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Volumn 2015, Issue , 2015, Pages

Therapeutic potential of IL-17-mediated signaling pathway in autoimmune liver diseases

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR;

EID: 84935035163     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2015/436450     Document Type: Review
Times cited : (28)

References (131)
  • 1
    • 0031879659 scopus 로고    scopus 로고
    • Primary biliary cirrhosisautoimmune hepatitis overlap syndrome: Clinical features and response to therapy
    • O. Chazouillères, D. Wendum, L. Serfaty, S. Montembault, O. Rosmorduc, and R. Poupon, "Primary biliary cirrhosisautoimmune hepatitis overlap syndrome: clinical features and response to therapy, " Hepatology, vol. 28, no. 2, pp. 296-301, 1998.
    • (1998) Hepatology , vol.28 , Issue.2 , pp. 296-301
    • Chazouillères, O.1    Wendum, D.2    Serfaty, L.3    Montembault, S.4    Rosmorduc, O.5    Poupon, R.6
  • 2
    • 78751572618 scopus 로고    scopus 로고
    • Overlap syndromes: The International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue
    • K. M. Boberg, R. W. Chapman, G. M. Hirschfield, A. W. Lohse, M. P. Manns, and E. Schrumpf, "Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue, " Journal of Hepatology, vol. 54, no. 2, pp. 374-385, 2011.
    • (2011) Journal of Hepatology , vol.54 , Issue.2 , pp. 374-385
    • Boberg, K.M.1    Chapman, R.W.2    Hirschfield, G.M.3    Lohse, A.W.4    Manns, M.P.5    Schrumpf, E.6
  • 3
    • 38749143286 scopus 로고    scopus 로고
    • Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
    • J. S. Tzartos, M. A. Friese, M. J. Craner et al., "Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis, " The American Journal of Pathology, vol. 172, no. 1, pp. 146-155, 2008.
    • (2008) The American Journal of Pathology , vol.172 , Issue.1 , pp. 146-155
    • Tzartos, J.S.1    Friese, M.A.2    Craner, M.J.3
  • 4
    • 42149087160 scopus 로고    scopus 로고
    • Psoriasis vulgaris lesions contain discrete populations ofTh1 and Th17 T cells
    • M. A. Lowes, T. Kikuchi, J. Fuentes-Duculan et al., "Psoriasis vulgaris lesions contain discrete populations ofTh1 and Th17 T cells, " Journal of Investigative Dermatology, vol. 128, no. 5, pp. 1207-1211, 2008.
    • (2008) Journal of Investigative Dermatology , vol.128 , Issue.5 , pp. 1207-1211
    • Lowes, M.A.1    Kikuchi, T.2    Fuentes-Duculan, J.3
  • 6
    • 0027215897 scopus 로고
    • CTLA-8, cloned from an activated T cell, bearing AUrich messenger RNA instability sequences, and homologous to aHerpesvirus saimiri gene
    • E. Rouvier, M.-F. Luciani, M.-G. Mattei, F. Denizot, and P. Golstein, "CTLA-8, cloned from an activated T cell, bearing AUrich messenger RNA instability sequences, and homologous to aHerpesvirus saimiri gene, " Journal of Immunology, vol. 150, no. 12, pp. 5445-5456, 1993.
    • (1993) Journal of Immunology , vol.150 , Issue.12 , pp. 5445-5456
    • Rouvier, E.1    Luciani, M.-F.2    Mattei, M.-G.3    Denizot, F.4    Golstein, P.5
  • 7
    • 0037100263 scopus 로고    scopus 로고
    • Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis
    • T. Starnes, H. E. Broxmeyer, M. J. Robertson, and R. Hromas, "Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis, " The Journal of Immunology, vol. 169, no. 2, pp. 642-646, 2002.
    • (2002) The Journal of Immunology , vol.169 , Issue.2 , pp. 642-646
    • Starnes, T.1    Broxmeyer, H.E.2    Robertson, M.J.3    Hromas, R.4
  • 8
    • 0035846998 scopus 로고    scopus 로고
    • IL-17E, a novel proinflammatory lig and for the IL-17 receptor homolog IL-17Rh1
    • J. Lee, W.-H. Ho, M. Maruoka et al., "IL-17E, a novel proinflammatory lig and for the IL-17 receptor homolog IL-17Rh1, " The Journal of Biological Chemistry, vol. 276, no. 2, pp. 1660-1664, 2001.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.2 , pp. 1660-1664
    • Lee, J.1    Ho, W.-H.2    Maruoka, M.3
  • 9
    • 17944368518 scopus 로고    scopus 로고
    • IL-17s adopt a cystine knot fold: Structure and activity of a novel cytokine, IL-17F, and implications for receptor binding
    • S. G. Hymowitz, E. H. Filvaroff, J. Yin et al., "IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding, " The EMBO Journal, vol. 20, no. 19, pp. 5332-5341, 2001.
    • (2001) The EMBO Journal , vol.20 , Issue.19 , pp. 5332-5341
    • Hymowitz, S.G.1    Filvaroff, E.H.2    Yin, J.3
  • 10
    • 15844402155 scopus 로고    scopus 로고
    • T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
    • F. Fossiez, O. Djossou, P. Chomarat et al., "T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines, " Journal of Experimental Medicine, vol. 183, no. 6, pp. 2593-2603, 1996.
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.6 , pp. 2593-2603
    • Fossiez, F.1    Djossou, O.2    Chomarat, P.3
  • 11
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • S. C. Liang, X.-Y. Tan, D. P. Luxenberg et al., "Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides, " The Journal of Experimental Medicine, vol. 203, no. 10, pp. 2271-2279, 2006.
    • (2006) The Journal of Experimental Medicine , vol.203 , Issue.10 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.-Y.2    Luxenberg, D.P.3
  • 12
    • 0031691282 scopus 로고    scopus 로고
    • Interleukin-17 and interferon-synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
    • M. B. M. Teunissen, C. W. Koomen, R. de Waal Malefyt, E. A. Wierenga, and J. D. Bos, "Interleukin-17 and interferon-synergize in the enhancement of proinflammatory cytokine production by human keratinocytes, " Journal of Investigative Dermatology, vol. 111, no. 4, pp. 645-649, 1998.
    • (1998) Journal of Investigative Dermatology , vol.111 , Issue.4 , pp. 645-649
    • Teunissen, M.B.M.1    Koomen, C.W.2    Malefyt, W.R.D.3    Wierenga, E.A.4    Bos, J.D.5
  • 13
    • 33747662347 scopus 로고    scopus 로고
    • Identification of common transcriptional regulatory elements in interleukin-17 target genes
    • F. Shen, Z. Hu, J. Goswami, and S. L. Gaffen, "Identification of common transcriptional regulatory elements in interleukin-17 target genes, " The Journal of Biological Chemistry, vol. 281, no. 34, pp. 24138-24148, 2006.
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.34 , pp. 24138-24148
    • Shen, F.1    Hu, Z.2    Goswami, J.3    Gaffen, S.L.4
  • 15
    • 0038035216 scopus 로고    scopus 로고
    • Tcell-derived interleukin-17 regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of the p38 mitogen-Activated protein kinase cascade. Role of distal sequences in the 3-untranslated region of COX-2 mRNA
    • W. H. Faour, A. Mancini, Q. W. He, and J. A. Di Battista, "Tcell-derived interleukin-17 regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of the p38 mitogen-Activated protein kinase cascade. Role of distal sequences in the 3-untranslated region of COX-2 mRNA, " The Journal of Biological Chemistry, vol. 278, no. 29, pp. 26897-26907, 2003.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.29 , pp. 26897-26907
    • Faour, W.H.1    Mancini, A.2    He, Q.W.3    Di Battista, J.A.4
  • 16
    • 0033557728 scopus 로고    scopus 로고
    • Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
    • M. Laan, Z.-H. Cui, H. Hoshino et al., "Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways, " The Journal of Immunology, vol. 162, no. 4, pp. 2347-2352, 1999.
