Vaccination with filamentous bacteriophages targeting DEC-205 induces DC maturation and potent anti-tumor T-cell responses in the absence of adjuvants

European Journal of Immunology

Volumn 41, Issue 9, 2011, Pages 2573-2584

  Sartorius, Rossella ^a   Bettua, Clotilde ^a   D'Apice, Luciana ^a   Caivano, Antonella ^a,d   Trovato, Maria ^a   Russo, Domenico ^a   Zanoni, Ivan ^b   Granucci, Francesca ^b   Mascolo, Dina ^c   Barba, Pasquale ^c   Pozzo, Giovanna Del ^c   de Berardinis, Piergiuseppe ^a  

^a INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c INSTITUTE OF GENETICS AND BIOPHYSICS ADRIANO BUZZATI TRAVERSO   (Italy)

^d REFERRAL CANCER CENTER OF BASILICATA   (Italy)

Author keywords

CD8 + T cells; DEC 205; Dendritic cells; Filamentous bacteriophage fd; Vaccination

Indexed keywords

ALPHA INTERFERON; CELL SURFACE PROTEIN; COAT PROTEIN; COAT PROTEIN PIII; DENDRITIC CELL VACCINE; INTERLEUKIN 6; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY DEC205; OVALBUMIN; PEPTIDE; PROTEIN DEC205; SERYLISOLEUCYLISOLEUCYLASPARAGINYLPHENYLALANYLGLUTAMYLLYSYLLEUCINE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIOPHAGE; CD8+ T LYMPHOCYTE; CELL MATURATION; CONTROLLED STUDY; DENDRITIC CELL; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG TARGETING; FEMALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TUMOR; VACCINATION;

ANIMALS; ANTIGENS, CD; CANCER VACCINES; CAPSID PROTEINS; CELL DIFFERENTIATION; DENDRITIC CELLS; ENTEROBACTERIACEAE; INOVIRUS; INTERFERON-GAMMA; INTERLEUKIN-6; LECTINS, C-TYPE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MOLECULAR TARGETED THERAPY; OVALBUMIN; PEPTIDE FRAGMENTS; RECEPTORS, CELL SURFACE; SINGLE-CHAIN ANTIBODIES; TRANSGENES; TUMOR BURDEN; VACCINATION; VIRION;

EID: 80052173860     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141526     Document Type: Article

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