Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by β1 integrins

Journal of Cell Biology

Volumn 166, Issue 3, 2004, Pages 407-418

  Goel, Hira Lal ^a   Fornaro, Mara ^b   Moro, Loredana ^b   Teider, Natalia ^a   Rhim, Johng S ^c   King, Michael ^a   Languino, Lucia R ^a,b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Gab1; IRS 1; Laminin; PI 3 kinase; Prostate

Indexed keywords

BETA1 INTEGRIN; BINDING PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; INSULIN RECEPTOR SUBSTRATE 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; RIBOZYME; SOMATOMEDIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; PROSTATE TUMOR; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; TUMOR GROWTH;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD29; CELL ADHESION; CELL DIVISION; HUMANS; LAMININ; MALE; MICE; PHOSPHOPROTEINS; PROSTATE; PROSTATIC NEOPLASMS; PROTEINS; RECEPTORS, SOMATOMEDIN; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 3543127788     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200403003     Document Type: Article

References (57)

1. Baserga, R. 2000. The contradictions of the insulin-like growth factor 1 receptor. Oncogene. 19:5574-5581.
2. Bello-DeOcampo, D., H.K. Kleinman, N.D. Deocampo, and M.M. Webber. 2001. Laminin-1 and α6β1 integrin regulate acinar morphogenesis of normal and malignant human prostate epithelial cells. Prostate. 46:142-153.
3. 1 integrin is essential for teratoma growth and angiogenesis. J. Cell Biol. 139:265-278.
4. Bouvard, D., C. Brakebusch, E. Gustafsson, A. Aszodi, T. Bengtsson, A. Berna, and R. Fassler. 2001. Functional consequences of integrin gene mutations in mice. Circ. Res. 89:211-223.
5. Brar, P.K., B.L. Dalkin, C. Weyer, K. Sallam, I. Virtanen, and R.B. Nagle. 2003. Laminin α-1, α-3, and α-5 chain expression in human prepubertal benign prostate glands and adult benign and malignant prostate glands. Prostate. 55:65-70.
6. Brown, P.J., and R.L. Juliano. 1985. Selective inhibition of fibronectin-mediated cell adhesion by monoclonal antibodies to a cell-surface glycoprotein. Science. 228:1448-1450.
7. Burfeind, P., C.L. Chernicky, F. Rininsland, and J. Ilan. 1996. Antisense RNA to the type I insulin-like growth factor receptor suppresses tumor growth and prevents invasion by rat prostate cancer cells in vivo. Proc. Natl. Acad. Sci. USA. 93:7263-7268.
8. Colognato, H., and P.D. Yurchenco. 2000. Form and function: the laminin family of heterotrimers. Dev. Dyn. 218:213-234.
9. 1 integrin. J. Cell Biol. 115:843-850.
10. 4 integrins in human prostate cancer progression. Cancer Metastasis Rev. 14:219-228.
11. Damsky, C.H., and D. Ilic. 2002. Integrin signaling: it's where the action is. Curr. Opin. Cell Biol. 14:594-602.
12. Davis, T.L., A.E. Cress, B.L. Dalkin, and R.B. Nagle. 2001. Unique expression pattern of the α6β4 integrin and laminin-5 in human prostate carcinoma. Prostate. 46:240-248.
13. Dunn, S.E., M. Ehrlich, N.J. Sharp, K. Reiss, G. Solomon, R. Hawkins, R. Baserga, and J.C. Barrett. 1998. A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res. 58:3353-3361.
14. Ekblom, P., P. Lonai, and J.F. Talts. 2003. Expression and biological role of laminin-1. Matrix Biol. 22:35-47.
15. 1 is involved in kidney tubulogenesis in vitro. J. Cell Sci. 109:2801-2810.
