Protective role of naringin against cisplatin induced oxidative stress, inflammatory response and apoptosis in rat striatum via suppressing ROS-mediated NF-κB and P53 signaling pathways

Chemico-Biological Interactions

Volumn 239, Issue , 2015, Pages 76-86

  Chtourou, Yassine ^a   Aouey, Bakhta ^a   Kebieche, Mohammed ^b   Fetoui, Hamadi ^a  

^a University of Sfax   (Tunisia)

^b UNIVERSITY OF JIJEL   (Algeria)

Author keywords

Aged rat; Chemotherapy; Inflammation; Oxidative stress; P53 expression; Striatum

Indexed keywords

AURANTIIN; CARBONYL DERIVATIVE; CATALASE; CISPLATIN; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; MESSENGER RNA; NITRITE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; ENZYME; FLAVANONE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; CORPUS STRIATUM; DETERIORATION; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; INFLAMMATION; MIDDLE AGED; NEUROPROTECTION; NEUROTOXICITY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION; AGE; ANIMAL; CHEMICALLY INDUCED; DNA FRAGMENTATION; DRUG EFFECTS; ENCEPHALITIS; GENETICS; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALIA; RATTUS;

AGE FACTORS; ANIMALS; ANTIOXIDANTS; CISPLATIN; CORPUS STRIATUM; DNA FRAGMENTATION; ENCEPHALITIS; ENZYMES; FLAVANONES; NF-KAPPA B; NITRITES; OXIDATIVE STRESS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84933574176     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.06.036     Document Type: Article

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