    • (1999) The Journal of Immunology , vol.162 , Issue.4 , pp. 2347-2352
    • Laan, M.1    Cui, Z.-H.2    Hoshino, H.3
  • 17
    • 33745321276 scopus 로고    scopus 로고
    • IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
    • Y. Komiyama, S. Nakae, T. Matsuki et al., "IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis, " Journal of Immunology, vol. 177, no. 1, pp. 566-573, 2006.
    • (2006) Journal of Immunology , vol.177 , Issue.1 , pp. 566-573
    • Komiyama, Y.1    Nakae, S.2    Matsuki, T.3
  • 18
    • 63049138176 scopus 로고    scopus 로고
    • Th17 cells and IL-17 receptor signaling are essential formucosal host defense against oral c and idiasis
    • H. R. Conti, F. Shen, N. Nayyar et al., "Th17 cells and IL-17 receptor signaling are essential formucosal host defense against oral c and idiasis, " Journal of ExperimentalMedicine, vol. 206, no. 2, pp. 299-311, 2009.
    • (2009) Journal of ExperimentalMedicine , vol.206 , Issue.2 , pp. 299-311
    • Conti, H.R.1    Shen, F.2    Nayyar, N.3
  • 19
    • 67349242957 scopus 로고    scopus 로고
    • A pathogenic role of IL-17 at the early stage of corneal allograft rejection
    • H. Chen, W. Wang, H. Xie et al., "A pathogenic role of IL-17 at the early stage of corneal allograft rejection, " Transplant Immunology, vol. 21, no. 3, pp. 155-161, 2009.
    • (2009) Transplant Immunology , vol.21 , Issue.3 , pp. 155-161
    • Chen, H.1    Wang, W.2    Xie, H.3
  • 20
    • 36048968753 scopus 로고    scopus 로고
    • IL-17-dependent cellular immunity to collagen type v predisposes to obliterative bronchiolitis in human lung transplants
    • W. J. Burlingham, R. B. Love, E. Jankowska-Gan et al., "IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants, " The Journal of Clinical Investigation, vol. 117, no. 11, pp. 3498-3506, 2007.
    • (2007) The Journal of Clinical Investigation , vol.117 , Issue.11 , pp. 3498-3506
    • Burlingham, W.J.1    Love, R.B.2    Jankowska-Gan, E.3
  • 21
    • 70449530422 scopus 로고    scopus 로고
    • T helper 17 cells promote cytotoxic T cell activation in tumor immunity
    • N. Martin-Orozco, P. Muranski, Y. Chung et al., "T helper 17 cells promote cytotoxic T cell activation in tumor immunity, " Immunity, vol. 31, no. 5, pp. 787-798, 2009.
    • (2009) Immunity , vol.31 , Issue.5 , pp. 787-798
    • Martin-Orozco, N.1    Muranski, P.2    Chung, Y.3
  • 22
    • 0035887627 scopus 로고    scopus 로고
    • Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production
    • T. Starnes, M. J. Robertson, G. Sledge et al., "Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production, " Journal of Immunology, vol. 167, no. 8, pp. 4137-4140, 2001.
    • (2001) Journal of Immunology , vol.167 , Issue.8 , pp. 4137-4140
    • Starnes, T.1    Robertson, M.J.2    Sledge, G.3
  • 23
    • 34248574863 scopus 로고    scopus 로고
    • A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses
    • S. H. Chang and C. Dong, "A novel heterodimeric cytokine consisting of IL-17 and IL-17F regulates inflammatory responses, " Cell Research, vol. 17, no. 5, pp. 435-440, 2007.
    • (2007) Cell Research , vol.17 , Issue.5 , pp. 435-440
    • Chang, S.H.1    Dong, C.2
  • 24
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • S. Aggarwal, N. Ghilardi, M.-H. Xie, F. J. de Sauvage, and A. L. Gurney, "Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17, " Journal of Biological Chemistry, vol. 278, no. 3, pp. 1910-1914, 2003.
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.3 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.-H.3    De Sauvage, F.J.4    Gurney, A.L.5
  • 25
    • 33750505009 scopus 로고    scopus 로고
    • Interleukin-23 drives innate and T cell-mediated intestinal inflammation
    • S. Hue, P. Ahern, S. Buonocore et al., "Interleukin-23 drives innate and T cell-mediated intestinal inflammation, " Journal of Experimental Medicine, vol. 203, no. 11, pp. 2473-2483, 2006.
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.11 , pp. 2473-2483
    • Hue, S.1    Ahern, P.2    Buonocore, S.3
  • 26
    • 42649110747 scopus 로고    scopus 로고
    • Cutting edge: NKT cells constitutively express IL-23 receptor and RORt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion
    • A. V. Rachitskaya, A. M. Hansen, R. Horai et al., "Cutting edge: NKT cells constitutively express IL-23 receptor and RORt and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion, " Journal of Immunology, vol. 180, no. 8, pp. 5167-5171, 2008.
    • (2008) Journal of Immunology , vol.180 , Issue.8 , pp. 5167-5171
    • Rachitskaya, A.V.1    Hansen, A.M.2    Horai, R.3
  • 27
    • 33747089041 scopus 로고    scopus 로고
    • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
    • H. H. Uhlig, B. S. McKenzie, S. Hue et al., "Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology, " Immunity, vol. 25, no. 2, pp. 309-318, 2006.
    • (2006) Immunity , vol.25 , Issue.2 , pp. 309-318
    • Uhlig, H.H.1    McKenzie, B.S.2    Hue, S.3
  • 28
    • 77954143695 scopus 로고    scopus 로고
    • Innate IL-17-producing cells: The sentinels of the immune system
    • D. J. Cua and C. M. Tato, "Innate IL-17-producing cells: the sentinels of the immune system, " Nature Reviews Immunology, vol. 10, no. 7, pp. 479-489, 2010.
    • (2010) Nature Reviews Immunology , vol.10 , Issue.7 , pp. 479-489
    • Cua, D.J.1    Tato, C.M.2
  • 29
    • 68849084891 scopus 로고    scopus 로고
    • Structure and signalling in the IL-17 receptor family
    • S. L. Gaffen, "Structure and signalling in the IL-17 receptor family, " Nature Reviews Immunology, vol. 9, no. 8, pp. 556-567, 2009.
    • (2009) Nature Reviews Immunology , vol.9 , Issue.8 , pp. 556-567
    • Gaffen, S.L.1
  • 30
    • 58149231532 scopus 로고    scopus 로고
    • Differential roles of interleukin-17A and -17F in host defense againstmucoepithelial bacterial infection and allergic responses
    • H. Ishigame, S. Kakuta, T. Nagai et al., "Differential roles of interleukin-17A and -17F in host defense againstmucoepithelial bacterial infection and allergic responses, " Immunity, vol. 30, no. 1, pp. 108-119, 2009.
