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Volumn 13, Issue 4, 2010, Pages 976-984

Protective effect of naringin, a citrus flavonoid, against colchicine-induced cognitive dysfunction and oxidative damage in rats

Author keywords

Alzheimer's disease; colchicine; naringin; neuroprotective; oxidative stress

Indexed keywords

ACETYLCHOLINESTERASE; AURANTIIN; CATALASE; COLCHICINE; GENTAMICIN; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; NITRITE; SUPEROXIDE DISMUTASE;

EID: 77955217138     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2009.1251     Document Type: Article
Times cited : (84)

References (58)
  • 1
    • 0021207461 scopus 로고
    • Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
    • Glenner GG, Wong CW: Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun 1984;122:1131-1135.
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1131-1135
    • Glenner, G.G.1    Wong, C.W.2
  • 2
    • 20444399515 scopus 로고    scopus 로고
    • Stress in the brain: Novel cellular mechanisms of injury linked to Alzheimer's disease
    • Zhao ZC, Li F, Maiese K: Stress in the brain: novel cellular mechanisms of injury linked to Alzheimer's disease. Brain Res Brain Res Rev 2005;49:1-21.
    • (2005) Brain Res Brain Res Rev , vol.49 , pp. 1-21
    • Zhao, Z.C.1    Li, F.2    Maiese, K.3
  • 3
    • 0142042435 scopus 로고    scopus 로고
    • Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: Potential strategies for neuro-protection
    • Chen GJ, Xu J, Lahousse SA, Caggiano NL, De la SM: Transient hypoxia causes Alzheimer-type molecular and biochemical abnormalities in cortical neurons: potential strategies for neuro-protection. J Alzheimers Dis 2003;5:209-228.
    • (2003) J Alzheimers Dis , vol.5 , pp. 209-228
    • Chen, G.J.1    Xu, J.2    Lahousse, S.A.3    Caggiano, N.L.4    De La, S.M.5
  • 4
    • 0037456671 scopus 로고    scopus 로고
    • Anti-apoptotic proteins are oxidized by Abeta 25-35 in Alzheimer's fibroblasts
    • Choi J, Malakowsky CA, Talent JM, et al.: Anti-apoptotic proteins are oxidized by Abeta 25-35 in Alzheimer's fibroblasts. Biochim Biophys Acta 2003;1637:135-141.
    • (2003) Biochim Biophys Acta , vol.1637 , pp. 135-141
    • Choi, J.1    Malakowsky, C.A.2    Talent, J.M.3
  • 5
    • 0036753272 scopus 로고    scopus 로고
    • Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death
    • Butterfield DA, Castegna A, Lauderback CM, Drake J: Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death. Neurobiol Aging 2002;23:655-664.
    • (2002) Neurobiol Aging , vol.23 , pp. 655-664
    • Butterfield, D.A.1    Castegna, A.2    Lauderback, C.M.3    Drake, J.4
  • 6
    • 0032933750 scopus 로고    scopus 로고
    • Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF
    • Lovell MA, Gabbita SP, Markesbery WR: Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF. J Neurochem 1999;72:771-776.
    • (1999) J Neurochem , vol.72 , pp. 771-776
    • Lovell, M.A.1    Gabbita, S.P.2    Markesbery, W.R.3
  • 7
    • 0036344646 scopus 로고    scopus 로고
    • Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats
    • Kumar MHV, Gupta YK: Intracerebroventricular administration of colchicine produces cognitive impairment associated with oxidative stress in rats. Pharmacol Biochem Behav 2002;73:565-571.
    • (2002) Pharmacol Biochem Behav , vol.73 , pp. 565-571
    • Kumar, M.H.V.1    Gupta, Y.K.2
  • 8
    • 33645101470 scopus 로고    scopus 로고
    • A role of mixed lineage kinases in granule cell apoptosis induced cytoskeletal disruption
    • Muller GJ, Geist MA, Veng LM, et al.: A role of mixed lineage kinases in granule cell apoptosis induced cytoskeletal disruption. J Neurochem 2006;96:1242-1252.
    • (2006) J Neurochem , vol.96 , pp. 1242-1252
    • Muller, G.J.1    Geist, M.A.2    Veng, L.M.3
  • 9
    • 0000397413 scopus 로고
    • Effects of drugs upon axoplasmic transport
    • McClure WO: Effects of drugs upon axoplasmic transport. Adv Chemother Pharmacol 1972;10:185-220.
