메뉴 건너뛰기




Volumn 14, Issue 6, 2015, Pages 692-698

Targeting the toll of drug abuse: The translational potential of toll-like receptor 4

Author keywords

(+) naloxone; (+) naltrexone; Alcohol; Cocaine; Drug reinforcement; Drug reward; Morphine; Opioid; Psychostimulants; Reinstatement

Indexed keywords

4 AMINOBUTYRIC ACID; ALCOHOL; AMPA RECEPTOR; BIOLOGICAL FACTOR; CD11B ANTIGEN; COCAINE; DOPAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; METHAMPHETAMINE; MYELOID DIFFERENTIATION FACTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE; NALTREXONE; NITRIC OXIDE; OPIATE; PROTEIN MD 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; NARCOTIC ANTAGONIST;

EID: 84933071385     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527314666150529132503     Document Type: Article
Times cited : (76)

References (71)
  • 1
    • 67349182481 scopus 로고    scopus 로고
    • The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex
    • Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature 2009; 458: 1191-5.
    • (2009) Nature , vol.458 , pp. 1191-1195
    • Park, B.S.1    Song, D.H.2    Kim, H.M.3    Choi, B.S.4    Lee, H.5    Lee, J.O.6
  • 2
    • 84887121400 scopus 로고    scopus 로고
    • Why is neuroimmunopharmacology crucial for the future of addiction research?
    • Hutchinson MR, Watkins LR. Why is neuroimmunopharmacology crucial for the future of addiction research? Neuropharmacology 2014; 76 Pt B: 218-27.
    • (2014) Neuropharmacology , vol.76 , pp. 218-227
    • Hutchinson, M.R.1    Watkins, L.R.2
  • 4
    • 0033529232 scopus 로고    scopus 로고
    • Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions
    • Mayer DJ, Mao J, Holt J, Price DD. Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions. Proc Natl Acad Sci USA 1999; 96: 7731-6.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7731-7736
    • Mayer, D.J.1    Mao, J.2    Holt, J.3    Price, D.D.4
  • 5
    • 0035111016 scopus 로고    scopus 로고
    • The involvement of glial cells in the development of morphine tolerance
    • Song P, Zhao ZQ. The involvement of glial cells in the development of morphine tolerance. Neurosci Res 2001; 39: 281-6.
    • (2001) Neurosci Res , vol.39 , pp. 281-286
    • Song, P.1    Zhao, Z.Q.2
  • 6
    • 0034026327 scopus 로고    scopus 로고
    • Spinal plasticity of acute opioid tolerance
    • Fairbanks CA, Wilcox GL. Spinal plasticity of acute opioid tolerance. J Biomed Sci 2000; 7: 200-12.
    • (2000) J Biomed Sci , vol.7 , pp. 200-212
    • Fairbanks, C.A.1    Wilcox, G.L.2
  • 7
    • 79960687433 scopus 로고    scopus 로고
    • Exploring the neuroimmunopharmacology of opioids: An integrative review of mechanisms of central immune signaling and their implications for opioid analgesia
    • Hutchinson MR, Shavit Y, Grace PM, Rice KC, Maier SF, Watkins LR. Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacol Rev 2011; 63: 772-810.
    • (2011) Pharmacol Rev , vol.63 , pp. 772-810
    • Hutchinson, M.R.1    Shavit, Y.2    Grace, P.M.3    Rice, K.C.4    Maier, S.F.5    Watkins, L.R.6
  • 8
    • 33845945382 scopus 로고    scopus 로고
    • Norman Cousins Lecture. Glia as the "bad guys": Implications for improving clinical pain control and the clinical utility of opioids
    • Watkins LR, Hutchinson MR, Ledeboer A, Wieseler-Frank J, Milligan ED, Maier SF. Norman Cousins Lecture. Glia as the "bad guys": implications for improving clinical pain control and the clinical utility of opioids. Brain Behav Immun 2007; 21: 131-46.