    • (2009) Immunity , vol.30 , Issue.1 , pp. 108-119
    • Ishigame, H.1    Kakuta, S.2    Nagai, T.3
  • 31
    • 33748429852 scopus 로고    scopus 로고
    • Role of interleukin-17F in chronic inflammatory and allergic lung disease
    • N. Hizawa, M. Kawaguchi, S.-K. Huang, and M. Nishimura, "Role of interleukin-17F in chronic inflammatory and allergic lung disease, " Clinical and Experimental Allergy, vol. 36, no. 9, pp. 1109-1114, 2006.
    • (2006) Clinical and Experimental Allergy , vol.36 , Issue.9 , pp. 1109-1114
    • Hizawa, N.1    Kawaguchi, M.2    Huang, S.-K.3    Nishimura, M.4
  • 32
    • 43549110961 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by IL-17F
    • X. O. Yang, S. H. Chang, H. Park et al., "Regulation of inflammatory responses by IL-17F, " Journal of Experimental Medicine, vol. 205, no. 5, pp. 1063-1075, 2008.
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.5 , pp. 1063-1075
    • Yang, X.O.1    Chang, S.H.2    Park, H.3
  • 33
    • 34547820890 scopus 로고    scopus 로고
    • IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-ActivatedTh2memory cells
    • Y.-H. Wang, P. Angkasekwinai, N. Lu et al., "IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-ActivatedTh2memory cells, "TheJournal of Experimental Medicine, vol. 204, no. 8, pp. 1837-1847, 2007.
    • (2007) TheJournal of Experimental Medicine , vol.204 , Issue.8 , pp. 1837-1847
    • Wang, Y.-H.1    Angkasekwinai, P.2    Lu, N.3
  • 34
    • 33845460525 scopus 로고    scopus 로고
    • Mechanism of interleukin-25 (IL-17E)-induced pulmonary inflammation and airways hyper-reactivity
    • Forbes et al
    • T. Sharkhuu, K. I. Matthaei, E. Forbes et al., "Mechanism of interleukin-25 (IL-17E)-induced pulmonary inflammation and airways hyper-reactivity, " Clinical and ExperimentalAllergy, vol. 36, no. 12, pp. 1575-1583, 2006.
    • (2006) Clinical and ExperimentalAllergy , vol.36 , Issue.12 , pp. 1575-1583
    • Sharkhuu, T.1    Matthaei E, K.I.2
  • 35
    • 67649213505 scopus 로고    scopus 로고
    • IL-25: A key requirement for the regulation of type-2 immunity
    • J. L. Barlow and A. N. J. McKenzie, "IL-25: a key requirement for the regulation of type-2 immunity, " BioFactors, vol. 35, no. 2, pp. 178-182, 2009.
    • (2009) BioFactors , vol.35 , Issue.2 , pp. 178-182
    • Barlow, J.L.1    McKenzie, A.N.J.2
  • 37
    • 77955499820 scopus 로고    scopus 로고
    • TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3CD127+ immune cells in spleen and mucosa
    • L. vanMaele, C. Carnoy, D. Cayet et al., "TLR5 signaling stimulates the innate production of IL-17 and IL-22 by CD3CD127+ immune cells in spleen and mucosa, " Journal of Immunology, vol. 185, no. 2, pp. 1177-1185, 2010.
    • (2010) Journal of Immunology , vol.185 , Issue.2 , pp. 1177-1185
    • Vanmaele, L.1    Carnoy, C.2    Cayet, D.3
  • 38
    • 57449114952 scopus 로고    scopus 로고
    • Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus
    • D. B. Holl and , R. A. Bojar, M. D. Farrar, and K. T. Holl and , "Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus, " FEMSMicrobiology Letters, vol. 290, no. 2, pp. 149-155, 2009.
    • (2009) FEMSMicrobiology Letters , vol.290 , Issue.2 , pp. 149-155
    • Holland, D.B.1    Bojar, R.A.2    Farrar, M.D.3    Holland, K.T.4
  • 39
    • 38449102562 scopus 로고    scopus 로고
    • IL-17B and IL-17C are associated with TNF-production and contribute to the exacerbation of inflammatory arthritis
    • Y. Yamaguchi, K. Fujio, H. Shoda et al., "IL-17B and IL-17C are associated with TNF-production and contribute to the exacerbation of inflammatory arthritis, " The Journal of Immunology, vol. 179, no. 10, pp. 7128-7136, 2007.
    • (2007) The Journal of Immunology , vol.179 , Issue.10 , pp. 7128-7136
    • Yamaguchi, Y.1    Fujio, K.2    Shoda, H.3
  • 40
    • 0029555301 scopus 로고
    • Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
    • Z. Yao, W. C. Fanslow, M. F. Seldin et al., "Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor, " Immunity, vol. 3, no. 6, pp. 811-821, 1995.
    • (1995) Immunity , vol.3 , Issue.6 , pp. 811-821
    • Yao, Z.1    Fanslow, W.C.2    Seldin, M.F.3
  • 41
    • 0031282513 scopus 로고    scopus 로고
    • Molecular characterization of the human interleukin (IL)-17 receptor
    • Z. Yao, M. K. Spriggs, J. M. J. Derry et al., "Molecular characterization of the human interleukin (IL)-17 receptor, " Cytokine, vol. 9, no. 11, pp. 794-800, 1997.
    • (1997) Cytokine , vol.9 , Issue.11 , pp. 794-800
    • Yao, Z.1    Spriggs, M.K.2    Derry, J.M.J.3
  • 42
    • 70450233404 scopus 로고    scopus 로고
    • Interleukin-25 expressed by brain capillary endothelial cells maintains bloodbrain barrier function in a protein kinase C-dependent manner
    • Y. Sonobe, H. Takeuchi, K. Kataoka et al., "Interleukin-25 expressed by brain capillary endothelial cells maintains bloodbrain barrier function in a protein kinase C-dependent manner, " The Journal of Biological Chemistry, vol. 284, no. 46, pp. 31834-31842, 2009.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.46 , pp. 31834-31842
    • Sonobe, Y.1    Takeuchi, H.2    Kataoka, K.3
  • 44
    • 58149289887 scopus 로고    scopus 로고
    • A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity
    • A. Terashima, H. Watarai, S. Inoue et al., "A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity, " Journal of Experimental Medicine, vol. 205, no. 12, pp. 2727-2733, 2008.
    • (2008) Journal of Experimental Medicine , vol.205 , Issue.12 , pp. 2727-2733
    • Terashima, A.1    Watarai, H.2    Inoue, S.3
  • 45
    • 56149091567 scopus 로고    scopus 로고
    • Identification of functional roles for both IL-17RB and IL-17RA inmediating IL-25-induced activities
    • E. A. Rickel, L. A. Siegel, P. Y. Bo-Rin et al., "Identification of functional roles for both IL-17RB and IL-17RA inmediating IL-25-induced activities, " The Journal of Immunology, vol. 181, no. 6, pp. 4299-4310, 2008.
    • (2008) The Journal of Immunology , vol.181 , Issue.6 , pp. 4299-4310
    • Rickel, E.A.1    Siegel, L.A.2    Bo-Rin, P.Y.3
  • 46
    • 38449094307 scopus 로고    scopus 로고
    • Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F
    • R. E. Kuestner, D.W. Taft, A. Haran et al., "Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F, " The Journal of Immunology, vol. 179, no. 8, pp. 5462-5473, 2007.
