8
    • 0029944242 scopus 로고    scopus 로고
    • Re-epithelialization of normal human excisional wounds is associated with a switch from alpha v beta 5 to alpha v beta 6 integrins
    • Clark RA, Ashcroft GS, Spencer MJ, Larjava H, Ferguson MW. Re-epithelialization of normal human excisional wounds is associated with a switch from alpha v beta 5 to alpha v beta 6 integrins. British J Dermatol 1996; 135: 46-51. (Pubitemid 26225114)
    • (1996) British Journal of Dermatology , vol.135 , Issue.1 , pp. 46-51
    • Clark, R.A.F.1    Ashcroft, G.S.2    Spencer, M.-J.3    Larjava, H.4    Ferguson, M.W.J.5
  • 10
    • 0031696891 scopus 로고    scopus 로고
    • The integrin alphavbeta6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin
    • Huang X, Wu J, Spong S, Sheppard D. The integrin alphavbeta6 is critical for keratinocyte migration on both its known ligand, fibronectin, and on vitronectin. J Cell Sci 1998; 111 (Pt 15): 2189-2195
    • (1998) J Cell Sci , vol.111 , Issue.PART 15 , pp. 2189-2195
    • Huang, X.1    Wu, J.2    Spong, S.3    Sheppard, D.4
  • 11
    • 33645299331 scopus 로고    scopus 로고
    • Alphavbeta6 integrin in wound healing and cancer of the oral cavity
    • Thomas GJ, Nystrom ML, Marshall JF. Alphavbeta6 integrin in wound healing and cancer of the oral cavity. J Oral Pathol Med 2006; 35: 1-10.
    • (2006) J Oral Pathol Med , vol.35 , pp. 1-10
    • Thomas, G.J.1    Nystrom, M.L.2    Marshall, J.F.3
  • 12
    • 27644538315 scopus 로고    scopus 로고
    • Integrin-mediated activation of latent transforming growth factor beta
    • DOI 10.1007/s10555-005-5131-6
    • Sheppard D. Integrin-mediated activation of latent transforming growth factor beta. Cancer Metastasis Rev 2005; 24: 395-402. (Pubitemid 41569979)
    • (2005) Cancer and Metastasis Reviews , vol.24 , Issue.3 , pp. 395-402
    • Sheppard, D.1
  • 13
    • 35848929300 scopus 로고    scopus 로고
    • Correlations between the Sonic Hedgehog Pathway and basal cell carcinoma
    • DOI 10.1111/j.1365-4632.2007.03391.x
    • Lupi O. Correlations between the Sonic Hedgehog pathway and basal cell carcinoma. Int J Dermatol 2007; 46: 1113-1117 (Pubitemid 350055879)
    • (2007) International Journal of Dermatology , vol.46 , Issue.11 , pp. 1113-1117
    • Lupi, O.1
  • 14
    • 44849121993 scopus 로고    scopus 로고
    • Alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation
    • Marsh D, Dickinson S, Neill GW, Marshall JF, Hart IR, Thomas GJ. alpha vbeta 6 Integrin promotes the invasion of morphoeic basal cell carcinoma through stromal modulation. Cancer Res 2008; 68: 3295-3303
    • (2008) Cancer Res , vol.68 , pp. 3295-3303
    • Marsh, D.1    Dickinson, S.2    Neill, G.W.3    Marshall, J.F.4    Hart, I.R.5    Thomas, G.J.6
  • 15
    • 26444466006 scopus 로고    scopus 로고
    • Colorectal cancer progression: Integrin alphavbeta6 and the epithelial-mesenchymal transition (EMT)
    • Georgetown, Tex
    • Bates RC. Colorectal cancer progression: integrin alphavbeta6 and the epithelial-mesenchymal transition (EMT). Cell cycle Georgetown, Tex 2005; 4: 1350-1352
    • (2005) Cell Cycle , vol.4 , pp. 1350-1352
    • Bates, R.C.1
  • 16
    • 25144451812 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition (EMT) and colorectal cancer progression
    • Bates RC, Mercurio AM. The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. Cancer Biol Ther 2005; 4: 365-370 (Pubitemid 41351251)
    • (2005) Cancer Biology and Therapy , vol.4 , Issue.4 , pp. 365-370
    • Bates, R.C.1    Mercurio, A.M.2
  • 17
    • 43649083202 scopus 로고    scopus 로고
    • Integrin alpha v beta 6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver
    • Yang GY, Xu KS, Pan ZQ, Zhang ZY, Mi YT, Wang JS, et al. Integrin alpha v beta 6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver. Cancer Sci 2008; 99: 879-887
    • (2008) Cancer Sci , vol.99 , pp. 879-887
    • Yang, G.Y.1    Xu, K.S.2    Pan, Z.Q.3    Zhang, Z.Y.4    Mi, Y.T.5    Wang, J.S.6
