-
1
-
-
51549117737
-
-
National Cancer Institute; Bethesda, MD based on November 2013 SEER data submission, posted to the SEER web site
-
Ries LAG, Melbert D, Krapcho M et al (2014) SEER cancer statistics review, 1975-2014. National Cancer Institute; Bethesda, MD. http://seer.cancer.gov/statfacts/html/corp.html, based on November 2013 SEER data submission, posted to the SEER web site
-
(2014)
SEER Cancer Statistics Review, 1975-2014
-
-
Ries, L.A.G.1
Melbert, D.2
Krapcho, M.3
-
2
-
-
38749134447
-
Novel molecular profiles of endometrial cancer new light through hold windows
-
1:CAS:528:DC%2BD1cXhsFyntb0%3D 18061438
-
Doll A, Abal M, Rigau M et al (2008) Novel molecular profiles of endometrial cancer new light through hold windows. J Steroid Biochem Mol Biol 108(3-5):221-229
-
(2008)
J Steroid Biochem Mol Biol
, vol.108
, Issue.3-5
, pp. 221-229
-
-
Doll, A.1
Abal, M.2
Rigau, M.3
-
3
-
-
0020660717
-
Two pathogenetic types of endometrial carcinoma
-
1:STN:280:DyaL3s7gs1KktA%3D%3D 6822361
-
Bokhman JV (1983) Two pathogenetic types of endometrial carcinoma. Gynecol Oncol 15(1):10-17
-
(1983)
Gynecol Oncol
, vol.15
, Issue.1
, pp. 10-17
-
-
Bokhman, J.V.1
-
4
-
-
0028829840
-
Endometrial intraepithelial carcinoma: A distinctive lesion specifically associated with tumors displaying serous differentiation
-
1:STN:280:DyaK28%2FmvVOruw%3D%3D 7590702
-
Ambros RA, Sherman ME, Zahn CM, Bitterman P, Kurman RJ (1995) Endometrial intraepithelial carcinoma: a distinctive lesion specifically associated with tumors displaying serous differentiation. Hum Pathol 26:1260-1267
-
(1995)
Hum Pathol
, vol.26
, pp. 1260-1267
-
-
Ambros, R.A.1
Sherman, M.E.2
Zahn, C.M.3
Bitterman, P.4
Kurman, R.J.5
-
5
-
-
84877254190
-
Integrated genomic characterization of endometrial carcinoma
-
23636398
-
Kandoth C, Schultz N, Cherniack AD, Akbani R, Liu Y, Shen H, Robertson AG, Pashtan I (2013) Integrated genomic characterization of endometrial carcinoma. Nature 497(7447):67-73
-
(2013)
Nature
, vol.497
, Issue.7447
, pp. 67-73
-
-
Kandoth, C.1
Schultz, N.2
Cherniack, A.D.3
Akbani, R.4
Liu, Y.5
Shen, H.6
Robertson, A.G.7
Pashtan, I.8
-
6
-
-
77955919147
-
Serum tumour markers in gynaecological cancers
-
1:CAS:528:DC%2BC3cXhtVaqsb%2FO 20510555
-
Aggarwal P, Kehoe S (2010) Serum tumour markers in gynaecological cancers. Maturitas 67:46-53
-
(2010)
Maturitas
, vol.67
, pp. 46-53
-
-
Aggarwal, P.1
Kehoe, S.2
-
7
-
-
33750576103
-
Molecular and pathologic aspects of endometrial carcinogenesis
-
1:CAS:528:DC%2BD28XhtFynsrrO 17028294
-
Hecht Jonathan L, Mutter George L (2006) Molecular and pathologic aspects of endometrial carcinogenesis. J Clin Oncol 24(29):4783-4791
-
(2006)
J Clin Oncol
, vol.24
, Issue.29
, pp. 4783-4791
-
-
Hecht, J.L.1
Mutter, G.L.2
-
8
-
-
84929904905
-
Evidence for different expression profiles for c-Met, EGFR, PTEN and the mTOR pathway in low and high grade endometrial carcinomas in a cohort of consecutive women
-
Thoury A, Descatoire V, Kotelevets L, Kannengiesser C, Bertrand G, Theou-Anton N, Frey C, Genestie C, Raymond E, Chastre E, Lehy T, Walker F (2014) Evidence for different expression profiles for c-Met, EGFR, PTEN and the mTOR pathway in low and high grade endometrial carcinomas in a cohort of consecutive women. Occurrence of PIK3CA and K-Ras mutations and microsatellite instability. Histol Histopathol 29(11):1455-1466
-
(2014)
Occurrence of PIK3CA and K-Ras Mutations and Microsatellite Instability. Histol Histopathol
, vol.29
, Issue.11
, pp. 1455-1466
-
-
Thoury, A.1
Descatoire, V.2
Kotelevets, L.3
Kannengiesser, C.4
Bertrand, G.5
Theou-Anton, N.6
Frey, C.7
Genestie, C.8
Raymond, E.9
Chastre, E.10
Lehy, T.11
Walker, F.12
-
9
-
-
84892992470
-
Heinen: Translating mismatch repair mechanism into cancer care
-
Heinen CD (2014) Translating mismatch repair mechanism into cancer care. Curr Drug Targ 15:53-64
-
(2014)
Curr Drug Targ
, vol.15
, pp. 53-64
-
-
Christopher, D.1
-
10
-
-
0029883728
-
Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma
-
1:STN:280:DyaK283gvVWnsw%3D%3D 1861548 8623934
-
Caduff RF, Johnston CM, Svoboda-Newman SM, Poy EL, Merajver SD, Frank TS (1996) Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma. Am J Pathol 148:1671-1678
-
(1996)
Am J Pathol
, vol.148
, pp. 1671-1678
-
-
Caduff, R.F.1
Johnston, C.M.2
Svoboda-Newman, S.M.3
Poy, E.L.4
Merajver, S.D.5
Frank, T.S.6
-
11
-
-
0032487831
-
MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas
-
1:CAS:528:DyaK1cXns12mtr4%3D 9811473
-
Esteller M, Levine R, Baylin SB, Ellenson LH, Herman JG (1998) MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas. Oncogene 17:2413-2417
-
(1998)
Oncogene
, vol.17
, pp. 2413-2417
-
-
Esteller, M.1
Levine, R.2
Baylin, S.B.3
Ellenson, L.H.4
Herman, J.G.5
-
12
-
-
0031823235
-
Analysis of MSH3 in endometrial cancers with defective DNA mismatch repair
-
1:CAS:528:DyaK1cXlsFWrtrg%3D 9699180
-
Swisher EM, Mutch DG, Herzog TJ et al (1998) Analysis of MSH3 in endometrial cancers with defective DNA mismatch repair. J Soc Gynecol Investig 5:210-216
-
(1998)
J Soc Gynecol Investig
, vol.5
, pp. 210-216
-
-
Swisher, E.M.1
Mutch, D.G.2
Herzog, T.J.3
-
13
-
-
33745450851
-
The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer
-
1:CAS:528:DC%2BD28Xmtlyjs74%3D 16506206
-
Bilbao C, Rodrlguez G, Ramlrez R, Falcon O, Leon L, Chirino R, Rivero JF et al (2006) The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer. Int J Cancer 119:563-570
