A pathogenic role of IL- 17 at the early stage of corneal allograft rejection

Transplant Immunology

Volumn 21, Issue 3, 2009, Pages 155-161

  Chen, Haiyong ^a   Wang, Weilin ^a   Xie, Haiyang ^a   Xu, Xiao ^a   Wu, Jian ^a   Jiang, Zhijun ^a   Zhang, Mangli ^a   Zhou, Lin ^a   Zheng, Shusen ^a  

^a BEIJING HOSPITAL   (China)

Author keywords

Allograft rejection; Cornea transplantation; Th1 cell; Th17 cell

Indexed keywords

CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; BAGG ALBINO MOUSE; CERVICAL LYMPH NODE; CONTROLLED STUDY; CORNEA TRANSPLANTATION; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE MODEL; DONOR; FLOW CYTOMETRY; GRAFT RECIPIENT; GRAFT REJECTION; GRAFT SURVIVAL; HELPER CELL; KERATOPLASTY; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE; SURVIVAL TIME; T LYMPHOCYTE; TH17 CELL; UPREGULATION;

ANIMALS; CORNEA; CORNEAL TRANSPLANTATION; CYTOKINES; GRAFT REJECTION; INTERLEUKIN-17; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

EID: 67349242957     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trim.2009.03.006     Document Type: Article

References (42)