    • (2007) Brain Behav Immun , vol.21 , pp. 131-146
    • Watkins, L.R.1    Hutchinson, M.R.2    Ledeboer, A.3    Wieseler-Frank, J.4    Milligan, E.D.5    Maier, S.F.6
  • 9
    • 0027381134 scopus 로고
    • Glial fibrillary acidic protein and the mesolimbic dopamine system: Regulation by chronic morphine and Lewis-Fischer strain differences in the rat ventral tegmental area
    • Beitner-Johnson D, Guitart X, Nestler EJ. Glial fibrillary acidic protein and the mesolimbic dopamine system: regulation by chronic morphine and Lewis-Fischer strain differences in the rat ventral tegmental area. J Neurochem 1993; 61: 1766-73.
    • (1993) J Neurochem , vol.61 , pp. 1766-1773
    • Beitner-Johnson, D.1    Guitart, X.2    Nestler, E.J.3
  • 10
    • 71749111875 scopus 로고    scopus 로고
    • Evidence that opioids may have toll-like receptor 4 and MD-2 effects
    • Hutchinson MR, Zhang Y, Shridhar M, et al. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun 2010; 24: 83-95.
    • (2010) Brain Behav Immun , vol.24 , pp. 83-95
    • Hutchinson, M.R.1    Zhang, Y.2    Shridhar, M.3
  • 11
    • 77951299280 scopus 로고    scopus 로고
    • Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences
    • Hutchinson MR, Lewis SS, Coats BD, et al. Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience 2010; 167: 880-93.
    • (2010) Neuroscience , vol.167 , pp. 880-893
    • Hutchinson, M.R.1    Lewis, S.S.2    Coats, B.D.3
  • 12
    • 54049124717 scopus 로고    scopus 로고
    • Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: Involvement of toll-like receptor 4 (TLR4)
    • Hutchinson MR, Zhang Y, Brown K, et al. Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). Eur J Neurosci 2008; 28: 20-9.
    • (2008) Eur J Neurosci , vol.28 , pp. 20-29
    • Hutchinson, M.R.1    Zhang, Y.2    Brown, K.3
  • 13
    • 84860012585 scopus 로고    scopus 로고
    • Morphine activates neuroinflammation in a manner parallel to endotoxin
    • Wang X, Loram LC, Ramos K, et al. Morphine activates neuroinflammation in a manner parallel to endotoxin. Proc Natl Acad Sci USA 2012; 109: 6325-30.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 6325-6330
    • Wang, X.1    Loram, L.C.2    Ramos, K.3
  • 14
    • 84934766319 scopus 로고    scopus 로고
    • DAT isn't all that: Cocaine reward and reinforcement requires Toll Like Receptor 4 signaling
    • Epub ahead of print
    • Northcutt A, Hutchinson M, Wang X, et al. DAT isn't all that: cocaine reward and reinforcement requires Toll Like Receptor 4 signaling. Mol Psychiatry 2014; Epub ahead of print.
    • (2014) Mol Psychiatry
    • Northcutt, A.1    Hutchinson, M.2    Wang, X.3
  • 15
    • 27744562724 scopus 로고    scopus 로고
    • Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes
    • Blanco AM, Valles SL, Pascual M, Guerri C. Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. J Immunol 2005; 175: 6893-9.
    • (2005) J Immunol , vol.175 , pp. 6893-6899
    • Blanco, A.M.1    Valles, S.L.2    Pascual, M.3    Guerri, C.4
  • 17
    • 80053487700 scopus 로고    scopus 로고
    • Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions
    • Meng J, Gong M, Bjorkbacka H, Golenbock DT. Genome-wide expression profiling and mutagenesis studies reveal that lipopolysaccharide responsiveness appears to be absolutely dependent on TLR4 and MD-2 expression and is dependent upon intermolecular ionic interactions. J Immunol 2011; 187: 3683-93.
    • (2011) J Immunol , vol.187 , pp. 3683-3693
    • Meng, J.1    Gong, M.2    Bjorkbacka, H.3    Golenbock, D.T.4
  • 18
    • 0020806965 scopus 로고
    • Action of an opiate receptor blocker on ovine cardiopulmonary responses to endotoxin
    • Traber DL, Thomson PD, Blalock JE, et al. Action of an opiate receptor blocker on ovine cardiopulmonary responses to endotoxin. Am J Physiol 1983; 245: H189-93.