-
(2006)
Int J Cancer
, vol.119
, pp. 563-570
-
-
Bilbao, C.1
Rodrlguez, G.2
Ramlrez, R.3
Falcon, O.4
Leon, L.5
Chirino, R.6
Rivero, J.F.7
-
14
-
-
0033774009
-
Absence of PTEN repeat tract mutation in endome- microsatellite instability
-
1:CAS:528:DC%2BD3cXmslKns7w%3D 11006040
-
Cohn DE, Basil JB, Venegoni AR et al (2000) Absence of PTEN repeat tract mutation in endome- microsatellite instability. Gynecol Oncol 79:101-106
-
(2000)
Gynecol Oncol
, vol.79
, pp. 101-106
-
-
Cohn, D.E.1
Basil, J.B.2
Venegoni, A.R.3
-
15
-
-
0027285475
-
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
-
1:CAS:528:DyaK3sXks12hu7c%3D 8505985
-
Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363:558-561
-
(1993)
Nature
, vol.363
, pp. 558-561
-
-
Ionov, Y.1
Peinado, M.A.2
Malkhosyan, S.3
Shibata, D.4
Perucho, M.5
-
16
-
-
0033083214
-
Microsatellite instability impact on cancer progression in proximal and distal colorectal cancers
-
1:STN:280:DyaK1Mznslelug%3D%3D 10448259
-
Jernvall P, Makinen MJ, Karttunen TJ, Makela J, Vihko P (1999) Microsatellite instability impact on cancer progression in proximal and distal colorectal cancers. Eur J Cancer 35:197-201
-
(1999)
Eur J Cancer
, vol.35
, pp. 197-201
-
-
Jernvall, P.1
Makinen, M.J.2
Karttunen, T.J.3
Makela, J.4
Vihko, P.5
-
17
-
-
0032815220
-
Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variables
-
1:STN:280:DyaK1MzpvFWjtQ%3D%3D 10470121
-
Johannsdottir JT, Bergthorsson JT, Gretarsdottir S, Kristjans-son AK, Ragnarsson G, Jonasson JG et al (1999) Replication error in colorectal carcinoma: association with loss of heterozygosity at mismatch repair loci and clinicopathological variables. Anticancer Res 19:1821-1826
-
(1999)
Anticancer Res
, vol.19
, pp. 1821-1826
-
-
Johannsdottir, J.T.1
Bergthorsson, J.T.2
Gretarsdottir, S.3
Kristjans-Son, A.K.4
Ragnarsson, G.5
Jonasson, J.G.6
-
18
-
-
0031690464
-
Microsatellite instability in endometrial carcinomas: Clinicopathologic correlations in a series of 42 cases
-
1:CAS:528:DyaK1cXntFGgsbY%3D 9781658
-
Catasus L, Machin P, Matias-Guiu X, Prat J (1998) Microsatellite instability in endometrial carcinomas: clinicopathologic correlations in a series of 42 cases. Hum Path 29:1160-1164
-
(1998)
Hum Path
, vol.29
, pp. 1160-1164
-
-
Catasus, L.1
Machin, P.2
Matias-Guiu, X.3
Prat, J.4
-
19
-
-
84870532408
-
Randomized phase III noninferiority trial of first line chemotherapy for metastatic or recurrent endometrial carcinoma: A gynecologic oncology group study
-
Miller D, Filiaci V, Fleming G et al (2012) Randomized phase III noninferiority trial of first line chemotherapy for metastatic or recurrent endometrial carcinoma: a gynecologic oncology group study. Gynecol Oncol 125:771-773
-
(2012)
Gynecol Oncol
, vol.125
, pp. 771-773
-
-
Miller, D.1
Filiaci, V.2
Fleming, G.3
-
20
-
-
0034978311
-
PTEN, a protean tumor suppressor
-
1:CAS:528:DC%2BD3MXkvFyks7c%3D 1891981 11395362
-
Mutter GL (2001) PTEN, a protean tumor suppressor. Am J Pathol 158:1895-1898
-
(2001)
Am J Pathol
, vol.158
, pp. 1895-1898
-
-
Mutter, G.L.1
-
21
-
-
0034616634
-
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers
-
Mutter GL, Lin MC et al (2000) Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers. J Nat Can Inst 92:11
-
(2000)
J Nat Can Inst
, vol.92
, pp. 11
-
-
Mutter, G.L.1
Lin, M.C.2
-
22
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
1:CAS:528:DyaK2sXmtFehs7g%3D 9307275
-
Tashiro H, Blazes MS, Wu R, Cho KR, Bose S, Wang SI et al (1997) Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 57:3935-3940
-
(1997)
Cancer Res
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.6
-
24
-
-
84893821223
-
Molecular Alterations of PI3K/Akt/mTOR pathway: A therapeutic target in endometrial cancer
-
Art id 709736
-
Pavlidou A, Vlahos NF (2014) Molecular Alterations of PI3K/Akt/mTOR pathway: a therapeutic target in endometrial cancer. Sci World J, Art id 709736
-
(2014)
Sci World J
-
-
Pavlidou, A.1
Vlahos, N.F.2
-
25
-
-
79958820962
-
PIK3R1 (p85a) is somatically mutated at high frequency in primary endometrial cancer
-
1:CAS:528:DC%2BC3MXnsFKiu7w%3D
-
Urick ME, Rudd ML, Godwin AK, Sgroi D, Merino M, Bell DW (2011) PIK3R1 (p85a) is somatically mutated at high frequency in primary endometrial cancer. Can Resear 71(12):4061-4067
-
(2011)
Can Resear
, vol.71
, Issue.12
, pp. 4061-4067
-
-
Urick, M.E.1
Rudd, M.L.2
Godwin, A.K.3
Sgroi, D.4
Merino, M.5
Bell, D.W.6
-
26
-
-
80054778946
-
High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability
-
Cheung LW et al (2011) High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability. Cancer Discov 2:170-185
-
(2011)
Cancer Discov
, vol.2
, pp. 170-185
-
-
Cheung, L.W.1
-
27
-
-
78649592049
-
A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma
-
1:CAS:528:DC%2BC3cXhs1WnurzK 20681032
-
Slomovitz BM, Lu KH, Johnston T et al (2010) A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma. Cancer 116(23):5415-5419
-
(2010)
Cancer
, vol.116
, Issue.23
, pp. 5415-5419
-
-
Slomovitz, B.M.1
Lu, K.H.2
Johnston, T.3
-
28
-
-
0037178786
-
MTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
1:CAS:528:DC%2BD38XlvV2htr4%3D 12150925
-
Kim DH, Sarbassov DD, Ali SM et al (2002) mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110(2):163-175
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
-
29
-
-
