The bacterial endotoxin lipopolysaccharide enhances seizure susceptibility in mice: Involvement of proinflammatory factors: Nitric oxide and prostaglandins

Neuroscience

Volumn 122, Issue 4, 2003, Pages 1073-1080

  Sayyah, M ^a   Javad Pour, M ^a,b   Ghazi Khansari, M ^b  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Epilepsy; Microglia; Naloxone; Neuroinflammation; Pentylenetetrazole

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; ESCHERICHIA COLI ENDOTOXIN; N(G) NITROARGININE METHYL ESTER; NALOXONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OPIATE ANTAGONIST; PENTETRAZOLE; PIROXICAM; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; DRUG EFFECT; INFUSION; MALE; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SEIZURE SUSCEPTIBILITY; SEIZURE THRESHOLD;

EID: 0345304249     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2003.08.043     Document Type: Article

References (54)

1. Alexander C.B., Ellmore T.M., Kokate T.G., Kirkby R.D. Further studies on anti- and proconvulsant effects of inhibitors of nitric oxide synthase in rodents. Eur J Pharmacol. 344:1998;15-25.
2. Benamar K., Xin L., Geller E.B., Adler M.W. Blockade of lipopolysaccharide induced fever by a μ-opioid receptor-selective antagonist in rats. Eur J Pharmacol. 40:2000;161-165.
3. Bhaduri J., Hota D., Acharya S.B. Role of prostaglandin synthesis inhibitors on chemically induced seizures. Indian J Exp Biol. 33:1995;677-681.
4. Blatteis C.M., Xin L., Quan N. Neuromodulation of fever apparent involvement of opioids . Brain Res Bull. 26:1991;219-223.
5. Carr D.B., Bergland R., Hamilton A., Blume H., Kasting N., Arnold M., Martin J.B., Rosenblatt M. Endotoxin-stimulated opioid secretion two secretory pools and feedback control in vivo . Science. 217:1982;845-848.
6. Del-Bel E.A., Oliveira J.A., Mishra P.K., Jobe P.C., Garcia-Cairasco N. Anticonvulsant and proconvulsant roles of nitric oxide in experimental epilepsy models. Braz J Med Biol Res. 30:1997;971-979.
7. de Vasconcelos A.P., Gizard F., Marescaux C., Nehlig A. Role of nitric oxide in pentylenetetrazol-induced seizures age-dependent effects in the immature rat . Epilepsia. 41:2000;363-371.
8. Di Giannuario A., Pieretti S., Luzi M., Loizzo A. Subchronic treatment with fragments of beta-endorphin prevents electroencephalographic seizures and behavioral alterations induced by centrally administered beta-endorphin in the rabbit. J Pharmacol Exp Ther. 268:1994;1040-1050.
9. Di Giannuario A., Pieretti S., Sagratella S., Loizzo A. Dexamethasone blocking effects on mu- and delta-opioid-induced seizures involves kappa-opioid activity in the rabbit. Neuropsychobiology. 43:2001;213-220.
10. Frenk H. Pro- and anticonvulsant actions of morphine and the endogenous opioids involvement and interactions of multiple opiate and non-opiate systems . Brain Res Rev. 6:1983;197-210.
11. Goumon Y., Bouret S., Casares F., Zhu W., Beauvillain J.C., Stefano G.B. Lipopolysaccharide increases endogenous morphine levels in rat brain. Neurosci Lett. 293:2000;135-138.
12. Hauss-Wegrzyniak B., Vraniak P.D., Wenk G.L. LPS-induced neuroinflammatory effects do not recover with time. Neuroreport. 11:2000;1759-1763.
13. Herman S.T. Epilepsy after brain insult targeting epileptogenesis . Neurology. 59:2002;S21-S26.
14. Hetier E., Ayala J., Bousseau A., Denefle P., Prochiantz A. Ameboid microglia cells and not astrocytes synthesize TNFα in Swiss mouse brain cultures. Eur J Neurosci. 2:1990;762-768.
15. Holaday J.W. Neuropeptides in shock and traumatic injury sites and mechanisms of action . Muller E.E., Macleod R.M. Neuroendocrine perspectives. 1984;161 Elsevier, Amsterdam.