  • 18
    • 0142211316 scopus 로고    scopus 로고
    • Alphavbeta6-Fyn signaling promotes oral cancer progression
    • Li X, Yang Y, Hu Y, Dang D, Regezi J, Schmidt BL, et al. Alphavbeta6-Fyn signaling promotes oral cancer progression. The J Biol Chem 2003; 278: 41646-41653
    • (2003) The J Biol Chem , vol.278 , pp. 41646-41653
    • Li, X.1    Yang, Y.2    Hu, Y.3    Dang, D.4    Regezi, J.5    Schmidt, B.L.6
  • 19
    • 61449094945 scopus 로고    scopus 로고
    • The role of the integrin alpha v beta6 in regulating the epithelial to mesenchymal transition in oral cancer
    • Ramos DM, Dang D, Sadler S. The role of the integrin alpha v beta6 in regulating the epithelial to mesenchymal transition in oral cancer. Anticancer Res 2009; 29: 125-130
    • (2009) Anticancer Res , vol.29 , pp. 125-130
    • Ramos, D.M.1    Dang, D.2    Sadler, S.3
  • 20
    • 0036123185 scopus 로고    scopus 로고
    • Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade
    • Ahmed N, Pansino F, Clyde R, Murthi P, Quinn MA, Rice GE, et al. Overexpression of alpha(v)beta6 integrin in serous epithelial ovarian cancer regulates extracellular matrix degradation via the plasminogen activation cascade. Carcinogenesis 2002; 23: 237-244
    • (2002) Carcinogenesis , vol.23 , pp. 237-244
    • Ahmed, N.1    Pansino, F.2    Clyde, R.3    Murthi, P.4    Quinn, M.A.5    Rice, G.E.6
  • 21
    • 0036799740 scopus 로고    scopus 로고
    • Alpha(v)beta(6) integrin-A marker for the malignant potential of epithelial ovarian cancer
    • Ahmed N, Riley C, Rice GE, Quinn MA, Baker MS. Alpha(v)beta(6) integrin-A marker for the malignant potential of epithelial ovarian cancer. J Histochem Cytochem 2002; 50: 1371-1380
    • (2002) J Histochem Cytochem , vol.50 , pp. 1371-1380
    • Ahmed, N.1    Riley, C.2    Rice, G.E.3    Quinn, M.A.4    Baker, M.S.5
  • 23
    • 0033082311 scopus 로고    scopus 로고
    • Altered expression of transforming growth factor-beta ligands and receptors in primary and recurrent ovarian carcinoma
    • DOI 10.1002/(SICI)1097-0142(19990201)85:3<658::AID-CNCR16>3.0.CO;2- M
    • Bristow RE, Baldwin RL, Yamada SD, Korc M, Karlan BY. Altered expression of transforming growth factor-beta ligands and receptors in primary and recurrent ovarian carcinoma. Cancer 1999; 85: 658-668 (Pubitemid 29075287)
    • (1999) Cancer , vol.85 , Issue.3 , pp. 658-668
    • Bristow, R.E.1    Baldwin, R.L.2    Yamada, S.D.3    Korc, M.4    Karlan, B.Y.5
  • 24
    • 4644324446 scopus 로고    scopus 로고
    • 6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro
    • DOI 10.1111/j.1365-2559.2004.01919.x
    • Sipos B, Hahn D, Carceller A, Piulats J, Hedderich J, Kalthoff H, et al. Immunohistochemical screening for beta6-integrin subunit expression in adenocarcinomas using a novel monoclonal antibody reveals strong up-regulation in pancreatic ductal adenocarcinomas in vivo and in vitro. Histopathol 2004; 45: 226-236 (Pubitemid 39279179)
    • (2004) Histopathology , vol.45 , Issue.3 , pp. 226-236
    • Sipos, B.1    Hahn, D.2    Carceller, A.3    Piulats, J.4    Hedderich, J.5    Kalthoff, H.6    Goodman, S.L.7    Kosmahl, M.8    Kloppel, G.9
  • 26
    • 38149020651 scopus 로고    scopus 로고
    • Integrin alphanvbeta6 acts as a prognostic indicator in gastric carcinoma
    • Royal College of Radiologists (Great Britain)
    • Zhang ZY, Xu KS, Wang JS, Yang GY, Wang W, Wang JY, et al. Integrin alphanvbeta6 acts as a prognostic indicator in gastric carcinoma. Clin Oncol (Royal College of Radiologists (Great Britain)) 2008; 20: 61-66
    • (2008) Clin Oncol , vol.20 , pp. 61-66
    • Zhang, Z.Y.1    Xu, K.S.2    Wang, J.S.3    Yang, G.Y.4    Wang, W.5    Wang, J.Y.6
  • 27
    • 33646552395 scopus 로고    scopus 로고
    • Reciprocal interactions between adhesion receptor signaling and MMP regulation
    • Munshi HG, Stack MS. Reciprocal interactions between adhesion receptor signaling and MMP regulation. Cancer Metastasis Rev 2006; 25: 45-56.
