The effect of D-methionine on cochlear oxidative state with and without cisplatin administration: Mechanisms of otoprotection

Journal of the American Academy of Audiology

Volumn 14, Issue 3, 2003, Pages 144-156

  Campbell, Kathleen C M ^a   Meech, Robert P ^a   Rybak, Leonard P ^a   Hughes, Larry F ^a  

^a SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidants; Auditory brainstem response; Catalase; Cisplatin; Enzymes; Glutathione peroxidase; Glutathione reductase; Hearing; Malondiadehyde; Ototoxicity; Superoxide dismutase

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; CISPLATIN; METHIONINE; NEUROPROTECTIVE AGENT;

ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; COCHLEA; DRUG EFFECT; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING LOSS; INTRAMUSCULAR DRUG ADMINISTRATION; LIPID PEROXIDATION; METABOLISM; OXIDATION REDUCTION REACTION; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CISPLATIN; COCHLEA; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; HEARING LOSS; INJECTIONS, INTRAMUSCULAR; LIPID PEROXIDATION; METHIONINE; NEUROPROTECTIVE AGENTS; OXIDATION-REDUCTION; RATS;

EID: 0141575856     PISSN: 10500545     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Aebi H. (1984). Catalase in vitro. Meth. Enzymol. 105:121-126.
2. Benevenga NJ. (1974). Toxicities of methionine and other amino acids. J. Agr. Food Chem 22(1):2-9.
3. Berry JM, Jacobs C, Sikic B, Jalsey J, Borch RF. (1990). Modification of cisplatin toxicity with diethyldithiocarbamate. Journal of Clinical Oncology 8(9):1585-1590.
4. Blakley BW, Meyers SF (1993). Patterns of hearing loss resulting from cis-platinum chemotherapy. Otolaryngol Head Neck Surg 109(3 pt 1):385-91.
5. Blakley BW, Gupta AK, Myers SF, Schwan S. (1994). Risk factors for ototoxicity due to cisplatin. Arch Otolaryngol Head Neck Surg 120:541-546.
6. Blom HJ, Boers GHJ, Van Den Elzen JPAM, Gahl WA, Tangerman A. (1989). Transamination of methionine in humans. Clinical Science 76:43-49.
7. Campbell KCM, Rybak LP, Meech RP, Hughes LF. (1996). D-Methionine provides excellent protection from cisplatin ototoxicity in the rat. Hearing Research 102:90-98.
8. Campbell KCM, Meech RP, Rybak LP, Hughes LF. (1999). D-methionine protects against cisplatin damage to the stria vascularis. Hear. Res. 138:13-28.
9. Carlberg, I. and Mannervik, B. (1985). Glutathione reductase. Meth. Enzymol. 113:484-490.
10. Coleman KM, Liu J, Jackson R, Kopke RD. (2002). Post-noise administration of methionine attenuates noise-induced hearing loss in the chinchilla. Association for Research in Otolaryngology. Abs: 226.
11. Deegan P, Pratt I, Ryan M. (1994). The nephrotoxicity, cytotoxicity and renal handling of a cisplatin-methionine complex in male Wistar rats. Toxicology 89:1-14.
12. Ekborn A, Laurell G, Johnstrom P, Wallin I, Eksborg S, Ehrsson H. (2002). D-Methionine and cisplatin ototoxicity in the guinea pig: D-methionine influences cisplatin pharmacokinetics. Hearing Research 165: 53-61.
13. Fernandez-Checa JC, Kaplowitz N, Garcia-Ruiz C. Colell A. (1998). Mitochondrial Glutathione: Importance and Transport. Seminars in Liver Disease, 18 (4):389-401.
14. Flohe Land Gunzler W (1984). Assays of glutathione peroxidase. Meth. Enzymol. 105:114-121.
15. Friedman M (1999). Chemistry, nutrition, and microbiology of d-amino acids. J. Agric. Food Chem. 47:3457-3479.
16. Gabaizadeh R, Staeker H, Lui W, Kopke R, Malgrange B, Lebebre P, Van de Water T. (1997). Protection of both auditory hair cells and auditory neurons from cisplatin induced damage. Acta Otolaryngologica (Stockh) 117:232-238.
17. Ghibelli L, Fanelli C, Rotilio G, Lafavia E, Coppola S, Colussi C, Civitareale P, Ciriolo MR. (1998). Rescue of cells from apoptosis by inhibition of active GSH extrusion. FASEB Journal 12(6):479-86).
18. Gillette-Cloven N, Re A McHale M, Burger R, DiSaia P, Rose S, Campbell K, Fan H. (2000). Evaluation of D-methionine as a cytoprotectant in cisplatin treatment of an animal model for ovarian cancer. Anticancer Research 20:4205-4210.
19. Griffin JP. (1988). Drug-induced ototoxicity. British Journal of Audiology 22:195-210.