    • (2007) The Journal of Immunology , vol.179 , Issue.8 , pp. 5462-5473
    • Kuestner, R.E.1    Taft, D.W.2    Haran, A.3
  • 47
    • 67649835097 scopus 로고    scopus 로고
    • Expression of interleukin-17RC protein in normal human tissues
    • article 19
    • D. Ge and Z. You, "Expression of interleukin-17RC protein in normal human tissues, " International Archives of Medicine, vol. 1, no. 1, article 19, 2008.
    • (2008) International Archives of Medicine , vol.1 , Issue.1
    • Ge, D.1    You, Z.2
  • 48
    • 59449105964 scopus 로고    scopus 로고
    • IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling
    • Z. Rong, A. Wang, Z. Li et al., "IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling, " Cell Research, vol. 19, no. 2, pp. 208-215, 2009.
    • (2009) Cell Research , vol.19 , Issue.2 , pp. 208-215
    • Rong, Z.1    Wang, A.2    Li, Z.3
  • 49
    • 33646358725 scopus 로고    scopus 로고
    • Identification and functional characterization of a novel interleukin 17 receptor: A possible mitogenic activation through ras/mitogenactivated protein kinase signaling pathway
    • T.-S. Li, X.-N. Li, Z.-J. Chang, X.-Y. Fu, and L. Liu, "Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras/mitogenactivated protein kinase signaling pathway, " Cellular Signalling, vol. 18, no. 8, pp. 1287-1298, 2006.
    • (2006) Cellular Signalling , vol.18 , Issue.8 , pp. 1287-1298
    • Li, T.-S.1    Li, X.-N.2    Chang, Z.-J.3    Fu, X.-Y.4    Liu, L.5
  • 51
    • 79953310900 scopus 로고    scopus 로고
    • Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes
    • A. Hot and P. Miossec, "Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes, " Annals of the Rheumatic Diseases, vol. 70, no. 5, pp. 727-732, 2011.
    • (2011) Annals of the Rheumatic Diseases , vol.70 , Issue.5 , pp. 727-732
    • Hot, A.1    Miossec, P.2
  • 52
    • 78649404973 scopus 로고    scopus 로고
    • Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling
    • S. Zhu, W. Pan, P. Shi et al., "Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling, " The Journal of Experimental Medicine, vol. 207, no. 12, pp. 2647-2662, 2010.
    • (2010) The Journal of Experimental Medicine , vol.207 , Issue.12 , pp. 2647-2662
    • Zhu, S.1    Pan, W.2    Shi, P.3
  • 53
    • 79955416252 scopus 로고    scopus 로고
    • Interleukin-17 contributes to the pathogenesis of autoimmune hepatitis through inducing hepatic interleukin-6 expression
    • Article ID e18909
    • L. Zhao, Y. Tang, Z. You et al., "Interleukin-17 contributes to the pathogenesis of autoimmune hepatitis through inducing hepatic interleukin-6 expression, " PLoS ONE, vol. 6, no. 4, Article ID e18909, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.4
    • Zhao, L.1    Tang, Y.2    You, Z.3
  • 55
    • 84896733113 scopus 로고    scopus 로고
    • Dysfunctional CD39 regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis
    • C. R. Grant, R. Liberal, B. S. Holder et al., "Dysfunctional CD39regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis, " Hepatology, vol. 59, no. 3, pp. 1007-1015, 2014.
    • (2014) Hepatology , vol.59 , Issue.3 , pp. 1007-1015
    • Grant, C.R.1    Liberal, R.2    Holder, B.S.3
  • 56
    • 84861594192 scopus 로고    scopus 로고
    • Inhibition of interleukin-17 promotes differentiation of CD25-cells into stable T regulatory cells in patients with autoimmune hepatitis
    • 1526.e6-1535.e6
    • M. S. Longhi, R. Liberal, B. Holder et al., "Inhibition of interleukin-17 promotes differentiation of CD25-cells into stable T regulatory cells in patients with autoimmune hepatitis, " Gastroenterology, vol. 142, no. 7, pp. 1526.e6-1535.e6, 2012.
    • (2012) Gastroenterology , vol.142 , Issue.7
    • Longhi, M.S.1    Liberal, R.2    Holder, B.3
  • 57
    • 77952711598 scopus 로고    scopus 로고
    • Diagnosis and management of autoimmune hepatitis
    • M. P. Manns, A. J. Czaja, J. D. Gorham et al., "Diagnosis and management of autoimmune hepatitis, " Hepatology, vol. 51, no. 6, pp. 2193-2213, 2010.
    • (2010) Hepatology , vol.51 , Issue.6 , pp. 2193-2213
    • Manns, M.P.1    Czaja, A.J.2    Gorham, J.D.3
  • 58
    • 84883558259 scopus 로고    scopus 로고
    • Increased IL-23 and IL-17 expression by peripheral blood cells of patients with primary biliary cirrhosis
    • C. Qian, T. Jiang, W. Zhang et al., "Increased IL-23 and IL-17 expression by peripheral blood cells of patients with primary biliary cirrhosis, " Cytokine, vol. 64, no. 1, pp. 172-180, 2013.
    • (2013) Cytokine , vol.64 , Issue.1 , pp. 172-180
    • Qian, C.1    Jiang, T.2    Zhang, W.3
  • 59
    • 58849115337 scopus 로고    scopus 로고
    • Hepatic IL-17 responses in human and murine primary biliary cirrhosis
    • R. Y. Z. Lan, T. L. Salunga, K. Tsuneyama et al., "Hepatic IL-17 responses in human and murine primary biliary cirrhosis, " Journal of Autoimmunity, vol. 32, no. 1, pp. 43-51, 2009.
    • (2009) Journal of Autoimmunity , vol.32 , Issue.1 , pp. 43-51
    • Lan, R.Y.Z.1    Salunga, T.L.2    Tsuneyama, K.3
  • 60
    • 67650668741 scopus 로고    scopus 로고
    • Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis
    • K. Harada, S. Shimoda, Y. Sato, K. Isse, H. Ikeda, and Y. Nakanuma, "Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis, " Clinical and Experimental Immunology, vol. 157, no. 2, pp. 261-270, 2009.
    • (2009) Clinical and Experimental Immunology , vol.157 , Issue.2 , pp. 261-270
    • Harada, K.1    Shimoda, S.2    Sato, Y.3    Isse, K.4    Ikeda, H.5    Nakanuma, Y.6
  • 61
    • 84899480316 scopus 로고    scopus 로고
    • IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy
    • C.-Y. Yang, X. Ma, K. Tsuneyama et al., "IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: implications for therapy, " Hepatology, vol. 59, no. 5, pp. 1944-1953, 2014.
    • (2014) Hepatology , vol.59 , Issue.5 , pp. 1944-1953
    • Yang, C.-Y.1    Ma, X.2    Tsuneyama, K.3
  • 62
    • 78650794235 scopus 로고    scopus 로고
    • Significance of periductal Langerhans cells and biliary epithelial cell-derived macrophage inflammatory protein-3 in the pathogenesis of primary biliary cirrhosis
    • K. Harada, S. Shimoda, H. Ikeda et al., "Significance of periductal Langerhans cells and biliary epithelial cell-derived macrophage inflammatory protein-3 in the pathogenesis of primary biliary cirrhosis, " Liver International, vol. 31, no. 2, pp. 245-253, 2011.
    • (2011) Liver International , vol.31 , Issue.2 , pp. 245-253
    • Harada, K.1    Shimoda, S.2    Ikeda, H.3
  • 63
    • 58949098337 scopus 로고    scopus 로고
    • Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2R -/-mice
    • W. Hsu, W. Zhang, K. Tsuneyama et al., "Differential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2R -/-mice, " Hepatology, vol. 49, no. 1, pp. 133-140, 2009.