67649868092
-
The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas
-
1:CAS:528:DC%2BD1MXotVKgur4%3D 2713716 19491896
-
Shoji K, Oda K, Nakagawa S et al (2009) The oncogenic mutation in the pleckstrin homology domain of AKT1 in endometrial carcinomas. Br J Cancer 101(1):145-148
-
(2009)
Br J Cancer
, vol.101
, Issue.1
, pp. 145-148
-
-
Shoji, K.1
Oda, K.2
Nakagawa, S.3
-
30
-
-
0032953788
-
Differences in patterns of TP53 and KRAS2 mutations in a large series of endometrial carcinomas with or without microsatellite instability
-
1:CAS:528:DyaK1MXmsVemsA%3D%3D 9921983
-
Swisher EM, Peiffer-Schneider S, Mutch DG et al (1999) Differences in patterns of TP53 and KRAS2 mutations in a large series of endometrial carcinomas with or without microsatellite instability. Cancer 85:119-126
-
(1999)
Cancer
, vol.85
, pp. 119-126
-
-
Swisher, E.M.1
Peiffer-Schneider, S.2
Mutch, D.G.3
-
31
-
-
0034651530
-
The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: Evidence of distinct molecular genetic pathways
-
1:CAS:528:DC%2BD3cXhtlGntbk%3D 10679651
-
Lax SF, Kendall B, Tashiro H et al (2000) The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways. Cancer 88:814-824
-
(2000)
Cancer
, vol.88
, pp. 814-824
-
-
Lax, S.F.1
Kendall, B.2
Tashiro, H.3
-
32
-
-
0035150494
-
K-ras mutations in endometrial carcinomas with microsatellite instability
-
1:CAS:528:DC%2BD3MXhtFGqtbo%3D 11180166
-
Lagarda H et al (2001) K-ras mutations in endometrial carcinomas with microsatellite instability. J Path 193(2):193-199
-
(2001)
J Path
, vol.193
, Issue.2
, pp. 193-199
-
-
Lagarda, H.1
-
33
-
-
0030978351
-
Beta-catenin is a target for the ubiquitin-proteasome pathway
-
1:CAS:528:DyaK2sXkslShsbk%3D 1170003 9233789
-
Aberle H, Bauer A, Stappert J, Kispert A, Kemler R (1997) beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J 16(13):3797-3804
-
(1997)
EMBO J
, vol.16
, Issue.13
, pp. 3797-3804
-
-
Aberle, H.1
Bauer, A.2
Stappert, J.3
Kispert, A.4
Kemler, R.5
-
34
-
-
0031984835
-
Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: Correlation with disease progression and dedifferentiation
-
1:CAS:528:DyaK1cXktlyntw%3D%3D 1858126 9422531
-
Bailey T, Biddlestone L, Shepherd N, Barr H, Warner P, Jankowski J (1998) Altered cadherin and catenin complexes in the Barrett's esophagus-dysplasia-adenocarcinoma sequence: correlation with disease progression and dedifferentiation. Am J Pathol 152(1):135-144
-
(1998)
Am J Pathol
, vol.152
, Issue.1
, pp. 135-144
-
-
Bailey, T.1
Biddlestone, L.2
Shepherd, N.3
Barr, H.4
Warner, P.5
Jankowski, J.6
-
35
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
-
9554852
-
Wirtz R, Kuhl M, Wedlich D, Birchmeier W (1998) Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 280:596-599
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Wirtz, R.1
Kuhl, M.2
Wedlich, D.3
Birchmeier, W.4
-
36
-
-
0036957026
-
Expression of E-cadherin and alpha-, beta-, gamma-catenin proteins in endometrial carcinoma
-
1:CAS:528:DC%2BD3sXot1Clsg%3D%3D 12497652
-
Kim YT, Choi EK, Kim JW et al (2002) Expression of E-cadherin and alpha-, beta-, gamma-catenin proteins in endometrial carcinoma. Yonsei Med J 43:701-711
-
(2002)
Yonsei Med J
, vol.43
, pp. 701-711
-
-
Kim, Y.T.1
Choi, E.K.2
Kim, J.W.3
-
37
-
-
14944385644
-
Immunohistochemical expression of E-cadherin and beta-catenin in the normal and malignant human endometrium: An inverse correlation between E-cadherin and nuclear beta-catenin expression
-
1:CAS:528:DC%2BD2MXitFylsLg%3D 15736420
-
Shih HC, Shiozawa T, Miyamoto T et al (2004) Immunohistochemical expression of E-cadherin and beta-catenin in the normal and malignant human endometrium: an inverse correlation between E-cadherin and nuclear beta-catenin expression. Anticancer Res 24:3843-3850
-
(2004)
Anticancer Res
, vol.24
, pp. 3843-3850
-
-
Shih, H.C.1
Shiozawa, T.2
Miyamoto, T.3
-
38
-
-
0033545845
-
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
-
1:CAS:528:DyaK1MXjtFCnsbc%3D 21892 10318916
-
Shtutman M, Zhurinsky J, Simcha I et al (1999) The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci USA 96:5522-5527
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
-
40
-
-
48749094526
-
Cancer genomics and genetics of FGFR2 (Review)
-
1:CAS:528:DC%2BD1cXhtV2lsbzP 18636142
-
Katoh M (2008) Cancer genomics and genetics of FGFR2 (Review). Int J Oncol 33:233-237
-
(2008)
Int J Oncol
, vol.33
, pp. 233-237
-
-
Katoh, M.1
-
41
-
-
52049086201
-
Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation
-
1:CAS:528:DC%2BD1cXhtVCrs7%2FO 18757403
-
Byron SA, Gartside MG, Wellens CL et al (2008) Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation. Cancer Res 68:6902
-
(2008)
Cancer Res
, vol.68
, pp. 6902
-
-
Byron, S.A.1
Gartside, M.G.2
Wellens, C.L.3
-
42
-
-
47249122523
-
Drug-sensitive FGFR2 mutations in endometrial carcinoma
-
1:CAS:528:DC%2BD1cXot1agtLw%3D 2438391 18552176
-
Dutt A, Salvesen HB, Chen TH et al (2008) Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc Natl Acad Sci USA 105:8713
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8713
-
-
Dutt, A.1
Salvesen, H.B.2
Chen, T.H.3
-
43
-
-
80455164694
-
FGFR2 alterations in endometrial carcinoma
-
1:CAS:528:DC%2BC3MXhsVagt77M
-
Gatius S, Velasco A, Azueta A, Santacana M et al (2011) FGFR2 alterations in endometrial carcinoma. Modern Path 24:1500-1510
-
(2011)
Modern Path
, vol.24
, pp. 1500-1510
-
-