1. Weaver C.T., Harrington L.E., Mangan P.R., Gavrieli M., and Murphy K.M. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24 (2006) 677-688
2. Reiner S.L. Development in motion: helper T cells at work. Cell 129 (2007) 33-36
3. Mangan P.R., Harrington L.E., O'Quinn D.B., Helms W.S., Bullard D.C., Elson C.O., et al. Transforming growth factor-β induces development of the Th17 lineage. Nature 441 (2006) 231-234
4. Zhou L., Ivanov I.I., Spolski R., Min R., Shenderov K., Egawa T., et al. IL-6 programs T(H)- 17 cell differentiation by promoting sequential engagement of the IL- 21 and IL- 23 pathways. Nat Immunol 8 9 (2007) 967-974
5. Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., et al. The orphan nuclear receptor RORγt directs the differentiation program of proinflammatory IL- 17+ T helper cells. Cell 126 (2006) 1121-1133
6. Veldhoen M., Hocking R.J., Atkins C.J., Locksley R.M., and Stockinger B. TGF- β in the context of an inflammatory cytokine milieu supports de novo differentiation of IL- 17- producing T cells. Immunity 24 (2006) 179-189
7. Aggarwal S., Ghilardi N., Xie M.H., de Sauvage F.J., and Gurney A.L. Interleukin- 23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin- 17. J Biol Chem 278 (2003) 1910-1914
8. Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
9. + regulatory T cells for immunologic self- tolerance and negative control of immune responses. Annu Rev Immunol 22 (2004) 531-562
10. Ye P., Garvey P.B., Zhang P., Nelson S., Bagby G., Summer W.R., et al. Interleukin- 17 and lung host defense against Klebsiella pneumoniae infection. Am J Respir Cell Mol Biol 25 (2001) 335-340
11. Infante- Duarte C., Horton H.F., Byrne M.C., and Kamradt T. Microbial lipopeptides induce the production of IL- 17 in Th cells. J Immunol 165 (2000) 6107-6115
12. Huang W., Na L., Fidel P.L., and Schwarzenberger P. Requirement of interleukin- 17A for systemic anti- Candida albicans host defense in mice. J Infect Dis 190 (2004) 624-631
13. Fujimoto M., Serada S., Mihara M., Uchiyama Y., Yoshida H., Koike N., et al. Interleukin- 6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses. Arthritis Rheum 58 (2008) 3710-3719
14. Cua D.J., Sherlock J., Chen Y., Murphy C.A., Joyce B., Seymour B., et al. Interleukin- 23 rather than interleukin- 12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421 (2003) 744-748
15. Jain R., Tartar D.M., Gregg R.K., Divekar R.D., Bell J.J., Lee H.H., et al. Innocuous IFN- γ induced by adjuvant- free antigen restores normoglycemia in NOD mice through inhibition of IL- 17 production. J Exp Med 205 (2008) 207-218
16. Antonysamy M.A., Fanslow W.C., Fu F., Li W., Qian S., Troutt A.B., et al. Evidence for a role of IL- 17 in organ allograft rejection: IL- 17 promotes the functional differentiation of dendritic cell progenitors. J Immunol 162 (1999) 577-584
17. Vanaudenaerde B.M., Dupont L.J., Wuyts W.A., Verbeken E.K., Meyts I., Bullens D.M., et al. The role of interleukin- 17 during acute rejection after lung transplantation. Eur Respir J 27 (2006) 779-787
18. Burlingham W.J., Love R.B., Jankowska-Gan E., Haynes L.D., Xu Q., Bobadilla J.L., et al. IL- 17- mediated cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. J Clin Invest 117 (2007) 3498-3506
19. Yuan X., Paez- Cortez J., Schmitt- Knosalla I., D'Addio F., Mfarrej B., Donnarumma M., et al. A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy. J Exp Med 22 (2008) 3133-3144
20. Burrell B.E., Csencsits K., Lu G., Grabauskiene S., and Bishop D.K. CD8+ Th17 mediate costimulation blockade- resistant allograft rejection in T- bet- deficient mice. J Immunol 181 (2008) 3906-3914
21. Carlson M.J., West M.L., Coghill J.M., Panoskaltsis- Mortari A., Blazar B.R., and Serody J.S. In vitro- differentiated TH17 cells mediate lethal acute graft- versus- host disease with severe cutaneous and pulmonary pathologic manifestations. Blood 113 (2009) 1365-1374
22. Mauermann N., Burian J., von Garnier C., Dirnhofer S., Germano D., Schuett C., et al. Interferon- γ regulates idiopathic pneumonia syndrome, a Th17+CD4+ T- cell- mediated graft- versus- host disease. Am J Respir Crit Care Med 178 (2008) 379-388
23. Kappel L.W., Goldberg G.L., King C.G., Suh D.Y., Smith O.M., Ligh C., et al. IL- 17 contributes to CD4- mediated graft- versus- host disease. Blood 113 (2009) 945-952
24. Yi T., Zhao D., Lin C.L., Zhang C., Chen Y., Todorov I., et al. Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft- versus- host disease. Blood 112 (2008) 2101-2110
25. Maumenee A.E. The influence of donor-recipient sensitization on corneal grafts. Am J Ophthalmol 34 (1951) 142-152
26. Williams K.A., and Coster D.J. The immunobiology of corneal transplantation. Transplantation 84 (2007) 806-813
27. Streilein J.W., Arancibia-Caracamo C., and Osawa H. The role of minor histocompatibility alloantigens in penetrating keratoplasty. Dev Ophthalmol 36 (2003) 74-88
28. Klebe S., Coster D.J., Sykes P.J., Swinburne S., Hallsworth P., Scheerlinck J.P., et al. Prolongation of sheep corneal allograft survival by transfer of the gene encoding ovine IL- 12- p40 but not IL- 4 to donor corneal endothelium. J Immunol 175 (2005) 2219-2226
29. Yamagami S., and Dana M.R. The critical role of lymph nodes in corneal alloimmunization and graft rejection. Invest Ophthalmol Vis Sci 42 (2001) 1293-1298
30. Bommireddy R., and Doetschman T. TGF- β1 and Treg cell: alliance for tolerance. Trends Mol Med 13 (2007) 492-501
31. Weaver C.T., Hatton R.D., Mangan P.R., and Harrington L.E. IL- 17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 25 (2007) 821-852
32. Yang X.O., Chang S.H., Park H., Nurieva R., Shah B., Acero L., et al. Regulation of inflammatory responses by IL- 17F. J Exp Med 205 (2008) 1063-1075
33. Yang X.O., Pappu B.P., Nurieva R., Akimzhanov A., Kang H.S., Chung Y., et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR α and ROR γ. Immunity 28 (2008) 29-39
34. Kapessidou P., Poulin L., Dumoutier L., Goldman M., Renauld J.C., and Braun M.Y. Interleukin- 22 deficiency accelerates the rejection of full major histocompatibility complex- disparate heart allografts. Transplant Proc 40 (2008) 1593-1597
35. He Y.G., Ross J., and Niederkorn J.Y. Promotion of murine orthotopic corneal allograft survival by systemic administration of anti- CD4 monoclonal antibody. Invest Ophthalmol Vis Sci 32 (1991) 2723-2728
36. Ayliffe W., Alam Y., Bell E.B., McLeod D., and Hutchinson I.V. Prolongation of rat corneal graft survival by treatment with anti- CD4 monoclonal antibody. Br J Ophthalmol 76 (1992) 602-606
37. Hargrave S.L., Hay C., Mellon J., Mayhew E., and Niederkorn J.Y. Fate of MHC- matched corneal allografts in Th1- deficient hosts. Invest Ophthalmol Vis Sci 45 (2004) 1188-1193
38. Khader S.A., Bell G.K., Pearl J.E., Fountain J.J., Rangel- Moreno J., Cilley G.E., et al. IL- 23 and IL- 17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 8 (2007) 369-377
39. Yang X.O., Nurieva R., Martinez G.J., Kang H.S., Chung Y., Pappu B.P., et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 29 (2008) 44-56
40. Osorio F., LeibundGut- Landmann S., Lochner M., Lahl K., Sparwasser T., Eberl G., et al. DC activated via dectin- 1 convert Treg into IL- 17- producers. Eur J Immunol 38 (2008) 3274-3281
41. Elias K.M., Laurence A., Davidson T.S., Stephens G., Kanno Y., Shevach E.M., et al. Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat- 3/Stat- 5 independent signaling pathway. Blood 111 (2008) 1013-1020
42. Teunissen M.B., Koomen C.W., de Waal Malefyt R., Wierenga E.A., and Bos J.D. Interleukin-17 and interferon- gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J Invest Dermatol 111 (1998) 645-649