    • (1972) Adv Chemother Pharmacol , vol.10 , pp. 185-220
    • McClure, W.O.1
  • 10
    • 0345276565 scopus 로고    scopus 로고
    • Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
    • Mandelkow EM, Stamer K, Vogel R, Theis E, Mandelkow E: Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 2003;24:1079-1085.
    • (2003) Neurobiol Aging , vol.24 , pp. 1079-1085
    • Mandelkow, E.M.1    Stamer, K.2    Vogel, R.3    Theis, E.4    Mandelkow, E.5
  • 11
    • 0025349056 scopus 로고
    • Cholinergic cell loss and cognitive impairments following intracerebroventricular or intradentate injection of colchicine
    • Emerich DF, Walsh TJ: Cholinergic cell loss and cognitive impairments following intracerebroventricular or intradentate injection of colchicine. Brain Res 1990;517:157-167.
    • (1990) Brain Res , vol.517 , pp. 157-167
    • Emerich, D.F.1    Walsh, T.J.2
  • 12
    • 77955202727 scopus 로고    scopus 로고
    • Neuroprotective effects of Cen-tella asiatica against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress
    • doi:10.4061=2009=972178
    • Kumar A, Dogra S, Prakash A: Neuroprotective effects of Cen-tella asiatica against intracerebroventricular colchicine-induced cognitive impairment and oxidative stress. Int J Alzheimers Dis 2009 doi:10.4061=2009=972178.
    • (2009) Int J Alzheimers Dis
    • Kumar, A.1    Dogra, S.2    Prakash, A.3
  • 13
    • 58549087534 scopus 로고    scopus 로고
    • Neuroprotective effect of carvedilol, an ad-renergic antagonist against colchicine induced cognitive impairment and oxidative damage in rat
    • Kumar A, Dogra S: Neuroprotective effect of carvedilol, an ad-renergic antagonist against colchicine induced cognitive impairment and oxidative damage in rat. Pharmacol Biochem Behav 2009;92:25-31.
    • (2009) Pharmacol Biochem Behav , vol.92 , pp. 25-31
    • Kumar, A.1    Dogra, S.2
  • 14
    • 34548142159 scopus 로고    scopus 로고
    • Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type
    • Kumar A, Naidu PS, Sehgal N, Padi SSV, Goyal R: Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type. Pharmacol Rep 2007;59:274-283.
    • (2007) Pharmacol Rep , vol.59 , pp. 274-283
    • Kumar, A.1    Naidu, P.S.2    Sehgal, N.3    Padi, S.S.V.4    Goyal, R.5
  • 15
    • 34848840946 scopus 로고    scopus 로고
    • Effect of curcumin on intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats
    • DOI 10.1089/jmf.2006.076
    • Kumar A, Naidu PS, Sehgal N, Padi SSV: Effect of curcumin on intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. J Med Food 2007;10:486-494. (Pubitemid 47493496)
    • (2007) Journal of Medicinal Food , vol.10 , Issue.3 , pp. 486-494
    • Kumar, A.1    Naidu, P.S.2    Seghal, N.3    Padi, S.S.V.4
  • 18
    • 0029965264 scopus 로고    scopus 로고
    • Flavonoids of rare Artemisia species and their antifungal properties
    • Swiader KE, Lamer-Zarawaska E: Flavonoids of rare Artemisia species and their antifungal properties. Fitoterapia 1996;67: 77-79.
    • (1996) Fitoterapia , vol.67 , pp. 77-79
    • Swiader, K.E.1    Lamer-Zarawaska, E.2
  • 19
    • 0020628197 scopus 로고
    • Interactions of metal complexing compounds with lymphocytes and lymphoid cell lines
    • Jung G, Hennings G, Pfeifer M, Bessler WG: Interactions of metal complexing compounds with lymphocytes and lymphoid cell lines. Mol Pharmacol 1983;23:698-702.
    • (1983) Mol Pharmacol , vol.23 , pp. 698-702
    • Jung, G.1    Hennings, G.2    Pfeifer, M.3    Bessler, W.G.4
  • 20
    • 4544360864 scopus 로고    scopus 로고
    • Antihypercholesterolaemic property of naringin alters plasma and tissue lipids, cholesterol regulating enzymes, fecal sterol and tissue morphology in rabbits
    • Jeon SM, Park YB, Choi MS: Antihypercholesterolaemic property of naringin alters plasma and tissue lipids, cholesterol regulating enzymes, fecal sterol and tissue morphology in rabbits. Clin Nutr 2004;23:1025-1034.