16. Fornaro, M., and L.R. Languino. 1997. Alternatively spliced variants: a new view of the integrin cytoplasmic domain. Matrix Biol. 16:185-193.
17. 1C integrin in prostatic adenocarcinoma. J. Clin. Invest. 103:321-329.
18. 1A integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/mitogen-activated protein kinase pathways. Mol. Biol. Cell. 11:2235-2249.
19. 1C integrin cytoplasmic domain variant. Exp. Mol. Pathol. 70:275-280.
20. Fornaro, M., T. Manes, and L.R. Languino. 2001b. Integrins and prostate cancer metastases. Cancer Metastasis Rev. 20:321-331.
21. Fornaro, M., J. Plescia, S. Chheang, G. Tallini, Y.-M. Zhu, M. King, D.C. Altieri, and L.R. Languino. 2003. Fibronectin protects prostate cancer cells from tumor necrosis factor alpha-induced apoptosis via the AKT/Survivin pathway. J. Biol. Chem. 278:50402-50411.
22. Fuchs, M.E., M.K. Brawer, M.A. Rennels, and R.B. Nagle. 1989. The relationship of basement membrane to histologic grade of human prostatic carcinoma. Mod. Pathol. 2:105-111.
23. Gu, H., and B.G. Neel. 2003. The "Gab" in signal transduction. Trends Cell Biol. 13:122-130.
24. Hara, K., K. Yonezawa, H. Sakaue, A. Ando, K. Kotani, T. Kitamura, Y. Kitamura, H. Ueda, L. Stephens, T.R. Jackson, et al. 1994. 1- phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc. Natl. Acad. Sci. USA. 91:7415-7419.
25. Holgado-Madruga, M., and A.J. Wong. 2003. Gab1 is an integrator of cell death versus cell survival signals in oxidative stress. Mol. Cell. Biol. 23:4471-4484.
26. Hynes, R.O. 2002. Integrins: bidirectional, allosteric signaling machines. Cell. 110:673-687.
27. 1 integrins in tumors. Semin. Cancer Biol. 4:277-283.
28. 1 subunit with a variant cytoplasmic domain. J. Biol. Chem. 267:7116-7120.
29. Languino, L.R., J. Plescia, A. Duperray, A.A. Brian, E.F. Plow, J.E. Geltosky, and D.C. Altieri. 1993. Fibrinogen mediates leukocyte adhesion to vascular endothelium through an ICAM-1 dependent pathway. Cell. 73:1423-1434.
30. LeRoith, D., and C.T. Roberts, Jr. 2003. The insulin-like growth factor system and cancer. Cancer Lett. 195:127-137.
31. Malinda, K.M., and H.K. Kleinman. 1996. The laminins. Int. J. Biochem. Cell Biol. 28:957-959.
32. 3 integrin expression up-regulates cdc2, which modulates cell migration. J. Cell Biol. 161:817-826.
33. 1C integrin in breast carcinomas correlates with high proliferative fraction, high histological grade, and larger size. Am. J. Pathol. 156:169-174.
34. 1 subunit react with proteins in vertebrates, invertebrates, and fungi. J. Cell Biol. 106:1765-1772.
35. Mercurio, A.M. 1995. Laminin receptors: achieving specificity through cooperation. Trends Cell Biol. 5:419-423.
36. Moro, L., E. Perlino, E. Marra, L.R. Languino, and M. Greco. 2004. Regulation of β1C and β1A integrin expression in prostate carcinoma cells. J. Biol. Chem. 279:1692-1702.
37. Myers, M.G., Jr., R. Mendez, P. Shi, J.H. Pierce, R. Rhoads, and M.F. White. 1998. The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling. J. Biol. Chem. 273:26908-26914.
38. Neel, B.G., H. Gu, and L. Pao. 2003. The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 28:284-293.
39. Nerlich, A.G., A. Lebeau, H.G. Hagedorn, U. Sauer, and E.D. Schleicher. 1998. Morphological aspects of altered basement membrane metabolism in invasive carcinomas of the breast and the larynx. Anticancer Res. 18:3515-3520.