Gatius, S.1
Velasco, A.2
Azueta, A.3
Santacana, M.4
-
44
-
-
4544379915
-
Molecular differences between RER + and RER- sporadic endometrial carcinomas in a large population-based series
-
1:STN:280:DC%2BD2cvlt1Kktw%3D%3D 15361209
-
Macdonald ND, Salvesen HB, Ryan A, Malatos S, Stefansson I, Iversen OE et al (2004) Molecular differences between RER + and RER- sporadic endometrial carcinomas in a large population-based series. Int J Gynecol Cancer 14:957-965
-
(2004)
Int J Gynecol Cancer
, vol.14
, pp. 957-965
-
-
Macdonald, N.D.1
Salvesen, H.B.2
Ryan, A.3
Malatos, S.4
Stefansson, I.5
Iversen, O.E.6
-
45
-
-
0344241483
-
Promoter hypermethylation as an epigenetic component in Type i and Type II endometrial cancers
-
1:CAS:528:DC%2BD3sXjt1yrsLk%3D 12724225
-
Risinger JI, Maxwell GL, Berchuck A, Barrett JC (2003) Promoter hypermethylation as an epigenetic component in Type I and Type II endometrial cancers. Ann N Y Acad Sci 983:208-212
-
(2003)
Ann N y Acad Sci
, vol.983
, pp. 208-212
-
-
Risinger, J.I.1
Maxwell, G.L.2
Berchuck, A.3
Barrett, J.C.4
-
46
-
-
0032945849
-
Mutations and amplification of oncogenes in endometrial cancer
-
1:CAS:528:DyaK1MXhtV2ls7s%3D 9885379
-
Niederacher D, An HX, Cho YJ, Hantschmann P, Bender HG, Beckmann MW (1999) Mutations and amplification of oncogenes in endometrial cancer. Oncology 56:59-65
-
(1999)
Oncology
, vol.56
, pp. 59-65
-
-
Niederacher, D.1
An, H.X.2
Cho, Y.J.3
Hantschmann, P.4
Bender, H.G.5
Beckmann, M.W.6
-
47
-
-
0028889465
-
Amplification and overexpression of HER-2/neu (c-erbB2) in endome- trial cancers: Correlation with overall survival
-
1:CAS:528:DyaK2MXps1Krurc%3D 7585656
-
Saffari B, Jones LA, El-Naggar A, Felix JC, George J, Press MF (1995) Amplification and overexpression of HER-2/neu (c-erbB2) in endome- trial cancers: correlation with overall survival. Cancer Res 55:5693-5698
-
(1995)
Cancer Res
, vol.55
, pp. 5693-5698
-
-
Saffari, B.1
Jones, L.A.2
El-Naggar, A.3
Felix, J.C.4
George, J.5
Press, M.F.6
-
48
-
-
0028032493
-
The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer
-
1:STN:280:DyaK2M%2FmvF2hsQ%3D%3D 7979205
-
Vasen HF, Watson P, Mecklin JP et al (1994) The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer. Anticancer Res 14:1675-1678
-
(1994)
Anticancer Res
, vol.14
, pp. 1675-1678
-
-
Vasen, H.F.1
Watson, P.2
Mecklin, J.P.3
-
49
-
-
0030882381
-
Mutations predisposing to hereditary nonpolyposis colorectal cancer: Database and results of a collaborative study
-
The International Collaborative Group on HNPCC 1:CAS:528:DyaK2sXmslOlsLg%3D 9322509
-
Peltomaki P, Vasen HF, The International Collaborative Group on HNPCC (1997) Mutations predisposing to hereditary nonpolyposis colorectal cancer: database and results of a collaborative study. Gastroenterology 113:1146-1158
-
(1997)
Gastroenterology
, vol.113
, pp. 1146-1158
-
-
Peltomaki, P.1
Vasen, H.F.2
-
50
-
-
0032759135
-
Fluorescence in situ hybridization analysis of HER-2/neu, c-myc, and p53 in endometrial cancer
-
1:CAS:528:DyaK1MXnvFaqsbw%3D 10600396
-
Williams JA Jr, Wang ZR, Parrish RS, Hazlett LJ, Smith ST, Young SR (1999) Fluorescence in situ hybridization analysis of HER-2/neu, c-myc, and p53 in endometrial cancer. Exp Mol Pathol 67:135-143
-
(1999)
Exp Mol Pathol
, vol.67
, pp. 135-143
-
-
Williams, Jr.J.A.1
Wang, Z.R.2
Parrish, R.S.3
Hazlett, L.J.4
Smith, S.T.5
Young, S.R.6
-
52
-
-
0031278322
-
Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
-
1:CAS:528:DyaK2sXntVShtbg%3D 9354786
-
Miyaki M, Konishi M, Tanaka K et al (1997) Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet 17:271-272
-
(1997)
Nat Genet
, vol.17
, pp. 271-272
-
-
Miyaki, M.1
Konishi, M.2
Tanaka, K.3
-
53
-
-
0035300475
-
Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer
-
1:CAS:528:DC%2BD3MXivFGrur0%3D 11306449
-
Schweizer P, Moisio AL, Kuismanen SA et al (2001) Lack of MSH2 and MSH6 characterizes endometrial but not colon carcinomas in hereditary nonpolyposis colorectal cancer. Cancer Res 61:2813-2815
-
(2001)
Cancer Res
, vol.61
, pp. 2813-2815
-
-
Schweizer, P.1
Moisio, A.L.2
Kuismanen, S.A.3
-
54
-
-
84988273336
-
Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: Association with family history and histopathology
-
1:CAS:528:DC%2BD3cXitVegt7k%3D 10728595
-
Parc YR, Halling KC, Burgart LJ et al (2000) Microsatellite instability and hMLH1/hMSH2 expression in young endometrial carcinoma patients: association with family history and histopathology. Int J Cancer 86:60-66
-
(2000)
Int J Cancer
, vol.86
, pp. 60-66
-
-
Parc, Y.R.1
Halling, K.C.2
Burgart, L.J.3
-
55
-
-
0033645557
-
Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumors from HNPCC patients
-
11054716
-
De Leeuw WJ, Dierssen J, Vasen HF et al (2000) Prediction of a mismatch repair gene defect by microsatellite instability and immunohistochemical analysis in endometrial tumors from HNPCC patients. J Pathol 192:328-335
-
(2000)
J Pathol
, vol.192
, pp. 328-335
-
-
De Leeuw, W.J.1
Dierssen, J.2
Vasen, H.F.3
-
56
-
-
0031893552
-
Familial endometrial adenocarcinoma
-
1:STN:280:DyaK1c7msV2qtg%3D%3D 9504234
-
Sandles LG (1998) Familial endometrial adenocarcinoma. Clin Obstet Gynecol 41:167-171
-
(1998)
Clin Obstet Gynecol
, vol.41
, pp. 167-171
-
-
Sandles, L.G.1
-
57
-
-
23044501891
-
Molecular analysis of familial endometrial carcinoma: A manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome?