20. Hannemann J, Baumann K (1988). Cisplatin-induced lipid peroxidation and decrease of gluconeogenesis in rat kidney cortex: Different effects of antioxidants and radical scavengers. Toxicology 51:119-132.
21. Hoeve LJ, Mertens zur Borg IRAM, Rodenburg M, Brocaar MP Groen BGS. (1988). Correlations between cis-platinum dosage and toxicity in a guinea pig model. Archives of Otorhinolaryngology 245:98-102.
22. Ikeda K, Sunose H, Takasaka T. (1993). Effects of free radicals on the intracellular calcium concentration in the isolated outer hair cell of the guinea pig cochlea. Acta Otolaryngology (Stockh) 113:137-141.
23. Jones MM., Basinger MA. (1989). Thiol and thioester suppression of cis-platinum-induced nephrotoxicity in rats bearing the Walker 256 carcinosarcoma. Anticancer Res 9:1937-42.
24. Jones MM, Basinger MA, Holscher MA. (1991). Control of nephrotoxicity of cisplatin by clinically used sulfur-containing compounds. Fundam Appl Toxicol 18:181-188.
25. Kaji H, Niioka T, Kojima Y, Yoshida Y, Kawakami Y. (1987). Urinary 3-methylthiopropionate excretion and the effect of D- or L-methionine ingestion studied in healthy subjects. Res Commun Chem Pathol Pharmacol 56:101-109.
26. Kies C, Fox H, Aprahamian S. (1975). Comparative value of L-, DL-, and D-methionine supplementation of an oat-based diet for humans. Journal of Nutrition 105:809-814.
27. Koegel L. (1985). Ototoxicity: A contemporary review of aminoglycosides, loop diuretics, acetylsalicylic acid, quinine, erthromycin, and cisplatinum. The American Journal of Otology 6(2):190-199.
28. Kopke R, Liu W, Gabaizedeh R, Jacano A, Feghali J, Spray D, Garcia P, Steinman H, Malgrange B, Ruben R, Rybak L, Van de Water T. (1997). Use of organotypic cultures of corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells. The American Journal of Otology 18:559-571.
29. Kopke RD, Coleman JKM, Liu J, Campbell KCM, Riffenburgh RH. (2002). Enhancing intrinsic cochlear stress defenses to reduce noise-induced hearing loss. The Laryngoscope 112:1515-1532.
30. Korver KD, Rybak LP, Whitworth C A, Hughes LF, Campbell KCM. (1998). Round window application of D-methionine provides cisplatin otoprotection. Assoc Res Otolaryngol Abs:135.
31. Korver KD, Rybak LP, Whitworth C A, Campbell KCM. (2002). Round window application of D-methionine provides complete cisplatin otoprotection. Otolaryngol Head Neck Surg 126(6):683-689.
32. Kroger H, Dietrich A, Ohde M, Lange R, Ehrlich W Kurpisz M. (1997). Protection from acetaminophen-induced liver damage by the synergistic action of low doses of the poly (ADP-ribose) polymerase-inhibitor nicotinamide and the antioxidant N-Acetylcysteine or the amino acid L-methionine. Gen Pharmacol 28(2):257-263.
33. Lu S. (1998). Regulation of hepatic glutathione synthesis. Sem in Liver Dis 18:331-334.
34. McAlpine D, Johnstone BM. (1990).The ototoxic mechanism of cisplatin. Hearing Research 47:191-204.
35. Melvik J, Pettersen E. (1987). Reduction of cis-Dichloro diammine platinum-induced cell inactivation by methionine. Inorganica Chimica Acta. 137:115-118.
36. Meyer GJ, Schober O, Hundeshagen H. (1985). Uptake of C-L- and D-methionine in brain tumors. Eur J Nucl Med 10:373-376.
37. Miller SE, House DA. (1990). The hydrolysis products of cis-dichlorodiammineplatinum (II). 3. Hydrolysis kinetics at physiological pH. Inorgan Chem Acta 173:53-60.
38. Misra, H.P., and Fridovich, I. (1972). The role of superoxide anion in the autooxidation of epinephrine and a sample assay for superoxide dismutase. J Biol Chem 247:3170-3175.
39. Moroso MJ, Blair RL. (1983). A review of cis-platinum ototoxicity. The Journal of Otolaryngology 12(6):365-369.
40. National Research Council (1980). Recommended Dietary Allowances, 9th rev. ed. Washington, D.C.: National Academy of Sciences.
41. Oberley LW, Oberley TD. (1986). Free Radicals, Cancer, and Aging. Free Radicals, Aging and Degenerative Diseases: Alan R. Liss Inc., New York, NY, p. 325-371.
42. Ohkawa H, Ohishi N, Yagi K. (1979). Assay for lipid peroxides in animals and tissues by thiobarbituric acid reactions. Anal Biochem 95:351-358.