    • (2009) Hepatology , vol.49 , Issue.1 , pp. 133-140
    • Hsu, W.1    Zhang, W.2    Tsuneyama, K.3
  • 64
    • 84883826611 scopus 로고    scopus 로고
    • Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis
    • Article ID e74225
    • K. Kawata, M. Tsuda, G.-X. Yang et al., "Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis, " PLoS ONE, vol. 8, no. 9, Article ID e74225, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Kawata, K.1    Tsuda, M.2    Yang, G.-X.3
  • 65
    • 84859939127 scopus 로고    scopus 로고
    • Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent
    • C.-Y. Yang, P. S. C. Leung, G.-X. Yang et al., "Epitope-specific anti-nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine-dependent, " Clinical and Experimental Immunology, vol. 168, no. 3, pp. 261-267, 2012.
    • (2012) Clinical and Experimental Immunology , vol.168 , Issue.3 , pp. 261-267
    • Yang, C.-Y.1    Leung, P.S.C.2    Yang, G.-X.3
  • 66
    • 84883229970 scopus 로고    scopus 로고
    • Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis
    • J. Katt, D. Schwinge, T. Schoknecht et al., "Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis, " Hepatology, vol. 58, no. 3, pp. 1084-1093, 2013.
    • (2013) Hepatology , vol.58 , Issue.3 , pp. 1084-1093
    • Katt, J.1    Schwinge, D.2    Schoknecht, T.3
  • 68
    • 84865461464 scopus 로고    scopus 로고
    • Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice
    • F. Meng, K. Wang, T. Aoyama et al., "Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice, " Gastroenterology, vol. 143, no. 3, pp. 765-776, 2012.
    • (2012) Gastroenterology , vol.143 , Issue.3 , pp. 765-776
    • Meng, F.1    Wang, K.2    Aoyama, T.3
  • 69
  • 70
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Y. Zheng, D. M. Danilenko, P. Valdez et al., "Interleukin-22, a T17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis, " Nature, vol. 445, no. 7128, pp. 648-651, 2007.
    • (2007) Nature , vol.445 , Issue.7128 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3
  • 71
    • 0842324613 scopus 로고    scopus 로고
    • Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice
    • A. Ogawa, A. and oh, Y. Araki, T. Bamba, and Y. Fujiyama, "Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice, " Clinical Immunology, vol. 110, no. 1, pp. 55-62, 2004.
    • (2004) Clinical Immunology , vol.110 , Issue.1 , pp. 55-62
    • Ogawa, A.1    Andoh, A.2    Araki, Y.3    Bambaand, T.4    Fujiyama, Y.5
  • 72
    • 1042267236 scopus 로고    scopus 로고
    • Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion
    • E. Lubberts, M. I. Koenders, B. Oppers-Walgreen et al., "Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion, " Arthritis and Rheumatism, vol. 50, no. 2, pp. 650-659, 2004.
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.2 , pp. 650-659
    • Lubberts, E.1    Koenders, M.I.2    Oppers-Walgreen, B.3
  • 73
    • 38349178776 scopus 로고    scopus 로고
    • Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
    • H.-C. Hsu, P. Yang, J. Wang et al., "Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice, " Nature Immunology, vol. 9, no. 2, pp. 166-175, 2008.
    • (2008) Nature Immunology , vol.9 , Issue.2 , pp. 166-175
    • Hsu, H.-C.1    Yang, P.2    Wang, J.3
  • 75
    • 67650750880 scopus 로고    scopus 로고
    • The liver as a lymphoid organ
    • I. N. Crispe, "The liver as a lymphoid organ, " Annual Review of Immunology, vol. 27, pp. 147-163, 2009.
    • (2009) Annual Review of Immunology , vol.27 , pp. 147-163
    • Crispe, I.N.1
  • 76
    • 33646052605 scopus 로고    scopus 로고
    • Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis
    • M. S. Longhi, M. J. Hussain, R. R. Mitry et al., "Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis, " The Journal of Immunology, vol. 176, no. 7, pp. 4484-4491, 2006.
    • (2006) The Journal of Immunology , vol.176 , Issue.7 , pp. 4484-4491
    • Longhi, M.S.1    Hussain, M.J.2    Mitry, R.R.3
  • 77
    • 77956643943 scopus 로고    scopus 로고
    • A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis
    • S. Ferri, M. S. Longhi, C. de Molo et al., "A multifaceted imbalance of T cells with regulatory function characterizes type 1 autoimmune hepatitis, " Hepatology, vol. 52, no. 3, pp.999-1007, 2010.
    • (2010) Hepatology , vol.52 , Issue.3 , pp. 999-1007
    • Ferri, S.1    Longhi, M.S.2    De Molo, C.3
  • 78
    • 0021997185 scopus 로고
    • Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-Tolerance; Deficit of a T cell subset as a possible cause of autoimmune disease
    • S. Sakaguchi, K. Fukuma, K. Kuribayashi, and T. Masuda, "Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-Tolerance; deficit of a T cell subset as a possible cause of autoimmune disease, " The Journal of Experimental Medicine, vol. 161, no. 1, pp. 72-87, 1985.
    • (1985) The Journal of Experimental Medicine , vol.161 , Issue.1 , pp. 72-87
    • Sakaguchi, S.1    Fukuma, K.2    Kuribayashi, K.3    Masuda, T.4
  • 79
    • 73349127157 scopus 로고    scopus 로고
    • CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis
    • J. M. Fletcher, R. Lonergan, L. Costelloe et al., "CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis, " Journal of Immunology, vol. 183, no. 11, pp. 7602-7610, 2009.
    • (2009) Journal of Immunology , vol.183 , Issue.11 , pp. 7602-7610
    • Fletcher, J.M.1    Lonergan, R.2    Costelloe, L.3
  • 80
    • 39549122228 scopus 로고    scopus 로고
    • Expansion and de novo generation of potentially therapeutic regulatory T cells in patients with autoimmune hepatitis
    • M. S. Longhi, F. Meda, P. Wang et al., "Expansion and de novo generation of potentially therapeutic regulatory T cells in patients with autoimmune hepatitis, " Hepatology, vol. 47, no. 2, pp. 581-591, 2008.
    • (2008) Hepatology , vol.47 , Issue.2 , pp. 581-591
    • Longhi, M.S.1    Meda, F.2    Wang, P.3
  • 84
    • 0024334615 scopus 로고
    • Antigen presenting cells in liver biopsies from patients with primary biliary cirrhosis
    • G. Ballardini, M. Fallani, F. B. Bianchi, and E. Pisi, "Antigen presenting cells in liver biopsies from patients with primary biliary cirrhosis, " Autoimmunity, vol. 3, no. 2, pp. 135-144, 1989.
    • (1989) Autoimmunity , vol.3 , Issue.2 , pp. 135-144
    • Ballardini, G.1    Fallani, M.2    Bianchi, F.B.3    Pisi, E.4
  • 85
    • 33746210257 scopus 로고    scopus 로고
    • Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-receptor II dominant-negative mice
    • S. Oertelt, Z.-X. Lian, C.-M. Cheng et al., "Anti-mitochondrial antibodies and primary biliary cirrhosis in TGF-receptor II dominant-negative mice, " The Journal of Immunology, vol. 177, no. 3, pp. 1655-1660, 2006.
