Microsatellite instability: Impact on cancer progression in proximal and distal colorectal cancers

European Journal of Cancer

Volumn 35, Issue 2, 1999, Pages 197-201

  Jernvall, P ^a,b   Makinen M J ^a   Karttunen, T J ^a   Makela J ^a   Vihko, P ^a  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Colorectal cancer; Microsatellite instability; Prognosis; Replication errors; RER; Survival

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER GENETICS; CANCER GROWTH; CANCER SURVIVAL; CHILD; COLORECTAL CANCER; DNA REPLICATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR LOCALIZATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; CHILD; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; FEMALE; FOLLOW-UP STUDIES; GENES, MCC; GENETIC MARKERS; HUMANS; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; PROGNOSIS; RECTAL NEOPLASMS; SURVIVAL ANALYSIS;

EID: 0033083214     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00306-2     Document Type: Article

References (43)

1. Risinger J.I., Berchuck A., Kohler M.F., Watson P., Lynch H.T., Boyd J. Genetic instability of microsatellites in endometrial carcinoma. Cancer Res. 53:1993;5100-5103.
2. Han H-J., Yanagisawa A., Kato Y., Park J-G., Nakamura Y. Genetic instability in pancreatic cancer and poorly differentiated type of gastric cancer. Cancer Res. 53:1993;5087-5089.
3. Aaltonen L.A., Peltomäki P., Leach F.S., et al. Clues to the pathogenesis of familial colorectal cancer. Science. 260:1993;812-816.
4. Ionov Y., Peinado M.A., Malkhosyan S., Shibata D., Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature. 363:1993;558-561.
5. Kim H., Jen J., Vogelstein B., Hamilton S.R. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol. 145:1994;148-156.
6. Konishi M., Kikuchi-Yanoshita R., Tanaka K., et al. Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis and sporadic colon cancer. Gastroenterology. 111:1996;307-317.
7. Liu B., Parsons R., Papadopoulos N., et al. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Med. 2:1996;169-174.
8. Leach F.S., Nicolaides N.C., Papadopoulos N., et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell. 75:1993;1215-1225.
9. Papadopoulos N., Nicolaides N.C., Wei Y-F., et al. Mutation of a mutL homolog in hereditary colon cancer. Science. 263:1994;1625-1629.
10. Nicolaides N.C., Papadopoulos N., Liu B., et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 371:1994;75-80.
11. Nyström-Lahti M., Parsons R., Sistonen P., et al. Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage. Am J Hum Genet. 55:1994;659-665.
12. Hemminki A., Peltomäki P., Mecklin J-P., et al. Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nature Genet. 8:1994;405-410.
13. Thibodeau S.N., French A.J., Roche P.C., et al. Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res. 56:1996;4836-4840.
14. Liu B., Nicolaides N.C., Markowitz S., et al. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability. Nature Genet. 9:1995;48-55.
15. Liu B., Farrington S.M., Petersen G.M., et al. Genetic instability in the majority of young patients with colorectal cancer. Nature Med. 1:1995;348-352.
16. Wijnen J., Khan P.M., Vasen H., et al. Hereditary nonpolyposis colorectal cancer families not complying with the Amsterdam criteria show extremely low frequency of mismatch-repair-gene mutations. Am J Hum Genet. 61:1997;329-335.
17. Dietmeier W., Wallinger S., Bocker T., Kullmann F., Fishel R., Rüschkoff J. Diagnostic microsatellite instability: definition and correlation with mismatch repair protein expression. Cancer Res. 57:1997;4749-4756.
18. Eshleman J.R., Lang E.Z., Bowerfind G.K., et al. Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer. Oncogene. 10:1995;33-37.
19. Kane M.F., Loda M., Gaida G.M., et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 57:1997;808-811.