43. Ohlemiller KK, Dugan LL. (1998). In vivo measurement of cochlear reactive oxygen species (ROS) in mice: Effects of noise exposure and cochlear ischemia. Assoc Res Otolaryngol Abs: 518.
44. Pierson MG, Gray BH. (1982). Superoxide dismutase activity in the cochlea. Hearing Research 6:141-151.
45. Qazi R, Chang AYC, Borch RF, Montine T, Dedon P, Loughner J, Bennett JM (1988). Phase I clinical and pharmacokinetic study of diethyldithiocarbamate as a chemoprotector from toxic effects of cisplatin. Journal of the National Cancer Institute 80(18):1486-1492.
46. Ravi R, Rybak LP, Somani SM. (1991). Relationship of pharmacodynamic effects of cisplatin to the glutathione levels in cochlea, inferion colliculus and kidney. Pharmacologist 33(3):217.
47. Ravi R, Rybak LP, Hoffman D, Whitworth C, Scott V. (1992). Diethyldithiocarbamate protects against cisplatin ototoxicity and nephrotoxicity. Otolaryngology Head and Neck Surgery 107(2):232.
48. Ravi R, Somani S, Rybak L. (1995). Mechanism of cisplatin ototoxicity: Antioxidant system. Pharmacology and Toxicology 76: 386-394.
49. Read, S.M. and Northcole, D.H. (1981). Minimization of variation in the response to different proteins of coomassie blue G dye-binding assay for protein. Anal Biochem 116:52-64.
50. Reser D, Rho M, Dewan D, Herbst L, Li G, Stupa H, Zur, Romaine J, Frenz D, Goldblum L, Kopke R, Arezzo J, Van De Water T. (1999). L- and D-methionine provide equivalent long term protection against CDDP-induced ototoxicity in vivo, with partial in vitro and in vivo retention of antineoplastic activity. Neurotoxicology 20(5):731-748.
51. Ross D. (1988). Glutathione, free radicals and chemotherapeutic agents. Pharmacology Therapy 37:231-249.
52. Rothenberg ML, Ostchega Y, Steinberg SM, Young RC, Hummel S, Ozols RF. (1988). High-dose carboplatin with diethylthiocarbamate protection in treatment of women with relapsed ovarian cancer. J Natl Cancer Inst 80:1488-1492.
53. Rybak LP, Hoffman DW, Whitworth C, Scott V. (1992). Comparative ototoxicity of cisplatin in the rat. Assoc Res Otolaryngol Abs:110.
54. Saito T, Moataz R, Dulon D. (1991). Cisplatin blocks depolarizatrion-induced calcium entry in isolated cochlear outer hair cells. Hearing Research 56:143-147.
55. Schröder M, Laskawi R, Stennert E, Kühnle H, Thiele FW. (1986). Cis-platin ototoxizität - eine klinische studie. Laryngology, Rhinology, & Otology 65:86-89.
56. Sha S, Schacht J. (2000). Antioxidants attenuate gentamicin-induced free radical formation in vitro and ototoxicity in vivo: D-methionine is a potential protectant. Hear Res 142:34-40.
57. Stegink LD, Bell EF, Filer Jr. LJ, Ziegler EE, Andersen DW, Seligson FH. (1986). Effects of equimolar doses of l-methionine, d-methionine and l-methionine-dl-sulfoxide on plasma and urinary amino acid levels in normal adult humans. J Nutr 116:1185-1192.
58. Stekol JA, Szaran, J. (1962). Pathological effects of excessive methionine in the diet of growing rats. J Nutr 77:81-90.
59. Vermorken JB, Kapteijn TS, Hart AAM, Pinedo HM. (1983). Ototoxicity of cis-diamminedichloroplatinum(II): Influence of dose, schedule and mode of admnistration. European Journal of Cancer & Clinical Oncology 19(1):53-58.
60. Vogt W. (1995). Oxidation of methionyl residues in proteins: Tools, targets, and reversal. Free Radic Biol Med 18:93-105.
61. Walser M, Coulter AW, Dighe S, Crantz. FR. (1973). The effect of keto-analogues of essential amino acids in severe chronic uremia. J Clin Invest 52:678.
62. WHO Expert Committee (1998). The use of essential drugs. Who Technical Report Series 882: World Health Organization, Geneva, Switzerland.
63. Yamamoto T, Kakehata S, Saito T, Saito H., Akaike N. (1994). Cisplatin blocks voltage-dependent calcium current in dissociated outer hair cells of guinea-pig cochlea. Brain Research 648:296-298.
64. Yamane H, Yoshiaki N, Takayama M, Konishi K, Iguchi H, Nakagawa T, Shibata S, Kato A, Sunami K, Kawakatsu C. (1995). The emergence of free radicals after acoustic trauma and strial blood flow. Acta Otolaryngol (Stockh), Suppl 519:87-92.