    • (2004) Clin Nutr , vol.23 , pp. 1025-1034
    • Jeon, S.M.1    Park, Y.B.2    Choi, M.S.3
  • 21
    • 20344377141 scopus 로고    scopus 로고
    • Modulation of radiation induced alteration in the antioxidant status of mice by naringin
    • Jagetia GC, Reddy TK: Modulation of radiation induced alteration in the antioxidant status of mice by naringin. Life Sci 2005;77:780-794.
    • (2005) Life Sci , vol.77 , pp. 780-794
    • Jagetia, G.C.1    Reddy, T.K.2
  • 22
    • 67651099137 scopus 로고    scopus 로고
    • Protective effect of naringin against ischemic reperfusion cerebral injury: Possible neurobe-havioral, biochemical and cellular alterations in rat brain
    • Gaur V, Aggarwal A, Kumar A: Protective effect of naringin against ischemic reperfusion cerebral injury: possible neurobe-havioral, biochemical and cellular alterations in rat brain. Eur J Pharmacol 2009;616:147-154.
    • (2009) Eur J Pharmacol , vol.616 , pp. 147-154
    • Gaur, V.1    Aggarwal, A.2    Kumar, A.3
  • 23
    • 0028973416 scopus 로고
    • The fate of naringin in humans: A key to grape fruit juice drug-interactions
    • Fuhr U, Kummert AL: The fate of naringin in humans: a key to grape fruit juice drug-interactions. Clin Pharmacol Ther 1995; 58:365-373.
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 365-373
    • Fuhr, U.1    Kummert, A.L.2
  • 24
    • 25444508963 scopus 로고    scopus 로고
    • Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease
    • Zbarsky V, Datla KP, Parkar S, Rai DK, Aruoma OI, Dexter DT: Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease. Free Radic Res 2005; 39:1119-1125.
    • (2005) Free Radic Res , vol.39 , pp. 1119-1125
    • Zbarsky, V.1    Datla, K.P.2    Parkar, S.3    Rai, D.K.4    Aruoma, O.I.5    Dexter, D.T.6
  • 25
    • 0026541978 scopus 로고
    • Evaluation of learning and memory mechanisms employing plus maze in rats and mice
    • Sharma AC, Kulkarni SK: Evaluation of learning and memory mechanisms employing plus maze in rats and mice. Prog Neu-ropsychopharmacol Biol Psychiatry 1992;16:117-125.
    • (1992) Prog Neu-ropsychopharmacol Biol Psychiatry , vol.16 , pp. 117-125
    • Sharma, A.C.1    Kulkarni, S.K.2
  • 26
    • 0013914976 scopus 로고
    • Mechanism of lipid peroxide formation in animal tissues
    • Wills ED: Mechanism of lipid peroxide formation in animal tissues. Biochem J 1966;99:667-676.
    • (1966) Biochem J , vol.99 , pp. 667-676
    • Wills, E.D.1
  • 27
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman GL: Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 28
    • 58549096967 scopus 로고
    • 15N) nitrate in biological fluids
    • Green LC, Wagner DA, Glagowski J: Analysis of nitrate, nitrite and (15N) nitrate in biological fluids. J Biol Chem 1982;193:265-275.
    • (1982) J Biol Chem , vol.193 , pp. 265-275
    • Green, L.C.1    Wagner, D.A.2    Glagowski, J.3
  • 29
    • 0017804313 scopus 로고
    • Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay for superoxide dismutase
    • Kono Y: Generation of superoxide radical during auto-oxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys 1978;186:189-195.
    • (1978) Arch Biochem Biophys , vol.186 , pp. 189-195
    • Kono, Y.1
  • 30
    • 0002191974 scopus 로고
    • Catalase
    • (Berg-meyer HU ed.). Academic Press New York
    • Luck H: Catalase. In: Methods of Enzymatic Analysis (Berg-meyer HU, ed.). Academic Press, New York, 1971, pp. 885-893.
    • (1971) Methods of Enzymatic Analysis , pp. 885-893
    • Luck, H.1
  • 31
    • 0019741605 scopus 로고
    • Assays for differentiation of glutathi-one-S-transferases
    • Habig WH, Jakoby WB: Assays for differentiation of glutathi-one-S- transferases. Methods Enzymol 1981;77:398-405.
