PH dependence on functional activity of human and mouse flavin-containing monooxygenase 5

Biochemical Pharmacology

Volumn 83, Issue 7, 2012, Pages 962-968

  Motika, Meike S ^a   Zhang, Jun ^a   Ralph, Erik C ^a   Dwyer, Mary A ^a   Cashman, John R ^a  

^a HUMAN BIOMOLECULAR RESEARCH INSTITUTE   (United States)

Author keywords

hFMO5 D227K; hFMO5 Y228H; Human and mouse flavin containing monooxygenase 5; pH dependent enzyme activity

Indexed keywords

AMINO ACID; DIMETHYLANILINE MONOOXYGENASE; ENZYME VARIANT; FLAVIN CONTAINING MONOOXYGENASE 5; HYBRID PROTEIN; MALTOSE BINDING PROTEIN; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ARTICLE; CATALYSIS; CHIMERA; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; HUMAN; MOLECULAR MODEL; MOUSE; NONHUMAN; NUCLEOPHILICITY; NUCLEOTIDE SEQUENCE; OXYGENATION; PH; PRIORITY JOURNAL;

ANIMALS; CLONING, MOLECULAR; ESCHERICHIA COLI; HUMANS; HYDROGEN-ION CONCENTRATION; MALTOSE-BINDING PROTEINS; MICE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; OXYGENASES; PHENOTHIAZINES; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS; SPECIES SPECIFICITY;

EID: 84862829079     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.01.006     Document Type: Article

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