    • (1983) Am J Physiol , vol.245 , pp. 189-193
    • Traber, D.L.1    Thomson, P.D.2    Blalock, J.E.3
  • 19
    • 0020675219 scopus 로고
    • Effect of naloxone treatment on the cardiopulmonary response to endotoxin in sheep
    • Sziebert L, Thomson PD, Jinkins J, et al. Effect of naloxone treatment on the cardiopulmonary response to endotoxin in sheep. Adv Shock Res 1983; 10: 121-8.
    • (1983) Adv Shock Res , vol.10 , pp. 121-128
    • Sziebert, L.1    Thomson, P.D.2    Jinkins, J.3
  • 21
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-8.
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1    He, X.2    Smirnova, I.3
  • 22
    • 84904128683 scopus 로고    scopus 로고
    • Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala
    • Bajo M, Madamba SG, Roberto M, et al. Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala. Brain Behav Immun 2014; 40: 191-202.
    • (2014) Brain Behav Immun , vol.40 , pp. 191-202
    • Bajo, M.1    Madamba, S.G.2    Roberto, M.3
  • 23
    • 84875410768 scopus 로고    scopus 로고
    • Intrahippocampal injection of lipopolysaccharide inhibits kindled seizures and retards kindling rate in adult rats
    • Ahmadi A, Sayyah M, Khoshkholgh-Sima B, et al. Intrahippocampal injection of lipopolysaccharide inhibits kindled seizures and retards kindling rate in adult rats. Exp Brain Res 2013; 226: 107-20.
    • (2013) Exp Brain Res , vol.226 , pp. 107-120
    • Ahmadi, A.1    Sayyah, M.2    Khoshkholgh-Sima, B.3
  • 24
    • 0345304249 scopus 로고    scopus 로고
    • The bacterial endotoxin lipopolysaccharide enhances seizure susceptibility in mice: Involvement of proinflammatory factors: Nitric oxide and prostaglandins
    • Sayyah M, Javad-Pour M, Ghazi-Khansari M. The bacterial endotoxin lipopolysaccharide enhances seizure susceptibility in mice: involvement of proinflammatory factors: nitric oxide and prostaglandins. Neuroscience 2003; 122: 1073-80.
    • (2003) Neuroscience , vol.122 , pp. 1073-1080
    • Sayyah, M.1    Javad-Pour, M.2    Ghazi-Khansari, M.3
  • 25
    • 84867569777 scopus 로고    scopus 로고
    • Naloxone inhibition of lipopolysaccharide-induced activation of retinal microglia is partly mediated via the p38 mitogen activated protein kinase signalling pathway
    • Xu YF, Fu LL, Jiang CH, Qin YW, Ni YQ, Fan JW. Naloxone inhibition of lipopolysaccharide-induced activation of retinal microglia is partly mediated via the p38 mitogen activated protein kinase signalling pathway. J Int Med Res 2012; 40: 1438-48.
    • (2012) J Int Med Res , vol.40 , pp. 1438-1448
    • Xu, Y.F.1    Fu, L.L.2    Jiang, C.H.3    Qin, Y.W.4    Ni, Y.Q.5    Fan, J.W.6
  • 26
    • 84872971637 scopus 로고    scopus 로고
    • Inhibition of LPSinduced retinal microglia activation by naloxone does not prevent photoreceptor death
    • Jiang X, Ni Y, Liu T, Zhang M, Ren H, Xu G. Inhibition of LPSinduced retinal microglia activation by naloxone does not prevent photoreceptor death. Inflammation 2013; 36: 42-52.
    • (2013) Inflammation , vol.36 , pp. 42-52
    • Jiang, X.1    Ni, Y.2    Liu, T.3    Zhang, M.4    Ren, H.5    Xu, G.6
  • 27
    • 84858007763 scopus 로고    scopus 로고
    • Naloxone in ultralow concentration restores endomorphin-1-evoked Ca(2)(+) signaling in lipopolysaccharide pretreated astrocytes
    • Block L, Forshammar J, Westerlund A, et al. Naloxone in ultralow concentration restores endomorphin-1-evoked Ca(2)(+) signaling in lipopolysaccharide pretreated astrocytes. Neuroscience 2012; 205: 1-9.