-
1:CAS:528:DC%2BD2MXotFarsrs%3D 15837969
-
Ollikainen M, Abdel-Rahman WM, Moisio AL et al (2005) Molecular analysis of familial endometrial carcinoma: a manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome? J Clin Oncol 23:4609-4616
-
(2005)
J Clin Oncol
, vol.23
, pp. 4609-4616
-
-
Ollikainen, M.1
Abdel-Rahman, W.M.2
Moisio, A.L.3
-
58
-
-
79957949444
-
Phase II trial of bevacizumab in recurrent or persistent endometrial cancer: A gynecologic oncology group study
-
1:CAS:528:DC%2BC3MXptVOkt7c%3D 3107744 21537039
-
Aghajanian C, Sill MW, Darcy KM et al (2011) Phase II trial of bevacizumab in recurrent or persistent endometrial cancer: a gynecologic oncology group study. J Clin Oncol 29:2259-2265
-
(2011)
J Clin Oncol
, vol.29
, pp. 2259-2265
-
-
Aghajanian, C.1
Sill, M.W.2
Darcy, K.M.3
-
59
-
-
84934441567
-
-
National Cancer Institute Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT 00977574
-
National Cancer Institute (2000) Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in treating patients with stage III, Stage IV, or Recurrent Endometrial Cancer. Bethesda (MD): National Library of Medicine (US). http://clinicaltrials.gov/show/NCT00977574 NLM identifier: NCT 00977574
-
(2000)
Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients with Stage III, Stage IV, or Recurrent Endometrial Cancer
-
-
-
60
-
-
84868588283
-
A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: A gynecologic oncology group study
-
1:CAS:528:DC%2BC38XhtlSnsr7I 3568489 22922531
-
Coleman RL, Sill MW, Lankes HA et al (2012) A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: a gynecologic oncology group study. Gynecol Oncol 127:538-543
-
(2012)
Gynecol Oncol
, vol.127
, pp. 538-543
-
-
Coleman, R.L.1
Sill, M.W.2
Lankes, H.A.3
-
61
-
-
34247128217
-
A phase II trial of thalidomide in patients with refractory endometrial cancer and correlation with angiogenesis biomarkers: A gynecologic oncology group study
-
1:CAS:528:DC%2BD2sXksVOms74%3D 1931832 17306350
-
McMeekin DS, Sill MW, Benbrook D et al (2007) A phase II trial of thalidomide in patients with refractory endometrial cancer and correlation with angiogenesis biomarkers: a gynecologic oncology group study. Gynecol Oncol 105:508-516
-
(2007)
Gynecol Oncol
, vol.105
, pp. 508-516
-
-
McMeekin, D.S.1
Sill, M.W.2
Benbrook, D.3
-
62
-
-
84905568519
-
A phase II trial of sunitinib in women with metastatic or recurrent endometrial carcinoma: A study of the Princess Margaret, Chicago and California Consortia
-
1:CAS:528:DC%2BC2cXhtVaisL%2FL 24882554
-
Castonguay V, Lheureux S, Welch S, Mackay HJ et al (2014) A phase II trial of sunitinib in women with metastatic or recurrent endometrial carcinoma: a study of the Princess Margaret, Chicago and California Consortia. Gynecol Oncol 134:274-280
-
(2014)
Gynecol Oncol
, vol.134
, pp. 274-280
-
-
Castonguay, V.1
Lheureux, S.2
Welch, S.3
Mackay, H.J.4
-
63
-
-
52049125733
-
Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCIC-148
-
1:CAS:528:DC%2BD1cXhtF2it7fN 18591547
-
Oza AM, Eisenhauer EA, Elit L, Cutz JC, Sakurada A et al (2008) Phase II study of erlotinib in recurrent or metastatic endometrial cancer: NCIC-148. J Clin Oncol 26:4319-4432
-
(2008)
J Clin Oncol
, vol.26
, pp. 4319-4432
-
-
Oza, A.M.1
Eisenhauer, E.A.2
Elit, L.3
Cutz, J.C.4
Sakurada, A.5
-
64
-
-
74249102857
-
Efficacy and safety of gefitinib and potential prognostic value of soluble EGFR, EGFR mutations, and tumor markers in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer
-
Leslie KK, Sill MW, Darcy KM et al (2009) Efficacy and safety of gefitinib and potential prognostic value of soluble EGFR, EGFR mutations, and tumor markers in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer. J Clin Oncol 27:e16542
-
(2009)
J Clin Oncol
, vol.27
, pp. e16542
-
-
Leslie, K.K.1
Sill, M.W.2
Darcy, K.M.3
-
65
-
-
46749152126
-
Trastuzumab treatment in patients with advanced or recurrent endometrial carcinoma overexpressing HER2/neu
-
1:CAS:528:DC%2BD1cXosVyiu7Y%3D 18555254
-
Santin AD, Bellone S, Roman JJ, McKenney JK, Pecorelli S (2008) Trastuzumab treatment in patients with advanced or recurrent endometrial carcinoma overexpressing HER2/neu. Int J Gynaecol Obstet 102(2):128-131
-
(2008)
Int J Gynaecol Obstet
, vol.102
, Issue.2
, pp. 128-131
-
-
Santin, A.D.1
Bellone, S.2
Roman, J.J.3
McKenney, J.K.4
Pecorelli, S.5
-
66
-
-
33745100721
-
Use of trastuzumab in the treatment of metastatic endometrial cancer
-
1:STN:280:DC%2BD28zoslemsw%3D%3D 16803532
-
Jewell E, Secord AA, Brotherton T, Berchuck A (2006) Use of trastuzumab in the treatment of metastatic endometrial cancer. Int J Gynecol Cancer 16(3):1370-1373
-
(2006)
Int J Gynecol Cancer
, vol.16
, Issue.3
, pp. 1370-1373
-
-
Jewell, E.1
Secord, A.A.2
Brotherton, T.3
Berchuck, A.4
-
67
-
-
33749144509
-
HER-2/neu overexpression in uterine papillary serous cancers and its possible therapeutic implications
-
1:STN:280:DC%2BD28rotFKgtA%3D%3D 17009989
-
Villella JA, Cohen S, Smith DH, Hibshoosh H, Hershman D (2006) HER-2/neu overexpression in uterine papillary serous cancers and its possible therapeutic implications. Int J Gynecol Cancer 16(5):1897-1902
