Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response

EMBO Molecular Medicine

Volumn 7, Issue 7, 2015, Pages 973-988

  Sartorius, Rossella ^a   D'Apice, Luciana ^a   Trovato, Maria ^a   Cuccaro, Fausta ^a   Costa, Valerio ^b   De Leo, Maria Giovanna ^c   Marzullo, Vincenzo Manuel ^a,c   Biondo, Carmelo ^d   D'Auria, Sabato ^a,e   De Matteis, Maria Antonietta ^c   Ciccodicola, Alfredo ^b,f   De Berardinis, Piergiuseppe ^a  

^a INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

^b INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^c TELETHON INSTITUTE OF GENETICS AND MEDICINE TIGEM   (Italy)

^d UNIVERSITY OF MESSINA   (Italy)

^e CNR   (Italy)

^f UNIVERSITY OF NAPLES PARTHENOPE   (Italy)

Author keywords

Antigen delivery; DEC 205; Dendritic cells; Filamentous bacteriophage; TLR9

Indexed keywords

ANTIGEN; CELL SURFACE RECEPTOR; DEC-205 RECEPTOR; DRUG CARRIER; IMMUNOLOGICAL ADJUVANT; LECTIN; LEUKOCYTE ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; TLR9 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 9;

ANIMAL; C57BL MOUSE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL SURFACE DISPLAY; DENDRITIC CELL; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; INOVIRUS; METABOLISM;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS; ANTIGENS, CD; CD8-POSITIVE T-LYMPHOCYTES; CELL SURFACE DISPLAY TECHNIQUES; CELLS, CULTURED; DENDRITIC CELLS; DRUG CARRIERS; GENE EXPRESSION PROFILING; IMMUNITY, INNATE; INOVIRUS; LECTINS, C-TYPE; MICE, INBRED C57BL; MINOR HISTOCOMPATIBILITY ANTIGENS; RECEPTORS, CELL SURFACE; SINGLE-CHAIN ANTIBODIES; TOLL-LIKE RECEPTOR 9;

EID: 84934437965     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201404525     Document Type: Article

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