    • (2012) Neuroscience , vol.205 , pp. 1-9
    • Block, L.1    Forshammar, J.2    Westerlund, A.3
  • 28
    • 84912125708 scopus 로고    scopus 로고
    • Anti-inflammation effects of naloxone involve phosphoinositide 3-kinase delta and gamma
    • Wang TY, Su NY, Shih PC, Tsai PS, Huang CJ. Anti-inflammation effects of naloxone involve phosphoinositide 3-kinase delta and gamma. J Surg Res 2014; 192(2): 599-606.
    • (2014) J Surg Res , vol.192 , Issue.2 , pp. 599-606
    • Wang, T.Y.1    Su, N.Y.2    Shih, P.C.3    Tsai, P.S.4    Huang, C.J.5
  • 29
    • 84858159054 scopus 로고    scopus 로고
    • Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase
    • Wang Q, Zhou H, Gao H, et al. Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase. J Neuroinflammation 2012; 9: 32.
    • (2012) J Neuroinflammation , vol.9
    • Wang, Q.1    Zhou, H.2    Gao, H.3
  • 30
    • 33750487477 scopus 로고    scopus 로고
    • A novel inhibitory effect of naloxone on macrophage activation and atherosclerosis formation in mice
    • Liu SL, Li YH, Shi GY, et al. A novel inhibitory effect of naloxone on macrophage activation and atherosclerosis formation in mice. J Am Coll Cardiol 2006; 48: 1871-9.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1871-1879
    • Liu, S.L.1    Li, Y.H.2    Shi, G.Y.3
  • 31
    • 79955971116 scopus 로고    scopus 로고
    • Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia
    • Shen D, Cao X, Zhao L, Tuo J, Wong WT, Chan CC. Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia. Invest Ophthalmol Vis Sci 2011; 52: 2897-904.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 2897-2904
    • Shen, D.1    Cao, X.2    Zhao, L.3    Tuo, J.4    Wong, W.T.5    Chan, C.C.6
  • 32
    • 72849138642 scopus 로고    scopus 로고
    • Synergistic dopaminergic neurotoxicity of manganese and lipopolysaccharide: Differential involvement of microglia and astroglia
    • Zhang P, Lokuta KM, Turner DE, Liu B. Synergistic dopaminergic neurotoxicity of manganese and lipopolysaccharide: differential involvement of microglia and astroglia. J Neurochem 2010; 112: 434-43.
    • (2010) J Neurochem , vol.112 , pp. 434-443
    • Zhang, P.1    Lokuta, K.M.2    Turner, D.E.3    Liu, B.4
  • 33
    • 0033810830 scopus 로고    scopus 로고
    • Systemic infusion of naloxone reduces degeneration of rat substantia nigral dopaminergic neurons induced by intranigral injection of lipopolysaccharide
    • Liu B, Jiang JW, Wilson BC, et al. Systemic infusion of naloxone reduces degeneration of rat substantia nigral dopaminergic neurons induced by intranigral injection of lipopolysaccharide. J Pharmacol Exp Ther 2000; 295: 125-32.
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 125-132
    • Liu, B.1    Jiang, J.W.2    Wilson, B.C.3
  • 34
    • 0034072541 scopus 로고    scopus 로고
    • Reduction by naloxone of lipopolysaccharide-induced neurotoxicity in mouse cortical neuronglia co-cultures
    • Liu B, Du L, Kong LY, et al. Reduction by naloxone of lipopolysaccharide-induced neurotoxicity in mouse cortical neuronglia co-cultures. Neuroscience 2000; 97: 749-56.
    • (2000) Neuroscience , vol.97 , pp. 749-756
    • Liu, B.1    Du, L.2    Kong, L.Y.3
  • 35
    • 56649109909 scopus 로고    scopus 로고
    • Naltrexone protects against lipopolysaccharide/D-galactosamineinduced hepatitis in mice
    • Wang CC, Cheng PY, Peng YJ, Wu ES, Wei HP, Yen MH. Naltrexone protects against lipopolysaccharide/D-galactosamineinduced hepatitis in mice. J Pharmacol Sci 2008; 108: 239-47.