    • (2006) The Journal of Immunology , vol.177 , Issue.3 , pp. 1655-1660
    • Oertelt, S.1    Lian, Z.-X.2    Cheng, C.-M.3
  • 86
    • 33846449067 scopus 로고    scopus 로고
    • Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis
    • M. Nakamura, H. Kondo, T. Mori et al., "Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis, " Hepatology, vol. 45, no. 1, pp. 118-127, 2007.
    • (2007) Hepatology , vol.45 , Issue.1 , pp. 118-127
    • Nakamura, M.1    Kondo, H.2    Mori, T.3
  • 87
    • 0031946553 scopus 로고    scopus 로고
    • Autoantibodies against a 210 kDa glycoprotein of the nuclear pore complex as a prognostic marker in patients with primary biliary cirrhosis
    • S. Itoh, T. Ichida, T. Yoshida et al., "Autoantibodies against a 210 kDa glycoprotein of the nuclear pore complex as a prognostic marker in patients with primary biliary cirrhosis, " Journal of Gastroenterology and Hepatology, vol. 13, no. 3, pp. 257-265, 1998.
    • (1998) Journal of Gastroenterology and Hepatology , vol.13 , Issue.3 , pp. 257-265
    • Itoh, S.1    Ichida, T.2    Yoshida, T.3
  • 89
    • 0033002048 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis
    • P. Angulo and K. D. Lindor, "Primary sclerosing cholangitis, " Hepatology, vol. 30, no. 1, pp. 325-332, 1999.
    • (1999) Hepatology , vol.30 , Issue.1 , pp. 325-332
    • Angulo, P.1    Lindor, K.D.2
  • 90
    • 84883150093 scopus 로고    scopus 로고
    • Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management
    • J. E. Eaton, J. A. Talwalkar, K. N. Lazaridis, G. J. Gores, and K. D. Lindor, "Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management, " Gastroenterology, vol. 145, no. 3, pp. 521-536, 2013.
    • (2013) Gastroenterology , vol.145 , Issue.3 , pp. 521-536
    • Eaton, J.E.1    Talwalkar, J.A.2    Lazaridis, K.N.3    Gores, G.J.4    Lindor, K.D.5
  • 92
    • 67349123124 scopus 로고    scopus 로고
    • Influence of dominant bile duct stenoses and biliary infections on outcome in primary sclerosing cholangitis
    • G. Rudolph, D. Gotthardt, P. Kloters-Plachky, H. Kulaksiz, D. Rost, and A. Stiehl, "Influence of dominant bile duct stenoses and biliary infections on outcome in primary sclerosing cholangitis, " Journal of Hepatology, vol. 51, no. 1, pp. 149-155, 2009.
    • (2009) Journal of Hepatology , vol.51 , Issue.1 , pp. 149-155
    • Rudolph, G.1    Gotthardt, D.2    Kloters-Plachky, P.3    Kulaksiz, H.4    Rost, D.5    Stiehl, A.6
  • 93
    • 0036788262 scopus 로고    scopus 로고
    • Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles
    • P. Fickert, G. Zollner, A. Fuchsbichler et al., "Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles, " Gastroenterology, vol. 123, no. 4, pp. 1238-1251, 2002.
    • (2002) Gastroenterology , vol.123 , Issue.4 , pp. 1238-1251
    • Fickert, P.1    Zollner, G.2    Fuchsbichler, A.3
  • 95
    • 79951512605 scopus 로고    scopus 로고
    • Integrative responses to IL-17 and TNF-in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis
    • A. Chiricozzi, E. Guttman-Yassky, M. Suárez-Farias et al., "Integrative responses to IL-17 and TNF-in human keratinocytes account for key inflammatory pathogenic circuits in psoriasis, " Journal of Investigative Dermatology, vol. 131, no. 3, pp. 677-687, 2011.
    • (2011) Journal of Investigative Dermatology , vol.131 , Issue.3 , pp. 677-687
    • Chiricozzi, A.1    Guttman-Yassky, E.2    Suárez-Farias, M.3
  • 96
    • 0037216498 scopus 로고    scopus 로고
    • Increased expression of interleukin 17 in inflammatory bowel disease
    • S. Fujino, A. and oh, S. Bamba et al., "Increased expression of interleukin 17 in inflammatory bowel disease, " Gut, vol. 52, no. 1, pp. 65-70, 2003.
    • (2003) Gut , vol.52 , Issue.1 , pp. 65-70
    • Fujino, S.1    Andoh, A.2    Bamba, S.3
  • 97
    • 0033134608 scopus 로고    scopus 로고
    • IL-17 in synovial fluids frompatients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
    • S. Kotake, N. Udagawa, N. Takahashi et al., "IL-17 in synovial fluids frompatients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis, "The Journal of Clinical Investigation, vol. 103, no. 9, pp. 1345-1352, 1999.
    • (1999) The Journal of Clinical Investigation , vol.103 , Issue.9 , pp. 1345-1352
    • Kotake, S.1    Udagawa, N.2    Takahashi, N.3
  • 98
    • 0038281377 scopus 로고    scopus 로고
    • IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients
    • G. Dong, R. Ye, W. Shi et al., "IL-17 induces autoantibody overproduction and peripheral blood mononuclear cell overexpression of IL-6 in lupus nephritis patients, " Chinese Medical Journal, vol. 116, no. 4, pp. 543-548, 2003.
    • (2003) Chinese Medical Journal , vol.116 , Issue.4 , pp. 543-548
    • Dong, G.1    Ye, R.2    Shi, W.3
  • 99
    • 84860238945 scopus 로고    scopus 로고
    • IL-17/IL-17 receptor system in autoimmune disease: Mechanisms and therapeutic potential
    • S. Zhu and Y. Qian, "IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential, " Clinical Science, vol. 122, no. 11, pp. 487-511, 2012.
    • (2012) Clinical Science , vol.122 , Issue.11 , pp. 487-511
    • Zhu, S.1    Qian, Y.2
  • 100
    • 84873124241 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in the treatment of moderate-Tosevere plaque psoriasis: A r and omized, double-blind, placebocontrolled phase II dose-ranging study
    • K. A. Papp, R. G. Langley, B. Sigurgeirsson et al., "Efficacy and safety of secukinumab in the treatment of moderate-Tosevere plaque psoriasis: a r and omized, double-blind, placebocontrolled phase II dose-ranging study, " British Journal of Dermatology, vol. 168, no. 2, pp. 412-421, 2013.
    • (2013) British Journal of Dermatology , vol.168 , Issue.2 , pp. 412-421
    • Papp, K.A.1    Langley, R.G.2    Sigurgeirsson, B.3
  • 101
    • 84859073115 scopus 로고    scopus 로고
    • Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis
    • C. Leonardi, R. Matheson, C. Zachariae et al., "Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis, " The New Engl and Journal of Medicine, vol. 366, no. 13, pp. 1190-1191, 2012.
    • (2012) The New Engl and Journal of Medicine , vol.366 , Issue.13 , pp. 1190-1191
    • Leonardi, C.1    Matheson, R.2    Zachariae, C.3
  • 102
    • 84859017988 scopus 로고    scopus 로고
    • Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis
    • K. A. Papp, C. Leonardi, A. Menter et al., "Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis, " The New Engl and Journal ofMedicine, vol. 366, no. 13, pp. 1181-1189, 2012.