-
(2006)
Int J Gynecol Cancer
, vol.16
, Issue.5
, pp. 1897-1902
-
-
Villella, J.A.1
Cohen, S.2
Smith, D.H.3
Hibshoosh, H.4
Hershman, D.5
-
68
-
-
70749097152
-
Phase II trial of trastuzumab in women with advanced or recurrent, HER2-positive endometrial carcinoma: A Gynecologic Oncology Group study
-
1:CAS:528:DC%2BD1MXhsFahsbbE 2804260 19840887
-
Fleming GF, Sill MW, Darcy KM, McMeekin DS, Thigpen JT, Adler LM et al (2010) Phase II trial of trastuzumab in women with advanced or recurrent, HER2-positive endometrial carcinoma: a Gynecologic Oncology Group study. Gynecol Oncol 116(1):15-20
-
(2010)
Gynecol Oncol
, vol.116
, Issue.1
, pp. 15-20
-
-
Fleming, G.F.1
Sill, M.W.2
Darcy, K.M.3
McMeekin, D.S.4
Thigpen, J.T.5
Adler, L.M.6
-
69
-
-
74249095141
-
In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma
-
1:CAS:528:DC%2BC3cXhtFOrtg%3D%3D 2813756 19920829
-
El-Sahwi K, Bellone S, Cocco E, Cargnelutti M, Casagrande F, Bellone M et al (2010) In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma. Br J Cancer 102(1):134-143
-
(2010)
Br J Cancer
, vol.102
, Issue.1
, pp. 134-143
-
-
El-Sahwi, K.1
Bellone, S.2
Cocco, E.3
Cargnelutti, M.4
Casagrande, F.5
Bellone, M.6
-
70
-
-
84867402557
-
Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Groupphase II trial of persistent or recurrent endometrial cancer
-
1:CAS:528:DC%2BC38XhtlSntr3F 3518448 22885469
-
Leslie KK, Sill MW, Lankes HA, Fischer EG, Godwin AK, Gray H et al (2012) Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Groupphase II trial of persistent or recurrent endometrial cancer. Gynecol Oncol 127(2):345-350
-
(2012)
Gynecol Oncol
, vol.127
, Issue.2
, pp. 345-350
-
-
Leslie, K.K.1
Sill, M.W.2
Lankes, H.A.3
Fischer, E.G.4
Godwin, A.K.5
Gray, H.6
-
71
-
-
84907977042
-
Neratinib shows efficacy in the treatment of HER2/neu amplified uterine serous carcinoma in vitro and in vivo
-
1:CAS:528:DC%2BC2cXhtlKrsLvE
-
Schwab CL, English DP, Roque DM, Bellone S et al (2014) Neratinib shows efficacy in the treatment of HER2/neu amplified uterine serous carcinoma in vitro and in vivo. Gynec Oncol 135:142-148
-
(2014)
Gynec Oncol
, vol.135
, pp. 142-148
-
-
Schwab, C.L.1
English, D.P.2
Roque, D.M.3
Bellone, S.4
-
72
-
-
51849155119
-
A phase II study of temsirolimus (CCI-779) in patients with metastatic and/or locally advanced recurrent endometrial cancer previously treated with chemotherapy: NCIC CTG IND 160 b
-
Oza AM, Elit L, Provencher D et al (2008) A phase II study of temsirolimus (CCI-779) in patients with metastatic and/or locally advanced recurrent endometrial cancer previously treated with chemotherapy: NCIC CTG IND 160 b. J Clin Oncol 26:e5516
-
(2008)
J Clin Oncol
, vol.26
, pp. e5516
-
-
Oza, A.M.1
Elit, L.2
Provencher, D.3
-
73
-
-
84886027192
-
Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer
-
Rachel RA, Jamal R, Tu D, Walsh W, Dancey J et al (2013) Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer. Gynec Oncol 131:315-320
-
(2013)
Gynec Oncol
, vol.131
, pp. 315-320
-
-
Rachel, R.A.1
Jamal, R.2
Tu, D.3
Walsh, W.4
Dancey, J.5
-
74
-
-
84875539239
-
Phase II trial of combination bevacizumab and temsirolimus in the treatment of recurrent or persistent endometrial carcinoma: A gynecologic oncology group study
-
1:CAS:528:DC%2BC3sXhsV2isLY%3D 23262204
-
Alvarez EA, Brady WE, Walker JL, Rotmensch J, Zhou XC, Kendrick JE (2013) Phase II trial of combination bevacizumab and temsirolimus in the treatment of recurrent or persistent endometrial carcinoma: a gynecologic oncology group study. Gynecol Oncol 129:22-27
-
(2013)
Gynecol Oncol
, vol.129
, pp. 22-27
-
-
Alvarez, E.A.1
Brady, W.E.2
Walker, J.L.3
Rotmensch, J.4
Zhou, X.C.5
Kendrick, J.E.6
-
75
-
-
84919477496
-
Temsirolimus and pegylated liposomal doxorubicin (PLD) combination therapy in breast, endometrial, and ovarian cancer: Phase Ib results and prediction of clinical outcome with FDG-PET/CT
-
24577626
-
Boers-Sonderen MJ, Geus-Oei LF, Desar IME, Van der Graaf WTA, Oyen WJG (2014) Temsirolimus and pegylated liposomal doxorubicin (PLD) combination therapy in breast, endometrial, and ovarian cancer: phase Ib results and prediction of clinical outcome with FDG-PET/CT. Target Oncol 9(4):339-347
-
(2014)
Target Oncol
, vol.9
, Issue.4
, pp. 339-347
-
-
Boers-Sonderen, M.J.1
Geus-Oei, L.F.2
Desar, I.M.E.3
Van Der Graaf, W.T.A.4
Oyen, W.J.G.5
-
76
-
-
84896393304
-
Temsirolimus with or without megestrol acetate and tamoxifen for endometrial cancer: A gynecologic oncology group study
-
1:CAS:528:DC%2BC2cXhvVajtbo%3D
-
Fleming GF, Filiaci VL, Marzullo B, Zaino RJ, Davidson AS, Pearl M (2014) Temsirolimus with or without megestrol acetate and tamoxifen for endometrial cancer: a gynecologic oncology group study. Gynec Oncol 132:585-592
-
(2014)
Gynec Oncol
, vol.132
, pp. 585-592
-
-
Fleming, G.F.1
Filiaci, V.L.2
Marzullo, B.3
Zaino, R.J.4
Davidson, A.S.5
Pearl, M.6
-
77
-
-
37149010753
-
A phase II trial of the mTOR inhibitor AP23573 as a single agent in advanced endometrial cancer