16. Jayakumar A.R., Sujatha R., Paul V., Puviarasan K., Jayakumar R. Involvement of nitric oxide and nitric oxide synthase activity in anticonvulsive action. Brain Res Bull. 48:1999;387-394.
17. Jelenkovic A., Jovanovic M., Ninkovic M., Maksimovic M., Bokonjic D., Boskovic B. Nitric oxide (NO) and convulsions induced by pentylenetetrazol. Ann NY Acad Sci. 962:2002;296-305.
18. Koide S., Onishi H., Katayama M., Yamagami S. Endogenous methionine enkephalin may play an anticonvulsant role in the seizure susceptible EL mouse. Neurochem Res. 18:1993;1259-1262.
19. Kreutzberg G.W. Microglia a sensor for pathological events in the CNS . Trends Neurosci. 19:1996;312-318.
20. Lee S.C., Liu W., Dickson D.W., Brosnan C.F., Berman J.W. Cytokine production by human fetal microglia and astrocytes differential induction by lipopolysaccharide and IL-1β J Immunol. 150:1993;2659-2667.
21. Leib S.L., Kim Y.S., Black S.M., Tureen J.H., Tauber M.G. Inducible nitric oxide synthase and the effect of aminoguanidine in experimental neonatal meningitis. J Infect Dis. 177:1998;692-700.
22. Li Y., Uccelli A., Laxer K.D., Jeong M.C., Vinters H.V., Tourtellotte W.W., Hauser S.L. Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen. J Immunol. 158:1997;1428-1437.
23. Liu B., Du L., Ilong J.S. Naloxone protects rat dopaminergic neurons against inflammatory damage through inhibition of microglia activation and superoxide generation. J Pharmacol Exp Ther. 293:2000;607-617.
24. Liu B., Du L., Kong L.Y., Hudson P.M., Wilson B.C., Chang R.C., Abel H.H., Hong J.S. Reduction by naloxone of lipopolysaccharide-induced neurotoxicity in mouse cortical neuron-glia co-cultures. Neuroscience. 97:2000;749-756.
25. Liu B., Jiang J., Wilson B.C., Du L., Yang S., Wang Z., Wu G. Systemic infusion of naloxone reduces degeneration of rat substantia nigra dopaminergic neurons induced by intranigral injection of lipopolysaccharide. J Pharmacol Exp Ther. 295:2000;125-132.
26. Loscher W., Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2:1988;145-181.
27. Marangoz C., Bagirici F. Effects of L-arginine on penicillin-induced epileptiform activity in rats. Jpn J Pharmacol. 86:2001;297-301.
28. Matoth I., Pinto F., Sicsic C., Brenner T. Inhibitory effect of carbamazepine on inflammatory mediators produced by stimulated glial cells. Neurosci Res. 38:2000;209-212.
29. Matyszak M.K. Inflammation in the CNS balance between immunological privilege and immune response . Prog Neurobiol. 56:1998;19-35.
30. Medeiros F das C., Medeiros M.A., Rao V.S., Figueiredo E.G. Effects of misoprostol on pentylenetetrazol-induced seizures in mice. Arq Neuropsiquiatr. 55:1997;677-679.
31. Minghetti L., Levi G. Microglia as effector cells in brain damage and repair focus on prostanoids and nitric oxide . Prog Neurobiol. 54:1998;99-125.
32. Nidhi G., Balakrishnan S., Pandhi P. Role of nitric oxide in electroshock and pentylenetetrazole seizure threshold in rats. Methods Find Exp Clin Pharmacol. 21:1999;609-612.
33. Osonoe K., Mori N., Suzuki K., Osonoe M. Antiepileptic effects of inhibitors of nitric oxide synthase examined in pentylenetetrazol-induced seizures in rats. Brain Res. 663:1994;338-340.
34. Paoletti A.M., Piccirilli S., Costa N., Rotiroti D., Bagetta G., Nistico G. Systemic administration of N-omega-nitro-L-arginine methyl ester and indomethacin reduces the elevation of brain PGE2 content and prevents seizures and hippocampal damage evoked by LiCl and tacrine in rat. Exp Neurol. 149:1998;349-355.
35. Paul L., Fraifeld V., Kaplanski J. Evidence supporting involvement of leukotriens in LPS-induced hypothermia in mice. Am J Physiol. 276:1999;R52-R58.