    • (1981) Methods Enzymol , vol.77 , pp. 398-405
    • Habig, W.H.1    Jakoby, W.B.2
  • 33
    • 29744466425 scopus 로고
    • Determination of serum proteins by means of biuret reaction
    • Gornall AG, Bardawill CT, David MM: Determination of serum proteins by means of biuret reaction. J Biol Chem 1949;177:751-766.
    • (1949) J Biol Chem , vol.177 , pp. 751-766
    • Gornall, A.G.1    Bardawill, C.T.2    David, M.M.3
  • 34
    • 34249027009 scopus 로고    scopus 로고
    • Connecting TNF - A signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: Relevance for the behavioral and synaptic deficits induced by amyloid-b protein
    • Medeiros R, Prediger RDS, Passos GF, Pandolfo P, Duarte FS, Franco JL: Connecting TNF-a signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid-b protein. J Neurosci 2007;27:5394-5404.
    • (2007) J Neurosci , vol.27 , pp. 5394-5404
    • Medeiros, R.1    Prediger, R.D.S.2    Passos, G.F.3    Pandolfo, P.4    Duarte, F.S.5    Franco, J.L.6
  • 35
    • 33750737492 scopus 로고    scopus 로고
    • Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: Biochemical and histopathological evidences
    • DOI 10.1016/j.tox.2006.09.005, PII S0300483X06005750
    • Rajadurai M, Prince PSM: Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxi-city in Wistar rats: biochemical and histopathological evidences. Toxicology 2006;228:259-268. (Pubitemid 44708452)
    • (2006) Toxicology , vol.228 , Issue.2-3 , pp. 259-268
    • Rajadurai, M.1    Prince, P.S.M.2
  • 36
    • 34147139570 scopus 로고    scopus 로고
    • Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits
    • Choi SY, Ko HC, Ko SY, et al.: Correlation between flavonoid content and the NO production inhibitory activity of peel extracts from various citrus fruits. Biol Pharm Bull 2007;30:772-778.
    • (2007) Biol Pharm Bull , vol.30 , pp. 772-778
    • Choi, S.Y.1    Ko, H.C.2    Ko, S.Y.3
  • 38
    • 0031057901 scopus 로고    scopus 로고
    • 36742 in mice
    • DOI 10.1016/S0006-8993(96)01158-4, PII S0006899396011584
    • Yu Z, Cheng G, Hu B: Mechanism of colchicine impairment on learning and memory, and protective effect of CGP36742 in mice. Brain Res 1997;750:53-58. (Pubitemid 27116248)
    • (1997) Brain Research , vol.750 , Issue.1-2 , pp. 53-58
    • Yu, Z.1    Cheng, G.2    Hu, B.3
  • 39
    • 0027364979 scopus 로고
    • NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C
    • Hammer B, Parker WD, Bennett JP: NMDA receptors increase OH radicals in vivo by using nitric oxide synthase and protein kinase C. Neuroreport 1993;5:72-74.
    • (1993) Neuroreport , vol.5 , pp. 72-74
    • Hammer, B.1    Parker, W.D.2    Bennett, J.P.3
  • 40
    • 0034661966 scopus 로고    scopus 로고
    • Differential effects of colchicine on the induction of nitric oxide synthase in neurons containing progesterone receptors of the guinea pig hypothala-mus
    • Laurence D, Daniele L, Maryvonne W: Differential effects of colchicine on the induction of nitric oxide synthase in neurons containing progesterone receptors of the guinea pig hypothala-mus. Brain Res Bull 2000;52:435-443.
    • (2000) Brain Res Bull , vol.52 , pp. 435-443
    • Laurence, D.1    Daniele, L.2    Maryvonne, W.3
  • 41
    • 0027732055 scopus 로고
    • Neuropro-tection against nitric oxide injury with inhibitors of ADP-ribosylation
    • Wallis RA, Panizzon KL, Henry D, Wasterlain CG: Neuropro-tection against nitric oxide injury with inhibitors of ADP-ribosylation. Neuroreport 1993;5:245-248.