    • (2008) J Pharmacol Sci , vol.108 , pp. 239-247
    • Wang, C.C.1    Cheng, P.Y.2    Peng, Y.J.3    Wu, E.S.4    Wei, H.P.5    Yen, M.H.6
  • 36
    • 21244506076 scopus 로고    scopus 로고
    • Effects of naltrexone on lipopolysaccharide-induced sepsis in rats
    • Lin SL, Lee YM, Chang HY, Cheng YW, Yen MH. Effects of naltrexone on lipopolysaccharide-induced sepsis in rats. J Biomed Sci 2005; 12: 431-40.
    • (2005) J Biomed Sci , vol.12 , pp. 431-440
    • Lin, S.L.1    Lee, Y.M.2    Chang, H.Y.3    Cheng, Y.W.4    Yen, M.H.5
  • 37
    • 3242717651 scopus 로고    scopus 로고
    • The opioid antagonist naltrexone blocks acute endotoxic shock by inhibiting tumor necrosis factor-alpha production
    • Greeneltch KM, Haudenschild CC, Keegan AD, Shi Y. The opioid antagonist naltrexone blocks acute endotoxic shock by inhibiting tumor necrosis factor-alpha production. Brain Behav Immun 2004; 18: 476-84.
    • (2004) Brain Behav Immun , vol.18 , pp. 476-484
    • Greeneltch, K.M.1    Haudenschild, C.C.2    Keegan, A.D.3    Shi, Y.4
  • 38
    • 1642588146 scopus 로고    scopus 로고
    • Inhibitory effects of endotoxin on LH secretion in the ovariectomized monkey are prevented by naloxone but not by an interleukin-1 receptor antagonist
    • Xiao E, Xia-Zhang L, Ferin M. Inhibitory effects of endotoxin on LH secretion in the ovariectomized monkey are prevented by naloxone but not by an interleukin-1 receptor antagonist. Neuroimmunomodulation 2000; 7: 6-15.
    • (2000) Neuroimmunomodulation , vol.7 , pp. 6-15
    • Xiao, E.1    Xia-Zhang, L.2    Ferin, M.3
  • 39
    • 0027995710 scopus 로고
    • Peripheral naloxone attenuates lipopolysaccharide fever in guinea pigs by an action outside the blood-brain barrier
    • Romanovsky AA, Shido O, Ungar AL, Blatteis CM. Peripheral naloxone attenuates lipopolysaccharide fever in guinea pigs by an action outside the blood-brain barrier. Am J Physiol 1994; 266: R1824-31.
    • (1994) Am J Physiol , vol.266 , pp. 1824-1831
    • Romanovsky, A.A.1    Shido, O.2    Ungar, A.L.3    Blatteis, C.M.4
  • 40
    • 70449526311 scopus 로고    scopus 로고
    • Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats
    • Hutchinson MR, Ramos KM, Loram LC, et al. Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience 2009; 164: 1821-32.
    • (2009) Neuroscience , vol.164 , pp. 1821-1832
    • Hutchinson, M.R.1    Ramos, K.M.2    Loram, L.C.3
  • 41
    • 33750930263 scopus 로고    scopus 로고
    • Dextro-Naloxone or levo-naloxone reverses the attenuation of morphine antinociception induced by lipopolysaccharide in the mouse spinal cord via a non-opioid mechanism
    • Wu HE, Sun HS, Cheng CW, Terashvili M, Tseng LF. dextro-Naloxone or levo-naloxone reverses the attenuation of morphine antinociception induced by lipopolysaccharide in the mouse spinal cord via a non-opioid mechanism. Eur J Neurosci 2006; 24: 2575-80.
    • (2006) Eur J Neurosci , vol.24 , pp. 2575-2580
    • Wu, H.E.1    Sun, H.S.2    Cheng, C.W.3    Terashvili, M.4    Tseng, L.F.5
  • 42
    • 4944220173 scopus 로고    scopus 로고
    • Inhibition of morphine analgesia by LPS: Role of opioid and NMDA receptors and spinal glia
    • Johnston IN, Westbrook RF. Inhibition of morphine analgesia by LPS: role of opioid and NMDA receptors and spinal glia. Behav Brain Res 2005; 156: 75-83.