    • (2012) The New Engl and Journal OfMedicine , vol.366 , Issue.13 , pp. 1181-1189
    • Papp, K.A.1    Leonardi, C.2    Menter, A.3
  • 103
    • 84887076617 scopus 로고    scopus 로고
    • IL-17 antibodies gain momentum
    • M. T. Tse, "IL-17 antibodies gain momentum, " Nature Reviews Drug Discovery, vol. 12, no. 11, pp. 815-816, 2013.
    • (2013) Nature Reviews Drug Discovery , vol.12 , Issue.11 , pp. 815-816
    • Tse, M.T.1
  • 104
    • 84877603562 scopus 로고    scopus 로고
    • Efficacy and safety of secukinumab in patients with rheumatoid arthritis: A phase II, dose-finding, double-blind, r and omised, placebo controlled study
    • M. C. Genovese, P. Durez, H. B. Richards et al., "Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, r and omised, placebo controlled study, " Annals of the Rheumatic Diseases, vol. 72, no. 6, pp. 863-869, 2013.
    • (2013) Annals of the Rheumatic Diseases , vol.72 , Issue.6 , pp. 863-869
    • Genovese, M.C.1    Durez, P.2    Richards, H.B.3
  • 105
    • 84887992906 scopus 로고    scopus 로고
    • Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: Arandomised, double-blind, placebo-controlled trial
    • D. Baeten, X. Baraliakos, J. Braun et al., "Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: arandomised, double-blind, placebo-controlled trial, " The Lancet, vol. 382, pp. 1705-1713, 2013.
    • (2013) The Lancet , vol.382 , pp. 1705-1713
    • Baeten, D.1    Baraliakos, X.2    Braun, J.3
  • 106
    • 84875697084 scopus 로고    scopus 로고
    • Secukinumab in the treatment of noninfectious uveitis: Results of three randomized, controlled clinical trials
    • A.D. Dick, I. Tugal-Tutkun, S. Foster et al., "Secukinumab in the treatment of noninfectious uveitis: results of three randomized, controlled clinical trials, " Ophthalmology, vol. 120, no. 4, pp. 777-787, 2013.
    • (2013) Ophthalmology , vol.120 , Issue.4 , pp. 777-787
    • Dick, A.D.1    Tugal-Tutkun, I.2    Foster, S.3
  • 107
    • 84903478179 scopus 로고    scopus 로고
    • A phase II randomized study of subcutaneous ixekizumab, an antiinterleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors
    • M. C. Genovese, M. Greenwald, C. S. Cho et al., "A phase II randomized study of subcutaneous ixekizumab, an antiinterleukin-17 monoclonal antibody, in rheumatoid arthritis patients who were naive to biologic agents or had an inadequate response to tumor necrosis factor inhibitors, " Arthritis & Rheumatism, vol. 66, no. 7, pp. 1693-1704, 2014.
    • (2014) Arthritis & Rheumatism , vol.66 , Issue.7 , pp. 1693-1704
    • Genovese, M.C.1    Greenwald, M.2    Cho, C.S.3
  • 108
    • 84868680312 scopus 로고    scopus 로고
    • Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohns disease: Unexpected results of arandomised, double-blindplacebo-controlled trial
    • W. Hueber, B. E. Sands, S. Lewitzky et al., "Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohns disease: Unexpected results of arandomised, double-blindplacebo-controlled trial, " Gut, vol. 61, no. 12, pp. 1693-1700, 2012.
    • (2012) Gut , vol.61 , Issue.12 , pp. 1693-1700
    • Hueber, W.1    Sands, B.E.2    Lewitzky, S.3
  • 109
    • 33745297345 scopus 로고    scopus 로고
    • Cutting edge: Interleukin 17 signals through a heteromeric receptor complex
    • D. Toy, D. Kugler, M. Wolfson et al., "Cutting edge: interleukin 17 signals through a heteromeric receptor complex, " Journal of Immunology, vol. 177, no. 1, pp. 36-39, 2006.
    • (2006) Journal of Immunology , vol.177 , Issue.1 , pp. 36-39
    • Toy, D.1    Kugler, D.2    Wolfson, M.3
  • 110
    • 40449113569 scopus 로고    scopus 로고
    • IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood
    • S. Zrioual, M.-L. Toh, A. Tournadre et al., "IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood, " Journal of Immunology, vol. 180, no. 1, pp. 655-663, 2008.
    • (2008) Journal of Immunology , vol.180 , Issue.1 , pp. 655-663
    • Zrioual, S.1    Toh, M.-L.2    Tournadre, A.3
  • 112
    • 84899991797 scopus 로고    scopus 로고
    • Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional nonbiological and biological anti-Tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, doubleblind, placebo-controlled
    • C. Ritchlin, P. Rahman, A. Kavanaugh et al., "Efficacy and safety of the anti-IL-12/23 p40 monoclonal antibody, ustekinumab, in patients with active psoriatic arthritis despite conventional nonbiological and biological anti-Tumour necrosis factor therapy: 6-month and 1-year results of the phase 3, multicentre, doubleblind, placebo-controlled, " Annals of the Rheumatic Diseases, vol. 73, no. 6, pp. 990-999, 2014.
    • (2014) Annals of the Rheumatic Diseases , vol.73 , Issue.6 , pp. 990-999
    • Ritchlin, C.1    Rahman, P.2    Kavanaugh, A.3
  • 113
    • 84871701834 scopus 로고    scopus 로고
    • Ustekinumab induction and maintenance therapy in refractory Crohns disease
    • W. J. S and born, C. Gasink, L.-L. Gao et al., "Ustekinumab induction and maintenance therapy in refractory Crohns disease, " The New Engl and Journal of Medicine, vol. 367, no. 16, pp. 1519-1528, 2012.
    • (2012) The New Engl and Journal of Medicine , vol.367 , Issue.16 , pp. 1519-1528
    • Sandborn, W.J.1    Gasink, C.2    Gao, L.-L.3
  • 114
    • 74249094930 scopus 로고    scopus 로고
    • Comparison of ustekinumab and etanercept for moderate-Tosevere psoriasis
    • C. E. M. Griffiths, B. E. Strober, P. van de Kerkhof et al., "Comparison of ustekinumab and etanercept for moderate-Tosevere psoriasis, "The New Engl and Journal ofMedicine, vol. 362, no. 2, pp. 118-128, 2010.
    • (2010) The New Engl and Journal OfMedicine , vol.362 , Issue.2 , pp. 118-128
    • Griffiths, C.E.M.1    Strober, B.E.2    Kerkhof De P.Van3
  • 115
    • 84875433817 scopus 로고    scopus 로고
    • Long-Term safety of ustekinumab in patients with moderate-To-severe psoriasis: Final results from 5 years of follow-up
    • K. A. Papp, C. E. M. Griffiths, K. Gordon et al., "Long-Term safety of ustekinumab in patients with moderate-To-severe psoriasis: final results from 5 years of follow-up, " British Journal of Dermatology, vol. 168, no. 4, pp. 844-854, 2013.
    • (2013) British Journal of Dermatology , vol.168 , Issue.4 , pp. 844-854
    • Papp, K.A.1    Griffiths, C.E.M.2    Gordon, K.3
  • 116
    • 84866934694 scopus 로고    scopus 로고
    • Targeting IL-17 and T17 cells in chronic inflammation
    • P. Miossec and J. K. Kolls, "Targeting IL-17 and T17 cells in chronic inflammation, " Nature Reviews Drug Discovery, vol. 11, no. 10, pp. 763-776, 2012.