    • (1993) Neuroreport , vol.5 , pp. 245-248
    • Wallis, R.A.1    Panizzon, K.L.2    Henry, D.3    Wasterlain, C.G.4
  • 42
    • 0037968844 scopus 로고    scopus 로고
    • Effects of naringin on hydrogen peroxide-induced cytotoxicity and apoptosis in p388 cells
    • Kanno S, Shouji A, Asou K, Ishikawa M: Effects of naringin on hydrogen peroxide-induced cytotoxicity and apoptosis in p388 cells. J Pharmacol Sci 2003;92:166-170.
    • (2003) J Pharmacol Sci , vol.92 , pp. 166-170
    • Kanno, S.1    Shouji, A.2    Asou, K.3    Ishikawa, M.4
  • 43
    • 0031418498 scopus 로고    scopus 로고
    • Neurodegenerative disorders in humans: The role of glutathione in oxidative stress-mediated neuronal death
    • Bains JS, Shaw CA: Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death. Brain Res Brain Res Rev 1997;25:335-358.
    • (1997) Brain Res Brain Res Rev , vol.25 , pp. 335-358
    • Bains, J.S.1    Shaw, C.A.2
  • 44
    • 0029125857 scopus 로고
    • Ageing, energy and oxidative stress in neurodegener-ative disease
    • Beal MF: Ageing, energy and oxidative stress in neurodegener-ative disease. Ann Neurol 1995;38:357-366.
    • (1995) Ann Neurol , vol.38 , pp. 357-366
    • Beal, M.F.1
  • 45
    • 0028969188 scopus 로고
    • The relation of oxidative stress and hyperexcitation to neurological disease
    • Bondy CS: The relation of oxidative stress and hyperexcitation to neurological disease. Proc Soc Exp Biol Med 1995;208:337-345.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 337-345
    • Bondy, C.S.1
  • 46
    • 0029147523 scopus 로고
    • Excitotoxins, aging and environmental neurotoxins: Implications for understanding human neurodegenerative diseases
    • Dawson R Jr, Beal MF, Bondy SC, Di Monte DA, Isom GE: Excitotoxins, aging and environmental neurotoxins: implications for understanding human neurodegenerative diseases. Toxicol Appl Pharmacol 1995;134:157-167.
    • (1995) Toxicol Appl Pharmacol , vol.134 , pp. 157-167
    • Dawson Jr., R.1    Beal, M.F.2    Bondy, S.C.3    Di Monte, D.A.4    Isom, G.E.5
  • 47
    • 0034615834 scopus 로고    scopus 로고
    • Differential vulnerability of primary cultured cholinergic neurons to nitric oxide excess
    • Fass U, Panickar K, Personett D, et al.: Differential vulnerability of primary cultured cholinergic neurons to nitric oxide excess. Neuroreport 2000;11:931-936.
    • (2000) Neuroreport , vol.11 , pp. 931-936
    • Fass, U.1    Panickar, K.2    Personett, D.3
  • 48
    • 13844271390 scopus 로고    scopus 로고
    • Dietary polyphe-nols protect dopamine neurons from oxidative insults and apoptosis: Investigations in primary mesencephalic cultures
    • Mercer LD, Kelly BL, Horne MK, Beart PM: Dietary polyphe-nols protect dopamine neurons from oxidative insults and apoptosis: investigations in primary mesencephalic cultures. Biochem Pharmacol 2005;69:339-345
    • (2005) Biochem Pharmacol , vol.69 , pp. 339-345
    • Mercer, L.D.1    Kelly, B.L.2    Horne, M.K.3    Beart, P.M.4
  • 49
    • 0030818058 scopus 로고    scopus 로고
    • Current concepts in the patho-genesis of Alzheimer's disease
    • Carr DB, Goate A, Morris JC: Current concepts in the patho-genesis of Alzheimer's disease. Am J Med 1997;103(3A):3S-10S.
    • (1997) Am J Med , vol.103 , Issue.3 A
    • Carr, D.B.1    Goate, A.2    Morris, J.C.3
  • 50
    • 0031985192 scopus 로고    scopus 로고
    • Peripheral markers in testing pathophysiological hypothesis and diagnosing Alzheimer's disease
    • Gasparini L, Rasshi M, Binetti G, et al.: Peripheral markers in testing pathophysiological hypothesis and diagnosing Alzheimer's disease. FASEB J 1998;12:17-34.