-
Colombo N, McMeekin S, Schwartz P et al (2007) A phase II trial of the mTOR inhibitor AP23573 as a single agent in advanced endometrial cancer. J Clin Oncol 25:5516
-
(2007)
J Clin Oncol
, vol.25
, pp. 5516
-
-
Colombo, N.1
McMeekin, S.2
Schwartz, P.3
-
78
-
-
84913606847
-
Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer
-
1:CAS:528:DC%2BC2cXhsVOhtrzN 25173583
-
Tsoref D, Welch S, Lau S, Biagi J, Tonkin K, Lee Ann Martin LA (2014) Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer. Gynecol Oncol 135(2):184-189
-
(2014)
Gynecol Oncol
, vol.135
, Issue.2
, pp. 184-189
-
-
Tsoref, D.1
Welch, S.2
Lau, S.3
Biagi, J.4
Tonkin, K.5
Lee Ann Martin, L.A.6
-
79
-
-
77955770568
-
Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells
-
1:CAS:528:DC%2BC3cXoslekt7k%3D 20135346
-
Zakikhani M, Blouin MJ, Piura E, Pollak MN (2010) Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells. Breast Cancer Res Treat 123(1):271-279
-
(2010)
Breast Cancer Res Treat
, vol.123
, Issue.1
, pp. 271-279
-
-
Zakikhani, M.1
Blouin, M.J.2
Piura, E.3
Pollak, M.N.4
-
80
-
-
84894041491
-
Metformin is associated with improved survival in endometrial cancer
-
1:CAS:528:DC%2BC2cXivVOmtQ%3D%3D 24269517
-
Ko EM, Walter P, Jackson A, Clarkd L, Franasiak J et al (2014) Metformin is associated with improved survival in endometrial cancer. Gynecol Oncol 132:438-442
-
(2014)
Gynecol Oncol
, vol.132
, pp. 438-442
-
-
Ko, E.M.1
Walter, P.2
Jackson, A.3
Clarkd, L.4
Franasiak, J.5
-
81
-
-
84934450530
-
A phase II, single-arm study of RAD001 (Everolimus), Letrozole, and Metformin in patients with advanced or recurrent endometrial carcinoma
-
M.D. Anderson Cancer Center Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT01797523
-
M.D. Anderson Cancer Center (2000) A phase II, single-arm study of RAD001 (Everolimus), Letrozole, and Metformin in patients with advanced or recurrent endometrial carcinoma. In: ClinicalTrials.gov [internet]. Bethesda (MD): National Library of Medicine (US). https://clinicaltrials.gov/ct2/show/study/NCT01797523 NLM identifier: NCT01797523
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
82
-
-
84934450531
-
Paclitaxel and carboplatin with or without metformin hydrochloride in treating patients with stage III, IV, or Recurrent Endometrial Cancer
-
Gynecologic Oncology Group Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT02065687
-
Gynecologic Oncology Group (2000) Paclitaxel and carboplatin with or without metformin hydrochloride in treating patients with stage III, IV, or Recurrent Endometrial Cancer. In: ClinicalTrials.gov [internet]. Bethesda (MD): National Library of Medicine (US). https://clinicaltrials.gov/ct2/show/study/NCT02065687 NLM identifier: NCT02065687
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
83
-
-
84934450532
-
BKM120 as second-line therapy for advanced endometrial cancer
-
Novartis Pharmaceuticals Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT 01289041
-
Novartis Pharmaceuticals (2000) BKM120 as second-line therapy for advanced endometrial cancer. In: ClinicalTrials.gov [internet]. Bethesda (MD): National Library of Medicine (US). http://clinicaltrials.gov/show/NCT01289041 NLM identifier: NCT 01289041
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
84
-
-
84934450533
-
Study of XL147 (SAR245408) in Advanced or recurrent endometrial cancer
-
Sanofi Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT 01013324
-
Sanofi (2000) Study of XL147 (SAR245408) in Advanced or recurrent endometrial cancer. In: ClinicalTrials.gov [internet]. Bethesda (MD): National Library of Medicine (US). http://clinicaltrials.gov/show/NCT01013324 NLM identifier: NCT 01013324
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
85
-
-
84923108243
-
Phase II study of the PI3K inhibitor pilaralisib (SAR245408; XL147) in patients with advanced or recurrent endometrial carcinoma
-
Ursula M, Ignace V, Floor B, Lainie PM, Scott M, Michael B, Frank C, Yi X, Coumaran E, Sharad G (2014) Phase II study of the PI3K inhibitor pilaralisib (SAR245408; XL147) in patients with advanced or recurrent endometrial carcinoma. Gynecol Oncol. doi: 10.1016/j.ygyno.2014.12.019
-
(2014)
Gynecol Oncol
-
-
Ursula, M.1
Ignace, V.2
Floor, B.3
Lainie, P.M.4
Scott, M.5
Michael, B.6
Frank, C.7
Yi, X.8
Coumaran, E.9
Sharad, G.10
-
86
-
-
84934450535
-
Akt Inhibitor MK2206 in treating patients with recurrent or advanced endometrial cancer
-
National Cancer Institute Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT 01307631
-
National Cancer Institute (2000) Akt Inhibitor MK2206 in treating patients with recurrent or advanced endometrial cancer. In: ClinicalTrials.gov [internet]. Bethesda (MD): National Library of Medicine (US). http://clinicaltrials.gov/show/NCT01307631 NLM identifier: NCT 01307631
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
87
-
-
84877679916
-
Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells
-
1:CAS:528:DC%2BC3sXntlSis70%3D 23443805
-
