Neuroplasticity in the mesolimbic dopamine system and cocaine addiction

British Journal of Pharmacology

Volumn 154, Issue 2, 2008, Pages 327-342

  Thomas, M J ^a   Kalivas, P W ^b   Shaham, Y ^c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

Actin cycling; Dopamine; Extracellular signal regulated kinase; Glutamate; Long term depression; Long term potentiation; Psychomotor sensitization; Reinstatement; Relapse; Synaptic plasticity

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; COCAINE; GLUTAMIC ACID; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE;

COCAINE DEPENDENCE; DISEASE MODEL; HUMAN; LEARNING; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MEMORY; MESOLIMBIC DOPAMINERGIC SYSTEM; NERVE CELL PLASTICITY; NEUROPHYSIOLOGY; NEUROTRANSMISSION; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PSYCHOMOTOR ACTIVITY; REVIEW; SENSITIZATION; SIGNAL TRANSDUCTION; VENTRAL TEGMENTUM;

ANIMALS; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; COCAINE-RELATED DISORDERS; DOPAMINE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GLUTAMIC ACID; HUMANS; LIMBIC SYSTEM; MODELS, ANIMAL; NEURAL PATHWAYS; NEURONAL PLASTICITY; PSYCHOMOTOR PERFORMANCE; RECURRENCE; SYNAPTIC TRANSMISSION;

EID: 43449123329     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.77     Document Type: Review

References (171)