    • (1998) FASEB J , vol.12 , pp. 17-34
    • Gasparini, L.1    Rasshi, M.2    Binetti, G.3
  • 51
    • 0343394802 scopus 로고
    • Preferential neurotoxicity of col-chicine for granule cells of dentate gyrus of the adult rat
    • Goldschmidt RB, Steward O: Preferential neurotoxicity of col-chicine for granule cells of dentate gyrus of the adult rat. Proc Natl Acad Sci USA 1980;77:3047-3051.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 3047-3051
    • Goldschmidt, R.B.1    Steward, O.2
  • 52
    • 0024416282 scopus 로고
    • Colchicine induced alterations of reference memory in rats: Role of spatial versus non-spatial task components
    • Kevin PN, William RM, Hugh AT: Colchicine induced alterations of reference memory in rats: role of spatial versus non-spatial task components. Behav Brain Res 1989;35:45-53.
    • (1989) Behav Brain Res , vol.35 , pp. 45-53
    • Kevin, P.N.1    William, R.M.2    Hugh, A.T.3
  • 53
    • 0038022917 scopus 로고    scopus 로고
    • Restorative potential of cholinergic rich transplants in cholchicine induced lesioned rats: A comparative study of single and multiple micro-transplantation approach
    • Agrawal AK, Roy A, Seth K, Raghubir R, Seth PK: Restorative potential of cholinergic rich transplants in cholchicine induced lesioned rats: a comparative study of single and multiple micro-transplantation approach. Int J Dev Neurosci 2003;21:191-198.
    • (2003) Int J Dev Neurosci , vol.21 , pp. 191-198
    • Agrawal, A.K.1    Roy, A.2    Seth, K.3    Raghubir, R.4    Seth, P.K.5
  • 54
    • 0034003669 scopus 로고    scopus 로고
    • Protective effect of L-phenylalanine on rat brain acetylcholinesterase inhibition induced by free radicals
    • DOI 10.1016/S0009-9120(99)00090-9, PII S0009912099000909
    • Tsakiris S, Angelogianni P, Schulpis KH, Stavridis JC: Protective effect of l-phenylalanine on rat brain acetylcholinesterase inhibition induced by free radicals. Clin Biochem 2000;33:103-106. (Pubitemid 30212817)
    • (2000) Clinical Biochemistry , vol.33 , Issue.2 , pp. 103-106
    • Tsakiris, S.1    Angelogianni, P.2    Schulpis, K.H.3    Stavridis, J.C.4
  • 55
    • 67349249432 scopus 로고    scopus 로고
    • Acetylcholine inhibits nitric oxide (NO) synthesis in the gastropod nervous system
    • Roszer T, Józsa T, Szentmiklósi AJ, Bánfalvi G: Acetylcholine inhibits nitric oxide (NO) synthesis in the gastropod nervous system. Cell Tissue Res 2009;336:325-335.
    • (2009) Cell Tissue Res , vol.336 , pp. 325-335
    • Roszer, T.1    Józsa, T.2    Szentmiklósi, A.J.3    Bánfalvi, G.4
  • 56
    • 0020052709 scopus 로고
    • Neurotoxic effects of colchicine: Differential susceptibility of CNS neuronal populations
    • Goldschmidt RB, Steward O: Neurotoxic effects of colchicine: differential susceptibility of CNS neuronal populations. Neu-roscience 1982;7:695-714.
    • (1982) Neu-roscience , vol.7 , pp. 695-714
    • Goldschmidt, R.B.1    Steward, O.2
  • 57
    • 0029072217 scopus 로고
    • Colchicine induces apoptosis in cerebellar granule cells
    • Bonfoco E, Ceccatelli S, Manzo L, Nicotera P: Colchicine induces apoptosis in cerebellar granule cells. Exp Cell Res 1995; 218:189-200.
    • (1995) Exp Cell Res , vol.218 , pp. 189-200
    • Bonfoco, E.1    Ceccatelli, S.2    Manzo, L.3    Nicotera, P.4
  • 58
    • 0035802898 scopus 로고    scopus 로고
    • Estrogens modulate experimentally induced apoptosis of granule cells in the adult hippocampus
    • Liu Z, Gastard M, Verina T, Bora S, Mouton PR, Koliatsos VE: Estrogens modulate experimentally induced apoptosis of granule cells in the adult hippocampus. J Comp Neurol 2001;441:1-8.
    • (2001) J Comp Neurol , vol.441 , pp. 1-8
    • Liu, Z.1    Gastard, M.2    Verina, T.3    Bora, S.4    Mouton, P.R.5    Koliatsos, V.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.