20. Thibodeau S.N., Bren G., Schaid D. Microsatellite instability in cancer of proximal colon. Science. 260:1993;816-818.
21. Lothe R.A., Peltomäki P., Meling G.I., et al. Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history. Cancer Res. 53:1993;5849-5852.
22. Risio M., Reato G., Di Celle P.F., Fizzotti M., Rossini F.P., Foa R. Microsatellite instability is associated with the histological features of the tumor in nonfamilial colorectal cancer. Cancer Res. 56:1996;5470-5474.
23. Jass JR, Sobin LH. Histological typing of intestinal tumors. World Health Organization. International Classification of Tumors. 2nd ed. Berlin, Springer, 1989.
24. Turnbull R.B., Kyle K., Watson F.R., Spratt J. Cancer of colon: the influence of the no-touch isolation technique on survival rates. Ann Surg. 166:1967;420-427.
25. Ponz de Leon M., Sant M., Micheli A., et al. Clinical and pathological prognostic indicators in colorectal cancer. Cancer. 69:1992;626-635.
26. Jernvall P., Mäkinen M., Karttunen T., Mäkelä J., Vihko P. Conserved region mutations of the p53 gene are concentrated in distal colorectal cancers. Int J Cancer (Pred Oncol). 74:1997;97-101.
27. Elo J.P., Kvist L., Leinonen K., et al. Mutated human androgen-receptor gene detected in a prostatic-cancer patient is also activated by estradiol. J Clin Endocrinol Metab. 80:1995;3494-3500.
28. Wright DK, Manos MM. Sample preparation from paraffin-embedded tissues. In Innis MA, Gelfand DH, Sninsky JJ, White TJ, eds. PCR Protocols: A Guide to Methods and Applications. San Diego, Academic Press, 1990, 153-158.
29. Dib C., Faure S., Fizames C., et al. A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature. 380:1996;152-154.
30. Graham D.M., Appelman H.D. Crohn's-like lymphoid reaction and colorectal carcinoma: a potential histologic prognosticator. Modern Pathology. 3:1990;332-335.
31. Shibata D., Peinado M.A., Ionov Y., Malkhosyan S., Perucho M. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis, that persists after transformation. Nature Genet. 6:1994;273-281.
32. Markowitz S., Wang J., Myeroff L., et al. Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science. 268:1995;1336-1338.
33. Rampino N., Yamamoto H., Ionov Y., et al. Somatic frameshift mutations in the BAX gene in colon cancers of microsatellite mutator phenotype. Science. 275:1997;967-969.
34. Souza R.F., Appel R., Yin J., et al. Microsatellite instability in the insulin-like growth factor II receptor gene in gastrointestinal tumours. Nature Genet. 14:1996;255-257.
35. Bicknell D.C., Kaklamanis L., Hampson R., Bodmer W.F., Karran P. Selection for β2-microglobulin mutation in mismatch repair-defective colorectal carcinomas. Curr Biol. 6:1996;1695-1697.
36. Malkhosyan S., Rampino N., Yamamoto H., Perucho M. Frameshift mutator mutations. Nature. 382:1996;499-500.
37. Delattre O., Law D.J., Remvikos Y., et al. Multiple genetic alterations in distal and proximal colorectal cancer. Lancet. 12:1989;353-355.
38. Bufill J.A. Colorectal cancer: evidence for distinct genetic categories based on proximal or distal tumor location. Ann Int Med. 113:1990;779-788.
39. Wynder E.L., Reddy B.S., Weisburger J.H. Environmental dietary factors in colorectal cancer. Some unresolved issues. Cancer. 70:1992;1222-1228.
40. Kervinen K., Södervik H., Mäkelä J. Is the development of adenoma and carcinoma in proximal colon related to apolipoprotein E phenotype? Gastroenterology. 110:1996;1785-1790.
41. Breivik J., Lothe R.A., Meling G.I., Rognum T.O., Børresen-Dale A-L., Gaudernack G. Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors. Int J Cancer. 74:1997;664-669.
42. Böttger T.C., Potrazt D., Stöckle M., Wellek S., Klupp J., Junginger T. Prognostic value of DNA analysis in colorectal carcinoma. Cancer. 72:1993;3579-3587.
43. Tang R., Ho Y-S., You Y.T., et al. Prognostic evaluation of DNA flow cytometric and histopathologic parameters of colorectal cancer. Cancer. 76:1995;1724-1730.