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.10 , pp. 763-776
    • Miossec, P.1    Kolls, J.K.2
  • 117
    • 84897481839 scopus 로고    scopus 로고
    • Tocilizumab in the treatment of rheumatoid arthritis and beyond
    • A. Shetty, R. Hanson, P. Korsten et al., "Tocilizumab in the treatment of rheumatoid arthritis and beyond, " Drug Design, Development and Therapy, vol. 8, pp. 349-364, 2014.
    • (2014) Drug Design, Development and Therapy , vol.8 , pp. 349-364
    • Shetty, A.1    Hanson, R.2    Korsten, P.3
  • 118
    • 84890501711 scopus 로고    scopus 로고
    • Tocilizumab: A reviewof its use in the treatment of juvenile idiopathic arthritis
    • J. E. Frampton, "Tocilizumab: a reviewof its use in the treatment of juvenile idiopathic arthritis, " PediatricDrugs, vol. 15, no. 6, pp. 515-531, 2013.
    • (2013) PediatricDrugs , vol.15 , Issue.6 , pp. 515-531
    • Frampton, J.E.1
  • 119
    • 77950258225 scopus 로고    scopus 로고
    • Actual status of antiinterleukin-1 therapies in rheumatic diseases
    • M. Geyer and U. Müller-Ladner, "Actual status of antiinterleukin-1 therapies in rheumatic diseases, " Current Opinion in Rheumatology, vol. 22, no. 3, pp. 246-251, 2010.
    • (2010) Current Opinion in Rheumatology , vol.22 , Issue.3 , pp. 246-251
    • Geyer, M.1    Müller-Ladner, U.2
  • 120
    • 84872281985 scopus 로고    scopus 로고
    • Identification of potent and selective diphenylpropanamide RORinhibitors
    • J. R. Huh, E. E. Englund, H. Wang et al., "Identification of potent and selective diphenylpropanamide RORinhibitors, " ACS Medicinal Chemistry Letters, vol. 4, no. 1, pp. 79-84, 2013.
    • (2013) ACS Medicinal Chemistry Letters , vol.4 , Issue.1 , pp. 79-84
    • Huh, J.R.1    Englund, E.E.2    Wang, H.3
  • 122
    • 84891501796 scopus 로고    scopus 로고
    • Flurry of deal-making surrounds new autoimmunity target
    • article 1078
    • S. C. P. Williams, "Flurry of deal-making surrounds new autoimmunity target, " Nature Medicine, vol. 19, no. 9, article 1078, 2013.
    • (2013) Nature Medicine , vol.19 , Issue.9
    • Williams, S.C.P.1
  • 123
    • 79955526989 scopus 로고    scopus 로고
    • Suppression of TH17 differentiation and autoimmunity by a synthetic ROR lig and
    • L. A. Solt, N. Kumar, P. Nuhant et al., "Suppression of TH17 differentiation and autoimmunity by a synthetic ROR lig and , " Nature, vol. 472, no. 7344, pp. 491-494, 2011.
    • (2011) Nature , vol.472 , Issue.7344 , pp. 491-494
    • Solt, L.A.1    Kumar, N.2    Nuhant, P.3
  • 124
    • 0037144514 scopus 로고    scopus 로고
    • Identification of Reverb as a novel ROR target gene
    • P. Delerive, W. W. Chin, and C. S. Suen, "Identification of Reverb as a novel ROR target gene, " Journal of Biological Chemistry, vol. 277, no. 38, pp. 35013-35018, 2002.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.38 , pp. 35013-35018
    • Delerive, P.1    Chin, W.W.2    Suen, C.S.3
  • 125
    • 33845918194 scopus 로고    scopus 로고
    • The orphan nuclear receptor Rev-erb regulates circadian expression of plasminogen activator inhibitor type 1
    • J. Wang, L. Yin, and M. A. Lazar, "The orphan nuclear receptor Rev-erb regulates circadian expression of plasminogen activator inhibitor type 1, "The Journal of Biological Chemistry, vol. 281, no. 45, pp. 33842-33848, 2006.
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.45 , pp. 33842-33848
    • Wang, J.1    Yin, L.2    Lazar, M.A.3
  • 126
    • 40849086444 scopus 로고    scopus 로고
    • Identification of oxysterol 7-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor (ROR) (NR1F1) target gene and a functional cross-Talk between ROR and liver X receptor (NR1H3)
    • T. Wada, S. K. Hong, M. Angers et al., "Identification of oxysterol 7-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor (ROR) (NR1F1) target gene and a functional cross-Talk between ROR and liver X receptor (NR1H3), " Molecular Pharmacology, vol. 73, no. 3, pp. 891-899, 2008.
    • (2008) Molecular Pharmacology , vol.73 , Issue.3 , pp. 891-899
    • Wada, T.1    Hong, S.K.2    Angers, M.3
  • 127
    • 84860176210 scopus 로고    scopus 로고
    • Identification of SR2211: A potent synthetic ROR-selective modulator
    • N. Kumar, B. Lyda, M. R. Chang et al., "Identification of SR2211: a potent synthetic ROR-selective modulator, " ACS Chemical Biology, vol. 7, no. 4, pp. 672-677, 2012.
    • (2012) ACS Chemical Biology , vol.7 , Issue.4 , pp. 672-677
    • Kumar, N.1    Lyda, B.2    Chang, M.R.3
  • 128
    • 78049343768 scopus 로고    scopus 로고
    • Genome-wide asociation study identifies a psoriasis susceptibility locus at TRAF3IP2
    • E. ELinghaus, D. ELinghaus, P. E. Stuart et al., "Genome-wide asociation study identifies a psoriasis susceptibility locus at TRAF3IP2, " Nature Genetics, vol. 42, no. 11, pp. 991-995, 2010.
    • (2010) Nature Genetics , vol.42 , Issue.11 , pp. 991-995
    • Elinghaus, E.1    Elinghaus, D.2    Stuart, P.E.3
  • 129
    • 78049350350 scopus 로고    scopus 로고
    • CoMon variants at TRAF3IP2 are aSociated with susceptibility to psoriatic arthritis and psoriasis
    • U. Hüffmeier, S. Uebe, A. B. Ekici et al., "CoMon variants at TRAF3IP2 are aSociated with susceptibility to psoriatic arthritis and psoriasis, "NatureGenetics, vol. 42, no. 11, pp. 996-999, 2010.
    • (2010) NatureGenetics , vol.42 , Issue.11 , pp. 996-999
    • Hüffmeier, U.1    Uebe, S.2    Ekici, A.B.3
  • 130
    • 80455176377 scopus 로고    scopus 로고
    • A CC loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17-And IL-25-induced inflammation
    • article ra72
    • C. Liu, S. Swaidani, W. Qian et al., "A CC loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17-And IL-25-induced inflammation, " Science Signaling, vol. 4, no. 197, article ra72, 2011.
    • (2011) Science Signaling , vol.4 , Issue.197
    • Liu, C.1    Swaidani, S.2    Qian, W.3
  • 131
    • 38949194566 scopus 로고    scopus 로고
    • Structure-function relationships in the IL-17 receptor: Implications for signal transduction and therapy
    • F. Shen and S. L. Gaffen, "Structure-function relationships in the IL-17 receptor: implications for signal transduction and therapy, " Cytokine, vol. 41, no. 2, pp. 92-104, 2008.
    • (2008) Cytokine , vol.41 , Issue.2 , pp. 92-104
    • Shen, F.1    Gaffen, S.L.2


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