Konecny GE, Kolarova T, O'Brien NA, Winterhoff B, Yang G et al (2013) Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells. Mol Cancer Ther 12(5):632-642
-
(2013)
Mol Cancer Ther
, vol.12
, Issue.5
, pp. 632-642
-
-
Konecny, G.E.1
Kolarova, T.2
O'Brien, N.A.3
Winterhoff, B.4
Yang, G.5
-
88
-
-
84877928037
-
Combined targeting of FGFR2 and mTOR by ponatinib and ridaforolimus results in synergistic antitumor activity in FGFR2 mutant endometrial cancer models
-
1:CAS:528:DC%2BC3sXmvVemsLY%3D 23468082
-
Gozgit JM, Squillace RM, Wongchenko MJ, Miller D et al (2013) Combined targeting of FGFR2 and mTOR by ponatinib and ridaforolimus results in synergistic antitumor activity in FGFR2 mutant endometrial cancer models. Cancer Chemother Pharmacol 71:1315-1323
-
(2013)
Cancer Chemother Pharmacol
, vol.71
, pp. 1315-1323
-
-
Gozgit, J.M.1
Squillace, R.M.2
Wongchenko, M.J.3
Miller, D.4
-
90
-
-
84908030997
-
A phase II trial of brivanib in recurrent or persistent endometrial cancer: An NRG Oncology/Gynecologic Oncology Group Study
-
1:CAS:528:DC%2BC2cXhtlSqs7fE 4278402 25019571
-
Powell MA, Sill MW, Goodfellow PJ, Benbrook DM, Lankes HA, Leslie KK et al (2014) A phase II trial of brivanib in recurrent or persistent endometrial cancer: an NRG Oncology/Gynecologic Oncology Group Study. Gynecol Oncol 135:38-43
-
(2014)
Gynecol Oncol
, vol.135
, pp. 38-43
-
-
Powell, M.A.1
Sill, M.W.2
Goodfellow, P.J.3
Benbrook, D.M.4
Lankes, H.A.5
Leslie, K.K.6
-
91
-
-
84920741562
-
A phase II evaluation of nintedanib (BIBF-1120) in the treatment of recurrent or persistent endometrial cancer: An NRG Oncology/Gynecologic Oncology Group Study
-
1:CAS:528:DC%2BC2cXhslGrsL%2FN
-
Dizon DS, Michael Sill MW, Schilder JM, McGonigle KF, Rahman Z et al (2014) A phase II evaluation of nintedanib (BIBF-1120) in the treatment of recurrent or persistent endometrial cancer: an NRG Oncology/Gynecologic Oncology Group Study. Gynec Oncol 135:441-445
-
(2014)
Gynec Oncol
, vol.135
, pp. 441-445
-
-
Dizon, D.S.1
Michael, S.M.2
Schilder, J.M.3
McGonigle, K.F.4
Rahman, Z.5
-
92
-
-
83355163329
-
GDC-0980 is a novel class i PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway
-
1:CAS:528:DC%2BC3MXhsFylurfJ 21998291
-
Wallin JJ, Edgar KA, Guan J, Berry M, PriorWW Lee L et al (2011) GDC-0980 is a novel class I PI3K/mTOR kinase inhibitor with robust activity in cancer models driven by the PI3K pathway. Mol Cancer Ther 10:2426-2436
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 2426-2436
-
-
Wallin, J.J.1
Edgar, K.A.2
Guan, J.3
Berry, M.4
Priorww, L.L.5
-
93
-
-
51049109033
-
Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
-
1:CAS:528:DC%2BD1cXoslCgtb4%3D 18606717
-
Maira SM, Stauffer F, Brueggen J, Furet P, Schnell C, Fritsch C et al (2008) Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Mol Cancer Ther 7:1851-1863
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1851-1863
-
-
Maira, S.M.1
Stauffer, F.2
Brueggen, J.3
Furet, P.4
Schnell, C.5
Fritsch, C.6
-
94
-
-
80054764153
-
Activity of dual PI3K/mTOR inhibitor, NVP-BEZ235, and mTOR inhibitor, RAD001 (everolimus), in endometrial cancer cell lines [abstract]
-
(supp abstr 5074)
-
Shoji K, Oda K, Nakagawa S, Ikeda Y, Kuramoto H, Nishida M et al (2010) Activity of dual PI3K/mTOR inhibitor, NVP-BEZ235, and mTOR inhibitor, RAD001 (everolimus), in endometrial cancer cell lines [abstract]. J Clin Oncol 28:15s (supp abstr 5074)
-
(2010)
J Clin Oncol
, vol.28
, pp. 15s
-
-
Shoji, K.1
Oda, K.2
Nakagawa, S.3
Ikeda, Y.4
Kuramoto, H.5
Nishida, M.6
-
95
-
-
84934450536
-
A study of GDC-0980 in the treatment of recurrent or persistent endometrial carcinoma
-
Genentech, Inc. Bethesda (MD): National Library of Medicine (US) NLM identifier: NCT01455493
-
Genentech, Inc. (2000) A study of GDC-0980 in the treatment of recurrent or persistent endometrial carcinoma. In: ClinicalTrials.gov [internet]. Bethesda (MD): National Library of Medicine (US). http://clinicaltrials.gov/show/NCT01455493 NLM identifier: NCT01455493
-
(2000)
ClinicalTrials.gov [Internet]
-
-
-
96
-
-
0021281767
-
Treatment of recurrent endometrial adenocarcinoma with a combination of doxorubicin and cisplatin
-
1:STN:280:DyaL2c3ivVKnsg%3D%3D 6539567
-
Trope C, Johnsson JE, Simonsen E, Christiansen H, Cavallin-Stahl E, Horvath G (1984) Treatment of recurrent endometrial adenocarcinoma with a combination of doxorubicin and cisplatin. Am J Obstet Gynecol 149:379-381
-
(1984)
Am J Obstet Gynecol
, vol.149
, pp. 379-381
-
-
Trope, C.1
Johnsson, J.E.2
Simonsen, E.3
Christiansen, H.4
Cavallin-Stahl, E.5
Horvath, G.6
-
97
-
-
0037352608
-
Doxorubicin versus doxorubicin and cisplatin in endometrial carcinoma: Definitive results of a randomised study (55872) by the EORTC Gynaecological Cancer Group
-
12598351
-
Van Wijk FH, Aapro MS, van Wijk FH, Bolis G et al (2003) Doxorubicin versus doxorubicin and cisplatin in endometrial carcinoma: definitive results of a randomised study (55872) by the EORTC Gynaecological Cancer Group. Ann Oncol 14:441-448
-
(2003)
Ann Oncol
, vol.14
, pp. 441-448
-
-
Van Wijk, F.H.1
Aapro, M.S.2
Van Wijk, F.H.3
Bolis, G.4
|