TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways

Journal of Leukocyte Biology

Volumn 96, Issue 1, 2014, Pages 93-103

  Xu, Jun ^a   Zoltick, Philip W ^b   Gamero, Ana M ^a   Gallucci, Stefania ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Autoimmunity; Immune activation; Viral infection

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; EXONUCLEASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; LENTIVIRUS VECTOR; LIGAND; STAT1 PROTEIN; STAT2 PROTEIN; TOLL LIKE RECEPTOR 3 LIGAND; TOLL LIKE RECEPTOR 4 LIGAND; TOLL LIKE RECEPTOR 7 LIGAND; TOLL LIKE RECEPTOR 9 LIGAND; TOLL LIKE RECEPTOR LIGAND; TREX1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CYTOKINE PRODUCTION; CYTOPLASM; DENDRITIC CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPLEEN; UPREGULATION; VIRAL GENE THERAPY; WESTERN BLOTTING;

AUTOIMMUNITY; IMMUNE ACTIVATION; VIRAL INFECTION;

ANIMALS; AUTOCRINE COMMUNICATION; DENDRITIC CELLS; EXODEOXYRIBONUCLEASES; GENETIC THERAPY; GENETIC VECTORS; HIV INFECTIONS; HIV-1; INTERFERON-BETA; LIGANDS; MICE; MICE, KNOCKOUT; NF-KAPPA B; PHOSPHOPROTEINS; SIGNAL TRANSDUCTION; SPLEEN; STAT1 TRANSCRIPTION FACTOR; STAT2 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTORS; UP-REGULATION;

EID: 84903512661     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.2A0713-393RR     Document Type: Article

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