36. Plata-Salaman C.R., Ilyin S.E., Turrin N.P., Gayle D., Flynn M.C., Romanovitch A.E., Kelly M.E., Bureau Y., Anisman H., McIntyre D.C. Kindling modulates the IL-1β system, TNF-α, TGF-β1, and neuropeptide mRNAs in specific brain regions. Mol Brain Res. 75:2000;248-258.
37. Porter R.J., Meldrum B.S. Antiseizure drugs. Katzung B.G. Basic and clinical pharmacology. 2001;395 Lange Medical Books/McGraw-Hill, New York.
38. Ramabadran K., Bansinath M. Endogenous opioid peptides and epilepsy. Int J Clin Pharmacol Ther Toxicol. 28:1990;47-62.
39. Santos F.A., Rao V.S.N. A study of the anti-pyretic effect of quinine, an alkaloid effective against cerebral malaria, on fever induced by bacterial endotoxin and yeast in rats. J Pharm Pharmacol. 50:1998;225-229.
40. Schroeder H., Becker A., Grecksch G., Schroeder U., Hoellt V. The effect of pentylenetetrazol kindling on synaptic mechanisms of interacting glutamatergic and opioid system in the hippocampus of rats. Brain Res. 811:1998;40-46.
41. Schuligoi R., Ulcar R., Peskar B.A., Amann R. Effect of endotoxin treatment on the expression on cyclooxygenase-2 and prostaglandin synthases in spinal cord, dorsal root ganglia, and skin of rats. Neuroscience. 116:2003;1043-1052.
42. Schwartz D., Engelhard D., Gallily R., Matoth I., Brenner T. Glial cells production of inflammatory mediators induced by streptococcus pneumoniae inhibition by pentoxifylline, low-molecular-weight heparin and dexamethasone . J Neurol Sci. 155:1998;13-22.
43. Simonato M., Romualdi P. Dynorphin and epilepsy. Prog Neurobiol. 51:1997;223-224.
44. Streit W.J., Gracber M.B., Kreutzberg G.W. Functional plasticity of microglia a review . Glia. 1:1998;301-307.
45. Temkin N.R., Jarnell A.D., Anderson G.D. Antiepileptogenic agents how close are we? Drugs. 61:2001;1045-1055.
46. Thompson A.J., Kermode A.G., Moseley I.F., MacManus D.G., McDonald W.I. Seizures due to multiple sclerosis seven patients with MRI correlation . J Neurol Neurosurg Psychiatry. 56:1993;1317-1320.
47. Turrin N.P., Gayle D., Ilyin S.E., Flynn M.C., Langhans W., Schwartz G.J., Plata-Salaman C.R. Pro-inflammatory and anti-inflammatory cytokine mRNA induction in the periphery and brain following intraperitoneal administration of bacterial lipopolysaccharide. Brain Res Bull. 54:2001;443-453.
48. Vezzani A., Moneta D., Richichi C., Aliprandi M., Burrows S.J., Ravizza T., Perego C., De Simoni M.G. Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis. Epilepsia. 43:2002;S30-S35.
49. Willmore L.J. Post-traumatic epilepsy cellular mechanisms and implications for treatment . Epilepsia. 31:1990;67-73.
50. Yehuda S., Mostofsky D.I. Circadian effects of beta-endorphin, melatonin, DSIP, and amphetamine on pentylenetetrazol-induced seizures. Peptides. 14:1993;203-205.
51. Yirmiya R., Pollak Y., Barak O., Avistur R., Ovadia H., Bette M., Weihe E., Weidenfeld J. Effects of antidepressant drugs on the behavioral and physiological responses to lipopolysaccharide (LPS) in rodents. Neuropsychopharmacology. 24:2001;531-544.
52. Yirmiya R., Rosen H., Donchin O., Ovadia H. Behavioral effects of lipopolysaccharide in rats involvement of endogenous opioids . Brain Res. 648:1994;80-86.
53. Yuhas Y., Nofech-Mozes Y., Weizman A., Ashkenazi S. Enhancement of pentylenetatrazole-induced seizures by Shigella dysenteriae in LPS-resistant C3H/HeJ mice role of the host response . Med Microbiol Immunol. 190:2002;173-178.
54. Yuhas Y., Weizman A., Dinari G., Ashkenazi S. An animal model for the study of neurotoxicity of bacterial products and application of the model to demonstrate that Shiga toxin and lipopolysaccharide cooperate in inducing neurologic disorders. J Infect Dis. 171:1995;1244-1249.