    • (2005) Behav Brain Res , vol.156 , pp. 75-83
    • Johnston, I.N.1    Westbrook, R.F.2
  • 43
    • 0034015558 scopus 로고    scopus 로고
    • Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation
    • Liu B, Du L, Hong JS. Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation. J Pharmacol Exp Ther 2000; 293: 607-17.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 607-617
    • Liu, B.1    Du, L.2    Hong, J.S.3
  • 44
    • 84860672423 scopus 로고    scopus 로고
    • (+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats
    • Lewis SS, Loram LC, Hutchinson MR, et al. (+)-naloxone, an opioid-inactive toll-like receptor 4 signaling inhibitor, reverses multiple models of chronic neuropathic pain in rats. J Pain 2012; 13: 498-506.
    • (2012) J Pain , vol.13 , pp. 498-506
    • Lewis, S.S.1    Loram, L.C.2    Hutchinson, M.R.3
  • 45
    • 84864995393 scopus 로고    scopus 로고
    • Opioid activation of toll-like receptor 4 contributes to drug reinforcement
    • Hutchinson MR, Northcutt AL, Hiranita T, et al. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. J Neurosci 2012; 32: 11187-200.
    • (2012) J Neurosci , vol.32 , pp. 11187-11200
    • Hutchinson, M.R.1    Northcutt, A.L.2    Hiranita, T.3
  • 47
    • 43449123329 scopus 로고    scopus 로고
    • Neuroplasticity in the mesolimbic dopamine system and cocaine addiction
    • Thomas MJ, Kalivas PW, Shaham Y. Neuroplasticity in the mesolimbic dopamine system and cocaine addiction. Br J Pharmacol 2008; 154: 327-42.
    • (2008) Br J Pharmacol , vol.154 , pp. 327-342
    • Thomas, M.J.1    Kalivas, P.W.2    Shaham, Y.3
  • 48
    • 33750320047 scopus 로고    scopus 로고
    • BHT blocks NF-kappaB activation and ethanol-induced brain damage
    • Crews F, Nixon K, Kim D, et al. BHT blocks NF-kappaB activation and ethanol-induced brain damage. Alcohol Clin Exp Res 2006; 30: 1938-49.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1938-1949
    • Crews, F.1    Nixon, K.2    Kim, D.3
  • 49
    • 77951535281 scopus 로고    scopus 로고
    • Induction of innate immune gene expression cascades in brain slice cultures by ethanol: Key role of NF-kappaB and proinflammatory cytokines
    • Zou J, Crews F. Induction of innate immune gene expression cascades in brain slice cultures by ethanol: key role of NF-kappaB and proinflammatory cytokines. Alcohol Clin Exp Res 2010; 34: 777-89.
    • (2010) Alcohol Clin Exp Res , vol.34 , pp. 777-789
    • Zou, J.1    Crews, F.2
  • 51
    • 84919845873 scopus 로고    scopus 로고
    • Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence
    • Bell RL, Lopez MF, Cui C, et al. Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence. Addict Biol 2013; 20(1): 38-42.
    • (2013) Addict Biol , vol.20 , Issue.1 , pp. 38-42
    • Bell, R.L.1    Lopez, M.F.2    Cui, C.3
  • 52
    • 11144275911 scopus 로고    scopus 로고
    • Genetic correlation between the free-choice oral consumption of nicotine and alcohol in C57BL/6JxC3H/HeJ F2 intercross mice
    • Li XC, Karadsheh MS, Jenkins PM, Stitzel JA. Genetic correlation between the free-choice oral consumption of nicotine and alcohol in C57BL/6JxC3H/HeJ F2 intercross mice. Behav Brain Res 2005; 157: 79-90.
    • (2005) Behav Brain Res , vol.157 , pp. 79-90
    • Li, X.C.1    Karadsheh, M.S.2    Jenkins, P.M.3    Stitzel, J.A.4
  • 53
    • 84863115604 scopus 로고    scopus 로고
    • Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice
    • Wu Y, Lousberg EL, Moldenhauer LM, et al. Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. Br J Pharmacol 2012; 165: 1319-29.
