Mechanism of interleukin-25 (IL-17E)-induced pulmonary inflammation and airways hyper-reactivity

Clinical and Experimental Allergy

Volumn 36, Issue 12, 2006, Pages 1575-1583

  Sharkhuu, T ^a   Matthaei, K I ^a   Forbes, E ^a   Mahalingam, S ^b   Hogan, S P ^c   Hansbro, P M ^d   Foster, P S ^a,d,e  

^a Biology and Environment   (Australia)

^b UNIVERSITY OF CANBERRA   (Australia)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF NEWCASTLE   (Australia)

^e HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Allergy asthma; Inflammation; Interleukins; Mouse model

Indexed keywords

ARGININOSUCCINATE SYNTHASE; CYTOKINE; EOTAXIN; INTERLEUKIN 25;

ALLERGIC DISEASE; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; HISTOPATHOLOGY; LUNG LAVAGE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; TH2 CELL;

ANIMALS; ARGINASE; ASTHMA; BIOLOGICAL MARKERS; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; CELLS, CULTURED; CHEMOKINES, CC; CYTOKINES; INTERLEUKIN-13; INTERLEUKIN-17; INTERLEUKIN-4; LUNG; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MUCUS; PNEUMONIA; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT6 TRANSCRIPTION FACTOR; TH2 CELLS;

EID: 33845460525     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02595.x     Document Type: Article

References (29)

1. Moseley TA, Haudenschild DR, Rose L, Reddi AH. Interleukin-17 family and IL-17 receptors. Cytokine Growth Factor Rev 2003; 14:155-74.
2. Aggarwal S, Gurney AL. IL-17: prototype member of an emerging cytokine family. J Leukoc Biol 2002; 71:1-8.
3. Hurst SD, Muchamuel T, Gorman DM et al. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J Immunol 2002; 169:443-53.
4. Fossiez F, Banchereau J, Murray R, Van Kooten C, Garrone P, Lebecque S. Interleukin-17. Int Rev Immunol 1998; 16:541-51.
5. Chabaud M, Fossiez F, Taupin JL et al. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines. J Immunol 1998; 161:409-14.
6. Li H, Chen J, Huang A et al. Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family. Proc Natl Acad Sci USA 2000; 97:773-8.
7. Starnes T, Broxmeyer HE, Robertson MJ, Hromas R. Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis. J Immunol 2002; 169:642-6.
8. Fort MM, Cheung J, Yen D et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001; 15:985-95.
9. Lee J, Ho WH, Maruoka M et al. IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1. J Biol Chem 2001; 276:1660-4.
10. Kim MR, Manoukian R, Yeh R et al. Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood 2002; 100:2330-40.
11. Gratchev A, Kzhyshkowska J, Duperrier K, Utikal J, Velten FW, Goerdt S. The receptor for interleukin-17E is induced by Th2 cytokines in antigen-presenting cells. Scand J Immunol 2004; 60:233-7.
12. Al-Tamemi S, Letuve S, Hajoui O et al. Th2 dependent induction of IL-25 receptors on human B-cells. J Allergy Clin Immunol 2005; 115:892.
13. Ikeda K, Nakajima H, Suzuki K et al. Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activation. Blood 2003; 101:3594-6.
14. Pan G, French D, Mao W et al. Forced expression of murine IL-17E induces growth retardation, jaundice, a Th2-biased response, and multiorgan inflammation in mice. J Immunol 2001; 167:6559-67.
15. + T cell IL-4 production is revealed in IL-4 receptor-deficient mice. Proc Natl Acad Sci USA 1997; 94:10838.
16. McKenzie GJ, Emson CL, Bell SE et al. Impaired development of Th2 cells in IL-13-deficient mice. Immunity 1998; 9:423-32.
17. Takeda K, Tanaka T, Shi W et al. Essential role of Stat6 in IL-4 signalling. Nature 1996; 380:627-30.
18. Mattes J, Yang M, Mahalingham S et al. Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma. J Exp Med 2002; 195:1433-44.
19. Hamelmann E, Schwarze J, Takeda K et al. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 1997; 156:766-75.
20. Yang M, Hogan SP, Henry PJ et al. Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin. Am J Respir Cell Mol Biol 2001; 25:522-30.
21. Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest 1997; 99:1329-39.
22. Webb DC, Mahalingam S, Cai Y, Matthaei KI, Donaldson DD, Foster PS. Antigen-specific production of interleukin (IL)-13 and IL-5 cooperate to mediate IL-4Ralpha-independent airway hyperreactivity. Eur J Immunol 2003; 33:3377-85.
23. Mahalingam S, Karupiah G, Takeda K, Akira S, Matthaei KI, Foster PS. Enhanced resistance in STAT6-deficient mice to infection with ectromelia virus. Proc Natl Acad Sci USA 2001; 98:6812-7.
24. Zimmermann N, King NE, Laporte J et al. Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest 2003; 111:1863-74.
25. Mould AW, Matthaei KI, Young IG, Foster PS. Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice. J Clin Invest 1997; 99:1064-71.
26. Modolell M, Corraliza IM, Link F, Soler G, Eichmann K. Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow-derived macrophages by TH1 and TH2 cytokines. Eur J Immunol 1995; 25:1101-4.
27. Munder MK, Eichmann K, Modolell M. Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotypes. J Immunol 1998; 160:5347-54.
28. Rutschman R, Lang R, Hesse M, Ihle JN, Wynn TA, Murray PJ. Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production. J Immunol 2001; 166:2173-7.
29. Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest 1997; 99:1329-39.