Identification of SR2211: A potent synthetic RORγ-selective modulator

ACS Chemical Biology

Volumn 7, Issue 4, 2012, Pages 672-677

  Kumar, Naresh ^a   Lyda, Brent ^a   Chang, Mi Ra ^a   Lauer, Janelle L ^a   Solt, Laura A ^a   Burris, Thomas P ^a   Kamenecka, Theodore M ^a   Griffin, Patrick R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

[1,1,1,3,3,3 HEXAFLUORO 2 [2 FLUORO 4' [[4 (PYRIDIN 4 YLMETHYL)PIPERAZIN 1 YL]METHYL] (1,1' BIPHENYL) 4 YL]PROPAN 2 OL]; IMMUNOMODULATING AGENT; INTERLEUKIN 17; RETINOIC ACID RECEPTOR GAMMA; RETINOIC ACID RECEPTOR RELATED ORPHAN RECEPTOR GAMMA; SR 2211; UNCLASSIFIED DRUG;

CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG PENETRATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; TH17 CELL;

ANIMALS; AUTOIMMUNE DISEASES; INTERLEUKIN-17; LIGANDS; MICE; PIPERAZINES; PROPANOLS; RECEPTORS, RETINOIC ACID; TH17 CELLS;

EID: 84860176210     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb200496y     Document Type: Review

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