A novel butyrolactone derivative inhibited smooth muscle cell migration and proliferation and maintained endothelial cell functions through selectively affecting Na, K-ATPase activity and mitochondria membrane potential during in vitro angiogenesis

Journal of Cellular Biochemistry

Volumn 104, Issue 6, 2008, Pages 2123-2130

  Meng, Ning ^a,b   Zhao, Jing ^a,b   Zhao, BaoXiang ^a   Cheng, Yizhe ^a,b   Wang, Weiwei ^a,b   Zhang, Yun ^b   Zhang, Shangli ^a,b   Miao, JunYing ^a,b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Angiogenesis; Mitochondrial membrane potential; Na, K ATPase; Vascular endothelial cell; Vascular smooth muscle cell

Indexed keywords

3 BENZYL 5 [(NITROPHENOXY)METHYL]DIHYDROFURAN 2(3H) ONE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); LACTONE DERIVATIVE; TETRAMETHYLRHODAMINE METHYL ESTER;

ANALYTIC METHOD; ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; SPECTROPHOTOMETRY; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL MOVEMENT; CELL PROLIFERATION; COLLAGEN; DRUG COMBINATIONS; ENDOTHELIAL CELLS; HUMANS; LACTONES; LAMININ; MEMBRANE POTENTIAL, MITOCHONDRIAL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEOGLYCANS; RATS; SODIUM-POTASSIUM-EXCHANGING ATPASE;

RATTUS;

EID: 49049088110     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21769     Document Type: Article

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