The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing

Biochemical Pharmacology

Volumn 96, Issue 3, 2015, Pages 267-277

  Gonzalez Malagon, Sandra G ^a   Melidoni, Anna N ^b   Hernandez, Diana ^a   Omar, Bilal A ^b   Houseman, Lyndsey ^a   Veeravalli, Sunil ^a   Scott, Flora ^a   Varshavi, Dorsa ^c   Everett, Jeremy ^c   Tsuchiya, Yugo ^a   Timms, John F ^a   Phillips, Ian R ^a,b   Shephard, Elizabeth A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF GREENWICH   (United Kingdom)

Author keywords

Body weight; Cholesterol; Glucose; Malic enzyme 1; White adipose tissue

Indexed keywords

CARBOHYDRATE; CREATININE; DIMETHYLANILINE MONOOXYGENASE; FLAVIN CONTAINING MONOOXYGENASE 5; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; GLYCEROPHOSPHATE; GLYCOGEN; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; MALATE DEHYDROGENASE (DECARBOXYLATING); MALIC ACID; OXYGEN; PYRUVIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; UREA; CHOLESTEROL; DIMETHYLANILINE MONOOXYGENASE (N-OXIDE FORMING); FRUCTOKINASE; GLUCOSE BLOOD LEVEL; GLYCEROL 3 PHOSPHATE DEHYDROGENASE (NAD); KETOHEXOKINASE; MALATE DEHYDROGENASE; OXYGENASE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE ACID SYNTHESIS; BLASTOCYST; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CODON; CONGENIC STRAIN; CONTROLLED STUDY; DECARBOXYLATION; DOWN REGULATION; EPIDIDYMIS FAT; FATTY ACID OXIDATION; FEMALE; FOOD INTAKE; FRUCTOSE METABOLISM; GENE DISRUPTION; GLUCOSE BLOOD LEVEL; GLYCOGEN LIVER LEVEL; KNOCKOUT MOUSE; LUNG GAS EXCHANGE; MALE; MALIC ENZYME 1; METABOLIC AGEING; METABOLISM; MOUSE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; OXYGEN CONSUMPTION; PHENOTYPE; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RESTING ENERGY EXPENDITURE; SEX DIFFERENCE; TRANSLATION INITIATION; TRIACYLGLYCEROL BLOOD LEVEL; URINARY EXCRETION; WEIGHT GAIN; WESTERN BLOTTING; WHITE ADIPOSE TISSUE; WILD TYPE; ANIMAL; BLOOD; BODY WEIGHT; DEFICIENCY; ENERGY METABOLISM; ENZYMOLOGY; FOUNDER EFFECT; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; LIPID METABOLISM; LIVER; OXIDATION REDUCTION REACTION; SKELETAL MUSCLE;

ADIPOSE TISSUE, WHITE; AGING; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CHOLESTEROL; ENERGY METABOLISM; FOUNDER EFFECT; FRUCTOKINASES; FRUCTOSE-BISPHOSPHATE ALDOLASE; GENE EXPRESSION REGULATION; GENOTYPE; GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD+); HYDROXYMETHYLGLUTARYL-COA SYNTHASE; LIPID METABOLISM; LIVER; MALATE DEHYDROGENASE; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXYGENASES; PHENOTYPE;

EID: 84934833136     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.05.013     Document Type: Article

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