    • (2012) Br J Pharmacol , vol.165 , pp. 1319-1329
    • Wu, Y.1    Lousberg, E.L.2    Moldenhauer, L.M.3
  • 54
    • 77955403878 scopus 로고    scopus 로고
    • A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
    • Yang H, Hreggvidsdottir HS, Palmblad K, et al. A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proc Natl Acad Sci USA 2010; 107: 11942-7.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11942-11947
    • Yang, H.1    Hreggvidsdottir, H.S.2    Palmblad, K.3
  • 55
    • 84906732261 scopus 로고    scopus 로고
    • Discovery of a Novel Site of Opioid Action at the Innate Immune Pattern-Recognition Receptor TLR4 and its Role in Addiction
    • Jacobsen JH, Watkins LR, Hutchinson MR. Discovery of a Novel Site of Opioid Action at the Innate Immune Pattern-Recognition Receptor TLR4 and its Role in Addiction. Int Rev Neurobiol 2014; 118: 129-63.
    • (2014) Int Rev Neurobiol , vol.118 , pp. 129-163
    • Jacobsen, J.H.1    Watkins, L.R.2    Hutchinson, M.R.3
  • 56
    • 33750210542 scopus 로고    scopus 로고
    • Direct evidence of astrocytic modulation in the development of rewarding effects induced by drugs of abuse
    • Narita M, Miyatake M, Narita M, et al. Direct evidence of astrocytic modulation in the development of rewarding effects induced by drugs of abuse. Neuropsychopharmacology 2006; 31: 2476-88.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2476-2488
    • Narita, M.1    Miyatake, M.2    Narita, M.3
  • 57
    • 84889258933 scopus 로고    scopus 로고
    • Orally administered nanocurcumin to attenuate morphine tolerance: Comparison between negatively charged PLGA and partially and fully PEGylated nanoparticles
    • Shen H, Hu X, Szymusiak M, Wang ZJ, Liu Y. Orally administered nanocurcumin to attenuate morphine tolerance: comparison between negatively charged PLGA and partially and fully PEGylated nanoparticles. Mol Pharm 2013; 10: 4546-51.
    • (2013) Mol Pharm , vol.10 , pp. 4546-4551
    • Shen, H.1    Hu, X.2    Szymusiak, M.3    Wang, Z.J.4    Liu, Y.5
  • 58
    • 58849159101 scopus 로고    scopus 로고
    • Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast)
    • Hutchinson MR, Lewis SS, Coats BD, et al. Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain Behav Immun 2009; 23: 240-50.
    • (2009) Brain Behav Immun , vol.23 , pp. 240-250
    • Hutchinson, M.R.1    Lewis, S.S.2    Coats, B.D.3
  • 59
    • 84875696683 scopus 로고    scopus 로고
    • Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving
    • Theberge FR, Li X, Kambhampati S, et al. Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving. Biol Psychiatry 2013; 73: 729-37.
    • (2013) Biol Psychiatry , vol.73 , pp. 729-737
    • Theberge, F.R.1    Li, X.2    Kambhampati, S.3
  • 60
    • 77952422709 scopus 로고    scopus 로고
    • Opiates and the development of post-injury complications: A review
    • Schwacha MG. Opiates and the development of post-injury complications: a review. Int J Clin Exp Med 2008; 1: 42-9.
    • (2008) Int J Clin Exp Med , vol.1 , pp. 42-49
    • Schwacha, M.G.1
  • 62
    • 0032189943 scopus 로고    scopus 로고
    • Methamphetamine-induced increase in striatal NF-kappaB DNA-binding activity is attenuated in superoxide dismutase transgenic mice
    • Asanuma M, Cadet JL. Methamphetamine-induced increase in striatal NF-kappaB DNA-binding activity is attenuated in superoxide dismutase transgenic mice. Brain Res Mol Brain Res 1998; 60: 305-9.
    • (1998) Brain Res Mol Brain Res , vol.60 , pp. 305-309
    • Asanuma, M.1    Cadet, J.L.2
  • 63
    • 10444220272 scopus 로고    scopus 로고
    • Specific gene expression and possible involvement of inflammation in methamphetamine-induced neurotoxicity
    • Asanuma M, Miyazaki I, Higashi Y, Tsuji T, Ogawa N. Specific gene expression and possible involvement of inflammation in methamphetamine-induced neurotoxicity. Ann NY Acad Sci 2004; 1025: 69-75.