    • (2006) Cancer Metastasis Rev , vol.25 , pp. 45-56
    • Munshi, H.G.1    Stack, M.S.2
  • 28
    • 36249028068 scopus 로고    scopus 로고
    • The 120 kDa cell-binding fragment of fibronectin up-regulates migration of alphavbeta6-expressing cells by increasing matrix metalloproteinase-2 and -9 secretion
    • Al-Hazmi N, Thomas GJ, Speight PM, Whawell SA. The 120 kDa cell-binding fragment of fibronectin up-regulates migration of alphavbeta6-expressing cells by increasing matrix metalloproteinase-2 and -9 secretion. Eur J Oral Sci 2007; 115: 454-458
    • (2007) Eur J Oral Sci , vol.115 , pp. 454-458
    • Al-Hazmi, N.1    Thomas, G.J.2    Speight, P.M.3    Whawell, S.A.4
  • 30
    • 2942729679 scopus 로고    scopus 로고
    • The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9
    • Morgan MR, Thomas GJ, Russell A, Hart IR, Marshall JF. The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9. J Biol Chem 2004; 279: 26533-26539
    • (2004) J Biol Chem , vol.279 , pp. 26533-26539
    • Morgan, M.R.1    Thomas, G.J.2    Russell, A.3    Hart, I.R.4    Marshall, J.F.5
  • 31
    • 0347916989 scopus 로고    scopus 로고
    • Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer
    • Impola U, Uitto VJ, Hietanen J, Hakkinen L, Zhang L, Larjava H, et al. Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer. J Pathol 2004; 202: 14-22.
    • (2004) J Pathol , vol.202 , pp. 14-22
    • Impola, U.1    Uitto, V.J.2    Hietanen, J.3    Hakkinen, L.4    Zhang, L.5    Larjava, H.6
  • 32
    • 0037037304 scopus 로고    scopus 로고
    • Binding of TGFbeta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells
    • Thomas GJ, Hart IR, Speight PM, Marshall JF. Binding of TGFbeta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells. Br J Cancer 2002; 87: 859-867
    • (2002) Br J Cancer , vol.87 , pp. 859-867
    • Thomas, G.J.1    Hart, I.R.2    Speight, P.M.3    Marshall, J.F.4
  • 33
    • 0036253137 scopus 로고    scopus 로고
    • Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma
    • DOI 10.1016/S0945-053X(02)00002-1, PII S0945053X02000021
    • Ramos DM, But M, Regezi J, Schmidt BL, Atakilit A, Dang D, et al. Expression of integrin beta 6 enhances invasive behavior in oral squamous cell carcinoma. Matrix Biol 2002; 21: 297-307. (Pubitemid 34497020)
    • (2002) Matrix Biology , vol.21 , Issue.3 , pp. 297-307
    • Ramos, D.M.1    But, M.2    Regezi, J.3    Schmidt, B.L.4    Atakilit, A.5    Dang, D.6    Ellis, D.7    Jordan, R.8    Li, X.9
  • 34
    • 0035354344 scopus 로고    scopus 로고
    • AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9
    • DOI 10.1002/1097-0215(20010601)92:5<641::AID-IJC1243>3.0.CO;2-P