40. Parda, D.S., P.J. Thraves, M.R. Kuettel, M.S. Lee, P. Arnstein, M.E. Kaighn, J.S. Rhim, and A. Dritschilo. 1993. Neoplastic transformation of a human prostate epithelial cell line by the v-Ki-ras oncogene. Prostate. 23:91-98.
41. Parise, L.V., J. Lee, and R.L. Juliano. 2000. New aspects of integrin signaling in cancer. Semin. Cancer Biol. 10:407-414.
42. Peehl, D.M., S.T. Wong, R.G. Seller, S. Jin, and J.S. Rhim. 1997. Loss of response to epidermal growth factor and retinoic acid accompanies the transformation of human prostatic epithelial cells to tumorigenicity with v-Ki-ras. Carcinogenesis. 18:1643-1650.
43. Reiss, K., C. D'Ambrosio, X. Tu, C. Tu, and R. Baserga. 1998. Inhibition of tumor growth by a dominant negative mutant of the insulin-like growth factor I receptor with a bystander effect. Clin. Cancer Res. 4:2647-2655.
44. Reiss, K., J.Y. Wang, G. Romano, F.B. Furnari, W.K. Cavenee, A. Morrione, X. Tu, and R. Baserga. 2000. IGF-1 receptor signaling in a prostatic cancer cell line with a PTEN mutation. Oncogene. 19:2687-2694.
45. Reiss, K., J.Y. Wang, G. Romano, X. Tu, F. Peruzzi, and R. Baserga. 2001. Mechanisms of regulation of cell adhesion and motility by insulin receptor substrate-1 in prostate cancer cells. Oncogene. 20:490-500.
46. Retta, S.F., F. Balzac, P. Ferraris, A.M. Belkin, R. Fassler, M.J. Humphries, G. De Leo, L. Silengo, and G. Tarone. 1998. β1-integrin cytoplasmic subdomains involved in dominant negative function. Mol. Biol. Cell. 9:715-731.
47. Sell, C., G. Dumenil, C. Deveaud, M. Miura, D. Coppola, T. DeAngelis, R. Rubin, A. Efstratiadis, and R. Baserga. 1994. Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts. Mol. Cell. Biol. 14:3604-3612.
48. 6 subunit. J. Cell Biol. 123:1017-1025.
49. Sonnenberg, A., H. Janssen, F. Hogervorst, J. Calafat, and J. Hilgers. 1987. A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody. J. Biol. Chem. 262:10376-10383.
50. Surmacz, E. 2003. Growth factor receptors as therapeutic targets: strategies to inhibit the insulin-like growth factor I receptor. Oncogene. 22:6589-6597.
51. Tai, Y.T., K. Podar, L. Catley, Y.H. Tseng, M. Akiyama, R. Shringarpure, R. Burger, T. Hideshima, D. Chauhan, N. Mitsiades, et al. 2003. Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of β1-integrin and phosphatidylinositol 3′-kinase/AKT signaling. Cancer Res. 63:5850-5858.
52. Tsiper, M.V., and P.D. Yurchenco. 2002. Laminin assembles into separate basement membrane and fibrillar matrices in Schwann cells. J. Cell Sci. 115:1005-1015.
53. Valentinis, B., and R. Baserga. 2001. IGF-I receptor signalling in transformation and differentiation. Mol. Pathol. 54:133-137.
54. Winnay, J.N., J.C. Bruning, D.J. Burks, and C.R. Kahn. 2000. Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts. J. Biol. Chem. 275:10545-10550.
55. Yamada, K.M., and S. Even-Ram. 2002. Integrin regulation of growth factor receptors. Nat. Cell Biol. 4:E75-E76.
56. Zhang, S.Q., W.G. Tsiaras, T. Araki, G. Wen, L. Minichiello, R. Klein, and B.G. Neel. 2002. Receptor-specific regulation of phosphatidylinositol 3′-kinase activation by the protein tyrosine phosphatase Shp2. Mol. Cell. Biol. 22:4062-4072.
57. Zheng, B., and D.R. Clemmons. 1998. Blocking ligand occupancy of the αVβ3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells. Proc. Natl. Acad. Sci. USA. 95:11217-11222.