    • (2004) Ann NY Acad Sci , vol.1025 , pp. 69-75
    • Asanuma, M.1    Miyazaki, I.2    Higashi, Y.3    Tsuji, T.4    Ogawa, N.5
  • 64
    • 84874673840 scopus 로고    scopus 로고
    • Psychostimulant abuse and neuroinflammation: Emerging evidence of their interconnection
    • Clark KH, Wiley CA, Bradberry CW. Psychostimulant abuse and neuroinflammation: emerging evidence of their interconnection. Neurotox Res 2013; 23: 174-88.
    • (2013) Neurotox Res , vol.23 , pp. 174-188
    • Clark, K.H.1    Wiley, C.A.2    Bradberry, C.W.3
  • 65
    • 84873743669 scopus 로고    scopus 로고
    • Glial cell modulators attenuate methamphetamine self-administration in the rat
    • Snider SE, Hendrick ES, Beardsley PM. Glial cell modulators attenuate methamphetamine self-administration in the rat. Eur J Pharmacol 2013; 701: 124-30.
    • (2013) Eur J Pharmacol , vol.701 , pp. 124-130
    • Snider, S.E.1    Hendrick, E.S.2    Beardsley, P.M.3
  • 66
    • 84857785244 scopus 로고    scopus 로고
    • The glial cell modulators, ibudilast and its amino analog, AV1013, attenuate methamphetamine locomotor activity and its sensitization in mice
    • Snider SE, Vunck SA, van den Oord EJ, Adkins DE, McClay JL, Beardsley PM. The glial cell modulators, ibudilast and its amino analog, AV1013, attenuate methamphetamine locomotor activity and its sensitization in mice. Eur J Pharmacol 2012; 679: 75-80.
    • (2012) Eur J Pharmacol , vol.679 , pp. 75-80
    • Snider, S.E.1    Vunck, S.A.2    van den Oord, E.J.3    Adkins, D.E.4    McClay, J.L.5    Beardsley, P.M.6
  • 67
    • 84859996055 scopus 로고    scopus 로고
    • Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine
    • Chen H, Wu J, Zhang J, et al. Protective effects of the antioxidant sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine. Psychopharmacology 2012; 222: 37-45.
    • (2012) Psychopharmacology , vol.222 , pp. 37-45
    • Chen, H.1    Wu, J.2    Zhang, J.3
  • 68
    • 84893165924 scopus 로고    scopus 로고
    • Glial modulators as potential treatments of psychostimulant abuse
    • Beardsley PM, Hauser KF. Glial modulators as potential treatments of psychostimulant abuse. Adv Pharmacol 2014; 69: 1-69.
    • (2014) Adv Pharmacol , vol.69 , pp. 1-69
    • Beardsley, P.M.1    Hauser, K.F.2
  • 69
    • 84867293233 scopus 로고    scopus 로고
    • Methamphetamine activates nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) and induces human immunodeficiency virus (HIV) transcription in human microglial cells
    • Wires ES, Alvarez D, Dobrowolski C, et al. Methamphetamine activates nuclear factor kappa-light-chain-enhancer of activated B cells (NF-kappaB) and induces human immunodeficiency virus (HIV) transcription in human microglial cells. J Neurovirol 2012; 18: 400-10.
    • (2012) J Neurovirol , vol.18 , pp. 400-410
    • Wires, E.S.1    Alvarez, D.2    Dobrowolski, C.3
  • 70
    • 80054123331 scopus 로고    scopus 로고
    • Psychomotor stimulant effects of cocaine in rats and 15 mouse strains
    • Thomsen M, Caine SB. Psychomotor stimulant effects of cocaine in rats and 15 mouse strains. Exp Clin Psychopharmacol 2011; 19: 321-41.
    • (2011) Exp Clin Psychopharmacol , vol.19 , pp. 321-341
    • Thomsen, M.1    Caine, S.B.2
  • 71
    • 59349092024 scopus 로고    scopus 로고
    • Naloxone's pentapeptide binding site on filamin A blocks Mu opioid receptor-Gs coupling and CREB activation of acute morphine
    • Wang HY, Burns LH. Naloxone's pentapeptide binding site on filamin A blocks Mu opioid receptor-Gs coupling and CREB activation of acute morphine. PLoS One 2009; 4: e4282.
    • (2009) PLoS One , vol.4
    • Wang, H.Y.1    Burns, L.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.