    • Thomas GJ, Lewis MP, Hart IR, Marshall JF, Speight PM. AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9. Int J Cancer 2001; 92: 641-650 (Pubitemid 32385704)
    • (2001) International Journal of Cancer , vol.92 , Issue.5 , pp. 641-650
    • Thomas, G.J.1    Lewis, M.P.2    Hart, I.R.3    Marshall, J.F.4    Speight, P.M.5
  • 35
    • 0036605068 scopus 로고    scopus 로고
    • Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit
    • DOI 10.1002/ijc.10397
    • Niu J, Dorahy DJ, Gu X, Scott RJ, Draganic B, Ahmed N, et al. Integrin expression in colon cancer cells is regulated by the cytoplasmic domain of the beta6 integrin subunit. Int J Cancer 2002; 99: 529-537 (Pubitemid 34461605)
    • (2002) International Journal of Cancer , vol.99 , Issue.4 , pp. 529-537
    • Niu, J.1    Dorahy, D.J.2    Gu, X.3    Scott, R.J.4    Draganic, B.5    Ahmed, N.6    Agrez, M.V.7
  • 36
    • 49049110677 scopus 로고    scopus 로고
    • Integrins and the activation of latent transforming growth factor beta1 - An intimate relationship
    • Wipff PJ, Hinz B. Integrins and the activation of latent transforming growth factor beta1 - an intimate relationship. Eur J Cell Biol 2008; 87: 601-615
    • (2008) Eur J Cell Biol , vol.87 , pp. 601-615
    • Wipff, P.J.1    Hinz, B.2
  • 37
    • 2942653435 scopus 로고    scopus 로고
    • Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1
    • Annes JP, Chen Y, Munger JS, Rifkin DB. Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1. J Cell Biol 2004; 165: 723-734
    • (2004) J Cell Biol , vol.165 , pp. 723-734
    • Annes, J.P.1    Chen, Y.2    Munger, J.S.3    Rifkin, D.B.4
  • 38
    • 0033524949 scopus 로고    scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis
    • Munger JS, Huang X, Kawakatsu H, Griffiths MJ, Dalton SL, Wu J, et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 1999; 96: 319-328
    • (1999) Cell , vol.96 , pp. 319-328
    • Munger, J.S.1    Huang, X.2    Kawakatsu, H.3    Griffiths, M.J.4    Dalton, S.L.5    Wu, J.6
  • 39
    • 0031670654 scopus 로고    scopus 로고
    • Interactions between growth factors and integrins: Latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1
    • Munger JS, Harpel JG, Giancotti FG, Rifkin DB. Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1. Mol Biol Cell 1998; 9: 2627-2638
    • (1998) Mol Biol Cell , vol.9 , pp. 2627-2638
    • Munger, J.S.1    Harpel, J.G.2    Giancotti, F.G.3    Rifkin, D.B.4
  • 40
    • 0036056156 scopus 로고    scopus 로고
    • Cancer cell motility-on the road from c-erbB-2 receptor steered signaling to actin reorganization
    • Feldner JC, Brandt BH. Cancer cell motility-on the road from c-erbB-2 receptor steered signaling to actin reorganization. Exp Cell Res 2002; 272: 93-108.
    • (2002) Exp Cell Res , vol.272 , pp. 93-108
    • Feldner, J.C.1    Brandt, B.H.2
  • 41
    • 23844488162 scopus 로고    scopus 로고
    • Regulation of cancer cell motility through actin reorganization
    • DOI 10.1111/j.1349-7006.2005.00062.x
    • Yamazaki D, Kurisu S, Takenawa T. Regulation of cancer cell motility through actin reorganization. Cancer Sci 2005; 96: 379-386 (Pubitemid 41179738)
    • (2005) Cancer Science , vol.96 , Issue.7 , pp. 379-386
    • Yamazaki, D.1    Kurisu, S.2    Takenawa, T.3
  • 43
    • 34347230941 scopus 로고    scopus 로고
    • HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6
    • DOI 10.1158/0008-5472.CAN-07-0318
    • Ramsay AG, Keppler MD, Jazayeri M, Thomas GJ, Parsons M, Violette S, et al. HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6. Cancer Res 2007; 67: 5275-5284 (Pubitemid 46997266)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5275-5284
    • Ramsay, A.G.1    Keppler, M.D.2    Jazayeri, M.3    Thomas, G.J.4    Parsons, M.5    Violette, S.6    Weinreb, P.7    Hart, I.R.8    Marshall, J.F.9
  • 44
    • 56149094041 scopus 로고    scopus 로고
    • Endocytosis and cancer: An 'insider' network with dangerous liaisons
    • Copenhagen, Denmark
    • Lanzetti L, Di Fiore PP. Endocytosis and cancer: an 'insider' network with dangerous liaisons. Traffic (Copenhagen, Denmark) 2008; 9: 2011-2021
    • (2008) Traffic , vol.9 , pp. 2011-2021
    • Lanzetti, L.1    Di Fiore, P.P.2
  • 45
    • 34548007871 scopus 로고    scopus 로고
    • Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: Generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomography
    • Hausner SH, DiCara D, Marik J, Marshall JF, Sutcliffe JL. Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomography. Cancer Res 2007; 67: 7833-7840
    • (2007) Cancer Res , vol.67 , pp. 7833-7840
    • Hausner, S.H.1    DiCara, D.2    Marik, J.3    Marshall, J.F.4    Sutcliffe, J.L.5
  • 47
    • 45049086748 scopus 로고    scopus 로고
    • Signaling and regulatory mechanisms of integrin alphavbeta6 on the apoptosis of colon cancer cells
    • Zhao-Yang Z, Ke-Sen X, Qing-Si H, Wei-Bo N, Jia-Yong W, Yue-Tang M, et al. Signaling and regulatory mechanisms of integrin alphavbeta6 on the apoptosis of colon cancer cells. Cancer Lett 2008; 266: 209-215
    • (2008) Cancer Lett , vol.266 , pp. 209-215
    • Zhao-Yang, Z.1    Ke-Sen, X.2    Qing-Si, H.3    Wei-Bo, N.4    Jia-Yong, W.5    Yue-Tang, M.6
  • 48
    • 50249174510 scopus 로고    scopus 로고
    • Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus
    • Kogelberg H, Tolner B, Thomas GJ, Di Cara D, Minogue S, Ramesh B, et al. Engineering a single-chain Fv antibody to alpha v beta 6 integrin using the specificity-determining loop of a foot-and-mouth disease virus. J Mol Biol 2008; 382: 385-401.
    • (2008) J Mol Biol , vol.382 , pp. 385-401
    • Kogelberg, H.1    Tolner, B.2    Thomas, G.J.3    Di Cara, D.4    Minogue, S.5    Ramesh, B.6
  • 49
    • 34347359740 scopus 로고    scopus 로고
    • Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival
    • Hazelbag S, Kenter GG, Gorter A, Dreef EJ, Koopman LA, Violette SM, et al. Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival. J Pathol 2007; 212: 316-324
    • (2007) J Pathol , vol.212 , pp. 316-324
    • Hazelbag, S.1    Kenter, G.G.2    Gorter, A.3    Dreef, E.J.4    Koopman, L.A.5    Violette, S.M.6
  • 50
    • 0031079837 scopus 로고    scopus 로고
    • Changes in the expression of alpha(v) integrins in oral squamous cell carcinomas
    • Jones J, Watt FM, Speight PM. Changes in the expression of alpha v integrins in oral squamous cell carcinomas. J Oral Pathol Med 1997; 26: 63-68 (Pubitemid 27157727)
    • (1997) Journal of Oral Pathology and Medicine , vol.26 , Issue.2 , pp. 63-68
    • Jones, J.1    Watt, F.M.2    Speight, P.M.3
  • 52
    • 0033660302 scopus 로고    scopus 로고
    • Significance of alpha 9 beta 1 and alpha v beta 6 integrin expression in breast carcinoma
    • Tokyo, Japan
    • Arihiro K, Kaneko M, Fujii S, Inai K, Yokosaki Y. Significance of alpha 9 beta 1 and alpha v beta 6 integrin expression in breast carcinoma. Breast Cancer (Tokyo, Japan) 2000; 7: 19-26.
    • (2000) Breast Cancer , vol.7 , pp. 19-26
    • Arihiro, K.1    Kaneko, M.2    Fujii, S.3    Inai, K.4    Yokosaki, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.